Calcinosis Cutis

Zvemukati

• Mhando dzecalcinosis cutis
• Zviratidzo zvecalcinosis cutis
• Zvinokonzera calcinosis cutis
• Kuverenga Dystrophic
• Metastatic kuverenga
• Idiopathic kuverenga
• Iatrogenic kuverenga
• Calciphylaxis
• Mukubatana ne scleroderma
• Kuongororwa kwecalcinosis cutis
• Kurapa kwecalcinosis cutis
• Zvinodhaka
• Kuvhiya
• Mamwe marapirwo
• Maonero ecalcinosis cutis

Mhedziso

Calcinosis cutis ndiko kuunganidzwa kwe calcium salt makristasi muganda rako. Iyo macalcium deposits akaomarara mapundu ayo asinganyungudike. Chimiro uye saizi yemaronda anosiyana.

Ichi chiitiko chisingawanzo chine zvikonzero zvakawanda zvakasiyana. Izvi zvinotangira kubva kuhutachiona nekukuvara kuzvirwere zvehurongwa senge itsvo kutadza.

Kazhinji calcinosis cutis haina zviratidzo. Asi pane dzimwe nguva, zvinogona kurwadza kwazvo. Mishonga iripo, kusanganisira kuvhiyiwa, asi macalcium maronda anogona kudzoka.

Mhando dzecalcinosis cutis

Kune mashanu madiki ecalcinosis cutis:

• Kuverenga Dystrophic. Iyi ndiyo yakajairika mhando yecalcinosis. Izvo zvinoitika panogadzirwa ganda kana kupiswa. Izvo hazvirevi zvisina kujairika mazinga e calcium kana phosphorus mumuviri.
• Metastatic kuverenga. Izvi zvinoitika kune vanhu vane calcium uye phosphorus mazinga akaenzana zvakanyanya.
• Idiopathic kuverenga. Iyi mhando yecalcinosis cutis haina chikonzero chiri pachena. Inowanzoitika mune imwe nzvimbo yemuviri chete.
• Iatrogenic kuverenga. Iyi mhando yecalcinosis cutis inoguma kubva kunzira yekurapa kana kurapwa, kazhinji netsaona. Semuenzaniso, vacheche vanogona kuve iatrogenic calcification pachitsitsinho, zvichikonzerwa nezvitsitsinho zvimiti kutora ropa.
• Calciphylaxis. Iyi isingawanzo uye yakakomba mhando yecalcinosis cutis inowanzoitika kune vanhu vane itsvo kutadza, vakagamuchira itsvo kuisirwa, kana vari pane dialysis. Inokanganisa tsinga dzeropa muganda kana mafuta layer.Calcium uye phosphate mazinga mumuviri haana kujairika.

Zviratidzo zvecalcinosis cutis

Kuonekwa uye nzvimbo yecalcinosis cutis zvinoenderana nechinokonzera chikonzero. Iwo maronda anowanzo kuve akaomarara, machena-yero mapundu paganda pamusoro. Dzinotanga zvishoma nezvishoma uye dzinosiyana pakukura.

Iwo maronda anogona kunge asina zviratidzo, kana anogona kunge ari akakomba, anorwadza, kana kuburitsa chinhu chena. Muzviitiko zvisingawanzo, chironda chinogona kutyisidzira hupenyu.

Pano pane nzvimbo apo maronda anowanzoonekwa mune yega yega subtypes yecalcinosis cutis:

• Kuverenga Dystrophic. Iwo mapundu anoitika munzvimbo yekukuvara kwetishu. Chaizvoizvo nzvimbo dziri kumberi, magokora, zvigunwe, uye mabvi. Iine lupus, maronda acho anoitika pamaoko nemakumbo, magaro, uye pasi pemaronda emaronda.
• Metastatic kuverenga. Mapundu ari akaenzana akatenderedza majoini: mabvi, magokora, kana mapendekete. Dzinogona zvakare kuumbika dzakatenderedza nhengo dzemukati, senge mapapu, itsvo, tsinga dzeropa, kana dumbu. Maronda akakomberedza majoini anogona kudzikamisa kufamba apo ganda rinoomarara.
• Idiopathic kuverenga. Izvi zvinowanzo bata nzvimbo imwe chete yemuviri. Izvo zvinogona kuitika kutenderedza makuru majoini, chikosoro, musoro, mazamu, nhengo yemurume, iyo vulva, kana maoko nemakumbo. Muvana zvinogona kunge zviri kumeso. Izvo zvipembenene zvinogona kunge zvichena kubuda.
• Iatrogenic kuverenga. Ronda racho rinowanikwa panzvimbo yekurapa kana yekurapa nzira inobaya ganda.
• Calciphylaxis. Maronda eganda anowanzo kuve pamakumbo kana trunk, kunyanya nzvimbo dzakakora senge mazamu, magaro, uye mudumbu. Izvo zvipembenene zvine mavara anotarisa uye anorwadza. Anogona kuve maronda asingarape, kana anogona kuita maronda. Iwo maronda anogona kuperekedzwa nezvimwe zviratidzo, senge kuneta uye kushaya simba.

Zvinokonzera calcinosis cutis

Calcinosis cutis isingawanzo asi ine dzakasiyana siyana zvikonzero, zvinoenderana ne subtype:

Kuverenga Dystrophic

Muzhinji, kukuvara kwemasuru kunotungamira kune phosphate mapuroteni anoburitswa nemasero anofa ayo anozoverengera, achiumba calcium salts. Iko kukuvara kwetishu kunogona kuuya kubva:

• zvirwere
• mamota
• acne
• zvinobatanidza zvinyama zvirwere zvakadai se lupus, systemic sclerosis, kana dermatomyositis

Metastatic kuverenga

Kana calcium phosphate yemuviri yakakwira zvisina kujairika, inogadzira calcium salts iyo inogadzira maqhubu paganda. Zvinokonzera zviyero zvisina kujairika zvecalcium uye phosphate ndezvi:

• chisingaperi itsvo kutadza (chinonyanya kukonzera)
• yakawandisa vhitamini D
• hyperparathyroidism (yakawedzera parathyroid gland inogadzira thyroid hormone)
• sarcoidosis (mapoka emaseru anogumbura anoumba mumapapu, lymph node, ganda, uye zvimwe zvikamu zvemuviri)
• mukaka-alkali syndrome (yakawandisa calcium kubva kuzvikafu kana maantacids)
• zvirwere zvepfupa, zvakadai sechirwere chePaget

Idiopathic kuverenga

Kusiyana nemhando mbiri dzekutanga dzekalcinosis cutis, idiopathic calcification inoitika isina kukuvara kwemasuru uye isina huwandu hwakawanda hwecalcium kana phosphorus. Idiopathic zvinoreva "hapana chikonzero chinozivikanwa." Kune matatu marudzi:

• nodules yemhuri, ayo anowanzoonekwa mune vechidiki vane hutano kana vana vadiki
• subepidermal nodules, iyo inowoneka pazasi peganda
• nodules pane chikanda

Iatrogenic kuverenga

Icho chinokonzeresa iatrogenic calcification inzira yekurapa iyo netsaona inotungamira kune calcium munyu inoiswa sedivi mhedzisiro. Iyo michina yeiyi haizivikanwe. Mimwe miitiro inobatanidzwa ndeiyi:

• kutungamira kwemhinduro dzine calcium uye phosphate
• kubata kwenguva refu neakaguta calcium chloride electrode paste panguva ye electroencephalograph kana electromyograph
• intravenous calcium gluconate, calcium chloride, uye para-aminosalicylic acid mukurapa tibhii.
• chitsitsinho chinonamira mune vacheche

Calciphylaxis

Icho chinokonzera calciphylaxis chinoramba chisina chokwadi. Izvo zvisingawanzoitika, kunyangwe zvimwe zvezvinhu zvakabatana zvakajairika.

• chisingaperi itsvo kutadza
• kufutisa
• chirwere cheshuga
• hyperparathyroidism

Mukubatana ne scleroderma

Calcinosis cutis inowanzoitika pamwe ne systemic sclerosis (scleroderma). Inowanikwa kunyanya mune mashoma fomu yechirwere ichi, inozivikanwa seyakaganhurwa cutaneous systemic sclerosis (CREST).

Anofungidzirwa yeavo vane CREST syndrome ichavandudza calcinosis cutis mushure.

Maronda acho anowanzoonekwa akatenderedza zvigunwe nemagokora uye anogona kuvhurika obva aburitsa chakachena chena.

Kuongororwa kwecalcinosis cutis

Kusarudza rudzi rwecalcinosis cutis yauinayo kwakakosha mukufunga kurapwa kwakakodzera. Chiremba wako anokuongorora uye otora nhoroondo yako yekurapa uye ndokubvunza mibvunzo nezve zviratidzo zvako.

Chiremba angango kuraira bvunzo dzinoverengeka dzevarabhoritari kuti aone chinokonzera chinokonzera calcinosis cutis yako

• kuongororwa kweropa kuti uone kana calcium yako nephosphate zviyero zvakakwirira zvisina kujairika, kutsvaga mamaki erupus uye anogona kunge mamota, uye kutonga zvisina kujairika parathyroid uye vhitamini D mazinga.
• metabolic bvunzo kutonga kunze itsvo matambudziko
• X-rays, CT scans, kana bone scans (scintigraphy) kutarisa padanho reiyo calcification.
• biopsy yemaronda
• mamwe mabvunzo akasarudzika kutarisa dermatomyositis (chirwere chinoputira) uye mukaka-alkali syndrome

Tekinoroji nyowani iri kuvandudzwa yekubatsira kuongororwa ndeyemberi vibrational spectroscopy. Iyi nzira yekuongorora inoshandisa Fourier shandura infrared (FT-IR) kana kuongorora kweRaman spectroscopic. Iyo inokurumidza kuzivisa makemikari akaumbwa eiyo calcinosis cutis maronda. Inogona zvakare kufanotaura kuwedzera kwechirwere.

Kurapa kwecalcinosis cutis

Kurapa kwecalcinosis cutis kunoenderana nechikonzero chechirwere kana chikonzero.

Zvinodhaka

Mhando dzakasiyana dzemishonga dzinogona kuyedzwa kurapa maronda, asi kubudirira kwavo kwave neronda.

Kune maronda madiki, zvinodhaka zvinosanganisira:

• warfarin
• ceftriaxone
• intravenous immunoglobulin (IVIG)

Kune maronda akakura, zvinodhaka zvinosanganisira:

• diltiazem
• bisphosphonates
• zvimiro
• aruminiyamu hydroxide

Chidzidzo che2003 chakataura kuti yakaderera dosi yemishonga inorwisa mabhakitiriya minocycline yaive inoshanda mukugadzirisa marwadzo uye huwandu hwezvironda muvanhu vane CREST syndrome. Nyaya yepamusoro sodium thiosulfate inogonawo kubatsira.

Kuvhiya

Kana maronda ako achirwadza, utapukirwa kazhinji, kana kukanganisa mashandiro ako, chiremba wako anogona kukurudzira kuvhiyiwa. Asi maronda anogona kudzoka mushure mekuvhiyiwa. Zvinokurudzirwa kuti kuvhiyiwa kutange nechikamu chidiki chechironda.

Mamwe marapirwo

Kurapa kutsva kwakarongwa hematopoietic stem cell kuisirwa (HSCT), iyo inotsiva masero emunhu ekugadzira ropa. Izvi zvave zvichishandiswa kurapa zvimwe autoimmune hosha.

Laser kurapa uye kuvhunduka wave lithotripsy (iyo Ultrasound kurapwa inoshandiswa kuputsa itsvo matombo) ndiwo marapirwo.

Maonero ecalcinosis cutis

Maonero ecalcinosis cutis anoenderana nechikonzero chechirwere kana chikonzero, uye kuomarara kwezvironda zvako. Kurapa kwazvino kunogona kubatsira, uye kurapa kutsva kuri kugadzirwa. Taura nachiremba wako nezve maitiro ekugadzirisa zviratidzo zvako uye nekurapa mudzi wedambudziko.