Immunotherapy seChipiri-Mutsetse Therapy yeiyo Isiri- Diki Cell Lung Cancer

Zvemukati

• Immunotherapy: Iyo inoshanda sei
• Checkpoint inhibitors yeNSCLC
• Ndeipi iwe yaunowana immunotherapy?
• Iwe unowana sei immunotherapy?
• Vanoshanda zvakadii?
• Ndeipi mhedzisiro?
• Tora woenda nazvo

Mushure mekunge maonekwa kuti mune isina-diki kenza yemapapu kenza (NSCLC), chiremba wako anozoenda pamusoro pesarudzo dzako dzekurapa newe. Kana iwe uine kenza yekutanga-danho, kuvhiyiwa kunowanzo kuve sarudzo yekutanga. Kana kenza yako yafambira mberi, chiremba wako anozoibata nekuvhiya, chemotherapy, radiation, kana mubatanidzwa wevatatu.

Immunotherapy inogona kuve yechipiri-mutsara kurapwa kweNSCL. Izvi zvinoreva kuti unogona kuve mukwikwidzi wemununotherapy kana mushonga wekutanga waunoyedza ukasashanda kana kumira kushanda.

Dzimwe nguva vanachiremba vanoshandisa immunotherapy sekurapa-mutsara wekutanga pamwe chete nemamwe madhiragi mukenza-yemberi gomarara rakapararira mumuviri wese.

Immunotherapy: Iyo inoshanda sei

Immunotherapy inoshanda nekusimudzira immune system yako kuwana uye kuuraya cancer maseru. Iyo immunotherapy mishonga inoshandiswa kurapa NSCLC inonzi checkpoint inhibitors.

Immune system yako ine uto remasero anouraya anonzi maT seli, ayo anovhima gomarara nemamwe maseru ekune dzimwe nyika anotyisa nekuaparadza Checkpoints mapuroteni ari pamusoro pemasero. Ivo vanoita kuti maT cell azive kana sero rine hushamwari kana kukuvadza. Nzvimbo dzekutarisa dzinochengetedza maseru ane hutano nekudzivirira immune system yako kubva pakuwedzera kurwisa kwadzo.

Cancer maseru anogona dzimwe nguva kushandisa aya ekuongorora kuvanda kubva kuzvirwere zvemuviri. Checkpoint inhibitors inovhara cheki chekuongorora mapuroteni kuitira kuti masero eT agone maseru ekenza uye aaparadze. Chaizvoizvo, mishonga iyi inoshanda nekubvisa mabhureki pamhinduro yemasoja ekudzivirira chirwere chegomarara.

Checkpoint inhibitors yeNSCLC

Mane immunotherapy zvinodhaka zvinorapa NSCLC:

• Nivolumab (Opdivo) uye pembrolizumab (Keytruda)
  bvisa puroteni inonzi PD-1 pamusoro peT seli. PD-1 inodzivirira T masero
  kubva pakurwisa kenza. Kuvharira PD-1 inobvumira immune system kuti ivhime
  uye kuparadza masero ekenza.
• Atezolizumab (Tecentriq) uye durvalumab
  (Imfinzi) vharira imwe protein inonzi PD-L1 pamusoro pematumbo maseru uye
  masero ekudzivirira muviri. Kuvhara protein iyi zvakare kunosunungura mhinduro yemumuviri kurwisa
  gomarara.

Ndeipi iwe yaunowana immunotherapy?

Vanachiremba vanoshandisa Opdivo, Keytruda, uye Tecentriq seyechipiri-mutsara kurapa. Iwe unogona kuwana imwe yemishonga iyi kana kenza yako yatanga kukura zvakare mushure memakemikari ekurapa kana kumwe kurapwa. Keytruda inopihwawo semutsetse wekutanga kurapwa kweanononoka-nhanho NSCLC, pamwe nekemotherapy.

Imfinzi ndeyevanhu vane stage 3 NSCLC vasingakwanise kuvhiyiwa, asi vane gomarara harina kunyanya kuipa mushure memakemikari nemwaranzi. Inobatsira kumisa kenza kubva mukukura kwenguva yakareba sezvinobvira.

Iwe unowana sei immunotherapy?

Immunotherapy madhiragi anounzwa sekumunzwa kuburikidza nemutsipa paruoko rwako. Iwe unozowana izvi zvinodhaka kamwe chete pavhiki mbiri kana nhatu.

Vanoshanda zvakadii?

Vamwe vanhu vakaona zvinokatyamadza kubva kumaununotherapy madhiragi. Mushonga wacho wakadzvanya mamota avo, uye wamisa kenza kubva mukukura kwemwedzi yakawanda.

Asi havazi vese vanobvuma kurapwa uku. Gomarara rinogona kumira kwechinguva, uye rodzoka. Vatsvagiri vari kuyedza kudzidza kuti ndeipi kanzuru inopindura zvakanyanya kune immunotherapy, saka vanogona kunanga kurapwa uku kune vanhu vanozowana kubatsirwa kwanyanya nazvo.

Ndeipi mhedzisiro?

Zvakajairika mhedzisiro kubva kune immunotherapy zvinodhaka zvinosanganisira:

• kuneta
• kukosora
• kusvotwa
• kuvava
• mapundu
• kuda kudya
• kuvimbiswa
• manyoka
• kurwadza kwemajoini

Mimwe mhedzisiro yakakomba isingawanzoitika. Nekuti iyi mishonga inowedzera immune immune mhinduro, immune system inogona kutanga kurwisa kune dzimwe nhengo semapapu, itsvo, kana chiropa. Izvi zvinogona kuve zvakakomba.

Tora woenda nazvo

NSCLC kazhinji haina kuongororwa kusvikira yave padanho rekupedzisira, zvichiita kuti zvive zvakaoma kurapa nekuvhiya, chemotherapy, uye radiation. Immunotherapy yakavandudza kurapwa kwekenza iyi.

Checkpoint inhibitor zvinodhaka zvinobatsira kudzora kukura kweNCLCC yakapararira. Iyi mishonga haishande kune wese munhu, asi inogona kubatsira vamwe vanhu vane yekupedzisira-nhanho NSCLC kuenda mukuregererwa uye kurarama kwenguva refu.

Vatsvagidzi vari kudzidza nyowani immunotherapy mishonga mumakiriniki ekuedzwa. Tariro ndeyekuti mishonga mitsva kana mubatanidzwa mutsva wemishonga iyi nekemotherapy kana radiation inogona kusimudzira kupona zvakanyanya.

Kumbira chiremba wako kana mushonga weununotherapy wakakukodzera. Tsvaga kuti mishonga iyi ingavandudza sei kurapwa kwekenza, uye mhedzisiro ipi yavanogona kukonzera.