Idecabtagene Vicleucel jekiseni

Zvemukati

• Usati wagamuchira idecabtagene vicleucel jekiseni,
• Idecabtagene vicleucel inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Idecabtagene vicleucel jekiseni inogona kukonzeresa kana kutyisidzira hupenyu maitiro anonzi cytokine release syndrome (CRS). Chiremba kana mukoti anozokutarisa zvakanyatsonaka panguva yako yekumukiswa uye kweanenge mavhiki mana mushure. Udza chiremba wako kana iwe uine chirwere chekuvhiringidza kana iwe uine kana uchifunga kuti iwe unogona kunge uine chero hutachiona hutachiona izvozvi. Iwe unozopihwa mishonga maminetsi makumi matatu kusvika makumi matanhatu usati wanyudzwa kuti ubatsire kudzivirira maitiro kune idecabtagene vicleucel. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge wamunyudzwa, udza chiremba wako nekukasira: fivha, kutonhora, kukurumidza kana kusagadzikana kwemoyo, kurwadziwa kwemhasuru, kuzunza, manyoka, kuneta, kushaya simba, kunetseka kufema, kufema, kukosora, kuvhiringidzika, kusvotwa, kurutsa, dzungu, kana musoro wakareruka.

Idecabtagene vicleucel jekiseni inogona kukonzeresa kana kutyisidzira hupenyu hwepakati tsinga maitiro. Aya maitiro anogona kuitika mushure mekurapwa ne idecabtagene vicleucel. Udza chiremba wako kana iwe wakambove nekugumburwa, sitiroko, kana kurasikirwa ndangariro. Kana ukasangana nechimwe chezviratidzo zvinotevera, udza chiremba wako nekukurumidza: kutemwa nemusoro, dzungu, kunetseka kurara kana kuramba wakarara, kusagadzikana, kuvhiringidzika, kushushikana, kuzunza kusingadzoreki kwechikamu chemuviri, kurasikirwa kwekuziva, kushungurudzika, kugwinha, kurasikirwa kuenzanisa, kana kunetseka kutaura.

Idecabtagene vicleucel jekiseni inogona kukonzera kuderera kwakanyanya muhuwandu hwemamwe marudzi emasero eropa muropa rako. Izvi zvinogona kukonzera zvimwe zviratidzo uye zvinogona kuwedzera njodzi yekuti uchave nehutachiona hwakakomba kana kubuda ropa. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiita, taurira chiremba wako nekukasira: kupisa muviri, kunzwa kuneta, kana kupwanya kana kubuda ropa.

Idecabtagene vicleucel inowanikwa chete kuburikidza nehurongwa hwakakosha hwekuparadzira. Iyo Abecma REMS chirongwa (Risk Kuongorora uye Kudzikisira Strategic) yakagadzwa nekuda kwenjodzi dzeCRS, yepakati tsinga system, uye maseru eropa matambudziko. Unogona chete kugamuchira mishonga kubva kuna chiremba uye nzvimbo yehutano inotora chikamu muchirongwa. Kumbira chiremba wako kana iwe uine chero mibvunzo nezvechirongwa ichi.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa ne idecabtagene vicleucel uye nguva yega yega paunozadza tsamba yako Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Idecabtagene vicleucel jekiseni rinoshandiswa kurapa mamwe marudzi eakawanda myeloma (rudzi rwekenza yemongo wemapfupa) kune vanhu vakuru vane gomarara rakadzoka kana risingateereri kune mamwe marapirwo mana. Idecabtagene vicleucel jekiseni iri mukirasi yemishonga inonzi autologous cellular immunotherapy, mhando yemishonga yakagadzirirwa kushandisa maseru kubva muropa reropa rake. Inoshanda nekukonzeresa immune system (boka remasero, zvinyama, uye nhengo zvinodzivirira muviri kubva pakurwiswa nemabhakitiriya, mavairasi, cancer maseru, nezvimwe zvinhu zvinokonzeresa chirwere) kurwisa maseru egomarara.

Idecabtagene vicleucel jekiseni rinouya sekumisa (mvura) kuiswa jekiseni (kupinda mutsinga) nachiremba kana mukoti muhofisi yechiremba kana nzvimbo yekumukisa. Inowanzo kupihwa pamusoro penguva yakazara kusvika pamaminitsi makumi matatu seyadhi-yenguva imwe chete. Usati wagamuchira yako idecabtagene vicleucel dose, chiremba wako kana mukoti achapa imwe chemotherapy mishonga kugadzirira muviri wako idecabtagene vicleucel.

Pamberi peiyo dose ye idecabtagene vicleucel jekiseni rinofanira kupihwa, muyero wemasero ako machena eropa anozotorwa kuchitokisi chekuunganidza masero uchishandisa nzira inonzi leukapheresis (maitiro anobvisa machena masero eropa kubva mumuviri). Nekuti mushonga uyu unogadzirwa kubva kumaseru ako wega, unofanirwa kupihwa iwe chete. Izvo zvakakosha kuti uve nenguva uye kuti usarasikirwe yako yakarongedzwa maseru ekuunganidzwa kusarudzwa (s) kana kugamuchira yako yekurapa dosi. Iwe unofanirwa kuronga kugara mukati memaawa maviri enzvimbo kwawakagamuchira yako idecabtagene vicleucel kurapwa kweinenge mavhiki mana mushure medosi yako. Anopa hutano hwako anotarisa kuti aone kana kurapwa kwako kuri kushanda uye nekukutarisa iwe kune chero zvingangoitika mhedzisiro. Taura nachiremba wako nezvekuti ungagadzirira sei leukapheresis uye zvaunotarisira panguva uye mushure mekuita.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wagamuchira idecabtagene vicleucel jekiseni,

• udza chiremba wako uye wemishonga kana uri weergoria kune idecabtagene vicleucel, chero mimwe mishonga, dimethyl sulfoxide (DMSO), kana chero chimwe chezvinhu zvinosanganiswa mu idecabtagene vicleucel jekiseni. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: steroid senge dexamethasone, methylprednisolone (Medrol), prednisolone, uye prednisone (Rayos). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove nekuita kubva kumakemikari epamberi ekurapa senge matambudziko ekufema kana kusagadzikana kwemoyo. Uyezve, udza chiremba wako kana iwe wakambove nemapapu, itsvo, moyo, kana chirwere cheropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Iwe unozofanirwa kuve nepamuviri bvunzo usati watanga idecabtagene vicleucel. Kana iwe ukava nepamuviri uchigamuchira idecabtagene vicleucel, fonera chiremba wako nekukasira. Idecabtagene vicleucel inogona kukuvadza fetus.
• iwe unofanirwa kuziva kuti idecabtagene vicleucel jekiseni inogona kukuita iwe kukotsira uye kukonzeresa kuvhiringidzika, kushaya simba, dzungu, pfari, uye matambudziko ekubatanidza. Usatyaire mota kana kushandisa michina kweanokwana masvondo masere mushure meiyo idecabtagene vicleucel dose.
• usape ropa, nhengo, zvinyama, kana masero ekuisirwa mushure mekutambira yako idecabtagene vicleucel jekiseni.
• bvunza nachiremba wako kuti uone kana iwe uchida kugamuchira chero majekiseni. Hauna majekiseni pasina kutaura nachiremba wako kweanenge mavhiki matanhatu usati watanga chemotherapy, panguva yako idecabtagene vicleucel kurapwa, uye kusvikira chiremba wako akakuudza kuti immune system yako yapora.

Ukatadza nguva yekutora masero ako, unofanirwa kufonera chiremba wako nenzvimbo yekuunganidza ipapo ipapo. Ukasuwa musangano kuti ugamuchire yako idecabtagene vicleucel dose, unofanira kufonera chiremba wako ipapo ipapo.

Idecabtagene vicleucel inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kuvimbiswa
• kuonda
• kurasikirwa nenzara
• kurwadziwa mumuromo
• muromo wakaoma
• maziso akaoma

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• yakaderera weti kuwanda kana huwandu
• kuzvimba kwemaziso, kumeso, miromo, rurimi, huro, maoko, maoko, tsoka, makumbo, kana makumbo ezasi
• kunetseka kumedza
• mapundu
• mikoko
• kuvava

Idecabtagene vicleucel inogona kuwedzera njodzi yako yekuvandudza mamwe cancer. Taura nachiremba wako nezve njodzi dzekugamuchira uyu mushonga.

Idecabtagene vicleucel inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza zvese zvakagadzwa nachiremba wako, nzvimbo yekuunganidzira masero, uye rabhoritari. Chiremba wako anogona kuraira kumwe kuongorora kwerebhu kare, panguva, uye mushure mekurapwa kwako kuti utarise mhinduro yemuviri wako kune idecabtagene vicleucel jekiseni.

Usati waita chero bvunzo yerabhoritari, udza chiremba wako uye vashandi veirabhoritari kuti urikugamuchira idecabtagene vicleucel. Mushonga uyu unogona kukanganisa mhedzisiro yemamwe miedzo yemarabhoritari.

Kumbira wemishonga wako chero mibvunzo iwe unayo nezve idecabtagene vicleucel jekiseni.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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