Munyori: Virginia Floyd
Zuva Rekusika: 5 Nyamavhuvhu 2021
Gadziridza Zuva: 17 Mbudzi 2024
Anonim
ASCO: Alpelisib Plus Fulvestrant for PIK3CA-Mutated Breast Cancer After Failure of CDK4/6 Inhibitors
Vhidhiyo: ASCO: Alpelisib Plus Fulvestrant for PIK3CA-Mutated Breast Cancer After Failure of CDK4/6 Inhibitors

Zvemukati

Alpelisib inoshandiswa musanganiswa nefulvestrant (Faslodex) kurapa imwe mhando yekenza yemazamu yakapararira kumatishu ari padyo kana zvimwe zvikamu zvemuviri muvakadzi vakatopfuura kuenda kumwedzi ('' shanduko yehupenyu, '' kupera kwekuenda kumwedzi. nguva) kana muvarume, vane gomarara rakawedzera panguva kana mushure meimwe kurapwa. Alpelisib ari mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira zviratidzo zvinokonzeresa kuti maseru ekenza awande. Izvi zvinobatsira kumisa kupararira kwemasero ekenza.

Alpelisib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa nechingwa kamwe chete pazuva kwenguva yakareba sekunge chiremba wako achikurudzira kurapwa. Tora alpelisib panenge panguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora alpelisib chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya. Usatora piritsi rakatyoka, ratsemuka, kana kukuvara.


Kana iwe ukarutsa mushure mekutora alpelisib, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako anogona kudzikisa dhizaini yako yealpelisib, kukubata iwe nemimwe mishonga, kana kukanganisa kana kumisa kurapwa kwako kana iwe ukawana mamwe mhedzisiro. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapa kwako nealpelisib.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora alpelisib,

  • udza chiremba wako uye wemishonga kana iwe uri weergoria kune alpelisib, chero mimwe mishonga, kana chero chinhu chinowanikwa mumapiritsi ealpelisib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, kana izvo zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero cheanotevera: carbamazepine (Carbatrol, Equetro, Tegretol, vamwe), cyclosporine (Gengraf, Neoral, Sandimmune), efavirenz (Sustiva, muAtripla, Symfi), eltrombopag (Promacta), nevirapine (Viramune), phenobarbital , phenytoin (Dilantin, Phenytek), pioglitazone (Actos, muOseni, Duetact), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, muRifamate, Rifater), uye warfarin (Coumadin, Jantoven). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana nealpelisib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isingaonekwe pane ino runyorwa.
  • udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya curcumin uye St. John's wort.
  • udza chiremba wako kana iwe wakamboita kuputika nemaronda matsvuku pamiromo, mukanwa kana ganda, kana kudurura, ganda rinoputika; kana kuva kana kumbove nechirwere cheshuga kana cheitsvo.
  • udza chiremba wako kana iwe kana mumwe wako ane pamuviri, kana kuronga kuva nepamuviri. Iwe kana mumwe wako haufanire kuve nepamuviri panguva yekurapwa kwako nealpelisib. Kana iwe uri mukadzi anogona kuve nepamuviri, iwe uchafanirwa kuve nemimba yekubata usati watanga kurapwa, uye iwe unofanirwa kushandisa anoshanda ekuberekwa nekudzivirira panguva yekurapa kwako uye kwevhiki rimwe mushure meyako yekupedzisira dosi. Kana iwe uri murume ane mukadzi mukadzi uyo anogona kuve nepamuviri, shandisa kondomu panguva yekurapwa kwako uye kwevhiki rimwe mushure mekupedzisira kwako dosi. Kana iwe kana mumwe wako mukava nepamuviri muchitora alpelisib, danai chiremba wako.
  • udza chiremba wako kana iwe uchiyamwisa. Chiremba wako anogona kukuudza kuti usayamwisa-mwana panguva yekurapwa kwako uye kwevhiki rimwe mushure mekupedzisira kwezita rako.
  • iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume nevakadzi. Taura nachiremba wako nezve njodzi dzekutora alpelisib.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.


Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Nekudaro, kana anopfuura maawa gumi nepfumbamwe apfuura kubva pawakarasa dhizaini, svetuka iro rakarasika uye ramba uchiita yako yenguva dzose dosing chirongwa Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Alpelisib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kusvotwa
  • kurutsa
  • kuneta zvakanyanya
  • kuderera kwechido
  • chinja munzira iyo zvinhu zvinonaka
  • kuonda
  • marwadzo emudumbu
  • chirungurira
  • kurasikirwa nevhudzi
  • musoro
  • kuvava
  • ganda rakaoma
  • muromo wakaoma
  • kuoma kwechikadzi
  • kupindwa nechando
  • kuzvimba kwemaoko kana makumbo

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchida kurapwa,

  • dambudziko kumedza kana kufema, kukurumidza, kufashaira, kupisa muviri, kana kurova kwemoyo nekukurumidza
  • kuputika, kubvisa ganda, kuputika, ganda rakatsvuka, maronda pamiromo kana mumuromo, fivha, zviratidzo zvakaita sefuru.
  • yakawedzera nyota, yakaoma mukanwa, kuwedzerwa chishuwo nekudzikira uremu, kuita weti kakawanda kana hombe yakawanda kupfuura zvakajairwa, mweya unonhuwa kunge muchero
  • kufema, kukosora, kurwadziwa pachipfuva, kunetseka kufema
  • manyoka akakomba, kuoma muromo, kurwadza, kushaya simba, kuderera kwekuita weti, kuzvimba kwemakumbo kana makumbo
  • kazhinji, zvinorwadza, kana kukurumidza kuita weti

Alpelisib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.


Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

  • kusvotwa
  • kushaya simba
  • mapundu
  • yakawedzera nyota uye chishuwo
  • muromo wakaoma
  • kuita weti kakawanda kana kuwanda

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana kenza yako inogona kurapwa nealpelisib. Chiremba wako anozorairawo kumwe kuongorora kwebazi kare uye panguva yekurapwa kwako kuti utarise mhinduro yemuviri wako kuna alpelisib.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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Yekupedzisira Yakagadziridzwa - 07/15/2019

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