Acromegaly uye gigantism: zviratidzo, zvinokonzera uye kurapwa

Zvemukati

• Zviratidzo zvikuru
• Ndeapi matambudziko
• Maitiro ekusimbisa kuongororwa
• Kurapwa kunoitwa sei

Gigantism chirwere chisingawanzoitika icho muviri unoburitsa yakawandisa mahormone, ayo anowanzo kuve nekuda kwekuvapo kwechunhu bundu mune iyo pituitary gland, inozivikanwa sepituitary adenoma, ichikonzera mitezo uye zvikamu zvemuviri kukura kukura kupfuura zvakajairwa.

Kana chirwere chikamuka kubva pakuzvarwa, chinozivikanwa se gigantism, zvisinei, kana chirwere chikamuka mukukura, kazhinji chakatenderedza makore makumi matatu kana makumi mashanu, chinozivikanwa seacromegaly.

Muzviitiko zvese izvi, chirwere chinokonzereswa neshanduko yepituitary gland, nzvimbo yehuropi iyo inoburitsa mahormone ekukura, uye nekudaro kurapwa kunoitwa kudzikisa kugadzirwa kwehomoni, uko kunogona kuitwa kuburikidza nekuvhiyiwa., Kushandiswa kwemishonga kana radiation, Semuyenzaniso.

Zviratidzo zvikuru

Vakuru vane acromegaly kana vana vane gigantism vanowanzove neakakura kupfuura akajairwa maoko, tsoka nemiromo, pamwe neakakora kumeso maficha. Mukuwedzera, kuwedzera kukura kwehomoni kunogona kukonzera:

• Kuchenesa kana kupisa mumaoko nemakumbo;
• Glucose yakawandisa muropa;
• Kumanikidza kukuru;
• Kurwadziwa uye kuzvimba mumajoini;
• Kuona kaviri;
• Yakawedzerwa mandible;
• Shanduko mu locomotion;
• Kukura kwemutauro;
• Late kuyaruka;
• Zvisina kujairika kumwedzi;
• Kuneta zvakanyanya.

Uye zvakare, sezvo paine mukana wekuti kuwanda kwekukura kwehomoni kuri kugadzirwa nechunhu bundu mune iyo pituitary gland, zvimwe zviratidzo senge zvinowanzoitika kutemwa nemusoro, matambudziko ekuona kana kudzikira chishuwo chebonde, semuenzaniso, zvinogona zvakare kumuka.

Ndeapi matambudziko

Zvimwe zvezvinetso zvinogona kuunzwa nemurwere kumurwere ndeizvi:

• Chirwere cheshuga;
• Kurara kufema;
• Kurasikirwa kwemaonero;
• Yakawedzera saizi yemoyo;

Nekuda kwenjodzi yematambudziko aya, zvakakosha kuenda kuna chiremba kana uchifungidzira kuti chirwere ichi kana shanduko yekukura.

Maitiro ekusimbisa kuongororwa

Kana paine fungidziro yekuti une gigantism, kuongororwa kweropa kunofanirwa kuitwa kuyera mazinga eIgf-1, puroteni inowedzerwa kana huwandu hwehormone hwekukura hwave pamusoro pechinyakare, zvichiratidza acromegaly kana gigantism.

Mushure mekuongorora, kunyanya kana ari munhu mukuru, CT scan inogona zvakare kurairwa, semuenzaniso, kuti uone kana paine bundu mupituitary gland iro rinogona kunge richichinja mashandiro aro. Mune zvimwe zviitiko, chiremba anogona kuraira kuyerwa kwekukura kwehomoni kuwanda.

Kurapwa kunoitwa sei

Kurapa kwe gigantism kunosiyana zvichienderana nezviri kukonzera kukura kwakanyanya kemikari. Nekudaro, kana paine bundu mune iyo pituitary gland, inowanzo kukurudzirwa kuvhiyiwa kubvisa bundu uye kudzoreredza chaiyo kugadzirwa kwemahormone.

Nekudaro, kana pasina chikonzero chekuti pituitary basa rishanduke kana kana kuvhiya kusingashande, chiremba anogona kungoratidza kushandiswa kwemwaranzi kana mishonga, senge somatostatin analogs kana dopamine agonists, semuenzaniso, iyo inofanira kushandiswa mukati mehupenyu hwese. kuchengetedza mahormone pasi pesimba.