Tolvaptan (chirwere cheitsvo)

Zvemukati

• Usati watora tolvaptan (Jynarque),
• Tolvaptan (Jynarque) inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, dana chiremba wako nekukurumidza:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

Tolvaptan (Jynarque) inogona kukonzera kukuvara kwechiropa, dzimwe nguva zvakakomba zvakakwana zvekuda kuisirwa chiropa kana kukonzera rufu. Udza chiremba wako kana iwe wakambove nematambudziko echiropa, kusanganisira hepatitis. Chiremba wako anogona kukuudza kuti usatore tolvaptan (Jynarque). Chiremba wako anozoraira bvunzo dzemarabhoritari nguva dzose usati uye panguva yekurapa kwako kuti uone kana tolvaptan (Jynarque) iri kukanganisa chiropa chako. Chiremba wako anogona kukuudza kuti haufanire kugamuchira mushonga uyu kana bvunzo dzichiratidza kuti une matambudziko echiropa. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, dana chiremba wako nekukurumidza: kusvotwa, kurutsa, kuneta zvakanyanya, kubuda ropa kusingawanzo kana kupwanya, kushaya simba, kurasikirwa nenzara, kurwadziwa nechekumusoro kurudyi mudumbu, yero yeganda kana maziso , weti-yakasviba weti, mapundu, kuchenesa, kana zviratidzo zvakaita sefuru.

Nekuda kwenjodzi nemushonga uyu, tolvaptan (Jynarque) inowanikwa chete kuburikidza nehurongwa hwakakosha hwekuparadzira. Chirongwa chinonzi Jynarque Risk Evaluation uye Mitigation Strategies (REMS) chakamisikidzwa kudzikisa njodzi dzekutora tolvaptan (Jynarque). Chiremba wako uye wemishonga wako anofanirwa kunyoreswa neiyo Jynarque REMS chirongwa. Kumbira chiremba wako kuti uwane rumwe ruzivo nezvechirongwa ichi uye kuti unozogamuchira sei mushonga wako. Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mimwe bvunzo usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune tolvaptan (Jynarque).

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa netolvaptan (Jynarque) uye nguva imwe neimwe paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi yekutora tolvaptan (Jynarque).

Tolvaptan (Jynarque) inoshandiswa kudzikisira kuwedzera kwekuita kweitsvo mune vamwe varwere vane autosomal inotyisa polycystic chirwere cheitsvo (ADPKD; imwe mhando yechirwere cheitsvo chakagarwa nhaka). Tolvaptan (Jynarque) iri mukirasi yemishonga inonzi vasopressin V₂ vanopikisa vanogamuchira. Inoshanda nekuwedzera huwandu hwemvura yakaburitswa kubva mumuviri kunge weti uye inoderedza kukura kwema cysts muitsvo. Kubvisa fluid kubva mumuviri uye kunonoka kukura kwema cysts kunobatsira kudzora kuwedzera kwekuita kweitsvo.

Tolvaptan inowanikwawo sehwendefa (Samsca) kurapa yakaderera ropa mazinga esodhiya mune vanhu vane moyo kukundikana kana mamwe mamiriro. Iyi monograph inopa chete ruzivo nezve tolvaptan mapiritsi (Jynarque) yekudzora kuwedzera kwekuita kweitsvo mune varwere vane ADPKD. Kana iwe urikushandisa uyu mushonga kurapa akadzika masosiamu muropa, verenga monograph yakanzi tolvaptan (yakaderera ropa sodium).

Tolvaptan (Jynarque) inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kaviri pazuva, piritsi rimwe mangwanani uye piritsi rimwe chete maawa masere gare gare, uine kana usina chikafu. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora tolvaptan (Jynarque) chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Chiremba wako angangotanga iwe pane yakaderera dosi ye tolvaptan (Jynarque) uye zvishoma nezvishoma wedzera yako dosi.

Chiremba wako angangoda kudzikisa dosi yako kana iwe ukawana mamwe mhedzisiro. Zvakakosha kuti iwe uudze chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora tolvaptan (Jynarque),

• udza chiremba wako uye wemishonga kana uri weergoria kune tolvaptan (Jynarque, Samsca), chero mimwe mishonga, kana chero chinhu chinowanikwa mumatafura etolvaptan. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako kana iwe uri kutora mamwe maantifungal akadai ketoconazole (Nizoral) kana itraconazole (Sporanox); clarithromycin (Biaxin); kana mimwe mishonga yeHIV yakadai seininavir (Crixivan), lopinavir (Kaletra), nelfinavir (Viracept), ritonavir (Norvir), kana saquinavir (Invirase); conivaptan (Vaprisol); kana nefazodone. Chiremba wako anogona kukuudza kuti usatore tolvaptan (Jynarque) kana uri kutora imwe kana yakawanda yemishonga iyi.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: atorvastatin (Lipitor, muCaduet), bosentan (Tracleer), desmopressin (dDAVP, Minirin, Noctiva), digoxin (Lanoxin), fluconazole (Diflucan); furosemide (Lasix), glyburide (Diabeta, Glynase), lovastatin (Altoprev), methotrexate (Otrexup, Rasuvo, Trexall, Xatmep), nateglinide (Starlix), pravastatin (Pravachol), repaglinide (Prandin), rifampin (Rifadin, Rifadin ), rosuvastatin (Crestor), uye simvastatin (Zocor, muVytorin). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana ne tolvaptan (Jynarque), saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kana iwe uine chero mamiriro ezvinhu ataurwa muchikamu CHINOKOSHA CHENYENZISO, kana iwe kana wakambove nehupamhi hwe sodium muropa rako, kana uchinetseka kuita weti kana kutadza kuita weti, kana wanga uchirutsa zvakanyanya kana kuita manyoka kana kufunga kuti ungave usina mvura, kana kana iwe usingakwanise kuona kuti une nyota. Chiremba wako anogona kukuudza kuti usatore tolvaptan (Jynarque).
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora tolvaptan (Jynarque), fonera chiremba wako. Iwe haufanire kuyamwa paunenge uchitora tolvaptan (Jynarque).

Iwe unozofanirwa kunwa mvura yakakwana paunenge uchitora tolvaptan (Jynarque) kuti usazonzwa nyota kana kupera mvura.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.

Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Tolvaptan (Jynarque) inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• nyota
• muromo wakaoma
• kazhinji, kuwedzeredza weti
• chirungurira
• kuderera kwechido

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, dana chiremba wako nekukurumidza:

• manyoka
• kutadza kunwa zvakajairika
• dzungu
• kupera simba
• kuderera kwekuita weti
• kushaya simba
• kutsimwaira
• kuvhiringidzika
• kuonda
• kukurumidza kana kurova kurova kwemoyo
• kuzvimba kwechiso, huro, rurimi, miromo, maziso, maoko, tsoka, makumbo, kana makumbo ezasi
• hoarseness
• mikoko

Tolvaptan (Jynarque) inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

• kunyanyisa kuita weti
• nyota yakanyanyisa
• dzungu
• kupera simba

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira kumwe kuongorora kwebazi kuti atarise mhinduro yemuviri wako kutolvaptan (Jynarque).

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Jynarque^®