Lisocabtagene Maraleucel Jekiseni

Zvemukati

• Usati wagamuchira lisocabtagene maraleucel,
• Lisocabtagene maraleucel inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Lisocabtagene maraleucel jekiseni inogona kukonzeresa kana kutyisidzira hupenyu maitiro anonzi cytokine release syndrome (CRS). Chiremba kana mukoti anozokutarisa zvakanyatsonaka panguva yako yekumukiswa uye kweanenge mavhiki mana mushure. Udza chiremba wako kana iwe uine chirwere chekuvhiringidza kana iwe uine kana uchifunga kuti iwe unogona kunge uine chero hutachiona hutachiona izvozvi. Iwe unozopihwa mishonga maminetsi makumi matatu kusvika makumi matanhatu usati wanyudzwa kuti ubatsire kudzivirira kusangana lisocabtagene maraleucel. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge wamunyudzwa, udza chiremba wako nekukasira: fivha, kutonhora, kukurumidza kana kusagadzikana kwemoyo, kurwadziwa kwemhasuru, kuzunza, manyoka, kuneta, kushaya simba, kunetseka kufema, kufema, kukosora, kuvhiringidzika, kusvotwa, kurutsa, dzungu, kana musoro wakareruka.

Lisocabtagene maraleucel jekiseni inogona kukonzeresa kana kutyisidzira hupenyu hwepakati tsinga maitiro. Aya maitiro anogona kuitika mushure mekurapwa ne lisocabtagene maraleucel. Udza chiremba wako kana iwe wakambove nekugumburwa, sitiroko, kana kurasikirwa ndangariro. Kana ukasangana nechimwe chezviratidzo zvinotevera, udza chiremba wako nekukurumidza: kutemwa nemusoro, dzungu, kunetseka kurara kana kuramba wakarara, kusagadzikana, kuvhiringidzika, kushushikana, kuzunza kusingadzoreki kwechikamu chemuviri, kurasikirwa kwekuziva, kushungurudzika, kugwinha, kurasikirwa kuenzanisa, kana kunetseka kutaura.

Lisocabtagene maraleucel jekiseni inongowanikwa chete kuburikidza neyakaganhurirwa kugovera chirongwa. Chirongwa cheBreyanzi REMS (Risk Evaluation uye Mitigation Strategic) chakagadzwa nekuda kwenjodzi dzeCRS uye neurological chepfu. Unogona chete kugamuchira mishonga kubva kuna chiremba uye nzvimbo yehutano inotora chikamu muchirongwa. Kumbira chiremba wako kana iwe uine chero mibvunzo nezvechirongwa ichi.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Mishonga Inotungamira) paunotanga kurapwa ne lisocabtagene maraleucel uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Lisocabtagene maraleucel inoshandiswa kurapa mamwe marudzi makuru eB-cell lymphoma (rudzi rwekenza inotanga mumasero machena eropa) kune vanhu vakuru vane gomarara rakadzoka kana risingateereri kune mamwe marapirwo maviri. Lisocabtagene maraleucel iri mukirasi yemishonga inonzi autologous cellular immunotherapy, mhando yemishonga yakagadzirirwa kushandisa masero kubva muropa rega murwere. Inoshanda nekukonzeresa immune system (boka remasero, zvinyama, uye nhengo zvinodzivirira muviri kubva pakurwiswa nemabhakitiriya, mavairasi, cancer maseru, nezvimwe zvinhu zvinokonzeresa chirwere) kurwisa maseru egomarara.

Lisocabtagene maraleucel inouya sekumiswa (mvura) kuti ijekisirwe mukati (mutsinga) nachiremba kana mukoti muhofisi yechiremba kana nzvimbo yekumukisa. Iyo inowanzo kupihwa semaviri infusions pamusoro payo yakazara nguva inosvika pamaminitsi makumi matatu seimwe-yenguva-dhiza Usati wagamuchira lisocabtagene maraleucel dose, chiremba wako kana mukoti achapa mamwe makemikari mishonga kugadzirira muviri wako kune lisocabtagene maraleucel.

Pamberi pekuti jekiseni rerisocabtagene maraleucel rinofanira kupihwa, semuenzaniso yemasero machena eropa anozotorwa kuchitokisi chekuunganidza masero uchishandisa nzira inonzi leukapheresis (chirongwa chinobvisa masero machena eropa kubva mumuviri). Nekuti mushonga uyu unogadzirwa kubva kumaseru ako wega, unofanirwa kupihwa iwe chete. Izvo zvakakosha kuti uve nenguva uye kuti usarasikirwe yako yakarongedzwa maseru ekuunganidzwa kusarudzwa (s) kana kugamuchira yako yekurapa dosi. Iwe unofanirwa kuronga kugara padhuze nekwawakagamuchira yako lisocabtagene maraleucel kurapwa kweinokwana mavhiki mana mushure medosi yako.Anopa hutano hwako anotarisa kuti aone kana kurapwa kwako kuri kushanda uye nekukutarisa iwe kune chero zvingangoitika mhedzisiro. Taura nachiremba wako nezvekuti ungagadzirira sei leukapheresis uye zvaunotarisira panguva uye mushure mekuita.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wagamuchira lisocabtagene maraleucel,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune lisocabtagene maraleucel, chero mimwe mishonga, kana chero chimwe chezvisanganiswa mu lisocabtagene maraleucel. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove kana wakambove nehutachiona hwehepatitis B kana chirwere chechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Iwe unozofanirwa kuve nemimba yekuyedza usati watanga lisocabtagene maraleucel. Kana iwe ukava nepamuviri iwe uchigamuchira lisocabtagene maraleucel, dana chiremba wako nekukasira.
• iwe unofanirwa kuziva kuti lisocabtagene maraleucel jekiseni inogona kukutsira iwe uye kukonzeresa kuvhiringidzika, kushaya simba, dzungu, pfari, uye matambudziko ekubatanidza. Usatyaire mota kana kushandisa michina kweanokwana masvondo masere mushure meiyo lisocabtagene maraleucel dose.
• usape ropa, nhengo, zvinyama, kana masero ekuisirwa mushure mekunge wagamuchira lisocabtagene maraleucel jekiseni.
• bvunza nachiremba wako kuti uone kana iwe uchida kugamuchira chero majekiseni. Hauna majekiseni pasina kutaura nachiremba wako kweanenge mavhiki matanhatu usati watanga chemotherapy, panguva yako lisocabtagene maraleucel kurapwa, uye kusvikira chiremba wako akakuudza kuti immune system yako yapora.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Ukatadza nguva yekutora masero ako, unofanirwa kufonera chiremba wako nenzvimbo yekuunganidza ipapo ipapo. Ukasuwa musangano kuti ugamuchire yako lisocabtagene maraleucel dose, unofanira kufonera chiremba wako ipapo ipapo.

Lisocabtagene maraleucel inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kuvimbiswa
• kurwadziwa nemudumbu
• kurasikirwa nenzara
• mapundu
• chiveve, kurwadziwa, kurira, kana kutsva kunzwa mutsoka kana maoko

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kunzwa kuneta
• kupwanya kana kubuda ropa
• fivha, huro, chironda, kana zvimwe zviratidzo zvehutachiona
• kuvhiringidzika
• nekukurumidza kana zvisina kujairika kurova kwemoyo

Lisocabtagene maraleucel inogona kuwedzera njodzi yako yekuva nekenza. Taura nachiremba wako nezve njodzi dzekugamuchira uyu mushonga.

Lisocabtagene maraleucel inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza zvese zvakagadzwa nachiremba wako, nzvimbo yekuunganidzira masero, uye rabhoritari. Chiremba wako anogona kuraira kumwe kuongorora kwerebhu kare, panguva, uye mushure mekurapwa kwako kuti utarise mhinduro yemuviri wako kune lisocabtagene maraleucel jekiseni.

Usati waita chero bvunzo yerabhoritari, udza chiremba wako uye vashandi veirabhoritari kuti urikugamuchira lisocabtagene maraleucel.

Bvunza wako wemishonga chero mibvunzo iwe unayo nezve lisocabtagene maraleucel.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Breyanzi^®