Alpha-Fetoprotein (AFP) Bvunzo
Zvemukati
- Chii chinonzi alpha-fetoprotein (AFP) bvunzo?
- Chii chinoshandiswa?
- Sei ndichida bvunzo yeAFP?
- Chii chinoitika panguva yekuedzwa kweAFP?
- Ndichafanira here kuita chero chinhu kugadzirira bvunzo?
- Pane here njodzi kune bvunzo?
- Zvinorevei mhedzisiro yacho?
- Pane chimwe chinhu here chandinofanira kuziva nezve AFP bvunzo?
- Zvinyorwa
Chii chinonzi alpha-fetoprotein (AFP) bvunzo?
Alpha-fetoprotein (AFP) ipuroteni inogadzirwa muchiropa chemucheche ari kukura. Munguva yekukura kwechecheche, imwe AFP inopfuura nepakati peplacenta uye muropa raamai. Chiyero cheAFP chinoyera huwandu hweAFP mune vakadzi vane nhumbu panguva yechipiri trimester yepamuviri. Kunyanyisa kana kushoma AFP muropa raamai kunogona kuva chiratidzo chekuremara kwekuberekwa kana imwe mamiriro. Izvi zvinosanganisira:
- Iyo neural tube kuremara, chakakomba mamiriro chinokonzeresa zvisina kujairika kukura kweanokura huropi hwemwana uye / kana musana
- Down syndrome, chirwere chinokonzerwa nehutachiona chinokonzera kuremara kwepfungwa uye kunonoka kukura
- Mapatya kana kuberekwa kwakawanda, nekuti anopfuura mwana mumwe chete ari kuburitsa AFP
- Kusarongeka kwezuva rakakodzera, nekuti matanho eAFP anochinja panguva yepamuviri
Mamwe mazita: AFP Maternal; Maternal Serum AFP; msAFP skrini
Chii chinoshandiswa?
Kuongororwa kweropa kweAFP kunoshandiswa kuongorora mwana ari mudumbu kuti azive njodzi yekuzvarwa nekuremara, sekunge neural tube defects kana Down syndrome.
Sei ndichida bvunzo yeAFP?
IAmerican Pregnancy Association inoti vakadzi vese vane nhumbu vanofanirwa kupihwa bvunzo yeAFP imwe nguva pakati pegumi nemashanu kusvika makumi maviri vhiki yekuzvitakura. Muedzo unogona kunyanya kukurudzirwa kana iwe:
- Iva nenhoroondo yemhuri yekuremara kwekuzvarwa
- Vane makore makumi matatu nemashanu kana kupfuura
- Iva nechirwere cheshuga
Chii chinoitika panguva yekuedzwa kweAFP?
Nyanzvi yezvehutano inotora muyero weropa kubva mutsinga iri muruoko rwako, uchishandisa tsono diki. Mushure mekunge tsono yaiswa, kashoma reropa kanounganidzwa muthubhu yekuyedza kana muhombodo. Unogona kunzwa kakuruma kana tsono ichipinda kana kubuda. Izvi zvinowanzotora maminetsi asingasviki mashanu.
Ndichafanira here kuita chero chinhu kugadzirira bvunzo?
Iwe haudi chero yakakosha gadziriro yeiyo AFP bvunzo.
Pane here njodzi kune bvunzo?
Pane njodzi shoma kwauri kana kumwana wako ane AFP kuongororwa ropa. Unogona kunge uine marwadzo mashoma kana kupwanya panzvimbo yakaiswa tsono, asi zviratidzo zvizhinji zvinokurumidza kupera. Imwe bvunzo inonzi amniocenteis inopa yakanyanya kuongororwa kuongororwa kwe Down syndrome uye zvimwe hurema hwekuzvarwa, asi bvunzo ine njodzi diki yekukonzera kusununguka.
Zvinorevei mhedzisiro yacho?
Kana zvawanikwa zvikaratidza kukwirira kupfuura zvakajairwa AFP mazinga, zvinogona kureva kuti mwana wako ane neural chubhu hurema senge spina bifida, mamiriro umo mapfupa emuzongoza asingavhare akatenderedza musana, kana anencephaly, mamiriro ayo uropi hahukure zvakanaka.
Kana zviwanikwa zvako zvichiratidza zvakaderera pane zvakajairwa AFP mazinga, zvinogona kureva kuti mwana wako ane hutachiona kusagadzikana senge Down syndrome, mamiriro anokonzeresa njere uye budiriro.
Kana yako AFP mazinga asiri echinyakare, hazvireve hazvo kuti pane dambudziko nemwana wako. Zvinogona kureva kuti urikupa vana vanopfuura mumwe chete kana kuti zuva rako rekukanganisa harina kunaka. Iwe unogona zvakare kuwana manyepo-akanaka mhedzisiro. Izvi zvinoreva kuti mhedzisiro yako inoratidza dambudziko, asi mwana wako ane hutano. Kana zviwanikwa zvako zvichiratidza yakakwira kana yakaderera pane yakajairwa nhanho yeAFP, ungangowana mimwe miedzo yekubatsira kuongorora.
Dzidza zvakawanda nezve bvunzo dzemarabhoritari, mareferenzi masosi, uye mhinduro dzekunzwisisa
Pane chimwe chinhu here chandinofanira kuziva nezve AFP bvunzo?
Ongororo yeAFP inowanzo kuve chikamu cheyakawanda yeedzo dzepamberi yekuberekwa inonzi multiple marker kana katatu screen screen. Mukuwedzera kune AFP, kuongorora kwechikwata chetatu kunosanganisira kuongororwa kweHCG, hormone inogadzirwa ne placenta, uye estriol, fomu yeestrogen inogadzirwa nemucheche. Aya maedzo anogona kubatsira kuongorora Down syndrome uye zvimwe zvinokanganisa magene.
Kana iwe uri panjodzi yakanyanya yekuve nemwana ane zvimwe zvakasununguka kuberekwa, mupi wako anogona zvakare kukurudzira bvunzo nyowani inonzi isina-isina DNA (cfDNA). Uku ndiko kuongororwa kweropa kunogona kupihwa kutanga senge gumith vhiki yekuzvitakura. Iyo inogona kuratidza inogona kuratidza kana mwana wako ane mukana wakakwirira wekuve neDown syndrome kana zvimwe zvinetso zvemagene.
Zvinyorwa
- American Pregnancy Sangano [Internet]. Irving (TX): American Kubata Pamuviri Association; c2017. Maternal Serum Alpha-Fetoprotein Screening (MSAFP) [yakagadziridzwa 2016 Sep 2; yakataurwa 2017 Jun 5]; [angangoita matatu skrini. Inowanikwa kubva ku: http://americanpregnancy.org/prenatal-testing/maternal-serum-alpha-fetoprotein-screening
- American Pregnancy Sangano [Internet]. Irving (TX): American Kubata Pamuviri Association; c2017. Triple Screen Bvunzo [yakagadziridzwa 2016 Sep 2; yakataurwa 2017 Jun 5]; [angangoita matatu skrini. Inowanikwa kubva ku: http://americanpregnancy.org/prenatal-testing/triple-screen-test/
- Makuva JC, Miller KE, Vatengesi AD. Maternal Serum Katatu Kuongorora Kuongorora muPamuviri. Ndiri Chiremba weNzara [Internet]. 2002 Mar 1 [yataurwa 2017 Jun 5]; 65 (5): 915–921. Inowanikwa kubva: https://www.aafp.org/afp/2002/0301/p915.html
- Johns Hopkins Mushonga [Internet]. Johns Hopkins Mushonga; Hutano Raibhurari: Kwakajairika Kuyedzwa Panguva Yepamuviri [yakataurwa 2017 Jun 5]; [angangoita matatu skrini. Inowanikwa kubva: http://www.hopkinsmedicine.org/healthlibrary/conditions/adult/pregnancy_and_childbirth/common_test_during_pregnancy_85,p01241
- Lab Kuedza Pamhepo [Internet]. Washington DC: American Association yeKiriniki Chemistry; c2001–2019. Maternal Serum Kuongorora, Yechipiri Trimester; [yakagadziridzwa 2019 Chivabvu 6; yakataurwa 2019 Jun 4]; [angangoita maviri skrini. Inowanikwa kubva: https://labtestsonline.org/tests/maternal-serum-screening-second-trimester
- Lab Kuedza Pamhepo [Internet]. American Association yeKiriniki Chemistry; c2001–2017. Glossary: Spina Bifida [yataurwa 2017 Jun 5]; [angangoita matatu skrini. Inowanikwa kubva: https://labtestsonline.org/glossary/spina-bifida
- Merck Chinyorwa Chevatengi Vhezheni [Internet]. Kenilworth (NJ): Merck & Co Inc. .; c2017. Kuongorora Prenatal Kuongorora [yakagadziridzwa 2017 Jun; yakataurwa 2019 June 4]; [angangoita matatu skrini. Inowanikwa kubva ku: http://www.merckmanuals.com/home/women-s-health-issues/detection-of-genetic-disorders/prenatal-diagnostic-testing
- National Center Yekufambira Mberi Dudziro Sayenzi / Genetic uye Rare Zvirwere Ruzivo Ruzivo [Internet]. Gaithersburg (MD): Dhipatimendi reUtano reU.S. Neural Tube Kukanganisa [yakagadziridzwa 2013 Mbudzi 6; yakataurwa 2017 Jun 5]; [angangoita matatu skrini. Inowanikwa kubva ku: https://rarediseases.info.nih.gov/diseases/4016/neural-tube-defects
- National Mwoyo, Mapapu, uye Ropa Institute [Internet]. Bethesda (MD): Dhipatimendi reUtano reU.S. Ndezvipi Njodzi dzekuedzwa kweropa? [yakagadziridzwa 2012 Jan 6; yakataurwa 2017 Jun 5]; [angangoita mashanu skrini. Inowanikwa kubva: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
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- Yunivhesiti yeRochester Medical Center [Internet]. Rochester (NY): Yunivhesiti yeRochester Medical Center; c2017. Health Encyclopedia: Alpha-fetoprotein (AFP) [yataurwa 2017 Jun 5]; [angangoita maviri skrini. Inowanikwa kubva: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid;=P02426
- Yunivhesiti yeRochester Medical Center [Internet]. Rochester (NY): Yunivhesiti yeRochester Medical Center; c2017. Health Encyclopedia: Alpha-fetoprotein (Ropa) [yataurwa 2017 Jun 5]; [angangoita maviri skrini. Inowanika kubva: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=alpha_fetoprotein_maternal_blood
- UW Hutano [Internet]. Madison (WI): Yunivhesiti yeWisconsin Zvipatara uye Makiriniki Chiremera; c2017. Ruzivo rwehutano: Alpha-Fetoprotein (AFP) muRopa [yakagadziridzwa 2016 Jun 30; yakataurwa 2017 Jun 5]; [angangoita mashanu skrini. Inowanikwa kubva: https://www.uwhealth.org/health/topic/medicaltest/alpha-fetoprotein-afp-in-blood/hw1663.html
- UW Hutano [Internet]. Madison (WI): Yunivhesiti yeWisconsin Zvipatara uye Makiriniki Chiremera; c2017. Ruzivo rwehutano: Katatu kana Quad Kuongororwa kweKutadza Kuberekwa [yakagadziridzwa 2016 Jun 30; yakataurwa 2017 Jun 5]; [angangoita mashanu skrini. Inowanikwa kubva: https://www.uwhealth.org/health/topic/special/maternal-serum-triple-or-quadruple-screening-test/ta7038.html#ta7038-sec
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