Bvunza iyo Nyanzvi: Kunzwisisa Mamiriro Enyika yeMishonga yeAnkylosing Spondylitis

Zvemukati

• Ankylosing spondylitis inogona kurapwa here?
• Ndeapi marapirwo anovimbisa zvikuru mumakiriniki ekuedzwa?
• Ndinoziva sei kuti ndinokodzera kutongwa nekiriniki?
• Ndeapi marapirwo matsva e ankylosing spondylitis?
• Ndedzipi nzira dzekurapa dzaunokurudzira? Ndeapi maekisesaizi aunokurudzira?
• Kuvhiya sarudzo here yekurapa ankylosing spondylitis?
• Iwe unoona sei kurapwa kweankylosing spondylitis ichichinja pamusoro pemakore gumi anotevera?
• Iwe unofunga chii chinotevera chiitiko chekurapa ankylosing spondylitis chichava?
• Tekinoroji yazvino inobatsira sei kumberi kurapwa?

Ankylosing spondylitis inogona kurapwa here?

Parizvino, hapana mushonga we ankylosing spondylitis (AS). Zvisinei, vazhinji varwere vane AS vanogona kutungamira hupenyu hurefu, hune zvibereko.

Nekuda kwenguva iri pakati pekutanga kwezviratidzo nekusimbiswa kwechirwere, kutanga kuongororwa kunokosha.

Kurapa manejimendi, anobatsira ekurapa ekurapa, uye zvakanangwa zvekurovedza muviri zvinogona kupa varwere kuvandudza hupenyu hwehupenyu. Mhedzisiro mhedzisiro inosanganisira zororo rekurwadziwa, yakawedzera mhando yekufamba, uye kuwedzera kugona kweanoshanda.

Ndeapi marapirwo anovimbisa zvikuru mumakiriniki ekuedzwa?

Iwo anovimbisa zvikuru emakiriniki miedzo ndeavo vanoongorora kushanda pamwe nekuchengeteka kwebimekizumab. Icho chinodhaka chinodzivirira zvese zviri zviviri interleukin (IL) -17A uye IL-17F - mapuroteni madiki anobatsira kuzviratidzo zveAS.

Filgotinib (FIL) inosarudza inhibitor yaJanus kinase 1 (JAK1), imwe protein inonetsa. FIL parizvino iri kusimudzira kurapwa kwe psoriasis, psoriatic arthritis, uye AS. Inotorwa nemuromo uye ine simba kwazvo.

Ndinoziva sei kuti ndinokodzera kutongwa nekiriniki?

Kukodzera kwako kutora chikamu mumuedzo wekiriniki weAS kunoenderana nechinangwa chekuyedza.

Miedzo inogona kudzidza kushanda pamwe nekuchengetedzwa kwemishonga yekutsvagisa, kufambira mberi kwekubatana kwemabhonzo, kana nzira yechisikigo yechirwere. Kugadziriswa kweiyo yekuongororwa nzira yeAS kunokanganisa magadzirirwo emakiriniki miedzo mune ramangwana.

Ndeapi marapirwo matsva e ankylosing spondylitis?

Dzazvino FDA inotenderwa mishonga yekurapwa kweAS ndeiyi:

• ustekinumab (Stelara), IL12 / 23 inhibitor
• tofacitinib (Xeljanz), iyo JAK inhibitor
• secukinumab (Cosentyx), IL-17 inhibitor uye yakasarudzika monoclonal antibody
• ixekizumab (Taltz), IL-17 inhibitor

Ndedzipi nzira dzekurapa dzaunokurudzira? Ndeapi maekisesaizi aunokurudzira?

Mishonga yekurapa yandinogarokurudzira inosanganisira:

• kukwiza muviri
• acupuncture
• acupressure
• hydrotherapy maitiro

Zvakananga kurovedza muviri zvinosanganisira:

• kutambanudza
• vakagara madziro
• mapuranga
• chirebvu chinopinda mune chinodzokorodza chinzvimbo
• hudyu kutambanudza
• kufema kwakadzika kurovedza muviri uye kufamba

Iko kushandiswa kweiyo yoga matekiniki uye transcutaneous emagetsi nerve kukurudzira (TENS) zvikamu zvinokurudzirwa zvakare.

Kuvhiya sarudzo here yekurapa ankylosing spondylitis?

Kuvhiya hakuwanzo muAS. Dzimwe nguva, chirwere ichi chinofambira mberi kusvika pakukanganisa zviitiko zvezuva nezuva nekuda kwekurwadziwa, kutadza kwekufamba, uye kushaya simba. Mune zviitiko izvi, kuvhiyiwa kunogona kukurudzirwa.

Kune akatiwandei maitiro anogona kudzikamisa marwadzo, kudzikamisa musana, kugadzirisa mamiriro, uye kudzivirira kusagadzikana kwetsinga. Spinal fusion, osteotomies, uye laminectomies inoitwa navanachiremba vane hunyanzvi inogona kubatsira kune vamwe varwere.

Iwe unoona sei kurapwa kweankylosing spondylitis ichichinja pamusoro pemakore gumi anotevera?

Iko kufungidzira kwangu kuti marapirwo anozoenderana zvichienderana neakasiyana maratidziro emakiriniki, akavandudzwa ekufungidzira matekinoroji, uye chero zvakabatanidzwa kutaura kwechirwere ichi.

AS inowira pasi pemuraira wechikamu chakapamhama chehosha dzinonzi spondyloarthropathies. Izvi zvinosanganisira psoriasis, psoriatic arthritis, chirwere chinoputira ura, uye inoshanda spondyloarthropathy.

Panogona kuve necrossover mharidzo yeaya maseteti uye vanhu vanozobatsirwa nenzira yakanangwa yekurapa.

Iwe unofunga chii chinotevera chiitiko chekurapa ankylosing spondylitis chichava?

Maviri chaiwo majini, HLA-B27 uye ERAP1, inogona kuve inobatanidzwa mukutaura kweAS. Ini ndinofunga chinotevera budiriro mukurapa kweAS kuchaziviswa nekunzwisisa maitiro avanoita uye kusangana kwavo nehutachiona hwechirwere.

Tekinoroji yazvino inobatsira sei kumberi kurapwa?

Kumwe kufambira mberi kukuru kuri muanomedicine. Iyi tekinoroji yakashandiswa kubata zvinobudirira zvimwe zvinokonzeresa hosha senge osteoarthritis uye rheumatoid arthritis. Iko kuvandudzwa kweanotechnology-based dhirivhari masystem inogona kunge iri inonakidza yekuwedzera kune manejimendi eAS.

Brenda B. Spriggs, MD, FACP, MPH, ndiye Clinical Professor Emerita, UCSF, Rheumatology, chipangamazano kumasangano akati wandei ekuchengetedza hutano, uye munyori. Zvaanofarira zvinosanganisira kutsigira nemoyo murefu uye kuda kwekupa nyanzvi rheumatology kubvunza kuvanachiremba uye nevanhu vasina kuchengetedzwa. Ndiye mubatanidzwa wemunyori we "Tarisa pane Yako Hutano Hutano: Nhungamiro Nhungamiro kune Hutano Kuchengetwa Kwaunokodzera."