Proton Pump Inhibitors

Zvemukati

• Inoshanda Sei Proton Pump Inhibitors?
• Pane Kune Akasiyana Mhando dzeProton Pump Inhibitors?
• Ndeipi Njodzi dzekushandisa Proton Pump Inhibitors?
• Matanho Anotevera

Kurapa kwe gastroesophageal Reflux chirwere (GERD) kazhinji inove nezvikamu zvitatu. Matanho maviri ekutanga anosanganisira kutora mishonga uye kugadzira kudya uye mararamiro kuchinja. Chikamu chechitatu kuvhiyiwa. Kuvhiya kunowanzo shandiswa chete senzira yekupedzisira mumatambudziko akakomba eGERD ayo anosanganisira matambudziko.

Vanhu vazhinji vanozobatsirwa nematanho ekutanga ekurapa nekugadzirisa mashandisiro, nguva, uye zvavanodya. Nekudaro, dhayeti uye marongero ehupenyu ega anogona kutadza kubatsira kune vamwe. Muzviitiko zvesesesi, vanachiremba vanogona kukurudzira kushandisa mishonga inononoka kana kumisa kugadzirwa kweacid mudumbu.

Proton pump inhibitors (PPIs) ndeimwe mhando yemishonga inogona kushandiswa kudzikisa mudumbu acid uye kubvisa zviratidzo zveGERD. Mimwe mishonga inogona kubata yakawandisa mudumbu acid inosanganisira H2 receptor blockers, senge famotidine (Pepcid AC) uye cimetidine (Tagamet). Nekudaro, maPPI anowanzo shanda kupfuura H2 receptor blockers uye anogona kudzikamisa zviratidzo muhuwandu hwevanhu vane GERD.

Inoshanda Sei Proton Pump Inhibitors?

PPIs inoshanda nekuvhara uye kudzikisa kugadzirwa kwemudumbu acid. Izvi zvinopa chero yakakanganiswa esophageal tishu nguva yekuporeswa. PPIs inobatsirawo kudzivirira kupisa kwemwoyo, kupisa kunonzwa kunowanzo kuperekedza GERD. PPIs ndeimwe yemishonga ine simba kwazvo yekubvisa zviratidzo zveGERD nekuti kunyangwe iyo shoma asidi inogona kukonzeresa zviratidzo.

PPI dzinobatsira kudzikisa mudumbu asidhi kupfuura mana kusvika gumi nemaviri-vhiki nguva. Iyi nguva yenguva inobvumira kupora kwakakodzera kweye esophageal tishu. Zvinogona kutora nguva yakareba kuti PPI igadzirise zviratidzo zvako kupfuura iyo H2 receptor blocker, iyo inowanzo kutanga kudzikisa dumbu acid mukati meawa rimwe chete. Nekudaro, kuregererwa kwechiratidzo kubva kuPPIs kunowanzo gara kwenguva yakareba. Saka mishonga yePPI inowanzo kuve yakakodzera kune avo vane GERD.

Pane Kune Akasiyana Mhando dzeProton Pump Inhibitors?

PPIs dzinowanikwa zvese pamusoro pe-iyo-piritsi uye nemushonga. Over-the-counter PPIs inosanganisira:

• lansoprazole (Prevacid 24 HR)
• omeprazole (Prilosec)
• esomeprazole (Nexium)

Lansoprazole uye omeprazole inowanikwawo nemushonga, seaya anotevera maPPI:

• dexlansoprazole (Dexilant, Kapidex)
• pantoprazole sodium (Protonix)
• rabeprazole sodium (Aciphex)

Mumwe mushonga wekunyorerwa inozivikanwa seVimovo inowanikwawo pakurapa GERD. Iine mubatanidzwa weesomeprazole uye naproxen.

Prescription-simba uye pamusoro-iyo-pikisi PPIs inoita kunge inoshanda zvakaenzana mushe mukudzivirira zviratidzo zveGERD.

Taura nachiremba wako kana zviratidzo zveGERD zvikasagadzikana neanopfuura-the-counter kana mapiritsi ePIs mukati memavhiki mashoma. Iwe unogona kunge uine Helicobacter pylori (H. pylori) hutachiona hwehutachiona. Iyi mhando yehutachiona inoda kurapwa kwakaomarara. Zvisinei, hutachiona hahuwanzokonzeri zviratidzo. Kana zviratidzo zvikaitika, zvakafanana zvikuru nezviratidzo zveGERD. Izvi zvinoita kuti zvive zvakaoma kusiyanisa pakati pemamiriro maviri aya. Zviratidzo zve H. pylori hutachiona hunogona kusanganisira:

• kusvotwa
• kugara uchibowa
• kurasikirwa nenzara
• kuzvimba

Kana chiremba wako achifungidzira kuti une H. pylori hutachiona, ivo vachamhanya bvunzo dzakasiyana kuti vasimbise kuongororwa. Ipapo vanozoona chirongwa chinoshanda chekurapa.

Ndeipi Njodzi dzekushandisa Proton Pump Inhibitors?

PPIs zvakagara zvichionekwa senge zvakachengeteka uye zvakanaka-zvinoregererwa mishonga. Nekudaro, kutsvagisa ikozvino kunoratidza kuti dzimwe njodzi dzinogona kuve nekubatanidzwa nekushandisa kwenguva refu kwemishonga iyi.

Imwe ongororo ichangoburwa yakawana kuti vanhu vanoshandisa maPPI-kwenguva refu vane zvishoma zvakasiyana mumatumbu mabhakitiriya. Uku kushomeka kwemhando dzakasiyana kunovaisa panjodzi yekuwedzera yehutachiona, kuputsika kwemapfupa, uye kushomeka kwevhitamini nemamineral. Ura hwako hune mabhiriyoni emabhakitiriya. Nepo mamwe eaya mabhakitiriya ari "akaipa," mazhinji acho haakuvadzi uye anobatsira mune zvese kubva kugaya kusvika kugadziriro yemanzwiro. PPI dzinogona kukanganisa chiyero chebhakitiriya nekufamba kwenguva, zvichikonzera mabhakitiriya "akaipa" kutora mabhakitiriya "akanaka". Izvi zvinogona kukonzera kurwara.

Pamusoro pezvo, iyo US Chikafu neDrug Administration (FDA) yakaburitsa muna 2011 iyo yakataura kushandiswa kwenguva refu kwemishonga PPI inogona kuve yakabatana neakaderera magnesium mazinga. Izvi zvinogona kukonzera matambudziko akakomba ehutano, kusanganisira mhasuru, kurova kwemoyo zvisina kujairika, uye kugwinha. Mune angangoita makumi maviri neshanu muzana ezviitiko zvakaongororwa neDFA, magnesium yekuwedzera yega haina kugadzirisa yakaderera serum magnesium mazinga. Nekuda kweizvozvo, maPPI aifanira kumiswa.

Asi iyo FDA inosimbisa kuti pane njodzi shoma yekukudziridza yakaderera magnesium mazinga kana uchishandisa pamusoro-the-counter PPIs sekurairwa. Kusiyana neyekunyorerwa PPIs, pamusoro-e-the-shanduro vhezheni zvinotengeswa pamadosi akadzika. Izvo zvakare zvakajairwa kuitirwa kwevhiki mbiri nzira yekurapwa kwete inopfuura katatu pagore.

Kunyangwe paine mikana mhedzisiro, maPPI anowanzo kuve mushonga unoshanda kwazvo weGERD. Iwe pamwe nachiremba wako munogona kukurukura nezvengozi dzingangovapo uye moona kana maPPI ariyo akanakirai.

Matanho Anotevera

Paunomira kutora maPPI, unogona kuona kuwedzera mukugadzirwa kweasidhi. Uku kuwedzera kunogona kugara kwemwedzi yakati wandei. Chiremba wako anogona kukudzora zvishoma nezvishoma kubva pamishonga iyi kuti ubatsire kudzivirira izvi kuti zviitike. Ivo vanogona zvakare kukurudzira kutora anotevera matanho ekuderedza kusagadzikana kwako kubva kune chero GERD zviratidzo:

• kudya zvidimbu zvidiki
• kupedza mashoma mafuta
• kudzivirira kuradzika pasi kweanenge maawa maviri mushure mekudya
• kudzivisa tudyo tisati tarara
• vakapfeka mbatya dzakasununguka
• kusimudza musoro wemubhedha anenge mainji matanhatu
• kudzivisa doro, fodya, uye chikafu chinokonzera zviratidzo

Ita shuwa yekubvunza chiremba wako usati warega kutora chero yakatemwa mishonga.