Munyori: Janice Evans
Zuva Rekusika: 25 Chikunguru 2021
Gadziridza Zuva: 21 Ndira 2025
Anonim
Ivosidenib for Advanced IDH1-Mutated CCA
Vhidhiyo: Ivosidenib for Advanced IDH1-Mutated CCA

Zvemukati

Ivosidenib inogona kukonzera rakakomba kana kutyisidzira hupenyu boka rezviratidzo zvinonzi kusiyanisa chirwere. Chiremba wako anozokutarisa nemazvo kuti aone kana iwe uri kuvandudza iyi syndrome. Kana iwe ukasangana nechimwe cheanotevera zviratidzo, danaidza chiremba wako nekukasira: fivha, kukosora, kuputika, kuwedzera uremu nekukasira, kuderera kwekuita weti, kuzvimba kwemaoko kana makumbo, dzungu kana huremu hurema, kufema kwekufema, kana kunetseka kufema. Zviratidzo izvi zvinogona kuitika kusvika pamwedzi mitatu mushure mekutanga kurapwa neivosidenib. Pakutanga chiratidzo chekuti urikudziridza kusiyanisa chirwere, chiremba wako anokupa mishonga yekurapa chirwere ichi, uye anogona kukuudza kuti rega kutora ivosidenib kwenguva yakati.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mimwe bvunzo usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune ivosidenib.

Chiremba wako kana wemishonga achakupa gwaro reruzivo rwevarwere (reMedicine Gwara) paunotanga kurapwa neivosidenib uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti utore Gwaro reMishonga.


Ivosidenib inoshandiswa kurapa imwe mhando yeacute myeloid leukemia (AML; mhando yekenza inotanga mumasero machena eropa) yakadzoka kana isina kuvandudzwa mushure mekurapwa kwekare. Ivosidenib inoshandiswawo kurapa rumwe rudzi rwe AML kune vamwe vanhu vakuru vanopfuura makore makumi manomwe nemashanu ekuberekwa sekutanga kurapwa. Ivosidenib iri mukirasi yemishonga cad IDH1 inhibitors. Inoshanda nekuderedza kana kumisa kukura kwemasero ekenza.

Ivosidenib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva. Ita kwete tora nechikafu chine mafuta akawanda (senge chikafu chakakangwa kana chikafu chinokurumidza). Tora ivosidenib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora ivosidenib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.


Kana iwe ukarutsa mushure mekutora ivosidenib, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako anogona kudzora dosi yako kana kumbomira kurapwa kwenguva pfupi kana zvachose kana ivosidenib zvichienderana nemhinduro yako pakurapwa kana chero mhedzisiro yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora ivosidenib,

  • udza chiremba wako uye wemishonga kana iwe uri weergoria kune ivosidenib, chero mimwe mishonga, kana chero chinhu chinowanikwa mumapiritsi eivosidenib. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: amiodarone (Nexterone, Pacerone), carbamazepine (Equetro, Tegretol, Teril, vamwe), clarithromycin, diltiazem (Cardizem, Cartia, Diltzac, Tiazac, vamwe), efavirenz (Sustiva, muAtripla, mu Symfi), erythromycin (Eryc), fluconazole (Diflucan), indinavir (Crixivan), itraconazole (Onmel, Sporanox, Tolsura), ketoconazole, mishonga yekudzivirira pamuromo yakadai seimwe ('mapiritsi ekudzivirira kubereka'), zvigamba, uye zvindori zvemadzimai emukadzi , nelfinavir (Viracept), nevirapine (Viramune), phenobarbital, phenytoin (Dilantin, Phenytek), pioglitazone (Actos), procainamide, quinidine (muNuedexta), rifabutin (Mycobutin), rifampin (Rifadin, Rifatin, (Norvir, muKaletra, muViekira), saquinavir (Fortovase, Invirase), telithromycin (Ketek), uye verapamil (Calan, Verelan, muTarka). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana neivosidenib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
  • udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's Wort.
  • udza chiremba wako kana iwe kana ani zvake mumhuri yako ane kana akambove nenguva yakareba yeQT (mamiriro anowedzera njodzi yekuita kurova kwemoyo zvisina kujairika kunogona kukonzera kupera simba kana kufa kamwe kamwe); kana iwe wakambove kana wakambove neinononoka kana isina kujairika kurova kwemoyo kana mamwe matambudziko emoyo; mashoma eropa mazinga esodium, potasium, kana magnesium; zvinetso zvehurongwa hwemitsipa; chirwere chechiropa, kusanganisira cirrhosis; kana kana iwe uri kugamuchira dialysis kurapwa kana iwe uine kana wakambove uine chirwere cheitsvo.
  • udza chiremba wako kana iwe uri nepamuviri kana kuronga kuva nepamuviri, kana uri kuyamwisa. Iwe unofanirwa kuziva kuti ivosidenib inogona kudzikisira kushanda kwemahomoni ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, kana majekiseni) paunenge uchitora mushonga uyu. Taura nachiremba wako nezve kushandisa imwe nzira yekudzivirira kuberekwa. Kana iwe ukava nepamuviri uchitora ivosidenib, dana chiremba wako nekukurumidza. Ivosidenib inogona kukonzera kukuvara kwemucheche.
  • udza chiremba wako kana uchiyamwisa. Usamwisa mukaka panguva yekurapwa kwako neivosidenib uye kwemwedzi mumwe mushure mekupedzisira kwedosi.

Taura nachiremba wako nezve kudya mazambiringa uye kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.


Ita shuwa kuti unonwa mvura yakawanda kana zvimwe zvinwiwa zuva rega rega iwe paunenge uchitora ivosidenib.

Kana yako inotevera dosi inokodzera mumaawa gumi nemaviri kana kupfuura, tora iyo yakarasika dhizai nekukurumidza kana uchinge uchayeuka izvozvo. Nekudaro, kana iyo inotevera dhizaini ichatorwa mune asingasviki maawa gumi nemaviri, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Ivosidenib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • musoro
  • kuneta
  • kubatana kana kurwadziwa kwemhasuru
  • manyoka
  • kuvimbiswa
  • kurutsa
  • kusvotwa
  • kurasikirwa nenzara
  • kurwadziwa mumuromo uye maronda
  • kurwadziwa nemudumbu

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • dzungu, musoro wakareruka, kana kupera simba
  • kushaya simba kana kurira kwekunzwa mumakumbo, maoko, kana kumusoro muviri; chiveve uye kurwadziwa kune rimwe divi kana mativi ese emuviri; shanduko mukugona kwako kuona, kubata, kunzwa, kana kuravira; kupisa kana kupaza kwekunzwa; kana kunetseka kufema
  • kurwadziwa pachipfuva

Ivosidenib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chiremba wako acharaira bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana kenza yako inogona kurapwa ne ivosidenib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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