CBD yeFibromyalgia

Zvemukati

• Tsvagiridzo yeCDD ye fibromyalgia
• Pakutanga zvidzidzo
• 2019 chiDutch kudzidza
• 2019 Israeli kudzidza
• CBD mabatiro ekurapa
• CBD mhedzisiro
• Outlook

Kunzwisisa cannabidiol (CBD)

Cannabidiol (CBD) chinhu chemakemikari chakagadzirwa kubva ku cannabis. CBD haisi psychoactive, kusiyana ne tetrahydrocannabinol (THC), imwe chibereko checannabis.

CBD inofungidzirwa kumutsa serotonin receptors. Inoita basa mu:

• kurwadziwa kunzwisisika
• kuchengetedza tembiricha yemuviri
• kuderedza kuzvimba

Zvinoenderana nezvazvino zvidzidzo, CBD zvakare:

• inobatsira kudzikisira zviratidzo zvekuora mwoyo
• inogona kudzivirira zviratidzo zvepfungwa

Aya mabhenefiti ndiwo anoita kuti CBD ive inonakidza imwe nzira yekurapa kwekutambudzika kwekurwadziwa senge fibromyalgia.

Tsvagiridzo yeCDD ye fibromyalgia

Fibromyalgia chirwere chisingaperi chinorwadza chinokonzera kurwadziwa kwemhasuru pamwe nekuwedzera ku:

• kuneta
• kushaya hope
• nyaya dzekuziva

Inonyanya kubata vakadzi, uye pari zvino hapana mushonga unozivikanwa wemamiriro acho. Nekudaro, sarudzo dzekurapa dziripo dzino tarisa pakurapa kwekutambudzika.

CBD yakashandiswa kudzikamisa marwadzo ekurwara nekusingaperi. Inotaridzwa seimwe nzira yekutora mishonga yeopioid iyo inogona kupindwa muropa.

Nekudaro, iyo Kudya neDrug Administration (FDA) haina kubvumidza CBD senzira yekurapa ye fibromyalgia kana zvimwe zvakawanda mamiriro. Iyo CBD-yakavakirwa mushonga mushonga Epidiolex, kurapa kwepfari, ndiyo chete chigadzirwa cheCDD icho FDA-inogamuchirwa uye inodzorwa.

Parizvino hapana zvidzidzo zvakatsikiswa pane fibromyalgia zvinotarisa mhedzisiro yeCBD pachayo. Zvisinei, kumwe kutsvagurudza kunotarisa mhedzisiro ye cannabis, iyo inogona kunge iine akawanda cannabinoids, pane fibromyalgia.

Mhedzisiro yacho yakasanganiswa. Zvimwe zvidzidzo zvevanhu zvinodiwa.

Pakutanga zvidzidzo

Yakawanikwa kuti CBD inogona kushandiswa kubvisa marwadzo europathic. Vatsvakurudzi vakagumisa kuti cannabinoids senge CBD inogona kunge iri chinhu chinobatsira kune mimwe mishonga yekurwadziwa.

Chidzidzo che2011 chakatarisa vanhu makumi mashanu nevatanhatu vane fibromyalgia. Vazhinji vevatori vechikamu vaive vakadzi.

Nhengo dzekudzidza dzaive nemapoka maviri:

• Rimwe boka raive nevane makumi maviri neshanu vatori vechikamu vange vasiri vashandisi vecannabis.
• Boka rechipiri raive nevane makumi maviri neshanu vatori vechikamu vaive vashandisi ve cannabis Kuwanda kwekushandisa kwavo kwecannabis, kana huwandu hwecannabis yavakashandisa, zvakasiyana.

Maawa maviri mushure mekushandisa cannabis, vashandisi vecannabis vakawana mabhenefiti akadai se:

• kurwadziwa kwakaderera uye kuomarara
• kuwedzera kwekurara

Ivo zvakare vaive nezvakakwirira zvishoma zvehutano hwepfungwa zviyero kupfuura ivo vasiri-vashandisi.

2019 chiDutch kudzidza

Chidzidzo cheDutch che2019 chakatarisa zvinoitika zvecannabis pavakadzi makumi maviri vane fibromyalgia. Mukufamba kwese kwekudzidza, mumwe nemumwe anotora chikamu akagashira marudzi mana e cannabis:

• huwandu husinga tsanangurike hwenzvimbo dzakasiyana-siyana, iyo yaive isina CBD kana THC
• 200 mamirigiramu (mg) emhando dzakasiyana ane huwandu hwakakura hwese ari maviri CBD uye THC (Bediol)
• 200 mg yezvakasiyana-siyana zvine huwandu hwakakura hweCBD uye huwandu hwakaderera hweTC (Bedrolite)
• 100 mg yezvakasiyana ine yakaderera huwandu hweCBD uye huwandu hwakawanda hweTC (Bedrocan)

Vatsvaguriri vakaona kuti marwadzo ekuzvarwa anongoitika evanhu vanoshandisa dzakasiyana-siyana dzeplacebo akafanana nemarwadzo ekuzvarwa nawo evanhu vanoshandisa mamwe emhando dzisiri dze placebo

Nekudaro, Bediol, iyo yakakwira muCDD uye THC, yakaunza zororo kune hombe nhamba yevanhu kupfuura iyo placebo yakaita. Yakakonzera kudzikiswa makumi matatu muzana ekurwadziwa kwepakarepo mu18 pavatori vechikamu makumi maviri. Iyo placebo yakakonzeresa makumi matatu muzana kudzikira kwekurwadziwa kwepakarepo muvatori vechikamu gumi nerimwe.

Kushandiswa kweBediol kana Bedrocan, ese ari maviri akakwira-THC mhando, zvakanyanya kuvandudzwa kwekumanikidzwa kwekutambudzika kana uchienzaniswa neiyo placebo.

Bedrolite, iyo yakakwira muCBD uye yakaderera muTHC, haina kuratidza chero humbowo hwekukwanisa kudzikamisa marwadzo eakaerekana kana anomutsa.

2019 Israeli kudzidza

Muchidzidzo che2019 cheIsrael, mazana evanhu vane fibromyalgia akaonekwa mukati memwedzi inosvika mitanhatu. Pakati pevatori vechikamu, 82 muzana vaive vakadzi.

Vadzidzi vakapinda muchidzidzo vakagamuchira nhungamiro kubva kuna vanamukoti vasati vatora cannabis yekurapa. Vanamukoti vakapa mazano pane:

• iwo gumi nematanhatu emhando dzecannabis dzaivapo
• nzira dzekuendesa
• dosages

Vese vatori vechikamu vakatanga nemutero wakaderera wecannabis, uye madheji akawedzerwa zvishoma nezvishoma pamusoro pechidzidzo. Iyo yepakati yakatenderwa muyero wecannabis yakatanga pa670 mg pazuva.

Pamwedzi mitanhatu, muyero wepakati wakagamuchirwa wecannabis waive 1,000 mg pazuva. Iyo yepakati yakatenderwa muyero weTHC yaive 140 mg, uye wepakati anotenderwa muyero weCDD waive 39 mg pazuva.

Vatsvaguri vakabvuma kuti kudzidza kwaive nemipimo. Semuenzaniso, ivo vaingokwanisa chete kutevera pamwe neanosvika makumi manomwe muzana yevatori vechikamu. Iko kushandiswa kweakawanda akasiyana masisitimu zvakare kwakaita kuti zvive zvakaoma kuenzanisa zvinokonzeresa zveCBD-zvakapfuma uye THC-zvakapfuma maronda.

Nekudaro, ivo vachiri vakapedzisa kuti kurapa cannabis yaive yakachengeteka uye inoshanda kurapwa kwefibromyalgia.

Pakutanga kwekudzidza, 52.5 muzana yevatori vechikamu, kana vanhu 193, vakatsanangura marwadzo avo seakakwirira. Pakutevera kwemwedzi mitanhatu, chete 7.9 muzana yeavo vakapindura, kana vanhu gumi nevapfumbamwe, vakataura marwadzo akakwirira.

CBD mabatiro ekurapa

Kana iwe uchida kudzivisa iyo psychoactive mhedzisiro yembanje, unogona kuwana zvigadzirwa zveCBDD izvo zvinongova nematanho chete ezviuru zve THC. Kana iwe uchigara munzvimbo ine varaidzo yekuvaraidza kana yekurapa iri pamutemo, unogona kuwana zvigadzirwa zveCBD zvine huwandu hwakanyanya hweTC.

Kunyangwe ivo vese vaine mabhenefiti zvakasiyana, CBD uye TCH zvinogona kushanda zvakanyanya kana zvabatanidzwa. Nyanzvi dzinotaura nezvekudyidzana uku, kana kubatana, se "chiitiko chevapambi."

CBD inoshandawo inopesana neTC-yakanangwa zvinogamuchirwa kudzora zvakashata mbanje, senge paranoia uye kusagadzikana.

Unogona kushandisa CBD munzira dzinoverengeka, kusanganisira:

• Kuputa kana kuputa. Kana iwe uchida kudzikamisa marwadzo epakarepo, kusvuta CBD-yakapfuma cannabis ndiyo inokurumidza nzira yekudzora zviratidzo. Mhedzisiro inogona kugara kusvika maawa matatu. Kuputa kana kufema kunokutendera kuti unyore mukati CBD chaiko kubva kumuti wecannabis, uchipinza makemikari muropa rako nemapapu.
• Zvipenga. Edibles chikafu chakabikwa nemuti wecannabis, kana oiri-inisidzirwa mafuta kana bota. Zvinotora nguva yakareba kuti uwane kusununguka kwezviratidzo, asi mhedzisiro yezvinodyiwa inogona kutora kusvika maawa matanhatu.
• Mafuta anotora. Oiri inogona kuiswa pamusoro, kutorwa nemuromo, kana kunyungudika pasi perurimi uye kupinza mumuromo matukisi.
• Misoro. CBD maoiri anokwanisa kuiswa mumusoro wemafuta kana mabharisamu uye oiswa wakanangana neganda. Izvi zvigadzirwa zveCDD zvinogona kuve sarudzo inoshanda yekudzora kuzvimba uye kubatsira nekurwadziwa kwekunze.

Panogona kuve nenjodzi dzekufema pakusvuta kana kuputa mbanje. Vanhu vane asthma kana mapapu mamiriro havafanirwe kushandisa nzira iyi.

Iwe unofanirwa zvakare kuteedzera kuraira kwedosi zvakanyatsonaka, kunyanya nezvinodyiwa, kudzivirira zvakashata mhedzisiro yekutora yakawandisa.

CBD mhedzisiro

Cannabidiol inofungidzirwa kuva yakachengeteka uye ine mashoma mhedzisiro. Nekudaro, vamwe vanhu vakasangana nemhedzisiro inotevera mushure mekushandisa CBD:

• kuneta
• manyoka
• nzara inoshanduka
• uremu hunochinja

Chidzidzo pamakonzo akabatanidza CBD kudya kune chiropa chepfu. Nekudaro, mimwe mbeva dziri muchidzidzo ichocho dzaive dzakamanikidzwa-kudyiwa huwandu hwakawanda hweCBD muchimiro cheCBD-yakafuma cannabis yakatorwa.

Kubatana kwezvinodhaka kunogoneka neBDD. Ziva nezvazvo kana urikutora zvimwe zvinowedzera kana mishonga.

CBD, kunge grapefruit, zvakare inokanganisa ma cytochromes P450 (CYPs). Iri boka re enzyme rakakosha kune metabolism metabolism.

Outlook

Vatsvagiri vachiri kuongorora kuti CBD inogona kunyatso kurapa kusagadzikana kurwadziwa marwadzo. Zvimwe zvidzidzo zvinodiwa. Kune dzimwe nyaya dzekubudirira, asi CBD haina FDA-inogamuchirwa ye fibromyalgia. Zvakare, kutsvagisa kuchiri kuzotiratidza iwo marefu-kwenguva mhedzisiro yeCDD panyama.

Kusvikira zvimwe zvazivikanwa, echinyakare fibromyalgia kurapwa kunokurudzirwa.

Kana iwe ukafunga kushandisa zvigadzirwa zveCBD kurapa kurwadziwa, ita chokwadi chekutanga kubvunza nachiremba. Vanogona kukubatsira kuti udzivise zvakashata mhedzisiro kana kusangana kunokuvadza nemishonga yako yazvino nemishonga.