Dermatitis Herpetiformis uye Gluten Kusashivirira
Zvemukati
- Mifananidzo yedermatitis herpetiformis
- Chii chinokonzera dermatitis herpetiformis?
- Ndiani ari panjodzi yedermatitis herpetiformis?
- Ndezvipi zviratidzo zve dermatitis herpetiformis?
- Dermatitis herpetiformis inoonekwa sei?
- Ndeapi marapirwo anowanikwa kune dermatitis herpetiformis?
- Ndeapi matambudziko e dermatitis herpetiformis?
- Ndeipi iyo yakareba-tarisiro ye dermatitis herpetiformis?
Chii chinonzi dermatitis herpetiformis?
Iko kunhuwa, kuputika, kupisa ganda kuputika, dermatitis herpetiformis (DH) mamiriro akaoma kugara nawo. Rash nekurumwa kunoitika pamaoko, mabvi, ganda romusoro, musana, uye magaro. Uku kupenga kunogona kuratidza kusagadzikana kweguteni, iyo inogona kunge iine hukama neyakaipisisa mamiriro ezvinhu anozivikanwa sechirwere chechiliac. DH dzimwe nguva inonzi chirwere cheDuhring kana kuputika kweguteni. Vanhu vane chirwere ichi vanofanirwa kuchengetedza yakasimba-isina kudya kweguteni.
Mifananidzo yedermatitis herpetiformis
Chii chinokonzera dermatitis herpetiformis?
Kubva kurira kwezita, vanhu vazhinji vanofunga kuti kupenga uku kunokonzerwa neimwe nzira yeherpes hutachiona. Izvi hazvisizvo, sezvo zvisina chekuita neherpes. Dermatitis herpetiformis inowanikwa mune vanhu vane chirwere ichi. Chirwere cheCeliac (chinonziwo celiac sprue, kusagadzikana kweguteni, kana gluten-sensitive enteropathy) chirwere chemuviri chinoratidzirwa nekusashivirira kune gluten. Gluten ipuroteni inowanikwa mugorosi, rye uye bhari. Izvo zvakare dzimwe nguva inowanikwa muoats akagadziriswa muzvirimwa zvinobata zvimwe zviyo.
Sekureva kweNational Institutes of Health (NIH), 15 kusvika 25 muzana yevanhu vane chirwere ichi vane DH. Chirwere cheCeliac chinogona kukonzeresa kurwadziwa kwepamuviri, kuzvimbirwa, kusvotwa, uye kurutsa. Vanhu vane DH havawanzove nezviratidzo zvemukati. Zvisinei, kunyange kana vasina kuwana zviratidzo zvemukati, makumi masere kubva muzana kana kupfuura vanhu vane DH vachiri kukuvara kwematumbo, kunyanya kana vachidya chikafu chakazara mu gluten, maererano neNational Foundation yeCeliac Awareness (NFCA).
Iko kukuvara kwemukati uye kuputika kunokonzerwa nekuita kweprotein mapuroteni ane yakasarudzika mhando yeanorwisa muviri inonzi immunoglobulin A (IgA). Muviri wako unoita maAgA antibodies kurwisa mapuroteni e gluten. Kana masoja eIga akarwisa gluten, anokuvadza zvikamu zvematumbo zvinokutendera kuti utore mavitamini uye zvinovaka muviri. Uku kunzwisisika kune gluten kunowanzo mhanya mumhuri.
Izvo zvivakwa zvinoumbwa apo IgA inonamatira kune gluten ndokuzopinda muropa, uko kwavanotanga kuvhara tsinga dzeropa diki, kunyanya idzo dziri muganda. Masero machena eropa anokwezva kune aya mavhagi. Masero eropa machena anoburitsa kemikari inonzi "mukwanisi" iyo inokonzeresa kupenya, blistery rash.
Ndiani ari panjodzi yedermatitis herpetiformis?
Chirwere cheCeliac chinogona kubata chero munhu, asi chinowanzo kuve chinowanzoitika kune vanhu vane imwe nhengo yemhuri ine chirwere chechiliac kana DH.
Kunyangwe vakadzi vazhinji kupfuura varume vachiwanikwa vaine chirwere chechiliac, varume vanowanzoita DH kupfuura vakadzi, sekureva kweNIH. Rash kazhinji inotanga muma20s kana makumi matatu, kunyangwe ichikwanisa kutanga muhudiki. Mamiriro acho anowanzoitika kune vanhu vanobva kuEurope. Izvo zvishoma zvinowanzo bata vanhu vedzinza reAfrica kana Asia.
Ndezvipi zviratidzo zve dermatitis herpetiformis?
DH ndeimwe yeakanyanya kupusa kunogoneka. Nzvimbo dzakajairika dzekumhanyisa dzinosanganisira:
- magokora
- mabvi
- kudzika kumashure
- bvudzi
- kumashure kwemutsipa
- mapepa
- magaro
- ganda romusoro
Iwo mapundu anowanzoenzana saizi uye chimiro pamativi ese emuviri uye kazhinji anouya uye anoenda.
Pamberi pekuputika kwakazara kweiyo rash, iwe ungangonzwa ganda munzvimbo ine rash-yakakomberedza kupisa kana kutsva. Mapundu anotaridzika kunge mapundu azere nemvura yakajeka anotanga kuumbika. Izvi zvinokurumidza kukwenya. Mapundu anopora mukati memazuva mashoma uye anosiya mucherechedzo wepepuru unogara kwemavhiki. Asi mapundu matsva anoenderera mberi achiumbwa apo zvekare zvinopora. Maitiro aya anogona kuenderera kwemakore, kana anogona kupinda mukuregererwa obva adzoka.
Kunyange zviratidzo izvi zvinowanzo kuve zvine chekuita nedermatitis herpetiformis, zvinogona kukonzereswa nemamwe mamiriro eganda senge atopic dermatitis, inogumbura kana yeergergia inosangana nedermatitis, psoriasis, pemphigoid, kana scabi.
Dermatitis herpetiformis inoonekwa sei?
DH inonyanya kuongororwa ine ganda biopsy. Chiremba anotora kamuenzaniso keganda ndokuriongorora pasi pe microscope. Dzimwe nguva, yakananga immunofluorescence bvunzo inoitwa, umo ganda rakakomberedza rash rakasvibiswa nedhayi iyo inoratidza kuvepo kweIgA antibody deposits. Iyo biopsy yeganda inogona zvakare kubatsira kuona kana izvo zviratidzo zvinokonzerwa neimwe mamiriro eganda.
Kuongororwa kweropa kuti utarise ma antibodies muropa kunogona kuitwawo. Chirwere chemukati chinogona kuitwa kuti chisimbise kuvepo kwekukuvara nekuda kwechirwere chechiliac.
Kana chirwere ichi chisina chokwadi, kana kumwe kuongororwa kuchikwanisika, kumwe kuongororwa kunogona kuitwa. Patch kuyedza ndiyo nzira yakanakisa yekuongorora yeergergic kuonana dermatitis, inova chikonzero chinowanzoitika chezviratidzo zvakafanana nedermatitis herpetiformis.
Ndeapi marapirwo anowanikwa kune dermatitis herpetiformis?
DH inogona kurapwa nemishonga inorwisa mabhakitiriya inonzi dapsone. Dapsone mushonga une simba une zvakakomba mhedzisiro. Muyero unofanirwa kuwedzerwa zvishoma nezvishoma pamusoro pemwedzi yakati wandei usati wanyatsoshanda.
Vazhinji vanhu vanoona zororo kubva pakutora dapsone, asi mhedzisiro inogona kusanganisira:
- matambudziko echiropa
- kunzwisiswa nechiedza chezuva
- kupererwa neropa
- kushaya simba kwetsandanyama
- peripheral neuropathy
Dapsone inogona zvakare kuve nekudyidzana kwakashata nemimwe mishonga, senge aminobenzoate potasium, clofazimine, kana trimethoprim.
Mimwe mishonga inogona kushandiswa inosanganisira tetracycline, sulfapyridine, uye mimwe mishonga yekuzvidzivirira. Izvi hazvishande zvakanyanya kupfuura dapsone.
Mushonga unonyanya kushanda uyo usina mhedzisiro ndeyekuomerera zvakanyanya kune isina-gluten kudya. Izvi zvinoreva kuti unofanirwa kudzivirira zvachose chikafu, chinwiwa, kana mishonga ine zvinotevera:
- gorosi
- rye
- bhari
- oats
Kunyangwe chikafu ichi chichive chakaoma kutevera, chichava nemhedzisiro inobatsira pahutano hwako kana uine chirwere checliac. Chero kudzikiswa kwekudya kweguteni kunogona kubatsira kudzikisa huwandu hwemishonga iwe yauchazoda kutora.
Ndeapi matambudziko e dermatitis herpetiformis?
Vanhu vane chirwere chisina kubatwa cheDH uye chechiliac vanogona kuve nenjodzi yakakwira yekenza yemudumbu nekuda kwekuramba uchizvimba mumatumbu. Kushomeka kwevhitamini uye kupererwa neropa kunogona zvakare kuve dambudziko kana ura husiri kutora zvinovaka muviri.
Sezvo DH iri chirwere che autoimmune, chawana kuti icho chinosanganisirwa nemamwe marudzi akasiyana ezvirwere zve autoimmune. Izvi zvinosanganisira:
- hypothyroidism
- vitiligo
- mhando 1 chirwere cheshuga mellitus
- myasthenia gravis
- Sjögren's chirwere
- rheumatoid arthritis
Ndeipi iyo yakareba-tarisiro ye dermatitis herpetiformis?
DH chirwere cheupenyu hwese. Iwe unogona kupinda mukuregererwa, asi chero nguva iwe paunosangana ne gluten, unogona kuve nekuputika kwekuputika. Pasina kurapwa, DH uye chirwere chechiliac chinogona kukonzera mhedzisiro yakawanda yakaipa, kusanganisira kushomeka kwevhitamini, kupererwa neropa, uye gomarara remudumbu.
Kurapa ne dapsone kunogona kudzora iyo yekumhanyisa zviratidzo panzvimbo nekukurumidza. Nekudaro, kukuvara kwemukati kunokonzerwa nechirwere chechiliac kunogona kurapwa chete nekuchengetedza yakasimba-isina kudya kweguteni. Ita shuwa yekukurukura chero chaiwo maratidziro ezvekudya nachiremba wako kana wezvehutano.