Munyori: Peter Berry
Zuva Rekusika: 18 Chikunguru 2021
Gadziridza Zuva: 14 Mbudzi 2024
Anonim
Cirrhosis - causes, symptoms, diagnosis, treatment, pathology
Vhidhiyo: Cirrhosis - causes, symptoms, diagnosis, treatment, pathology

Zvemukati

Mhedziso

Cirrhosis ndiko kuora kwakakomba kwechiropa uye kushomeka kwechiropa basa kunoonekwa pamatanho ekupedzisira echirwere chechiropa chisingaperi. Iyo vanga inowanzo kuve inokonzerwa nekuratidzwa kwenguva refu kune chepfu senge doro kana hutachiona hutachiona. Chiropa chiri kumusoro kwekurudyi kwedumbu pazasi pembabvu. Iyo ine akawanda akakosha mashandiro emuviri. Izvi zvinosanganisira:

  • kuburitsa bile, iyo inobatsira muviri wako kutora mafuta ezvekudya, cholesterol, uye mavitamini A, D, E, uye K
  • kuchengetedza shuga nemavhitamini zvekuzoshandiswa nemuviri
  • kuchenesa ropa nekubvisa chepfu senge doro nemabhakitiriya kubva muchirongwa chako
  • kugadzira ropa rinovhara mapuroteni

Sekureva kweNational Institutes of Health (NIH), cirrhosis ndiyo yegumi nembiri inokonzera kufa nekuda kwechirwere muUnited States. Izvo zvinowanzo bata varume kupfuura vakadzi.

Iyo cirrhosis inokura sei

Chiropa inhengo yakasimba uye inowanzo gonesa maseru akakuvara. Cirrhosis inokura kana zvinhu zvinokanganisa chiropa (senge doro uye chirwere chisingaperi chehutachiona) chiripo kwenguva yakareba. Kana izvi zvikaitika, chiropa chinokuvadzwa uye kupiswa. Chiropa chine mavanga hachigone kushanda nemazvo, uye pakupedzisira izvi zvinogona kukonzera cirrhosis.


Cirrhosis inokonzera chiropa kudzikira uye kuomarara. Izvi zvinoita kuti zvive zvakaoma kuti ropa rine hupfumi riwedzere kuyerera muchiropa kubva muvharo remusuwo. Iyo portal vein inotakura ropa kubva kunhengo dzekugaya kuenda kuchiropa. Iko kumanikidza kuri mukati mechipenga tsinga kunokwira apo ropa risingakwanise kupfuura muchiropa. Mhedzisiro mhedzisiro chiitiko chakakomba chinonzi portal hypertension, mune iyo tsinga inokura yakakwira BP. Iyo inosuruvarisa mhedzisiro yeiyo portal hypertension ndeyekuti iyi yakanyanya-kumanikidza sisitimu inokonzera backup, iyo inotungamira kune esophageal varices (kunge varicose veins), iyo inogona kuzoputika uye kubuda ropa.

Zvinowanzoitika zvikonzero zvecirrhosis

Zvinonyanya kukonzera cirrhosis muUnited States inguva refu yehutachiona hepatitis C hutachiona uye kusingaperi kunwa doro zvisina kufanira. Kufutisa zvakare chikonzero checirrhosis, kunyangwe hachisi chakakurumbira sekudhakwa kana hepatitis C. Kufutisa kunogona kuita njodzi pachayo, kana mukubatana nekudhakwa uye hepatitis C.

Sekureva kweNIH, cirrhosis inogona kukura mukati mevakadzi vanonwa zvinopfuura zviviri zvinwiwa zvinodhaka pazuva (kusanganisira doro newaini) kwemakore mazhinji. Kune varume, kunwa zvinopfuura zvitatu zvinwiwa pazuva kwemakore zvinogona kuvaisa panjodzi yechirrhosis. Zvisinei, huwandu hwacho hwakasiyana kumunhu wese, uye izvi hazvireve kuti munhu wese akambonwa zvinwiwa zvinwiwa anozoita chirwere checirrhosis. Cirrhosis inokonzerwa nedoro inowanzo kuve mhedzisiro yekugara uchinwa zvinopfuura izvi zviyero mukati memakore gumi kana gumi nemaviri.


Hepatitis C inogona kubatwa kuburikidza nekuita zvepabonde kana kuratidzwa kune hutachiona hweropa kana zvigadzirwa zveropa. Zvinokwanisika kuburitswa neropa rine hutachiona kuburikidza nesingano dzakashatiswa dzechero ipi sosi, kusanganisira nyora, kuboora, kushandisa zvinodhaka zvisina kufanira, uye kugovana tsono. Hepatitis C haigone kutapuriranwa neropa muUnited States nekuda kweyakaomarara mwero wekuongororwa kubhengi reropa.

Zvimwe zvikonzero zvechirrhosis zvinosanganisira:

  • Hepatitis B: Hepatitis B inogona kukonzera kuzvimba kwechiropa uye kukuvara uko kunogona kukonzera cirrhosis.
  • Hepatitis D: Iyi mhando yehepatitis inogona zvakare kukonzera cirrhosis. Inowanzoonekwa kune vanhu vanotova nehutachiona B.
  • Kuzvimba kunokonzerwa ne autoimmune chirwere: Autoimmune hepatitis inogona kuve nemajini chinokonzera. Sekureva kweAmerican Liver Foundation, inenge makumi manomwe muzana yevanhu vane autoimmune hepatitis vakadzi.
  • Kukuvadza kune iyo ducts, iyo inoshanda kukweva bile: Mumwe muenzaniso wemamiriro akadaro ndiwo ekutanga biliary cirrhosis.
  • Kukanganiswa kunokanganisa kugona kwemuviri kubata simbi nemhangura: Mienzaniso miviri hemochromatosis uye chirwere cheWilson.
  • Mishonga: Mishonga inosanganisira kunyora uye kupfuura-the-counter zvinodhaka senge acetaminophen, mamwe maantibhakitiriya, uye mamwe emishonga yekudzvinyirira, anogona kutungamira kuchirapa.

Zviratidzo zvecirrhosis

Zviratidzo zvechirrhosis zvinoitika nekuti chiropa hachikwanisi kuchenesa ropa, kuputsa muchetura, kugadzira mapuroteni anovharisa, uye kubatsira nekutora kwemafuta uye mavhitaminzi ane mafuta. Kazhinji hapana zviratidzo kusvikira hosha yawedzera. Zvimwe zvezviratidzo zvinosanganisira:


  • kuderera kwechido
  • mhino inobuda ropa
  • jaundice (yero discoloration)
  • tsinga dzakaita dandemutande dziri pasi peganda
  • kuonda
  • anorexia
  • ganda rinonhuwa
  • kushaya simba

Zvimwe zviratidzo zvakakomba zvinosanganisira:

  • kuvhiringidzika uye kunetseka kufunga zvakajeka
  • kuzvimba mudumbu (ascites)
  • kuzvimba kwemakumbo (edema)
  • kushaya simba
  • gynecomastia (apo vanhurume vanotanga kukura matumbu emvere)

Iyo cirrhosis inoonekwa sei

Kuongororwa kwechirrhosis kunotanga nenhoroondo yakadzama uye bvunzo dzepanyama. Chiremba wako achatora yakazara nhoroondo yezvokurapa. Iyo nhoroondo inogona kuburitsa kwenguva refu kunwa doro zvisina mwero, kuratidzwa kune hepatitis C, nhoroondo yemhuri yezvirwere zvemuviri, kana zvimwe zvinenjodzi. Iko kuongorora kwepanyama kunogona kuratidza zviratidzo senge:

  • ganda rakachenuruka
  • yero maziso (jaundice)
  • matsvuku akatsvuka
  • kudedera kwemaoko
  • chiropa chakakura kana chirwatata
  • machende madiki
  • zvakawandisa zvemazamu tishu (mune varume)
  • kuderera kusvinura

Bvunzo dzinogona kuratidza kuti chiropa chave kukuvara zvakadii. Mimwe bvunzo inoshandiswa pakuongorora cirrhosis ndeiyi:

  • kuzadza huwandu hweropa (kuratidza anemia)
  • coagulation ropa bvunzo (kuti uone kukurumidza kuvhara ropa)
  • albumin (kuyedza puroteni inogadzirwa muchiropa)
  • chiropa chinoshanda bvunzo
  • alpha fetoprotein (kuongororwa kenza yechiropa)

Kuwedzera bvunzo dzinogona kuongorora chiropa dzinosanganisira:

  • yepamusoro endoscopy (kuona kana esophageal varices aripo)
  • Ultrasound scan yechiropa
  • MRI yemudumbu
  • CT scan yemudumbu
  • chiropa biopsy (iyo chaiyo bvunzo yecirrhosis)

Matambudziko kubva ku cirrhosis

Kana ropa rako risingakwanise kupfuura nepachiropa, rinogadzira backup kuburikidza nedzimwe tsinga senge idzo dziri mudumbu. Iyi backup inonzi esophageal varices. Tsinga idzi hadzina kuvakwa kuti dzibate kumanikidza kwakanyanya, uye dzinotanga kubuda kubva mukuwedzera kuyerera kweropa.

Mamwe matambudziko kubva ku cirrhosis anosanganisira:

  • kupwanya (nekuda kwekudzikira kweplatelet kuverenga uye / kana kusagadzikana kwekugwamba)
  • kubuda ropa (nekuda kwekudzikira kwekuvhara mapuroteni)
  • kunzwisiswa kwemishonga (iyo chiropa inogadzira mishonga mumuviri)
  • itsvo kutadza
  • gomarara rechiropa
  • insulin kudzvinyirira uye mhando 2 chirwere cheshuga
  • hepatic encephalopathy (kuvhiringidzika nekuda kwemhedzisiro yeropa chepfu pauropi)
  • nduru (kupindirana nenyuchi kuyerera kunogona kukonzera kuti bile riome uye kuumba matombo)
  • esophageal varices
  • akawedzera spleen (splenomegaly)
  • edema uye ascites

Kurapa kwecirrhosis

Kurapa kwecirrhosis kunosiyana zvichienderana nezvakakonzera uye kuti chirwere ichi chaenderera mberi zvakadii. Mimwe mishonga ingarayirwa nachiremba wako inosanganisira:

  • beta blockers kana nitrate (yeiyo portal hypertension)
  • kurega kunwa (kana cirrhosis ichikonzerwa nedoro)
  • mabhanji maitiro (anoshandiswa kudzora kubuda ropa kubva esophageal varices)
  • intravenous antibiotics (kurapa peritonitis inogona kuitika ne ascites)
  • hemodialysis (kuchenesa ropa revaya vari mukutadza kwetsvo)
  • lactulose uye yakaderera mapuroteni chikafu (kurapa encephalopathy)

Chiropa kuisirwa inzira yesarudzo yekupedzisira, kana kumwe kurapwa kuchikundikana

Vese varwere vanofanira kurega kunwa doro. Mishonga, kunyangwe pamusoro-pe-pekutengesa, haifanire kutorwa usina kubvunza chiremba wako.

Kudzivirira cirrhosis

Kudzidzira bonde rakachengeteka nemakondomu kunogona kudzikisa njodzi yekuwana hepatitis B kana C. MaU anokurudzira kuti vacheche vese uye vanhu vakuru vari panjodzi (sevapi vezvehutano nevashandi vekununura) vabaiwe jekiseni rekurwisa hepatitis B.

Kuva asinganwi, kunwa kudya kwakaringana, uye kuwana kurovedza muviri kwakaringana kunogona kudzivirira kana kunonoka cirrhosis. World Health Organisation inoshuma kuti chete makumi maviri kusvika makumi matatu muzana yevanhu vane hutachiona hwehepatitis B vanozoita cirrhosis kana gomarara rechiropa. Sangano reNational Institute of Health rinoti vanhu vashanu kusvika makumi maviri muzana vane hutachiona hwehepatitis C vanozoita cirrhosis mukati memakore makumi maviri kusvika makumi matatu.

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