Selumetinib

Zvemukati

• Usati watora selumetinib,
• Selumetinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Selumetinib inoshandiswa kurapa neurofibromatosis mhando 1 (NF1; chirwere chetsinga chinokonzeresa kuti mamota akure pamitsipa) muvana vane makore maviri ekuberekwa uye vakuru vane plexiform neurofibromas (PN; mamota akapfava) asingakwanise kubviswa zvachose nekuvhiyiwa. Selumetinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza kuti mamota anokura. Izvi zvinobatsira kumira kana kunonoka kukura kwechirwere.

Selumetinib inouya sekapuleti kutora nemuromo. Inowanzo kutorwa kaviri pazuva pane isina chinhu mudumbu. Usadye chero chikafu maawa maviri pamberi kana kwe1 awa mushure meimwe dozi. Tora selumetinib panguva dzakatenderedza nguva imwechete mazuva ese, anenge maawa gumi nemaviri akaparadzaniswa. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora selumetinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza macapsule akazara nemvura; usavhure, kutsenga, kana kuapwanya.

Kana iwe ukarutsa mushure mekutora selumetinib, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako anogona kudzora dhizaini yako kana kwechinguva kana zvachose kumisa kurapwa kwako kana iwe ukawana mamwe mhedzisiro. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako ne selumetinib.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora selumetinib,

• udza chiremba wako uye wemishonga kana iwe uri weergoriki kune selumetinib, chero mimwe mishonga, kana chero chipi zvacho chemusanganiswa wem selumetinib capsules. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: anticoagulants ('blood thinner') senge warfarin (Coumadin, Jantoven); antifungals senge fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), uye voriconazole (Vfend); aprepitant (Simbisa); clarithromycin (Biaxin, muPrevpac); clopidogrel (Plavix); corticosteroids yakadai betamethasone (Celestone), budesonide (Entocort), cortisone (Cortone), dexamethasone (Decadron, Dexpak, Dexasone, vamwe), hydrocortisone (Cortef, Hydrocortone), methylprednisolone (Medrol, Meprolone, vamwe), prednisolone (Prelisolone (Prelisolone) ), uye prednisone (Rayos); diltiazem (Cardizem, Dilacor, Tiazac, nevamwe); erythromycin (EES, E-Mycin, Erythrocin); mimwe mishonga yeHIV inosanganisira indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, muKaletra), uye saquinavir (Fortovase, Invirase); idelalisib (Zydelig); nefazodone; phenobarbital; rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, muRifamate, muRifater); verapamil (Calan, Covera); uye vhitamini E zvinowedzera. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana iwe kana wakambove nematambudziko ekuona, kunetseka kumedza, kana chirwere chemoyo kana chechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kana iwe uronga nezve kubereka mwana. Kana iwe uri munhukadzi, iwe unozofanirwa kutora kutora nhumbu usati watanga kurapwa uye kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapwa kwako uye kweinenge 1 vhiki mushure meyako yekupedzisira dosi. Kana iwe uri murume, iwe nemumwe wako munofanira kushandisa kuberekwa panguva yekurapa kwenyu ne selumetinib uye kwevhiki imwe mushure meyadhi yenyu yekupedzisira. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa panguva yekurapa kwako. Kana iwe kana mumwe wako mukava nepamuviri muchitora selumetinib, danai chiremba wako nekukasira. Selumetinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa iwe paunenge uchitora selumetinib uye kwevhiki rimwe mushure mekupedzisira muyero.

Dzivisa kudya grapefruit kana kunwa muto wemazambiringa apo uchinwa mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana iri mukati maawa matanhatu emutero unotevera, svetuka dhosi rakarasika uye enderera yako yenguva dzose dosing chirongwa. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Selumetinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kurutsa
• kuvimbiswa
• kurwadziwa nemudumbu
• kusvotwa
• ganda rakaoma
• musoro
• maronda emumuromo
• kuvava
• kutsvuka kwakatenderedza nzara
• mhino kubuda ropa
• kuneta
• kurasikirwa nenzara
• kurasikirwa bvudzi kana bvudzi bvudzi shanduko

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kupindwa nechando
• kubuda ropa zvisina kujairika
• ganda rakachenuruka kana kuneta
• kusaona zvakanaka; kurasikirwa kwemaonero; nzvimbo dzine rima muchiratidzo chako; kana kumwe kuchinja kwemaonero
• manyoka
• mapundu, mapundu eganda kana kubvisa
• kurwadziwa kwemhasuru, kurwadziwa, kana kushaya simba; kana weti yakasviba
• kukosora kana kufema; mweya wekufema; kuzvimba kwemakumbo nemakumbo; kana kuneta zvakanyanya

Selumetinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Usabvisa iyo desiccant (kadiki kapaketi inosanganisirwa nemakapisi kuti anye hunyoro) kubva mubhodhoro rako.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako, chiremba wemaziso, uye rabhoritari. Chiremba wako acharaira kumwe kuongorora kwebazi, kusanganisira bvunzo dzemaziso, usati, panguva, uye mushure mekurapwa kwako kuti utarise mhinduro yemuviri wako kune selumetinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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