Neutropenia: chii uye chikuru zvikonzero

Zvemukati

• Zvinokonzera neutropenia
• Kutenderera neutropenia
• Febrile neutropenia

Neutropenia inowirirana nekuderera kwehuwandu hweyutrophils, ayo ari masero eropa anokonzera kurwisa hutachiona. Sezvineiwo, huwandu hwenyutrophiri hunofanira kunge huri pakati pe1500 ne8000 / mm³, zvisinei, nekuda kweshanduko yemongo kana mukukura kwemasero aya, huwandu hwekutenderera neutrophils hunogona kudzikira, hunoratidza neutropenia.

Maererano nehuwandu hweyutrophils yakawanikwa, neutropenia inogona kusarudzwa zvichienderana nekuomarara kwayo kuita:

• Nyoro neutropenia, uko neutrophils iri pakati pe1000 ne1500 / µL;
• Mwero neutropenia, mune iyo neutrophils iri pakati pe500 kusvika 1000 / µL;
• Yakakura neutropenia, mune iyo neutrophils isingasviki 500 / µL, iyo inogona kufarira kuwanda kwefungus uye mabhakitiriya anorarama zvakasikwa mumuviri, zvichikonzera hutachiona;

Izvo zvidiki huwandu hwekutenderera neutrophils, zvinowedzera mukana wemunhu kutapukirwa. Izvo zvakakosha kuti neutropenia inonyatso kuongororwa, sezvo mhedzisiro inogona kunge yakakonzerwa nematambudziko panguva yekuunganidza, sampuro yekuchengetera kana shanduko mumidziyo inoitwa ongororo, semuenzaniso. Naizvozvo, zvinokurudzirwa kuti iyo yakazara neutrophil kuverenga iongororwe kuona kana zvirizvo, pane neutropenia.

Pamusoro pezvo, kana huwandu hwamasero matsvuku eropa uye maplatelet ari akajairwa uye huwandu hweeutrophils hwakadzikira, zvinokurudzirwa kuti kuwanda kweropa kuitwe kuratidza neutropenia.

Zvinokonzera neutropenia

Iko kuderera kwehuwandu hweyutrophils kunogona kunge kuri nekuda kwekushomeka kwekugadzirwa kana shanduko mukukora kwemautrophil mumongo wemapfupa kana nekuda kwenzvimbo yepamusoro yekuparadzwa kweeutrophils muropa. Saka, zvikonzero zvikuru zveNeutropenia ndezvi:

• Megaloblastic kupererwa neropa;
• Aplastic kupererwa neropa;
• Leukemia;
• Yakawedzera spleen;
• Cirrhosis;
• Systemic lupus erythematosus;
• Paroxysmal nocturnal hemoglobinuria;
• Utachiona hutachiona, kunyanya nehutachiona hweEpstein-Barr uye hutachiona hwehepatitis;
• Hutachiona hwehutachiona, kunyanya kana paine tibhii uye septicemia.

Uye zvakare, neutropenia inogona kuitika semhedzisiro yekurapwa nemimwe mishonga, yakadai seAminopyrine, Propiltiouracil uye Penicillin, semuenzaniso, kana nekuda kwekushomeka kwevhitamini B12 kana folic acid, semuenzaniso.

Dzidza zvakawanda nezve neutrophils.

Kutenderera neutropenia

Cyclic neutropenia inoenderana neayo autosomal yakanyanya genetic chirwere chinoratidzwa nekudzikira kwenzvimbo dzema neutrophils mumatunhu, ndiko kuti, mazuva ese makumi maviri nerimwe, kazhinji yenguva, pane kuderera kwehuwandu hwekutenderera neutrophils.

Ichi chirwere hachiwanzoitika uye chinoitika nekuda kwekuchinja mune geni riripo pane chromosome 19 iyo inoitisa kugadzirwa kweiyo enzyme, elastase, mune neutrophils. Mukushaikwa kweiyo enzyme, neutrophils inowanzo kuparadzwa.

Febrile neutropenia

Febrile neutropenia inoitika kana paine mashoma neutrophils, kazhinji asingasviki 500 / µL, zvichifarira kuitika kwezvirwere uye zvichitungamira mukuwedzera kwekupisa kwemuviri, kazhinji pamusoro pe38ºC.

Naizvozvo, kurapwa kwefebrile neutropenia kunosanganisira kutora fivhiri-inoderedza mishonga, maantibiotic nemuromo kana kuburikidza nemutsinga, zvinoenderana nezvinoudzwa nachiremba kuti udzore hutachiona nemajekiseni ane neutrophil kukura zvinhu, kurwisa neutropenia. Uye zvakare, zvinogona zvakare kuve zvakafanira kuwedzera yechipiri antimicrobial pakurapa kana murwere achiramba aine fivha mushure memazuva mashanu ekutanga kurapwa.