Hypoparathyroidism: chii, zviratidzo uye kurapwa

Zvemukati

• Zviratidzo zvikuru
• Kurapwa kunoitwa sei
• Possible zvikonzero hypoparathyroidism
• Zvikonzero zvekutanga hypoparathyroidism
• Zvinokonzera yechipiri hypoparathyroidism
• Zvinokonzera pseudohypoparathyroidism

Hypoparathyroidism inoreva kune seti yezvirwere, kana mamiriro ezvinhu, ayo anotungamira mukudzikira kwekuita kwehomoni PTH, inozivikanwawo separathormone.

Iyi kemikari inogadzirwa neparathyroid gland, ayo ari mana madiki madiki ari kuseri kwetachiona uye ihomoni yakakosha iyo, pamwechete ne vhitamini D, inochengeta yakakwana calcium mazinga muropa.

Nekudaro, kana paine kushomeka kwePTH mumuviri, zvakajairika kuona kudzikira kwemazinga ecalcium muropa, inozivikanwa se hypocalcemia, iyo inogona kukonzeresa zviratidzo senge kushaya simba, mhasuru spasms, shanduko mumapfupa, matambudziko emitsipa. kana kunyange matambudziko emwoyo. Dzidza zvakawanda nezve hypocalcemia uye zvazvinogona kukonzeresa.

Zviratidzo zvikuru

Zviratidzo zve hypoparathyroidism zvakanyanya zvine chekuita nematambudziko anokonzerwa nekusaita basa kwePTH. Nekudaro, zvimwe zviratidzo nezviratidzo zvinogona kumuka zvinosanganisira:

• Simba rakasimba tsandanyama;
• Tsandanyama mhasuru;
• Tsvina kushaya simba kana kurwadziwa;
• Kubata kwepasi;
• Mwoyo palpitations

Sezvo PTH iri calcium-inogadzirisa mahormone, kana isina kukwana PTH, calcium haigone kunyudzwa mushe uye ichiri kubviswa mumuti, zvichitungamira kumatunhu akadzika ecalcium muropa kana hypocalcemia.

Iko kusimba kwezviratidzo zvinoenderana nekuomarara uye nekukurumidza kwekurasikirwa kwecalcium mazinga. Varwere vazhinji vane hypoparathyroidism vane asymptomatic, uye vanongova nezviratidzo kana paine kudiwa kwe calcium yakawanda mumuviri, senge panguva yekuzvitakura, kuyamwisa kana nekushandisa kwemishonga inoderedza calcium.

Mune zvimwe zviitiko zvisingaperi uye zvakapfava, panogona kunge pasina zviratidzo, uye chirwere ichi chinongowanikwa mukuyedzwa kwenguva dzose, kana panogona kunge paine zviratidzo zvakapfava sekugwinha uye kushaya kwekunzwa mutsoka, maoko kana kutenderedza muromo.

Kurapwa kunoitwa sei

Kurapa kwehypoparathyroidism kune chinangwa chikuru chekudzora kuderera kwecalcium mumuviri, uye kunofanirwa kutungamirwa neye endocrinologist zvinoenderana nechikonzero chayo, kuomarara, zviratidzo uye neropa calcium mazinga.

Kana huwandu hwecalcium hwakadzikira kwazvo, pazasi pe7.5mg / dl, hypocalcemia yakaoma inoonekwa uye, mune idzi kesi, kurapwa muchipatara kunodiwa, nekasiamu kutsiva yakananga mutsinga, ine calcium gluconate.

Kana hypocalcemia iri nyoro uye isingaperi, kurapwa kunosanganisira kutsiva calcium uye vhitamini D nemuromo. Magnesium inobatsira kukurudzira kugadzirwa kwePTH uye, nekudaro, inogona kubatsira, kunyanya kana iwo mazinga ari zvakare akaderera. Mimwe mishonga, senge thiazide diuretics kana kutsiva kwePTH inodzokororazve, inogona kupihwa zano neiyo endocrinologist, zvichienderana nenyaya imwe neimwe.

Possible zvikonzero hypoparathyroidism

Hypoparathyroidism inogona kuganhurwa mumhando mbiri mbiri, zvinoenderana nezvikonzero zvinotungamira mukusaita kwePTH:

• Chikuru hypoparathyroidism: kunoitika kana kugadzirwa kwePTH kukanganisika nekuti maronda ane dambudziko kana kuti abviswa.
• Sekondari hypoparathyroidism: ndipo apo kumwe kukurudzira, kwakadai senge yakaderera magnesium, kunokonzeresa kuti gland dziite PTH shoma isina dambudziko mavari.

Kune zvekare nyaya yechitatu, inonzi pseudo-hypoparathyroidism, inoitika muzvirwere zvakagarwa nhaka, ndiko kuti, inopfuura nemajini emhuri, kubva kuvabereki kuenda kuvana, uye izvo zvinowedzera kupokana munhengo dzinofanirwa kuita mahormone. Nekudaro, iyo mahormoni haigone kuita basa rayo kunyangwe iri kuburitswa muhuwandu hwakaringana nezvirwere zveparathyroid.

Zvikonzero zvekutanga hypoparathyroidism

Rudzi urwu runowanzoitika nguva zhinji nekuda kwekubviswa kwezvipenga zveparathyroid, mune zviitiko zvekurapwa kwehyperparathyroidism, semuenzaniso, asi zvinogona zvakare kuitika nekuda kwekukuvara netsaona kuzvipenga zveparathyroid. Iyi kesi inoitika kana kuvhiya kwaitwa padunhu remutsipa, kureva iyo thyroid, yekenza kana maqhumu. Sezvo zvivakwa zviri padyo uye magemenzi ari madiki kwazvo, dzimwe nguva zvinonetsa kuaziva nekuzvitsaura kubva kune zvimwe zvivakwa. Tarisa uone kuti kubvisa utachiona kunokosha sei uye kuti kupora kwakadii.

Zvinokonzera yechipiri hypoparathyroidism

Rudzi urwu rwe hypoparathyroidism runowanzo kukonzerwa nekushomeka kwemagesium inoenderera.

Kunyangwe iyo yakaderera magnesium inogona kukurudzira kugadzirwa kwePTH, apo iyo magnesium iri yakadzika kwazvo, uye kwenguva yakareba, inotumira meseji kune iyo parathyroid kuti isaburitse yakawanda PTH uye ichiri kuita kuti nhengo dzive dzisina hanya nehormone, kuti iyo haigone kuita, ichikonzera hypoparathyroidism.

Zvinokonzera pseudohypoparathyroidism

Pseudo-hypoparathyroidism inoreva seti yezvirwere umo majini, kazhinji nhaka, anokonzeresa kuti nyama dzemuviri dzisave nehanya nekuita kwePTH. Kune matatu marudzi epseudohypoparathyroidism, zvinoenderana nekuti ane hukama here nechirwere chisingawanzo chinonzi Albright's hereditary osteodystrophy uye nemhando yekudzivirira kwePTH kunokonzerwa.

Mukupindura kushomeka kwechiito chePTH, maronda anowedzera muhukuru uye anoedza kuburitsa yakawanda PTH, neyakajairika kana kunyange yakakwira PTH mazinga muropa, asi iyi PTH haigone kuita. Naizvozvo, iyo kiriniki pikicha yakafanana neiyo hypoparathyroidism, sezvazviri sekunge iyo hormone yakanga isipo. Naizvozvo, haigone kudaidzwa kunzi hypoparathyroidism, nekuti pachokwadi kutenderera kwePTH kwakajairika kana kutowedzerwa, iko kunzi pseudo-hypoparathyroidism, zvinoreva kuti "zvakafanana ne hypoparathyroidism".