Ndezvipi Peyer's Patches?

Zvemukati

• Tsanangudzo
• Vari kupi?
• Chii chiri basa ravo?
• Mhinduro kuhutachiona
• Oral immune kushivirira
• Mamiriro ezvinhu anosanganisira zvigaro zvaPeyer
• Hutachiona hutachiona
• Utachiona hwehutachiona
• Chirwere cheCrohn uye ulcerative colitis
• Zvirwere zvePron
• Chinokosha

Tsanangudzo

Peyer's patches akaunganidzwa eiyo lymphoid follicles mune iyo mamukisi membrane iyo inoisa ako mudumbu ura. Lymphoid follicles inhengo diki mune yako lymphatic system iyo yakafanana neyema lymph node.

Yenyu lymphatic system inoumbwa nematishu uye nhengo dzine masero machena eropa, ayo anobatsira muviri wako kurwisa hutachiona. Yako spleen, bone marora, uye lymph node ese chikamu cheyymphatic system.

Peyer's patches anoita basa rakakosha mukuchengetedza hutachiona hwezvinhu mukati megadziriro yako yekugaya. Kuongorora immune pazvinhu zvinoreva maitiro anoita kuti immune system yako ione uye nekuparadza zvinogona kuita utachiona.

Vari kupi?

Peyer's patches ari mune ako mudumbu ura, kazhinji munzvimbo yeileum. Iyo ileum ndiyo yekupedzisira chikamu chemuviri wako mudumbu. Pamusoro pekuwedzera kugaya chikafu chaunodya, iyo ileum inotorawo mvura uye zvinovaka muviri kubva muchikafu.

Vazhinji vanhu vane pakati pe30 ne40 Peyer's patches, uye vanhu vadiki vanowanzove nevanopfuura vanhu vakuru. tenda huwandu hwezvikwata zvePeyer mune yako ileum peaks muma20s ako.

Saizi, chimiro, uye kugoverwa kwese kwemakanda aPeyer anosiyana kubva pamunhu kusvika kumunhu.

Chii chiri basa ravo?

Peyer's patches ane maviri akakosha mashandiro ane chekuita neyako immune system uye kuti inopindura sei kune angangoita hutachiona.

Mhinduro kuhutachiona

Peyer's patches ane akasiyana maseru ekudzivirira, anosanganisira macrophages, dendritic masero, T maseru, uye B maseru. Kune mamwewo maseru akasarudzika, anonzi M maseru, padhuze nematavi ako ePeyer. Aya M maseru anodyisa maantigen kune macrophage uye dendritic maseru eako Peyer's patches. An antigen chinhu, senge hutachiona, icho chinogona kuburitsa mhinduro kubva ku immune system yako.

Iwo macrophage uye dendritic maseru anozoratidza aya maantigen kune ako maT masero nemaB maseru, ayo anoona kuti kana kwete antigen inoda mhinduro yemumuviri. Kana ivo vakaona antigen sehutachiona hunokuvadza, masero eT nemaB masero ari muzvikwata zvako zvaPeyer anoratidza immune system yako kuti irwisane nayo.

Dzimwe nguva, mabhakitiriya uye hutachiona hunogona kubiridzira iyi michina uye voishandisa kupinda mukati meimwe muviri wako kuburikidza neura hwako hudiki.

Oral immune kushivirira

Chese chinhu chaunodya chinozopedzisira chaenda kuura hwako hudiki. Muviri wako haugamuchire zvekudya sezvinhu zvekunze nekuda kwechinhu chinonzi muromo wekudzivirira immune. Izvi zvinoreva kudzivirirwa kwema immune immune kune mamwe maantigen. Peyches yako yaPeyer inowanzo sampling zvinhu mukati medu dumbu diki, saka vanogona kutamba chinhanho pakusarudza kuti ndezvipi zvinhu zvinoda mhinduro yemumuviri.

Hapana ane chokwadi nezve iro basa chairo rezvikwata zvaPeyer mune ino maitiro. A yakaratidza chidzidzo chakakodzera chinosanganisira mbeva. Mbeva dzakaderedzwa Peyer's chigadziriso chakava nenguva yakaoma kuregerera mapuroteni sevanhu vakuru, asi kwete mamwe makomponi. Zvisinei, kuongorora kumwe chete kwakacherechedzawo kuti zvimwe zvidzidzo zvakagumisa kuti kusava nezvigamba zvaPeyer zvinoita kunge kusingakanganise kudzvinyirira kwemuromo.

Peyer's patches angangotamba imwe mhando yebasa mukukudziridzwa kwekudzivirira immune mumuromo, asi vaongorori vachiri kuongorora izvo.

Mamiriro ezvinhu anosanganisira zvigaro zvaPeyer

Hutachiona hutachiona

Mhando dzakasiyana dzehutachiona dzinogona kupinda mumuviri wako nekunangisa M maseru uye Peyer zvigamba. Semuenzaniso, 2010 yakataura kuti Listeria monocytogenes, iyo inokonzeresa listeria, inopindirana neM M maseru uye zvigamba zvaPeyer. Iyo L. monocytogenes mabhakitiriya anogona:

• famba zvinobudirira kuburikidza neM maseru uye nekukurumidza kufamba uchienda munzvimbo dzePeyer dzemakonzo
• dzokorora mukati mematehwe aPeyer
• famba nekukurumidza kubva kumatehwe aPeyer kune dzimwe nhengo dzemukati

Dzimwe mhando dzehutachiona dzinozivikanwa kuita izvi dzinosanganisira enterohemorrhagic Escherichia coli, iyo inokonzeresa E. coli zvirwere, uye Salmonella typhimurium, izvo zvinogona kukonzera chikafu chepfu.

Utachiona hwehutachiona

Mavhairasi anogona zvakare kushandisa M maseru kuisa ako Peyer matinji uye kutanga kutevedzera. Semuenzaniso, ndakaona kuti polio, iyo inokonzera polio, inosarudza kudzokorora mukati medumbu rako diki.

Humwe hutachiona hunozivikanwa kuita izvi hunosanganisira HIV-1, iyo inokonzeresa mhando yakajairika yeHIV.

Chirwere cheCrohn uye ulcerative colitis

Chirwere cheCrohn uye ulcerative colitis marudzi maviri ehutachiona hwechirwere. Chirwere cheCrohn chinowanzo sanganisira kuzvimba kweileum yako, nepo ulcerative colitis inowanzo sanganisira yako colon.

Vanhu vane kana uye vanowanzo kuve nemaronda kana kana akakomberedza awo Peyer zvigamba, zvichiratidza kuti vanogona kuita chinzvimbo mukuvandudzwa kwemamiriro aya.

Zvirwere zvePron

Prions zvipembenene zvinogona kuchinja chimiro kana chimiro chemapuroteni, kunyanya iwo ari muuropi. Mamiriro ezvinhu anosanganisira ma prion anozivikanwa sehosha dzepion. Muenzaniso wakajairika chirwere cheCreutzfeldt-Jakob, icho chingangove chakakonzerwa neyakafanana prion inokonzeresa kupenga chirwere chemombe mumombe.

Muzviitiko zvakawanda, ma prion anonwa nechikafu, saka anowanzo pinda mudumbu rako usati wawana zvimwe zvikamu zvemuviri wako, senge huropi hwako. Vamwe vakawana huwandu hukuru hwemaprion muPeyer's zvigamba zvemhando dzinoverengeka dzemhuka. Pamusoro pezvo, mbeva dzine mashoma maPeyer anoita kunge ari kuchirwere cheprion.

Chinokosha

Peyer's patches inzvimbo diki muura hwako mudiki, kunyanya chikamu chepasi. Pamwe chete neM M maseru, ivo vanoita basa rakakosha mukuona hutachiona munzira yako yekugaya. Nekudaro, zvigamba zvaPeyer zvinogona zvakare kutora chinzvimbo mukuvandudzwa kwemamiriro akati wandei, kusanganisira chirwere chekuputira ura, kunyangwe iri basa risinganyatsonzwisisike.