Chii chinonzi Calcitonin bvunzo uye inoitwa sei

Zvemukati

• Chii ichochi
• Maitirwo ebvunzo
• Maitiro ekuyera bvunzo mhedzisiro

Calcitonin ihormone inogadzirwa muhutachiona, iro basa rayo kudzora huwandu hwecalcium inotenderera muropa, kuburikidza nemhedzisiro sekudzoreredza kubviswa kwecalcium kubva mumapfupa, kudzikisa kunwa kwecalcium nematumbu uye kuwedzera kubuda ne itsvo.

Chiratidzo chikuru cheiyo calcitonin bvunzo kutsvagiswa kwerudzi rwecancer yegonyeti inonzi medullary thyroid carcinoma, ichifungidzirwa sechiremera chechirwere ichi, sezvo ichikonzera kukwidziridzwa kwakakosha kwehomoni iyi. Kuongororwa kwekuvapo kwehutachiona C-cell hyperplasia zvakare chimwe chiratidzo chinowanzoitika, kunyangwe hormone iyi inogona zvakare kukwidziridzwa mune mamwe mamiriro, semapapu kana kenza yemazamu, semuenzaniso.

Semushonga, kushandiswa kwecalcitonin kunogona kuratidzwa pakurapa zvirwere zvakaita se osteoporosis, yakawandisa calcium muropa, chirwere chePaget kana reflex systematic dystrophy. Kana iwe uchida kuziva zvakawanda nezve calcitonin, ona kuti chii calcitonin uye zvazvinoita.

Chii ichochi

Iyo calcitonin bvunzo inogona kurairwa ye:

• Kuongorora kuvapo kwemedullary thyroid carcinoma;
• Kuongororwa kwehyperplasia yeC maseru, ayo ari maseru ehutachiona anogadzira calcitonin;
• Kuongororwa kwehama dzevarwere vane medullary thyroid carcinoma, yekutanga kuona bundu;
• Kucherechedzwa kwemhinduro kune kurapwa kwe medullary thyroid carcinoma;
• Kuteedzerwa kwekenza mushure mekubviswa kwetachiona, sezvazvinotarisirwa kuti hunhu hwakaderera kuitira kurapwa.

Kunyangwe izvi zviri izvo zvinoratidza kukuru, zvinofanirwa kuyeukwa kuti calcitonin inogonawo kuwedzerwa mune mamwe mamiriro, senge mamwe marudzi ekenza, senge leukemia, mapapu, pancreatic, kenza yemazamu kana yeprostate, pamberi pechirwere chetsvo chisingaperi, panguva hutachiona hutachiona, hypergastrinemia, kana semhedzisiro yehyperparathyroidism hypercalcemia kana mamwe mamiriro.

Maitirwo ebvunzo

Calcitonin dosage inoitwa murabhoritari, pakukumbira kwachiremba, uko kunoitwa muyero weropa kuti uwane masosi ekutanga.

MaCalcitonin tsika anokanganiswa nemamiriro akati wandei, anosanganisira kushandiswa kwemimwe mishonga, yakadai seOmeprazole kana corticosteroids, zera, nhumbu, kuputa uye kunwa doro, saka nzira yekuita kuti bvunzo iwedzere kuvimbika ndeyekuzviita pamwe chete nachiremba calcium kana pentagastrin infusion bvunzo, zvimwe kunze kwesimba rinosimudzira recalcitonin secretion.

Iyo calcitonin inosimudzira bvunzo ine calcium infusion ndiyo inonyanya kuwanikwa, uye inoitwa mangwanani, padumbu risina chinhu. Calcium yakajowa kuburikidza neiyo tsinga, pa0, 2, 5 uye 10 maminetsi mushure mekunyorwa, kuongorora kana iyo yekuwedzera maitiro inoonekwa seyakajairika kana kwete.

Maitiro ekuyera bvunzo mhedzisiro

Zvakajairwa calcitonin mareferensi maitiro anogona kusiyana zvichienderana neirabhoritari inoita bvunzo. Maitiro akajairwa ndeaya ari pazasi pe8.4 pg / ml mune varume uye 5 pg / ml mune vakadzi. Mushure mekukurudzirwa kwecalcium, iwo ari pazasi pe30 pg / ml uye akanaka kana ari pamusoro pe100 pg / ml anogona kutorwa seakajairwa. Pakati pe30 uye 99 pg / dl, iyo bvunzo inoonekwa seinogadzikana, uye kumwezve bvunzo dzinofanirwa kuitwa kuratidza chirwere.