Munyori: Janice Evans
Zuva Rekusika: 23 Chikunguru 2021
Gadziridza Zuva: 15 Mbudzi 2024
Anonim
Azathioprine - Pharmacology, mechanism of action, side effects,
Vhidhiyo: Azathioprine - Pharmacology, mechanism of action, side effects,

Zvemukati

Azathioprine inogona kuwedzera njodzi yako yekuvandudza mamwe marudzi ekenza, kunyanya kenza yeganda uye lymphoma (kenza inotanga mumasero anorwisa hutachiona). Kana iwe uine itsvo kuisirwa, panogona kuve nenjodzi yakakwira yekuti uchaita gomarara kunyangwe ukasatora azathioprine. Udza chiremba wako kana iwe wakambove nekenza uye kana iwe uri kutora kana wakambotora alkylating vamiririri senge chlorambucil (Leukeran), cyclophosphamide (Cytoxan), kana melphalan (Alkeran) yekenza. Kuti uderedze njodzi yekuti unozoita gomarara reganda, dzivisa kuratidzwa kwezuva kwenguva yakareba kana kuti zvisina basa uye kupfeka mbatya dzekudzivirira, magirazi ezuva, uye sunscreen. Udza chiremba wako nekukasira kana iwe ukaona chero shanduko muganda rako kana chero mapundu kana mashoma chero mumuviri wako.

Vamwe vechidiki uye vechidiki varume vakuru vakatora azathioprine vari voga kana nemumwe mushonga unonzi tumor necrosis factor (TNF) blocker yekurapa chirwere cheCrohn (mamiriro ezvinhu apo muviri unorwisa kumhara kwegwara rekugaya uchikonzera marwadzo, manyoka, kuonda, uye fever) kana ulcerative colitis (mamiriro anokonzera kuzvimba uye maronda mumutsara wekoloni [ura hukuru] uye rectum) yakagadzira hepatosplenic T-cell lymphoma (HSTCL). HSTCL mhando yakakomba yekenza inowanzo kukonzera kufa mukati menguva pfupi yenguva. Azathioprine haina kubvumidzwa neFood and Drug Administration (FDA) yekurapa chirwere cheCrohn kana ulcerative colitis, asi vanachiremba dzimwe nguva vanopa azathioprine kurapa aya mamiriro. Kana iwe ukagadzira chero cheizvi zviratidzo panguva yekurapwa kwako, dana chiremba wako nekukurumidza: kurwadziwa mudumbu; kupindwa nechando; kusanzwisisika kuonda; kudikitira usiku kana kupwanya kuri nyore kana kubuda ropa.


Azathioprine inogona kukonzera kuderera kwenhamba yemasero eropa mumapfupa ako, izvo zvinogona kukonzera zvakakomba kana kutyisidzira hupenyu hutachiona. Njodzi yekuti huwandu hwesero reropa rauinaro rinoderera zvakanyanya kana uine hutachiona (hwakagara nhaka) njodzi. Chiremba wako anogona kuraira bvunzo usati kana panguva yekurapa kwako kuti uone kana iwe uine iyi njodzi njodzi. Kutora mimwe mishonga kunogona zvakare kuwedzera njodzi yekuti masero ako eropa achaderera, saka udza chiremba wako kana uri kutora chero cheanotevera: , lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), Ramipril (Altace), kana trandolapril (Mavik); trimethoprim uye sulfamethoxazole (Bactrim, Septra); uye ribavirin (Copegus, Rebetol, Virazole). Kana ukasangana nechimwe chezviratidzo zvinotevera, dana chiremba wako nekukurumidza: kubuda ropa kusingawanzo kana kupwanya; kuneta zvakanyanya; ganda rakachenuruka; kurwadziwa nemusoro; kuvhiringidzika; dzungu; kukurumidza kurova kwemoyo; kunetseka kurara; kushaya simba; mweya wekufema; uye huro, fivha, kutonhora, uye zvimwe zviratidzo zvehutachiona. Chiremba wako acharaira bvunzo kare, panguva, uye mushure mekurapa kwako kuti uone kana masero ako eropa akanganiswa nemishonga iyi.


Taura nachiremba wako nezve njodzi dzekutora mushonga uyu.

Azathioprine inoshandiswa nemimwe mishonga kudzivirira kuisirwa kurambidzwa (kurwisa kwechikamu chakasimwa nema immune system) muvanhu vakagamuchira kuisirwa itsvo. Iyo inoshandiswawo kurapa rakakomba rheumatoid arthritis (mamiriro umo muviri unorwisa majoini ayo pachawo, zvichikonzera kurwadziwa, kuzvimba, uye kurasikirwa nebasa) apo mimwe mishonga nemishonga zvisina kubatsira. Azathioprine iri mukirasi yemishonga inonzi immunosuppressants. Inoshanda nekuderedza mashandiro edziviriro yemuviri kuitira kuti irege kurwisa nhengo yakaiswa kana majoini.

Azathioprine inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kamwe kana kaviri pazuva mushure mekudya. Tora azathioprine kwakatenderedza nguva imwechete (ma) mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora azathioprine chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Kana iwe uri kutora azathioprine kurapa rheumatoid arthritis, chiremba wako anogona kukutanga iwe pane yakaderera dosi uye zvishoma nezvishoma wedzera yako dosi mushure memasvondo matanhatu kusvika matanhatu uye kwete kanopfuura kamwe kamwe vhiki ina. Chiremba wako anogona kudzikira zvishoma nezvishoma dhizaini yako kana mamiriro ako achidzorwa. Kana iwe uri kutora azathioprine kudzivirira itsvo kupinza kurambwa, chiremba wako anogona kukutanga iwe pane yakakwira dosi uye udzikise muyero wako zvishoma nezvishoma sezvo muviri wako unogadzirisa kune iyo yekuisa.

Azathioprine inodzora rheumatoid arthritis asi hairape. Zvinogona kutora kusvika kumavhiki gumi nemaviri usati wanzwa kubatsirwa zvizere kweazathioprine. Azathioprine inodzivirira kuiswa kwekuramba chete chero bedzi iwe uri kutora mushonga. Ramba uchitora azathioprine kunyangwe iwe uchinzwa zvakanaka. Usarega kutora azathioprine usina kutaura nachiremba wako.

Azathioprine inoshandiswawo kurapa ulcerative colitis (chirwere chinokonzera kuzvimba uye maronda mumutsara wekoloni [ura hukuru] uye rectum) uye chirwere cheCrohn. Taura nachiremba wako nezve njodzi dzinogona kuitika dzekushandisa mushonga uyu kune ako mamiriro.

Mushonga uyu dzimwe nguva unonyorerwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora azathioprine,

  • udza chiremba wako uye wemishonga kana uri weergoria kune azathioprine, chero mimwe mishonga, kana chero chinhu chinowanikwa mumapiritsi eazathioprine. Kumbira chiremba wako kana wemishonga kuti uwane mazita ezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakataurwa muchikamu CHINOKOSHA CHENYENZO uye chero ipi inotevera: allopurinol (Zyloprim); aminosalicylates senge mesalamine (Apriso, Asacol, Pentasa, vamwe), olsalazine (Dipentum), uye sulfasalazine (Azulfidine); uye anticoagulants ('blood thinner') senge warfarin (Coumadin). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana uine chero hutachiona, kana iwe uine kana wakambove nechirwere cheitsvo.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Iwe unofanirwa kushandisa kuberekwa kuti uve nechokwadi chekuti iwe kana mumwe wako hauzove nemimba iwe uchinwa mushonga uyu. Fonera chiremba wako kana iwe kana mumwe wako mukava nepamuviri paunenge uchitora azathioprine. Azathioprine inogona kukuvadza fetus.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora azathioprine.
  • hauna majekiseni panguva kana mushure mekurapa kwako pasina kutaura nachiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Azathioprine inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kusvotwa
  • kurutsa
  • manyoka

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, danaidza chiremba wako nekukasira.

  • mapundu
  • kupindwa nechando
  • kushaya simba
  • kurwadziwa kwemhasuru

Mushonga uyu unogona kukonzera mimwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika iwe paunenge uchitora azathioprine.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • kusvotwa
  • kurutsa
  • manyoka
  • huro, fivha, kutonhora, uye zvimwe zviratidzo zvehutachiona

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Azasan®
  • Imuran®
Yekupedzisira Yakagadziridzwa - 04/15/2019

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