Kudzidza Kunowana Dambudziko Rakakura neIye-Kumba Mageneti Ekuyedza

Zvemukati

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Direct-kune-mutengi (DTC) kuongororwa kwemajini kuve nekanguva. 23andMe achangowana FDA mvumo yekuyedza shanduko ye BRCA, zvinoreva kuti kekutanga, ruzhinji rwevanhu runogona kuzviongorora kumwe kushanduka kunozivikanwa kunowedzera mukana wecancer yemazamu, ovari uye yeprostate. Chinhu ndechekuti, nyanzvi dzemageneti dzakagara dzichinyevera kuti bvunzo dzepamba dzine zvadzinogumira uye dzinogona kunge dzisina kunyatsoita sekuonekwa kwadzo. (BTW, 23andMe inongova imwe yemakambani akati wandei anopa kuongororwa kwecancer yemazamu kumba-kunyangwe iriyo yega isingatsvage mushonga wechiremba.)

Zvino, kutsva kutsva kunovhenekera chaizvo sei zvisina kukodzera bvunzo dzepamba dzingave. Chidzidzo chitsva mumagazini Genetics muMushonga vakatarisa makumi masere nemapfumbamwe evarwere anga atumirwa kukiriniki inotungamira yegenetics lab, Ambry Genetics, kuti iongororwe kaviri mushure mekuedzwa kwekumba kwainge kwaitwa kare. Iyi tsika, inonzi "yekusimbisa kuyedza," inowanzo kurudzirwa nevarapi vezvehutano kana mumwe munhu akagamuchira mhedzisiro yavo kubva ku-kumba-genet test. Kazhinji, kusimbiswa kwekuedzwa kunokumbirwa nachiremba wekutanga wekuchengeta mushure mekunge murwere abvunza rubatsiro kududzira yavo yakasviba data mushumo.

Iri "raw" data rinowanzoda kududzirwa nevechitatu-bato lab kuti risimbiswe uye rinzwisiswe nemazvo - nhanho iyo vanhu vazhinji vanosvetuka. Muchidzidzo ichi, vatsvakurudzi vakaunganidza zvikumbiro zvekuongorora zvekusimbisa sezvavaigona kuwana uye vakaenzanisa kuongorora kwavo kweDNA yevarwere kune zvakataurwa nemigumisiro yekuongorora kumba. Zvinoratidza kuti 40 muzana yezvakasiyana (kureva, iwo chaiwo majini) akashumwa mune data kubva kumba-kumba bvunzo aive enhema.

Chaizvoizvo, izvo zvinoreva kuti magene anosiyanisa bvunzo dzekumba dzakaonekwa mune mbishi data-ese ari pasi-panjodzi uye ane njodzi huru-haana kusimbiswa nekiriniki genetics lab. Zvakare, mamwe emhando dzakasiyana dzemageneti anozivikanwa se "kuwedzera njodzi" mageneti nekuyedzwa-kumba akaverengerwa se "benign" nekiriniki lab. Izvi zvinoreva kuti vamwe vevanhu vakagamuchira mibairo "yakanaka" kubva pabvunzo dzavo vaive * kwete * chaizvo panjodzi yakawedzera. (Zvakabatana: Kumba-Kumba Kuongororwa Kwekurapa Kunobatsira Here Kana Kukukuvadza?)

Vanachipangamazano vemajini havashamiswe."Ndiri kufara kuti nhamba dziri kuratidza huwandu hwepamusoro hwekuverenga zvisiri izvo kuitira kuti vatengi vakawanda vazive kusasimba kweiyo DTC genetic test," anodaro Tinamarie Bauman, mukoti-akasimbiswa epamusoro genetic mukoti uye mubatsiri director wepamusoro-. njodzi genetics chirongwa kuAMITA Health Cancer Institute.

Mhinduro yacho: Taura nachiremba wako nezvekuona munhu anopa mazano. "Genetic mazano vanoita zvinopfuura kungoongorora njodzi; vanokubatsira kuti unzwisise zvakawanda nezve mhedzisiro yakanaka kana yakaipa," Bauman anodaro. "Chero ani anotora bvunzo yeDTC obva agamuchira mhedzisiro mhedzisiro anogona kutaura nekatarisa kuti pane zvakawanda zvinofanirwa kuongororwa uye kududzirwa."

Kana iwe uchinyatso kuva nenjodzi yakawedzera yehosha yekugara nhaka, chipangamazano wezvechibereko anogona kukubatsira kutora matanho ekuti ubvise njodzi yako, uiongorore pakutanga, kana kupa kurapwa kwakanyatsozivikanwa uye kwehukama kana zvichidikanwa.

Uye kunyangwe zano raBauman kune vatengi nezve bvunzo dzeDTC raive rakafanana chidzidzo ichi chisati chabuda, iko zvino chave kunzwa kutonyanya kukurumidzira-kunyanya kune avo vanogona kunge vaine hutachiona hwecancer. “Ini ndinoshanda muoncology, uye ndinoshushikana zvikuru nekuongororwa kwegomarara kumba,” anodaro. "Pane mukana wakakura wekugona kuchinja hupenyu-manyepo uye zvisizvo."

Saka kana iwe wakatowana mhinduro kubva ku-kumba genetic test, kuwana yekusimbisa bvunzo kwakakosha, anodaro. "Zvakakosha kusimbisa ese maDTC akachinjika data musiyano murabhoritari ine ruzivo," Bauman anoti. Izvo zvakakoshawo kuti unzwisise zvakanakira uye zvisingakwanisike zvemuyedzo, uye mhedzisiro inogona kuitika yemhedzisiro. Iwe uchaitei kana mhedzisiro ikadzoka yakanaka? Zvinorevei kana zvisina kunaka? "Mvumo ine ruzivo chikamu chakakosha chemuitiro," Bauman anodaro. "Kubvunza kunogona kubvisa nyonganiso."

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