Colchicine (Colchis): chii icho, chii chiri uye mashandisiro

Zvemukati

• Chii ichochi
• Kushandisa sei
• 1. Unzenza
• 2. Peyronie chirwere
• Colchicine yekurapa kwe COVID-19
• Ndiani asingafanire kushandisa
• Zvinogona kuitika mhedzisiro

Colchicine mushonga unorwisa-kupisa unoshandiswa zvakanyanya kurapa uye kudzivirira kurwisa kwakanyanya kwe gout. Uye zvakare, inogona zvakare kushandiswa kurapa makesi echirwere chisingaperi, yemhuri fever kana kana uchishandisa madhiragi anoderedza uric acid.

Mushonga uyu unogona kutengwa mumafamasi, mune akajairwa kana ane zita rekutengesa Colchis, mumapaketi ematafura makumi maviri kana makumi matatu, panoratidzwa mushonga.

Chii ichochi

Colchicine mushonga unoshandiswa kurapa zvakanyanya gout kurwisa uye kudzivirira kurwisa kwakanyanya kune vanhu vane chisingaperi gouty arthritis.

Tsvaga kuti chii chinonzi gout, chii chinokonzeresa uye zviratidzo zvinogona kubuda.

Uye zvakare, kurapa nemushonga uyu kunogona kuratidzwa muchirwere chaPeyronie, Mediterranean Family Fever uye mune scleroderma, polyarthritis inosangana nesarcoidosis uye psoriasis.

Kushandisa sei

Maitiro ekushandisa colchicine anosiyana zvichienderana nechiratidzo chayo, zvisinei, mune chero mamiriro ezvinhu zvakakosha kudzivirira kunwisa colchicine pamwe nejusi remuzambiringa, sezvo muchero uyu unogona kudzivirira kupedzwa kwemushonga, kuwedzera njodzi yezvinetso uye mhedzisiro yechibatiso.

1. Unzenza

Nekudzivirira kwekurwiswa kwegout, iyo inokurudzirwa dhizeti iri 1 piritsi re 0.5 mg, imwe kana katatu pazuva, nemuromo. Gout varwere vari kuvhiyiwa vanofanira kutora piritsi rimwe katatu pazuva, maawa masere ese, nemuromo, mazuva matatu zvisati zvaitika uye mazuva matatu mushure mekuvhiya.

Zororo rekurwiswa kwakanyanya kwe gout, muyero wekutanga unofanirwa kunge uri 0.5 mg kusvika 1.5 mg uchiteverwa netabhenakeri 1 paawa imwe chete, kana maawa maviri, kudzamara kurwadziwa kana kusvotwa kuoneka, kurutsa kana manyoka. Muyero haufanire kuwedzerwa pasina kutungamirwa nachiremba, kunyangwe zviratidzo zvikasavandudzika.

Varwere vasingaperi vanogona kuenderera mberi nekurapwa nedhivhosi yekuchengetedza yemapiritsi maviri pazuva, maawa gumi nemaviri, kusvika pamwedzi mitatu, sekuziva kwachiremba.

Muyero wepamusoro wakasvika haufanire kupfuudza 7 mg zuva nezuva.

2. Peyronie chirwere

Kurapa kunofanirwa kutanga ne0.5 mg kusvika ku1.0 mg zuva rega rega, inotungamirwa mune imwe kusvika kune miviri doses, iyo inogona kuwedzerwa kusvika pa2 mg pazuva, inotarisirwa muzvikamu zviviri kusvika zvitatu.

Colchicine yekurapa kwe COVID-19

Zvinoenderana neshumo rekutanga rakaburitswa neMontreal Heart Institute ^[1], colchicine yakaratidza mhedzisiro inofadza pakurapa kwevarwere vane COVID-19. Sekureva kwevaongorori, uyu mushonga unoratidzika kunge unoderedza mwero wekuradzikwa muchipatara nekufa, apo kurapwa kunotanga munguva pfupi mushure mekuongororwa.

Zvisinei, zvichiri kudikanwa kuti mhedzisiro yese yechidzidzo ichi izivikanwe uye kuongororwa nenzvimbo yesainzi, pamwe nekukurudzira kuti uenderere mberi nekuferefeta nemushonga, kunyanya sezvo uri mushonga unogona kukonzeresa mhedzisiro kwete kushandiswa muyero.yakarurama uye pasi pekutarisirwa nachiremba.

Ndiani asingafanire kushandisa

Mushonga uyu haufanire kushandiswa kune vanhu vane allergies kune chero chinhu chiripo mufomula, vanhu vari kurapwa dialysis kana vanhu vane zvakanyanya gastrointestinal, hematological, chiropa, itsvo kana chirwere chemwoyo.

Uye zvakare, haifanire kushandiswa kune vana, vakadzi vane nhumbu kana vakadzi vari kuyamwa.

Zvinogona kuitika mhedzisiro

Mhedzisiro inowanzoitika inogona kuitika nekushandiswa kwemushonga uyu kurutsa, kusvotwa, kurukutika, kutemwa nemusoro, gout, cramp, kurwadziwa mudumbu uye kurwadziwa muhuro uye pharynx. Imwe yakakosha mhedzisiro mhedzisiro, iyo, kana ikasimuka, inofanira kuziviswa nekukurumidza kuna chiremba, sezvo zvichiratidza kuti kurapwa kunofanira kumiswa.

Uye zvakare, kunyangwe iri isingawanzoitika, kurasikirwa nevhudzi, kushushikana kwepelinha, dermatitis, shanduko mukugwamba uye chiropa, allergic reaction, yakawedzera creatine phosphokinase, lactose kusagadzikana, kurwadziwa kwemhasuru, yakaderedzwa nhamba yembeu, yepepuru, kuparadzwa kwemaseru maseru uye chepfu neuromuscular chirwere.