Yepamberi Kenza Yemazamu Pamberi uye Pashure Pemwedzi

Zvemukati

• 1.Ndeupi mushonga wekutanga wehormone receptor-positive metastatic breast cancer?
• 2. Kenza yemazamu inorapwa sei mumadzimai epamberi pekuguma kuenda kumwedzi?
• 3. Ndeipi kurapwa kwakatemerwa vakadzi vanopera kuenda kumwedzi?
• 4. Ko chemotherapy kana yakanangwa yekurapa inoshandiswa kurapa metastatic kenza yemazamu?

Mhedziso

Metastatic breast cancer (inonziwo advanced cancer cancer) zvinoreva kuti cancer yakapararira kubva pazamu ichienda kune dzimwe nzvimbo mumuviri. Ichiri kutarisirwa sekenza yemazamu nekuti iyo metastases ine yakafanana mhando yekenza maseru.

Kurapa sarudzo kunoenderana nehunhu chaihwo hwebundu, senge iri hormone receptor-yakanaka uye kana iri HER2-yakanaka. Zvimwe zvinhu zvinosanganisira hutano hwazvino, chero kurapwa kwawakambogamuchira, uye zvakatora nguva yakareba sei kuti cancer irambe ichidzoka.

Kurapa kunoenderanawo nekuti kenza yakapararira zvakadii uye kana wapfuura nekumira kwemwedzi. Heano mimwe mibvunzo yekubvunza chiremba wako nezve epamberi kenza yemazamu sezvo ichienderana nekuenda kumwedzi.

1.Ndeupi mushonga wekutanga wehormone receptor-positive metastatic breast cancer?

Hormonal Therapy, kana endocrine Therapy, inowanzo kuve chikamu chekutanga chekurapa kwevakadzi vane hormone receptor-yakanaka metastatic kenza yemazamu. Iyo dzimwe nguva inonzi anti-hormone kurapwa nekuti inoita senge inopesana neyehomoni kutsiva kurapa (HRT).

Chinangwa ndechekuderedza iwo mazinga eestrogen uye progesterone mumuviri kuvhara aya mahormone kuti asvike kune cancer maseru uye kuwana iyo estrogen yavanoda kuti ikure.

Hormonal therapy inogona kushandiswa kukanganisa kukanganisa kwehomoni pane kukura kwemasero uye kushanda kwese. Kana mahormone akavharirwa kana kubviswa, masero ekenza kashoma kuti ararame.

Hormonal therapy inomisa zvakare maseru emazamu ane hutano kubva mukugamuchira mahormone ayo anogona kukurudzira maseru ane cancer kuti adzokere mukati mechipfuva kana kumwe kunhu.

2. Kenza yemazamu inorapwa sei mumadzimai epamberi pekuguma kuenda kumwedzi?

Metastatic kenza yemazamu kurapwa mune premenopausal vakadzi vane mahormone receptor-akanaka kenza anowanzo sanganisira ovarian kudzvinyirira. Maitiro aya anoderedza mahormone mumuviri kuti ubvise bundu reestrogen rinoda kukura.

Kudzvinyirira Ovarian kunogona kuwanikwa mune imwe yenzira mbiri:

• Zvinodhaka zvinogona kumisa mazai kubva mukugadzira estrogen, iyo inokonzeresa kuenda kumwedzi kwenguva yakati.
• Nzira yekuvhiya inonzi oophorectomy inogona kubvisa mazai uye kumisa kugadzirwa kweestrogen zvachose.

Iyo aromatase inhibitor inogona kupihwa mune premenopausal vakadzi pamwe chete neovarian kudzvinyirira. Aromatase inhibitors inogona kusanganisira:

• anastrozole (Arimidex)
• exemestane (Aromasin)
• letrozole (Femara)

Tamoxifen, antiestrogen, inowanzo shandiswa kurapa metastatic kenza yemazamu muvakadzi ve premenopausal. Inogona kudzivirira cancer kubva kudzoka kana kupararira kumwe kunhu.

Tamoxifen inogona kunge isiri sarudzo kana kenza ichifambira mberi panguva yekurapwa kwetamoxifen. Kubatanidza kudzvinyirira ovari uye tamoxifen kwawanikwa kunatsiridza kupona zvichienzaniswa netamoxifen yoga.

3. Ndeipi kurapwa kwakatemerwa vakadzi vanopera kuenda kumwedzi?

Kudzvinyirira Ovarian hakuna kudikanwa kune vakadzi vanotevera kuenda kumwedzi. Mazai avo akatomira kugadzira huwandu hwakawanda hweestrogen. Ivo vanongo gadzira shoma shoma mumafuta avo echipfuva uye adrenal gland.

Postmenopausal hormone therapy inowanzo sanganisira aromatase inhibitor. Iyi mishonga inoderedza huwandu hweestrogen mumuviri nekumisa matishu uye nhengo kunze kwemazai kubva mukugadzira estrogen.

Zvinowanzoitika mhedzisiro yearomatase inhibitors inosanganisira:

• kupisa kunopisa
• kusvotwa
• kurutsa
• mapfupa anorwadza kana majoini

Zvimwe zvakakomba mhedzisiro zvinosanganisira kuponda mapfupa uye kuwedzera kwecholesterol.

Vakadzi vePostmenopausal vanogona kupihwa tamoxifen kwemakore akati wandei, kazhinji mashanu kana kupfuura. Kana mushonga wacho uchishandiswa isingasviki makore mashanu, aromatase inhibitor kazhinji inogona kupihwa kwemakore asara.

Mimwe mishonga inogona kupihwa inosanganisira CDK4 / 6 inhibitors kana fulvestrant.

4. Ko chemotherapy kana yakanangwa yekurapa inoshandiswa kurapa metastatic kenza yemazamu?

Chemotherapy ndiyo yakakosha yekurapa sarudzo yekenza dzemazamu dzakapetwa-zvisina kunaka (hormone receptor-negative uye HER2-isina). Chemotherapy inogona zvakare kushandiswa pamwe chete neHER2-yakanangwa ekurapa kweHER2-positive kenza yemazamu.

Chemotherapy inogona kushandiswa mune zvakakomba zviitiko zvehormone receptor-yakanaka, HER2-negative cancer.

Kana yekutanga chemotherapy mushonga, kana musanganiswa wemishonga, ikamira kushanda uye gomarara richipararira, wechipiri kana wechitatu mushonga unogona kushandiswa.

Kutsvaga kurapwa kwakanaka kunogona kutora imwe kuyedza uye kukanganisa. Chii chakanakira mumwe munhu hazvinganzi chakakodzera iwe. Tevedza chirongwa chako chekurapa uye utaure nachiremba wako. Vaitei vazive kana chimwe chinhu chiri kana kuti chisiri kushanda.

Unogona kunge uine mazuva akaoma kumberi, asi zvinobatsira kuziva nezvese marapirwo aungaitwa.