Chisingaperi Myeloid Leukemia Maonero uye Hupenyu Hwako Tarisiro

Zvemukati

• Zvikamu zveCML
• Kurapa nzira
• Outlook
• Pasi rose mitengo yekupona
• Kupona kwemitengo nechikamu

Kunzwisisa chisingaperi myeloid leukemia

Kudzidza kuti une kenza kunogona kukurira. Asi huwandu hunoratidza kupona kwakanaka kweavo vane chisingaperi myeloid leukemia.

Chisingaperi myeloid leukemia, kana CML, imhando yekenza inotanga mumongo wemapfupa. Inokura zvishoma nezvishoma mumasero anogadzira ropa mukati memongo uye pakupedzisira inopararira kuburikidza neropa. Vanhu vanowanzo kuve neCML kwenguva yakati rebei vasati vaona chero zviratidzo kana kutoziva kuti vane cancer.

CML inoita kunge inokonzereswa neyakajairika geni inoburitsa yakawandisa enzyme inonzi tyrosine kinase. Kunyangwe iri chibereko chakatangira, CML haina kugarwa nhaka.

Zvikamu zveCML

Pane zvikamu zvitatu zveCML:

• Chikamu chisingaperi: Pakati pechikamu chekutanga, maseru ekenza ari kukura zvishoma nezvishoma. Vanhu vazhinji vanoonekwa panguva yechikamu chisingaperi, kazhinji mushure mekuongororwa kweropa kunoitwa zvimwe zvikonzero.
• Yakawedzera chikamu: Masero eleukemia anokura uye anokurumidza kukurumidza muchikamu chechipiri.
• Blastic chikamu: Muchikamu chechitatu, masero asina kujairika akakura kunze kwekudzora uye ari kuwanda kunze kwakajairika, maseru ane hutano.

Kurapa nzira

Munguva yechikamu chisingaperi, kurapwa kazhinji kunosanganisira mishonga yemumuromo inonzi tyrosine kinase inhibitors kana TKIs. TKIs inoshandiswa kuvhara chiito cheprotein tyrosine kinase uye kumisa maseru ekenza kubva mukukura nekuwanda. Vanhu vazhinji vanorapwa neTKI vanozoenda mukuregererwa.

Kana maTKI asingabatsiri, kana kurega kushanda, ipapo munhu wacho anogona kuenda muchikamu chinokurumidza kana chakashata. A stem cell transplant kana bone marrow kuisirwa kazhinji inhanho inotevera. Izvi zvinoshandiswa ndiyo chete nzira yekurapa CML, asi panogona kuve nematambudziko akakomba. Nechikonzero ichi, kuisirwa zvinowanzoitwa chete kana mishonga isingashande.

Outlook

Kufanana nezvirwere zvakawanda, maonero evaya vane CML anosiyana zvichienderana nezvinhu zvakawanda. Zvimwe zvacho zvinosanganisira:

• chikamu chipi chavari
• zera ravo
• hutano hwavo hwese
• platelet kuverenga
• kunyangwe tsinga yakawedzerwa
• huwandu hwekukuvara kwemapfupa kubva muleukemia

Pasi rose mitengo yekupona

Kenza yekupona mitengo inowanzo kuyerwa mumakore mashanu emakore. Sekureva kweNational Cancer Institute, data rese rinoratidza kuti vangangoita 65.1 muzana yeavo vanoonekwa kuti vane CML vachiri vapenyu makore mashanu apfuura.

Asi mishonga mitsva yekurwisa CML iri kuvandudzwa uye kuyedzwa nekukurumidza, ichiwedzera mukana wekuti ramangwana rekupona ramangwana riwedzere.

Kupona kwemitengo nechikamu

Vanhu vazhinji vane CML vanoramba vari muchikamu chisingaperi. Mune zvimwe zviitiko, vanhu vasingagamuchire kurapwa kunoshanda kana vasingapindure zvakanaka pakurapwa vanozoenda kuchikamu chinokurumidza kana chakatsvuka. Maonero panguva dzezvikamu izvi zvinoenderana nekuti ndeapi marapirwo avakatoyedza uye kuti ndeapi marapiro anogona kushivirirwa nemiviri yavo.

Maonero acho ane tariro kune avo vari muchikamu chisingaperi uye vari kugamuchira maTKI.

Zvinoenderana nekudzidza kukuru kwa2006 kwechirwere chitsva chinonzi imatinib (Gleevec), paive ne83 muzana yehupenyu hwekupona mushure memakore mashanu kune avo vakagamuchira mushonga uyu. Chidzidzo che2018 chevarwere nguva dzose vachitora mushonga imatinib vakawana kuti 90 muzana vaigara makore mashanu. Imwe ongororo, yakaitwa muna2010, yakaratidza kuti mushonga unonzi nilotinib (Tasigna) wainyanya kushanda kupfuura Gleevec.

Ose maviri emishonga iyi ave marapirwo akajairwa panguva yechikamu chisingaperi cheCML. Kupona kwehuwandu hwehuwandu hwekutarisirwa kunotarisirwa kuwedzera sezvo vanhu vazhinji vachigamuchira izvi nemimwe mitsva, inoshanda zvikuru mishonga.

Muchikamu chinokurumidza, mwero wekupona unosiyana zvakanyanya zvichienderana nekurapwa. Kana munhu wacho achipindura zvakanaka kune maTKI, mitengo inenge yakaita senge kune avo vari muchikamu chisingaperi.

Pakazara, kupona kwemitengo yeavo vari muchikamu cheblastic hover pazasi pe20 muzana. Mukana wakanakisa wekupona unosanganisira kushandisa madhiragi kuti adzosere munhu muchikamu chisingaperi uyezve kuyedza tsindiro yesero.