6 Zvikonzero zvekuyedza Biologics YeCrohn's Chirwere Chako

Zvemukati

• 1. Iwe hausi kupindura kune echinyakare Crohn's chirwere kurapwa
• 2. Une hutachiona hutsva
• 3. Unosangana nedambudziko rinozivikanwa se fistula
• 4. Unoda kuchengetedza kuregererwa
• 5. Dosing inogona kungove kamwe chete pamwedzi
• 6. Biologics inogona kuve nemhedzisiro mishoma pane steroids
• Kukunda kuzeza kwako
• Kusarudza biologic

Semunhu anorarama nechirwere cheCrohn, pamwe wakambonzwa nezve biologics uye ungangodaro wakambofunga nezvekuzvishandisa iwe pachako. Kana paine chinhu chiri kukutadzisa, wauya kurudyi nzvimbo.

Heano zvikonzero zvitanhatu zvaungade kufunga nezve iyi mhando yepamusoro yekurapa, uye matipi ekuti ungazviite sei.

1. Iwe hausi kupindura kune echinyakare Crohn's chirwere kurapwa

Pamwe wanga uchitora akasiyana Crohn's chirwere mishonga, senge steroids uye maunomomodulators, kwechinguva ikozvino. Nekudaro, iwe uchiri kuve ne flare-ups akati wandei pagore.

IAmerican College yeGastroenterology (ACG) nhungamiro inokurudzira zvikuru kutora biologic mumiririri kana iwe uine zvine mwero-kusvika-zvakanyanya chirwere cheCrohn chinopesana nesteroid kana maunomodulators. Chiremba wako anogona zvakare kufunga nezvekusanganisa biologic neiyo immunomodulator, kunyangwe kana usati waedza iwo madhiragi zvakasiyana zvakadaro.

2. Une hutachiona hutsva

Pachivanhu, zvirongwa zvekurapa chirwere cheCrohn chaisanganisira nzira yekukwira-kumusoro. Zvishoma zvinodhura zvinodhaka, senge steroid, zvakaedzwa kutanga, nepo zvakadhura biologics zvakaedzwa kwekupedzisira.

Munguva pfupi yapfuura, nhungamiro dzinotsigira nzira yekumusoro-pasi yekurapa, sehuchapupu hwakanongedzera kumigumisiro yakabudirira nemabatiro e biologic mune varwere vachangobva kuongororwa.

Semuenzaniso, kumwe kuongorora kukuru kwemashoko ekurapa ekurapa kwakawana kuti kutanga biologics kutanga munzira yekurapa chirwere cheCrohn kunovandudza mhinduro kumushonga.

Boka rekudzidza iro rakatanga anti-TNF biologics kutanga raive nemitengo yakaderera kwazvo yekuda steroid yekurapa kuputika-kupfuura mamwe mapoka ekudzidza. Vaivewo nekuvhiya kushoma nekuda kwechirwere cheCrohn.

3. Unosangana nedambudziko rinozivikanwa se fistula

Fistula hukama husina kujairika pakati pezvikamu zvemuviri. Muchirwere cheCrohn, fistula inogona kuitika kana chironda chikatambanudza kuburikidza nemukati memadziro ako, chinobatanidza ura hwako neganda, kana ura hwako uye imwe nhengo.

Kana fistula ikatapukirwa, inogona kutyisidzira hupenyu. Biologics inozivikanwa seNNF inhibitors inogona kupihwa nachiremba wako kana uine fistula nekuti inoshanda kwazvo.

Iyo FDA yakabvumidza biologics yakanangana nekurapa fistulizing chirwere cheCrohn uye kuchengetedza fistula kuvhara.

4. Unoda kuchengetedza kuregererwa

Corticosteroids inozivikanwa kuunza kuregererwa asi haigone kuchengetedza iko kuregererwa. Kana iwe wanga uchitora steroid kwemwedzi mitatu kana kupfuura, chiremba wako anogona kutanga iwe pane biologic pachinzvimbo. Zvidzidzo zvekiriniki zvinoratidza kuti anti-TNF biologics inokwanisa kuchengetedza kuregererwa kune varwere vane chirwere chakakomba chakanyanya cheCrohn.

IAACG yakaona kuti mabhenefiti emishonga iyi kuchengetedza kuregererwa anokunda kukuvadza kwevarwere vazhinji.

5. Dosing inogona kungove kamwe chete pamwedzi

Pfungwa yejekiseni inogona kutyisa, asi mushure mekutanga madhizaini, mazhinji biologics inoitiswa kamwe chete pamwedzi. Pamusoro peizvi, tsono yacho idiki kwazvo, uye mushonga unojowa pasi peganda rako chete.

Mazhinji biologics anopiwawo muchimiro che auto-injector - izvi zvinoreva kuti unogona kuwana majekiseni usina kana kuona tsono. Iwe unogona kana kuzvipa iwe pachako biologics kumba mushure mekunge iwe wakadzidziswa zvakanaka maitiro ekuzviita.

6. Biologics inogona kuve nemhedzisiro mishoma pane steroids

Corticosteroids inoshandiswa kurapa chirwere cheCrohn, senge prednisone kana budesonide, inoshanda nekudzvinyirira immune system yese.

Biologics, kune rimwe divi, shanda mune yakasarudzika nzira nekunangisa chaiwo mapuroteni mune yako immune system yatove yakaratidza kuve yakabatana neCrohn kuzvimba. Nechikonzero ichi, vane mashoma mhedzisiro pane corticosteroids.

Anenge ese mishonga anotakura njodzi yemhedzisiro. Kune biologics, iyo yakajairika mhedzisiro mhedzisiro inoenderana nemabatirwo avanopihwa. Unogona kusangana nekushatirwa kudiki, kutsvuka, kurwadziwa, kana kuita panzvimbo yekujoiwa.

Kune zvakare njodzi yakati pfuurei yehutachiona, asi njodzi yacho haina kukwirira semamwe madhiragi, akadai secorticosteroids.

Kukunda kuzeza kwako

Yekutanga biologic yechirwere cheCrohn yakatenderwa muna1998, saka biologics ine ruzivo rwakanyanya uye kuyedzwa kwekuchengetedza kuti vazviratidze. Iwe unogona kunge uchizeza kuyedza biologic kurapwa nekuti iwe wakanzwa kuti yaive "yakasimba" zvinodhaka kana iwe uri kutya iyo yakakwira mitengo.

Kunyange chiri chokwadi kuti biologics inoonekwa seyakanyanya kurapa sarudzo, biologics iri zvakare yakanangwa zvinodhaka, uye zvinoshanda chaizvo.

Kusiyana nedzimwe nzira dzekare dzekurapa chirwere cheCrohn chinoshayisa simba immune system, biologic zvinodhaka zvinonongedza chaiwo mapuroteni ekuzvimba anozivikanwa kuve anobatanidzwa muchirwere cheCrohn. Mukupesana, corticosteroid zvinodhaka zvinodzvinyirira yako ese immune system.

Kusarudza biologic

Pamberi biologics, paive nesarudzo shoma dzekurapa kunze kwekuvhiyiwa kwevanhu vane chirwere chakakomba cheCrohn. Ikozvino pane akati wandei sarudzo:

• adalimumab (Humira, Kununurwa)
• certolizumab pegol (Cimzia)
• infliximab (Remicade, Remsima, Inflectra)
• natalizumab (Tysabri)
• ustekinumab (Stelara)
• vedolizumab (Entyvio)

Iwe unofanirwa kushanda pamwe neyako inishuwarenzi kambani kuti uone kana imwe biologic yakafukidzwa pasi peurongwa hwako.

Zviri pachena kuti biologic mishonga yakavandudza mamiriro ezviitiko zvekurapa chirwere cheCrohn uye mamwe matambudziko e autoimmune. Kutsvagurudza kuri kuramba kuchikura pane biologics, zvichiita kuti zvive nyore kuti dzimwe nzira dzekurapa dzinogona kuwanikwa mune ramangwana.

Pakupedzisira, chirongwa chako chekurapa chisarudzo chakanyatsoitwa nachiremba wako.