Cerebral Spinal Fluid (CSF) Kuongorora

Zvemukati

• Maitiro eCSF anotorwa sei
• Maitiro akafanana
• Ngozi dzekuputika kwechiuno
• Nei muyedzo wakarairwa
• Zvirwere zvakaonekwa neCSF ongororo
• Zvirwere zvinotapukira
• Hemorrhaging
• Matambudziko ekudzivirira immune
• Mamota
• CSF kuongorora uye multiple sclerosis
• Lab kuyedza uye kuongorora kweCSF
• Kududzira bvunzo dzako
• Kutevera mushure mekuongorora kweCSF

Chii chinonzi kuongorora kweCSF?

Cerebrospinal fluid (CSF) ongororo inzira yekutarisa mamiriro anokanganisa uropi hwako uye musana. Iwo akateedzana eongororo yemarabhoritari yakaitwa pane sampuro yeCSF. CSF ndiyo yakajeka mvura inokwana uye kuendesa zvinovaka muviri kune yako yepakati tsinga system (CNS). Iyo CNS ine huropi uye musana musana.

CSF inogadzirwa neiyo choroid plexus muuropi uye ndokudzorerazve muropa rako. Mvura yacho inotsiviwa zvachose maawa mashoma. Pamusoro pekuendesa zvinovaka muviri, CSF inoyerera yakatenderedza uropi hwako uye musana wechipenga, ichipa dziviriro uye nekutakura marara.

Muenzaniso weCSF unowanzo unganidzwa nekuita lumbar puncture, inozivikanwawo sepombi yemuzongoza. Kuongororwa kwesampuro kunosanganisira kuyerwa uye kuongororwa kwe:

• kumanikidza kwemvura
• mapuroteni
• shuga
• masero matsvuku eropa
• masero machena eropa
• makemikari
• mabhakitiriya
• utachiona
• zvimwe zvinokanganisa zvinhu kana zvekunze zvinhu

Kuongorora kunogona kusanganisira:

• kuyerwa kwehunhu hwepanyama uye kutaridzika kweCSF
• makemikari bvunzo pazvinhu zvinowanikwa musipinha mvura yako kana kuenzanisa nenhanho dzezvinhu zvakafanana zvinowanikwa muropa rako
• sero kuverenga uye kutaipa kwemamwe masero anowanikwa muCSF yako
• kuzivikanwa kwechero hutachiona hunogona kukonzera chirwere chinotapukira

CSF iri kusangana chaiko nehuropi hwako uye musana. Saka kuongorora kweCSF kunoshanda kupfuura kuyerwa kweropa kuti unzwisise zviratidzo zveCNS.Zvisinei, zvinonyanya kuomarara kuwana musana wemvura yepelinha pane muyero weropa. Kupinda mugero wepasipinha netsono kunoda ruzivo rwehunyanzvi nezveatomu yemuzongoza uye nzwisiso yakajeka yechero huropi hwepasi kana mamiriro emuzongoza anogona kuwedzera njodzi yezvinetso kubva munzira.

Maitiro eCSF anotorwa sei

Lumbar puncture kazhinji inotora isingasviki maminetsi makumi matatu. Inoitwa nachiremba anonyanya kudzidziswa kutora CSF.

CSF inowanzo kutorwa kubva kune yako yepazasi kumashure nzvimbo, kana iyo lumbar musana. Zvakakosha kwazvo kuramba wakanyarara panguva yekuita. Nenzira iyi unodzivirira isiriyo yekuisa tsono kuiswa kana kushungurudzika kumusana wako.

Iwe unogona kunge wakagara pasi uye ndokumbirwa kuzendamira pamusoro kuitira kuti musana wako utendeke kumberi. Kana chiremba wako anogona kunge iwe unogona kurara parutivi rwako nemusana wako wakakombama uye mabvi ako akaswededzwa kuchipfuva. Kupeta musana wako kunoita nzvimbo pakati pemapfupa ako muzasi kwezasi.

Paunenge uchinge uri pachinzvimbo, musana wako unoshambidzwa nemhinduro isina mbereko. Iodini inowanzoshandiswa pakutsvaira. Nzvimbo isina chena inochengetedzwa mukati mekuita kwese. Izvi zvinoderedza njodzi yehutachiona.

Kirimu inodzikatidza kana pfapfaidzo inoiswa paganda rako. Chiremba wako anobva abaya jekiseni. Kamwe kana saiti yazara zvinyoronyoro, chiremba wako anoisa yakatetepa yemusana musana pakati pemaviri vertebrae. Rudzi rwakakosha rweX-ray inonzi fluoroscopy dzimwe nguva inoshandiswa kutungamira tsono.

Kutanga, kumanikidza mukati mehenya kunoyerwa uchishandisa manometer. Dzese dzakakwira uye dzakadzika CSF kumanikidza kunogona kuve zviratidzo zvemamwe mamiriro.

Zviratidzo zvemvura zvinotorwa kuburikidza netsono. Kana kuunganidzwa kwemvura kwapera, tsono inobviswa. Nzvimbo yekubaya inogezwa zvakare. Bhandeji rinoiswa.

Iwe uchakumbirwa kuti ugare wakarara pasi kweinenge awa imwe. Izvi zvinoderedza njodzi yemusoro, inova yakajairika mhedzisiro mhedzisiro.

Maitiro akafanana

Dzimwe nguva munhu haakwanise kuve nehuswa hwakakomberedzwa nekuda kwekuremara kumashure, hutachiona, kana kugona kwehuropi. Muzviitiko izvi, imwe inopinda nzira yekuunganidza yeCSF inoda kuiswa muchipatara inogona kushandiswa, senge chimwe cheanotevera:

• Munguva yekubaya kwe ventricular, chiremba wako anochera gomba mudehenya rako uye anoisa tsono akananga mune imwe ye ventricles yeuropi yako.
• Munguva yekudonha kwetangi, chiremba wako anoisa tsono kumashure kwehenya rako.
• Iyo ventricular shunt kana yekudonha inogona kuunganidza CSF kubva pombi inoiswa nachiremba wako muuropi hwako. Izvi zvinoitirwa kusunungura yakakwira fluid kumanikidza.

CSF muunganidzwa unowanzo kuve wakabatanidzwa nemamwe maitiro. Semuenzaniso, dhayi inogona kuiswa muCSF yako kune myelogram. Iyi iX-ray kana CT scan yehuropi hwako uye musana.

Ngozi dzekuputika kwechiuno

Uyu muedzo unoda kusunungurwa kwakasainwa uko kunoti iwe unonzwisisa njodzi dzeiyi nzira.

Njodzi dzekutanga dzinosanganisirwa nekupunzwa kwechiuno dzinosanganisira:

• kubuda ropa kubva panzvimbo yekubaya kupinda mumusana, izvo zvinonzi zvinorwadza pombi
• kusagadzikana panguva uye mushure mekuita
• sema seyakaitika kune iyo anesthetic
• hutachiona panzvimbo yekubaya
• kurwadziwa nemusoro mushure mekuedzwa

Vanhu vanotora vanoonda ropa vane njodzi yakakura yekubuda ropa. Lumbar puncture ine njodzi zvakanyanya kune vanhu vane matambudziko ekugwamba akadai seplatelet count shoma, inonzi thrombocytopenia.

Kune njodzi dzakakomba dzekuwedzera kana iwe uine hura hwehuropi, bundu, kana abscess. Aya mamiriro anoisa kumanikidza pane yako tsinga stem. Lumbar puncture inogona kukonzera uropi herniation kuitika. Izvi zvinogona kukonzera kukuvara kwehuropi kana kutofa.

Brain herniation iko kuchinjika kwezvivakwa zvehuropi. Kazhinji inofambidzana nepamusoro yekumanikidza kushushikana. Mamiriro acho anozopedzisira abvisa ropa kuuropi yako. Izvi zvinokonzeresa kukuvara kusingagadzirisike. Muedzo hauzoitwe kana hura hwehuropi hunofungidzirwa.

Matangi uye evirosi nzira yekurova ine dzimwe njodzi. Idzi njodzi dzinosanganisira:

• kukuvara kumuzongoza wako kana uropi
• kubuda ropa mukati meuropi hwako
• kukanganisa kweropa-brain barriers

Nei muyedzo wakarairwa

CSF ongororo inogona kurairwa kana iwe uine CNS kushungurudzika. Inogona zvakare kushandiswa kana iwe uine gomarara uye chiremba wako achida kuona kana gomarara rapararira kuCNS.

Uye zvakare, CSF ongororo inogona kurairwa kana iwe uine chimwe kana zvimwe zvezvinotevera zviratidzo.

• yakaoma, isingaregi kutemwa nemusoro
• mutsipa wakaoma
• kufungidzira, kuvhiringidzika, kana kuora mwoyo
• pfari
• furu-kunge zviratidzo zvinoramba zvichikura
• kuneta, kuneta, kana kushaya simba kwemhasuru
• shanduko mukuziva
• kusvotwa kwakanyanya
• fivha kana mapundu
• chiedza chekunzwa
• chiveve kana kudedera
• dzungu
• kutaura matambudziko
• kunetseka kufamba kana kusabatana zvakanaka
• kushushikana kwakanyanya
• isingachinjiki kiriniki kuora mwoyo

Zvirwere zvakaonekwa neCSF ongororo

CSF ongororo inogona kunyatso kusiyanisa pakati penzvimbo dzakasiyana siyana dzezvirwere zveCNS izvo zvingave zvakaoma kuti zvionekwe. Mamiriro ezvinhu akawanikwa neCSF ongororo anosanganisira:

Zvirwere zvinotapukira

Mavairasi, mabhakitiriya, fungi, uye zvipembenene zvinogona kukanganisa CNS. Humwe hutachiona hunogona kuwanikwa neCSF ongororo. Kazhinji hutachiona hweCNS hunosanganisira:

• yomumuzongoza
• encephalitis
• tibhii
• fungal zvirwere
• Utachiona hweWest Nile
• Eastern equine encephalitis virus (EEEV)

Hemorrhaging

Intracranial kubuda ropa kunogona kuonekwa neCSF kuongororwa. Nekudaro, kupatsanura chaiko kunokonzera kubuda ropa kungangoda mamwe ma scan kana bvunzo. Zvinowanzoitika zvinosanganisira kukwirisa kweropa, sitiroko, kana aneurysm.

Matambudziko ekudzivirira immune

CSF ongororo inogona kuona immune mhinduro kusagadzikana. Iyo immune system inogona kukonzera kukuvara kune iyo CNS kuburikidza nekuzvimba, kuparadzwa kweiyo myelin sheath kutenderedza tsinga, uye antibody kugadzirwa.

Zvirwere zvakajairika zverudzi urwu zvinosanganisira:

• Guillain-Barré chirwere
• sarcoidosis
• neurosyphilis
• multiple sclerosis

Mamota

CSF ongororo inogona kuona ekutanga mamota muuropi kana musana. Inogona zvakare kuona metastatic kenza yakapararira kune yako CNS kubva kune dzimwe nhengo dzemuviri.

CSF kuongorora uye multiple sclerosis

CSF ongororo inogona zvakare kushandiswa kubatsira kuongorora yakawanda sclerosis (MS). MS chirwere chisingaperi umo immune system yako inoparadza chifukidzo chekudzivirira chemitsipa yako, inonzi myelin. Vanhu vane MS vanogona kuve nezviratidzo zvakasiyana siyana zvinogara zvichiuya kana kuuya nekuenda. Zvinosanganisira chiveve kana kurwadziwa mumaoko avo nemakumbo, matambudziko ekuona, uye kunetseka kufamba.

CSF ongororo inogona kuitwa kutonga kunze kweimwe mamiriro ekurapa ayo ane zviratidzo zvakafanana neMS. Iyo fluid inogona kuratidzawo zviratidzo zvekuti immune system yako haisi kushanda zvakajairika. Izvi zvinogona kusanganisira mazinga epamusoro eIgG (mhando yema antibody) uye kuvepo kwemamwe mapuroteni anoita apo myelin inodonha. Vanenge makumi masere nemakumi mapfumbamwe kusvika makumi mapfumbamwe muzana vevanhu vane MS vane izvi zvisina kujairika muhuropi hwavo hwemuzongoza.

Dzimwe mhando dzeMS kufambira mberi nekukurumidza uye dzinogona kutyisidzira hupenyu mukati memavhiki kana mwedzi. Kutarisa mapuroteni ari muCSF kunogona kuita kuti vanachiremba vagadzire "makiyi" anonzi biomarkers. Biomarkers inogona kubatsira kuziva mhando yeMS yauinayo pakutanga uye nyore. Kuongororwa kwekutanga kunogona kukubvumidza iwe kuti uwane kurapwa kunogona kuwedzera hupenyu hwako kana uine fomu yeMS iri kukurumidza kufambira mberi.

Lab kuyedza uye kuongorora kweCSF

Izvi zvinotevera zvinowanzo kuyerwa mu CSF ongororo:

• machena masero eropa
• tsvuku masero eropa kuverenga
• chloride
• shuga, kana shuga yeropa
• glutamine
• lactate dehydrogenase, inova enzyme yeropa
• mabhakitiriya
• maantigen, kana zvinhu zvinokuvadza zvinogadzirwa nehutachiona hunopinda
• mapuroteni akazara
• oligoclonal mabhendi, ayo akasarudzika mapuroteni
• gomarara maseru
• hutachiona DNA
• masoja anorwisa hutachiona

Kududzira bvunzo dzako

Zvakajairwa mhedzisiro zvinoreva kuti hapana chisina kujairika chakawanikwa mu spinal fluid. Ese matanho akayerwa ezve CSF akawanikwa ari mukati meyakajairika renji.

Mhedzisiro isina kujairika inogona kukonzerwa neimwe yeanotevera:

• bundu
• kenza yemastastatic
• kubuda ropa
• encephalitis, kunova kuzvimba kwehuropi
• chirwere
• kuzvimba
• Reye's syndrome, inova isingawanzo, kazhinji inouraya chirwere inobata vana vane hukama nehutachiona hwehutachiona uye kumedza aspirin
• meningitis, iyo iwe yaunowana kubva kune fungi, tibhii, hutachiona, kana bhakitiriya
• hutachiona hwakadai seWest Nile kana Eastern equine
• Guillain-Barré syndrome, inova autoimmune mamiriro inokonzeresa kuora mitezo uye inoitika mushure mekuratidzwa kwehutachiona
• sarcoidosis, inova granulomatous mamiriro echikonzero chisingazivikanwe chinokanganisa nhengo zhinji (kunyanya mapapu, mapfundo, uye ganda)
• neurosyphilis, inoitika kana hutachiona ne syphilis hunosanganisira huropi hwako
• multiple sclerosis, inova autoimmune kusagadzikana kunokanganisa uropi hwako uye musana

Kutevera mushure mekuongorora kweCSF

Yako yekutevera uye maonero anoenderana nezvinokonzeresa kuti yako CNS bvunzo ive isina kujairika. Kuenderera mberi nekuyedza kungangodikanwa kuitira kuti uwane chaiyo kuongororwa. Kurapa uye mhedzisiro zvichasiyana.

Meningitis inokonzerwa nehutachiona kana hutachiona hutachiona chirwere chekukurumidzira. Zviratidzo zvakafanana nehutachiona hwemenosis. Nekudaro, hutachiona hwehutachiona hwenhumbu hautyisidzi hupenyu.

Vanhu vane bacterial meningitis vanogona kupihwa yakafara-masystem maantibhakitiriya kusvikira chikonzero chehutachiona chatemwa. Kukurumidza kurapwa kwakakosha kuchengetedza hupenyu hwako. Inogona zvakare kudzivirira zvachose CNS kukuvara.