5 Zvitsva Zvitsva Zvokurapa Zvinogona Kuderedza Kushandisa Opioid

Zvemukati

• Mazino Lasers
• Inononoka Kusunungura Yemunharaunda Anesthetics
• New C-Chikamu Tech
• Kuedzwa kweDNA
• Regenerative Medicine
• Ongororo ye

America iri pakati pedambudziko reopioid. Kunyangwe zvingasaratidzika kunge chimwe chinhu chaunofanirwa kuve nehanya nazvo, zvakakosha kuti uzive kuti vakadzi vanogona kuve nenjodzi yakakwira yekupindwa muropa neanorwadza, ayo anowanzo gadzirirwa mushure mekuvhiya kwese. Uye kunyangwe ivo vachishandiswa kurapa kurwadziwa kusingaperi zvakare, tsvagiridzo inoratidza kuti maopioid anogona kusabatsira kununura marwadzo munguva refu. Uyezve, asi havazi vese vanhu vanoshandisa maopioid vanova vakapindwa muropa, vazhinji vanoita, uye tarisiro yehupenyu yeU.S. yadzikira sezvo vanhu vazhinji vachifa neopioid overdoses.

Chikamu chakakura chekuyedza kurwisa denda iri ndechekutarisa kuti maopioid haadiwe uye kutsvaga mamwe marapirwo. Kunyange zvakadaro, vanachiremba vakawanda vanoomerera kuti opioid inokosha mune mamwe mamiriro ezvinhu anorwadza-zvose zvisingaperi uye zvakaoma. "Nekuti kurwadziwa kusingaperi kwakaomarara biopsychosocial mamiriro-zvichireva kuti zvinosanganisira kusangana kwehupenyu, hwepfungwa, uye zvemagariro - zvakasarudzika zvemunhu uye zvinokanganisa munhu wega zvakasiyana," anotsanangura Shai Gozani, MD, Ph.D., mutungamiri uye CEO pa NeuroMetrix. Opioids inodiwawo dzimwe nguva kana mumwe munhu aine kurwadziwa kwakanyanya, sekunge mushure mekuvhiyiwa kana kukuvara. "Tichifunga kuti marwadzo ichiitiko chemunhu, nzira dzekurapa dzinoda kuve munhu." Dzimwe nguva, izvo zvinosanganisira kushandiswa kweopioid, uye dzimwe nguva hazvidaro.

Nyanzvi dzinobvumirana kuti kune dzimwe nzira dzakawanda marwadzo anogona kurapwa anotakura nengozi shoma yekupindwa muropa. Zvinoenda pasina kutaura kuti kurapa kwemuviri, mamwe marapirwo ekurapa senge acupuncture, uye kunyangwe psychotherapy inogona kubatsira kuderedza kushandiswa kwemaopioid, asi imwe mutsara wedziviriro kurwisa denda reopioid ndiyo iri kubuda matekinoroji ari kuitwa akakwana uye achiwedzera kugamuchirwa. Heano mashanu ayo anogona kubatsira kudzora kushandisa opioid.

Mazino Lasers

Kutsvagurudza kunoratidza kuti vanhu kazhinji vane mishonga yekurwadziwa inosara mushure mekuvhiyiwa nemuromo, sehungwaru kuburitsa zino, izvo zvinosiya musuwo wakavhurika wekushandisa kwayo zvisizvo. Paunofunga kuti pamusoro pe90 muzana yevarwere vane zvakajairika kuvhiyiwa mukanwa (funga: kubvisa mazino, kuvhiya gum kunosanganisira stitches) zvinonyorerwa maopioid, sekureva kwaRobert H.Gregg, DDS, mubatsiri-akatanga weMillennium Dental Technologies uye Institute for Advanced Laser Dentistry, ndiyo mhando yechiitiko chikuru.

Ndicho chikamu chekuti nei akagadzira iyo LANAP laser, iyo inogona kushandiswa kuita kuvhiya kwemazino uye kunoderedza marwadzo, kubuda ropa, uye nguva yekupora. Dr. Gregg vanoti varwere vanosarudza iyo laser sarudzo vanongopihwa maopioid 0.5 muzana yenguva-musiyano mukuru.

Parizvino, ma lasers ari kushandiswa mumahofisi emazino e2,200 akasiyana-siyana munyika yose, uye Dr. Gregg anoti anotarisira kuti nhamba iyoyo ichakura zvishoma nezvishoma sezvo vanhu vachidzidza zvakawanda nezve laser dentistry uye kunzwisisa kuderera kwekuraira maopioid ekuvhiyiwa kwemuromo.

Inononoka Kusunungura Yemunharaunda Anesthetics

Aya marudzi emishonga anga aripo kwemakore akati wandei, asi ari kuwedzera kupihwa pamhando dzakasiyana siyana dzekuvhiya. Iyo inowanzozivikanwa inonzi Exparel, inova inononoka kuburitsa fomu yeanesthetic yemuno inonzi bupivacaine. “Mushonga unobata chiveve kwenguva refu unobaiwa mukati mekuvhiyiwa unogona kudzora marwadzo kwemazuva mashomanana okutanga pashure pokuvhiyiwa, apo varwere vanenge vachida zvikuru,” anotsanangura kudaro Joe Smith, M.D., chiremba wokutindivadza paInova Loudon Hospital muLeesburg, Virginia. "Izvi zvinoderedza, kana mune zvimwe zviitiko zvinobvisa, kudikanwa kwemaopioid. Izvi hazvisi izvo chete zvinobatsira varwere kuti vadzivise njodzi iri pachena yekuzvimirira, asi zvakare mhedzisiro yemhedzisiro senge kufema kushushikana, kusvotwa uye kurutsa, kuzvimbirwa, dzungu uye kuvhiringidzika, kungodoma vashoma. "

Chimwe chezvinhu zvakanakisisa pamusoro pemhinduro iyi ndeyokuti inogona kushandiswa kune marudzi akawanda akasiyana-siyana ekuvhiyiwa, kusanganisira kuvhiyiwa kwemapfupa akadai sekuvhiyiwa kwepafudzi, kugadzirisa ACL, nezvimwe zvakawanda, Dr. Smith anoti. Inoshandiswawo mukuvhiya tsoka, c-zvikamu, kuvhiyiwa kwepurasitiki, kuvhiyiwa nemuromo, nezvimwe. Vanhu vazhinji vakanaka pazviri, kunze kweavo vanopokana neanotindivadza emunharaunda uye avo vane chirwere chechiropa, maererano naDr. Smith.

Iyo chete yakadzika pasi? "Nepo anoshanda kwenguva refu anesthetics emuno senge Exparel inogona kubatsira kudzikisa kudikanwa kweopioid postoperative, aya anodhura uye varwere vazhinji vanosarudza hupfumi hweiyo opioid sarudzo," anodaro Adam Lowenstein, MD, chiremba wepurasitiki uye wemigraine. Mamwe marongero einishuwarenzi anogona kuivhara kana kuifukidza zvishoma, asi hazvisi izvo zvinoitika. Zvakadaro, inopa sarudzo inobatsira kune avo vane chokwadi chekuti havadi maopioid post-op.

New C-Chikamu Tech

"C-zvikamu kuvhiya kukuru, saka vangangoita vakadzi vese vanogamuchira opioid post cesarean," anodaro Robert Phillips Heine, MD, ob-gyn kuDuke University Medical Center. "Tichifunga kuti kusununguka kwecesarean ndiyo nzira inowanzoitwa yekuvhiya muUnited States, zvingava zvinobatsira kuderedza kuwanda kwemishonga inodhaka inodiwa, sezvo kuvhiyiwa kukuru inzira inozivikanwa yekutsamira kweopioid," anowedzera kudaro. (Yakabatana: Ari maOpioid Chaizvo Anodiwa Mushure meC-Chikamu?)

Pamusoro pesarudzo dzeanesthetic seExparel, pane zvakare chimwe chinhu chinonzi yakavharwa incision negative pressure therapy inogona kuderedza kudiwa kwemaopioid mushure mechikamu chec. "Yakavharwa incision yakaipa pressure therapy inodzivirira iyo incision kubva pakusvibiswa kwekunze, inobatsira kubata mipendero yekucheka pamwe chete, uye inobvisa mvura uye hutachiona zvinhu," Dr. Heine anodaro. "Chipfeko chisina hutachiona chinoiswa pakuchekwa uye chakanamatira pombi iyo inounza kumanikidza kwakaramba kuripo uye inogara panzvimbo kwemazuva mashanu kusvika manomwe." Izvi zvakatanga kuitwa kudzivirira hutachiona mushure mekuvhiyiwa, asi vanachiremba vakaona kuti zvakakonzeresa kudzikiswa kwehuwandu hwemishonga yekurwadziwa inodiwa nevakadzi vaive nayo. Parizvino, nzira iyi iri kunyanya kushandiswa kune varwere vane njodzi huru yekutapukirwa, sevaya vane BMI inopfuura makumi mana, sezvo vari ivo varwere tsvagiridzo inoratidza mabhenefiti, Dr. Heine anodaro. "Kana imwe data ikawanikwa iyo inoratidza kuti inodzivirira hutachiona uye / kana kudzikisira kushandiswa kwezvinodhaka muvarwere vane njodzi shoma, inogona kuzoshandiswa munharaunda iyoyo zvakare."

Kuedzwa kweDNA

Isu tinoziva kuti kupindwa muropa nechero magene, uye vaongorori vanofunga kuti vakaisa mamwe magene anogona kufanotaura kana mumwe munhu achizopindwa muropa nemaopioid kana kwete. Iye zvino, pane bvunzo yekumba yaunotora kuti utarise njodzi yako. Imwe yeanonyanya kufarirwa inonzi LifeKit Predict, iyo inogadzirwa nePrescient Medicine. Zvinoenderana nekutsvaga kwakaburitswa mu Annals yeClinical Laboratory Sayenzi, nzira nyowani dzekuyedza dzinoshandiswa nePrescient dzinogona kufanotaura ne97 muzana chokwadi kana mumwe munhu ari panjodzi yakaderera yekupindwa muropa neopioid. Kunyangwe chidzidzo ichi chaive chidiki uye vamwe vanachiremba vane chekuita nekambani iyi vaive chikamu chekudzidza, zvinoita sekunge kuratidza kuti bvunzo iyi inogona kuve yakakosha kune mumwe munhu ane hanya nenjodzi yavo yekupindwa muropa.

Izvo zvakakosha kuti uzive kuti bvunzo iyi zvirokwazvo haigone kuvimbisa kuti mumwe munhu achave kana kuti haazove akapindwa muropa nemaopioid, asi inogona kupa ruzivo rwakakosha kune avo vari kuita sarudzo yekuziva nezve kuti voshandisa here. Muedzo unovharwa nemamwe marongero einishuwarenzi, uye kunyangwe iwe usingade mushonga kuti uutore, Prescient anokurudzira zvikuru kutaurirana nachiremba wako nezve bvunzo nemhedzisiro kana uchinge wazviwana. (Yakabatana: Kune Kumba-Kurapa Kurapwa Kuedzwa Kunokubatsira Iwe Kana Kukuvadza Iwe?)

Regenerative Medicine

Kana iwe wakambonzwa nezve masero masero uchireva kudonhedza, unogona kushamisika kuona kuti arikushandiswa kuwedzera mukurapa senzira yekugadzirisa marwadzo. Stem cell therapy chikamu cheimwe tsika yakakura inonzi regenerative mushonga. "Mushonga wekudzorera inzira yekuchinja pakurapa zvirwere zvakawanda uye kukuvara," anotsanangura kudaro Kristin Comella, Ph.D., Chief Science Officer weAmerican Stem Cell Centers of Excellence. "Iri kuramba ichingokura, uye inosanganisira nzira dzakasiyana siyana, senge stem cell therapy, kuti ubatanidze nzira dzekuporesa dzemuviri wako." Nepo mishonga yeopioid inogadzirisa zviratidzo zvinorwadza, stem cell kurapwa inoitirwa kugadzirisa chiri kukonzera marwadzo. "Nenzira iyi, stem cell Therapy inogadzirisa marwadzo uye inogona kudzikisira kudiwa kwekurwadziwa kuburikidza nemaopioid," anodaro Comella.

Saka chii chaizvo chinonzi kurapa? "Masero emadzinde aripo mumucheka wese mumiviri yedu uye basa rawo chairo nderekuchengetedza nekugadzirisa nyama dzakakuvadzwa," Comella anoti. "Vanogona kuparadzaniswa kubva kune imwe nzvimbo mumuviri wako uye kutamiswa kune imwe nzvimbo inoda kurapwa, kugadzirisa marwadzo munzvimbo dzakasiyana-siyana." Zvakakosha, masero emadziro anongoshandiswa chete kubva kune yako own muviri mukurapa uku, unobvisa zvimwe zvirevo zvinouya pamwe nezwi rekuti "masero emadzinde."

Dzimwe nguva, stem cell therapy inosanganiswa neplatelet-rich plasma therapy (PRP), iyo Comella anoti inoita senge fetireza ye stem maseru. "PRP huwandu hwakafumiswa hwezvinhu zvekukura uye mapuroteni akawanikwa kubva muropa remunhu. Inosimudzira kupora kwakaburitswa neanowanzoitika anti-anogumbura masero masero," anotsanangura. "PRP inobudirira kwazvo pakurapa marwadzo anokonzerwa nekukuvara kutsva nekuti inosimudzira maseru ekurapa ayo ave kutorima sezvaari kuenda kunzvimbo yakakuvara." Uye, kurapwa kwacho kunogona zvakare kushandiswa kumhanyisa anti-anogumbura marwadzo ekurapa kune zvimwe zvisingaperi nyaya senge osteoarthritis, Comella anodaro.

Zvakakosha kucherechedza kuti stem cell therapy haisi chaizvo zvakanyanya, uye haina FDA-inogamuchirwa. Nepo iyo FDA (uye vazhinji vaongorori vezvekurapa, vechinhu ichocho) vachibvuma kuti stem cell therapy iri kuvimbisa, havatendi kuti pane tsvagiridzo yakakwana pamusoro payo kuibvumidza sekurapa. Nyaya refu ipfupi: Hazvina zvakanyanya zvekuti FDA haifungi kuti stem cell therapy inoshanda, zvakanyanya kuti isu hatina ruzivo rwakakwana rwekuishandisa zvakachengeteka kana nekuvimbika.Nekungoita kunze kwekurwara, general-anesthesia-isina maitiro anotarisirwa navanachiremba vachishandisa maseru evarwere, hazvo, makemikari emakemikari emagetsi anokwanisa kushanda mukati memirawo yeDFA.

Nepo mushonga wekuvandudza ungasakurudzirwe nachiremba wako-uye zvechokwadi haungafukidzwe neinishuwarenzi yako-ichiri kutarisa kunonakidza kumberi kwemushonga ungave wakaita makumi emakore kubva zvino.

Ongororo ye