Chii Chitsva nePPMS Kurapwa? Nhungamiro Yezvekushandisa

Zvemukati

• Kutsvaga kwezvinodhaka kubva kuNINDS
• Mishonga yekurapa
• Gene kugadzirisa
• Mazano ekuvandudza
• Kurapa kwepanyama uye kutsvagisa mukurovedza muviri
• Innovations mune yekurapa kurapwa
• Kliniki miedzo yePPMS
• Iyo ramangwana rekurapa kwePPMS

Zvitsva mu Multiple Sclerosis Kurapa

Primary progressive multiple sclerosis (PPMS) haina mushonga, asi sarudzo zhinji dziripo dzekugadzirisa mamiriro acho. Kurapa kunotarisa kudzikisira zviratidzo uchidzikisa mukana wekuremara zvachose.

Chiremba wako anofanira kunge ari wekutanga kurapa PPMS. Ivo vanogona kukupa iwe manejimendi kuraira sezvavanotarisa kufambira mberi kwechirwere.

Nekudaro, iwe uchiri kuve unofarira kutsvaga zvimwe zviwanikwa zvePPMS kurapwa. Dzidza nezve mikana pano.

Kutsvaga kwezvinodhaka kubva kuNINDS

Sangano reNational Institute of Neurological Disorders uye Stroke (NINDS) rinoitisa ongororo mumarudzi ese e multiple sclerosis (MS).

Iyo NINDS ibazi reNational Institutes of Health (NIH), uye inotsigirwa nemari yehurumende. Iyo NINDS parizvino iri kuongorora mishonga inogona kugadzirisa myelin nemajini anogona kudzivirira kutanga kwePPMS.

Mishonga yekurapa

Muna 2017, ocrelizumab (Ocrevus) yakagamuchirwa neKudya neDrug Administration (FDA) yekurapa PPMS uye kudzoreredza-kuregedzera MS (RRMS). Uyu mushonga unobaya jekiseni ndiyo yekutanga uye chete PPMS mushonga pamusika.

Sekureva kweNINDS, mimwe mishonga mukusimudzira inoratidzawo kuvimbisa. Iyi yekurapa mishonga yaizoshanda nekudzivirira myelin maseru kubva mukutsva uye kuchinja kuva maronda. Ivo vanogona kudzivirira myelin maseru kana kubatsira kuagadzirisa mushure mekurwisa kwekurwisa.

Iyo yemumuromo zvinodhaka cladribine (Mavenclad) ndeimwe yakadaro muenzaniso.

Mimwe mishonga iri kuongororwa inogona kukurudzira kusimudzira kwe oligodendrocyte. Oligodendrocyte akasarudzika maseru ehuropi ayo anobatsira mukugadzirwa kwemasero matsva e-myelin.

Gene kugadzirisa

Icho chaicho chikonzero chePPMS - uye MS yakazara - hazvizivikanwe. Chinhu chinonzi magene chinofungidzirwa kuti chinobatsira mukukura kwechirwere. Vatsvakurudzi vanoramba vachidzidza basa remajini muPPMS.

Iyo NINDS inoreva magene anogona kuwedzera njodzi yeMS se "zvinokanganisa majini." Sangano iri rinotarisa mumishonga inogona kushandura magene aya MS isati yakura.

Mazano ekuvandudza

National Multiple Sclerosis Society nderimwe sangano rinopa zvigadziriso pane zvitsva pakurapa.

Kusiyana neNINDS, Sosaiti isangano risingabatsiri. Basa ravo nderekuparadzira ruzivo nezve MS uku uchisimudza mari yekutsigira zvekurapa.

Sechikamu chebasa rayo rekutsigira kutsigira kwevarwere, Sosaiti inowanzo gadziridza zviwanikwa pawebhusaiti yayo. Nekuti sarudzo dzemushonga dzakaganhurwa, unogona kuwana zviwanikwa zveruzhinji pakumutsiridza zvinobatsira. Pano vanotsanangura:

• kurapa kwepanyama
• kurapwa kurapa
• kugadzirisa kugadzirisa
• kurapa kwehunyanzvi (kwemabasa)
• kutaura-mutauro pathology

Panyama uye zvekurapa zvekurapa ndiwo maitiro akajairika ekugadzirisa muPPMS. Kutevera ndeimwe yezvazvino zvigadzirwa zvinosanganisira aya marapirwo maviri.

Kurapa kwepanyama uye kutsvagisa mukurovedza muviri

Physical therapy (PT) inoshandiswa senzira yekuvandudza muPPMS. Zvinangwa zve PT zvinogona kusiyana zvichienderana nekuoma kwezviratidzo zvako. Inonyanya kushandiswa ku:

• batsira vanhu vane PPMS kuita mabasa ezuva nezuva
• kukurudzira kuzvimiririra
• kunatsiridza chengetedzo - semuenzaniso, kudzidzisa matekinoroji ekuenzanisa anogona kudzora njodzi yekudonha
• kuderedza mikana yekuremara
• ipa rutsigiro rwepfungwa
• ona kudikanwa kwemidziyo yekubatsira kumba
• kunatsiridza huwandu hwehupenyu

Chiremba wako angangodaro achikurudzira kurapwa kwemuviri munguva pfupi mushure mekutanga kuongororwa. Kugara uchiita zvekuita nezvekurapa uku kwakakosha - usamirira kusvikira zviratidzo zvako zvafambira mberi.

Kurovedza muviri chikamu chakakosha chePN. Inobatsira kugadzirisa kufamba kwako, simba, uye huwandu hwekufamba kuti iwe ugone kuchengetedza rusununguko.

Vatsvagiri vari kuenderera mberi nekutarisa mabhenefiti eerobic kurovedza muviri mumhando dzese dzeMS. Maererano neNational Multiple Sclerosis Society, kurovedza muviri hakuna kukurudzirwa zvakanyanya kusvika pakati pema1990. Apa ndipo apo dzidziso yekuti kurovedza muviri yanga isina kunaka kuMS yakazobviswa.

Murapi wako wepanyama anogona kukurudzira maekisesaizi aoboboti iwe aunogona kuita - zvakachengeteka - pakati pekugadzwa kuti uvandudze zviratidzo zvako uye kuvaka simba rako.

Innovations mune yekurapa kurapwa

Therapy yebasa iri kuramba ichizivikanwa seyechinhu mukurapa kwePPMS. Inogona kubatsira pakuzvichengeta-wega uye nekubasa, uye inogona kubatsira ne:

• mabasa ekuzorora
• kutandara
• kushamwaridzana
• kuzvipira
• maneja manejimendi

OT inowanzoonekwa seyakafanana ne PT. Kunyangwe aya marapirwo achibatsirana, iwo ega ane chekuita nezveakasiyana maficha ePPMS kurapwa.

PT inogona kutsigira simba rako nekufamba, uye OT inogona kubatsira nezviitiko zvinokanganisa kuzvimirira kwako, sekugeza nekupfeka wega. Zvinokurudzirwa kuti vanhu vane PPMS vatsvage zvese PT uye OT kuongororwa uye kurapwa kunotevera.

Kliniki miedzo yePPMS

Iwe unogona zvakare kuverenga nezve izvozvi uye zviri kubuda kurapwa kwePPMS kuClinicalTrials.gov. Iri rimwe bazi reNIH. Basa ravo nderekupa "dhatabhesi yezvidzidzo zvekiriniki zvakavanzika uye zvepachena zvakaitiswa pasirese."

Pinda "PPMS" mune iyo "Mamiriro kana chirwere" munda. Iwe unowana akawanda anoshanda uye akapedzwa zvidzidzo zvinosanganisira mishonga uye zvimwe zvinhu zvinogona kukanganisa chirwere.

Pamusoro pezvo, iwe unogona kufunga kutora chinhano mukuedzwa kwekiriniki iwe pachako. Uku kuzvipira kwakakomba. Kuti uve nechokwadi chekuchengetedzeka kwako, unofanirwa kutanga watanga nekukurukura nezvekiriniki miedzo.

Iyo ramangwana rekurapa kwePPMS

Iko hakuna mushonga wePPMS, uye sarudzo dzemushonga dzinogumira. Kutsvagisa kuchiri kuitwa kutsvaga zvinodhaka kunze kweo ocrelizumab iyo inogona kubatsira kudzora zvinofambira mberi zviratidzo.

Kunze kwekutarisa mukati pamwe nachiremba wako nguva dzose, shandisa zviwanikwa izvi kuti ugare uine ruzivo nezve zvitsva zvazvino mukati mekutsvaga kwePPMS. Rakawanda basa riri kuitwa kuti unzwisise zvirinani PPMS uye kubata vanhu zvakanyanya.