Munyori: Clyde Lopez
Zuva Rekusika: 17 Chikunguru 2021
Gadziridza Zuva: 18 Mbudzi 2024
Anonim
Sargramostim and ICIs: combinatorial therapeutic studies in metastatic melanoma – video abstract
Vhidhiyo: Sargramostim and ICIs: combinatorial therapeutic studies in metastatic melanoma – video abstract

Zvemukati

Sargramostin inoshandiswa kudzikisa mukana wehutachiona muvanhu vane acute myelogenous leukemia (AML; rudzi rwecancer yemasero machena eropa) uye vari kugamuchira chemotherapy mishonga iyo inogona kudzikisa huwandu hweeutrophils (rudzi rweropa sero rinodiwa kurwa hutachiona). Sargramostin inoshandiswawo muvanhu vari kuwedzerwa ropa masero, mune vanhu vari kuiswa mapfupa, uye kugadzirira ropa releukapheresis (kurapwa uko mamwe masero eropa anobviswa mumuviri ozodzokera mumuviri uchitevera. chemotherapy). Sargramostim inoshandiswawo muvanhu vasina kupindura mushure mekugamuchira kuwedzerwa kweropa. Sargramostin iri mukirasi yemishonga inonzi koloni-inosimudzira zvinhu. Inoshanda nekubatsira muviri kuti uwedzere neutrophils uye mamwe masero eropa.

Sargramostim inouya semhinduro (mvura) kana hupfu hunosanganiswa nemvura kuti ujekese subcutaneously (pasi peganda) kana kupinda mukati (mutsinga). Inoiswa (kujowa zvishoma nezvishoma) kwenguva inosvika maawa maviri kusvika makumi maviri nemana kamwe pazuva. Iyo zvakare inogona kuiswa jekiseni subcutaneously kamwe chete zuva nezuva. Kureba kwekurapa kwako kunoenderana nemamiriro aunayo uye nemuviri wako kupindura kumushonga.


Kana iwe uri kushandisa sargramostim kudzikisira njodzi yehutachiona panguva yekemotherapy, iwe unozogamuchira mishonga kanokwana kana mazuva mushure mekugashira yako yekupedzisira dosi yeyese chemotherapy kutenderera Iwe ucharamba uchigamuchira mishonga zuva rega rega kusvikira yako masero eropa kuverenga kuverenga kune zvakajairwa kana kweanosvika mavhiki matanhatu. Kana iwe uri kushandisa sargramostim kugadzirira ropa rako releukapheresis, unozogamuchira mushonga kamwe zuva nezuva kusvika kune leukapheresis yekupedzisira. Kana iwe urikushandisa sargramostim nekuti urikuitwa ropa reropa rekumisikidza maseru, unozogashira mushonga kutanga pazuva rekuiswa kweropa uye woenderera kwemazuva matatu. Kana iwe uri kushandisa sargramostim kudzikisa njodzi yekutapukirwa panguva yekudyiwa kwemongo wepfupa, unozogamuchira mishonga kanenge maawa makumi maviri nemana mushure mekugamuchira chemotherapy uyezve maawa maviri kusvika mana mushure mekupfupa kwemongo. Kana iwe uri kushandisa sargramostim nekuti hausi kupindura kune pfupa rekutsvaira, unozogamuchira mushonga kamwe pazuva pazuva kwemazuva gumi nemana. Usarega kushandisa sargramostim usina kutaura nachiremba wako.


Sargramostim inogona kupihwa iwe nemukoti kana mumwe mupi wezvehutano, kana iwe unogona kuudzwa kuti jekiseni mishonga kumba. Kana iwe uchizove jekiseni sargramostim, jekiseni mishonga yacho panguva yakafanana mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Shandisa sargramostim chaizvo sekurairwa. Usashandise zvishoma kana zvishoma kana kuishandisa kakawanda kupfuura zvakatemwa nachiremba wako.

Kana iwe uchizove jekiseni sargramostim iwe pachako, mupi wezvehutano anokuratidza maitiro jekiseni mushonga. Iva nechokwadi chekuti unonzwisisa mafambiro aya. Kumbira mupiki wako wezvehutano kana iwe uine chero mibvunzo nezve kuti pane muviri wako unofanirwa kubaya sargramostim, nzira yekupa jekiseni, rudzii rwejekiseni raunoshandisa, kana maitiro ekurasa tsono dzakashandiswa uye majekiseni mushure mekupinza mushonga.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Sargramostim zvakare dzimwe nguva inoshandiswa kurapa mamwe marudzi emyelodysplastic syndrome (boka remamiriro ezvinhu umo mwongo wemapfupa unoburitsa masero eropa ayo ari misshapen uye asingaburitse yakakwana masero eropa ane hutano) uye aplastic anemia (mamiriro umo mwongo wepfupa usingaiti. gadzira masero matsva eropa). Sargramostim zvakare dzimwe nguva inoshandiswa kudzikisa mukana wehutachiona muvanhu vane hutachiona hwehutachiona hwehutachiona hweHIV. Taura nachiremba wako nezve njodzi dzekushandisa mushonga uyu kune ako mamiriro.


Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati washandisa jekiseni yesargramostim,

  • udza chiremba wako uye wemishonga kana uri weergoria kune sargramostim, mbiriso, chero mimwe mishonga, kana chero chinhu chinogadzirwa nesargramostim jekiseni. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura betamethasone (Celestone), dexamethasone (Decadron), lithium (Lithobid), methylprednisolone (Medrol), uye prednisone.Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana iwe uri kurapwa kana iwe wakamborapwa ne radiation radiation kana kana iwe kana wakambove nekenza, edema (kuzvimba kwemudumbu, tsoka, makumbo, kana makumbo ezasi), chero rudzi rwechirwere chemoyo, moyo kutadza. , kurova kwemoyo zvisina kujairika, mapapu, itsvo, kana chirwere chechiropa.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri iwe uchishandisa sargramostim, fonera chiremba wako.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikushandisa sargramostim.
  • iwe unofanirwa kuziva kuti sargramostim inoderedza njodzi yehutachiona, asi haidziviriri hutachiona hwese hunogona kukura panguva kana mushure memakemikari. Fonera chiremba wako nekukasira kana iwe ukava nezviratidzo zvehutachiona senge fivhiri, kutonhora, huro, kana kukosora kuri kuenderera uye kuzara.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Sargramostim inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kutsvuka, kuzvimba, kupwanya, kuruma kana bundu munzvimbo yaibayiwa mishonga
  • pfupa, kubatana, kana kurwadziwa kwemhasuru
  • musoro
  • kusvotwa
  • kurutsa
  • manyoka
  • kurwadziwa nemudumbu
  • maronda emuromo
  • kurasikirwa nenzara
  • kurasikirwa nevhudzi

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • kutadza kufema kana kukurumidza kufema
  • kunetseka kufema
  • kurira
  • dzungu
  • vangadikitira
  • mikoko
  • mapundu
  • kuvava
  • kuzvimba kwakatenderedza muromo, kumeso, maziso, dumbu, tsoka, makumbo, kana makumbo ezasi
  • kamwe kamwe kuwedzera uremu
  • kurwadziwa pachipfuva
  • nekukurumidza kana zvisina kujairika kurova kwemoyo
  • kufenda
  • kupwanya kusingawanzo kana kupenda kwepepuru pasi peganda
  • kubuda ropa zvisina kujairika
  • mhino dzemhino
  • kuneta zvisina kujairika kana kushaya simba
  • kuderera kwekuita weti

Sargramostim inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza mushonga uyu mumudziyo wawakauya nawo, kure nechiedza chezuva, chakavharwa, uye pasingasvikike nevana. Chengetedza sargramostim mufiriji. Usaisa chando kana kuzunza sargramostim. Akavhura sargramostim magaba anogona kuiswa mufiriji kwemazuva anosvika makumi maviri. Rasa ndiro dzakavhurwa mushure memazuva makumi maviri.

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • mweya wekufema
  • kuneta zvisina kujairika kana kushaya simba
  • kupindwa nechando
  • nekukurumidza kana zvisina kujairika kurova kwemoyo
  • kusvotwa
  • musoro
  • mapundu

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune sargramostim.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Leukine®
  • Granulocyte-Macrophage Colony-Inokurudzira Chinhu
  • GM-CSF
Yakagadziridzwa Yakagadziridzwa - 11/15/2016

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