Antiphospholipid Syndrome: Chii icho, Zvinokonzera uye Kurapa

Zvemukati

• Zviratidzo zvikuru nezviratidzo
• Chii chinokonzera chirwere
• Maitiro ekuongororwa kunoitwa
• Kurapwa kunoitwa sei
• Kurapa panguva yekuzvitakura

Antiphospholipid Antibody Syndrome, inozivikanwawo se Hughes kana kungoti SAF kana SAAF, chirwere chisingawanzoitika autoimmune chinoratidzwa nekureruka mukuumba thrombi mutsinga uye tsinga dzinokanganisa kuvhara ropa, izvo zvinogona kukonzera kutemwa nemusoro, kunetseka kufema uye kurwiswa kwemoyo, semuenzaniso.

Zvinoenderana nechikonzero, SAF inogona kuiswa muzvikamu zvitatu zvikuru.

1. Primary, umo pasina chikonzero chaicho;
2. Sekondari, inoitika semhedzisiro yechimwe chirwere, uye inowanzoenderana neSystemic Lupus Erythematosus. Sekondari APS inogona zvakare kuitika, kunyangwe iri isingawanzoitika, inosanganisirwa nezvimwe autoimmune hosha, senge scleroderma uye rheumatoid arthritis, semuenzaniso;
3. Dambudziko, inova ndiyo mhando yakaoma kwazvo yeAPS umo thrombi inogadzirwa munzvimbo dzinosvika nhatu dzakasiyana pasingasviki vhiki rimwe.

APS inogona kuitika chero zera uye mune vese vanhukadzi, zvisinei zvinowanzoitika kuvakadzi vari pakati pemakore makumi maviri nemakumi mashanu ekuberekwa. Kurapa kunofanirwa kusimbiswa nachiremba kana rheumatologist uye inotarisira kudzivirira kuumbwa kwetrombi uye kudzivirira matambudziko, kunyanya kana mukadzi ane nhumbu.

Zviratidzo zvikuru nezviratidzo

Zviratidzo zvikuru nezviratidzo zveAPS zvine chekuita neshanduko mucoagulation maitiro uye kuitika kwetrombosis, ayo makuru ari:

• Kurwadziwa pachifuva;
• Kunetseka kufema;
• Kurwadziwa nemusoro;
• Nausea;
• Kuzvimba kwemaoko ekumusoro kana ezasi;
• Kuderedza muhuwandu hwemaplatelet;
• Kubudirira kwekubvisa kwepamuviri kana shanduko muiyo placenta, pasina chikonzero chiri pachena.

Uye zvakare, vanhu vanoonekwa vaine APS vanowanzo kuve nezvinetso zveitsvo, chirwere chemwoyo kana sitiroko, semuenzaniso, nekuda kwekuumbwa kwetrombi inopesana nekutenderera kweropa, ichichinja huwandu hweropa hunosvika kunhengo. Nzwisisa chinonzi thrombosis.

Chii chinokonzera chirwere

Antiphospholipid Antibody Syndrome iite autoimmune mamiriro, zvinoreva kuti immune system pachayo inorwisa maseru mumuviri. Muchiitiko ichi, muviri unoburitsa antiphospholipid antibodies iyo inorwisa iyo phospholipids inowanikwa mumasero emafuta, izvo zvinoita kuti zvive nyore kuti ropa rigadzikane uye riite thrombi.

Chikonzero chaicho nei immune system ichiburitsa iyi mhando yeantibody haisati yazivikanwa, asi zvinozivikanwa kuti ndiyo inowanzoitika mamiriro kune vanhu vane zvimwe zvirwere zvemuviri, seLupus, semuenzaniso.

Maitiro ekuongororwa kunoitwa

Kuongororwa kweAntiphospholipid Antibody Syndrome kunotsanangurwa nekuvapo kweinenge imwechete yekiriniki uye marabhoritari maitiro, ndiko kuti, kuvapo kwechiratidzo chechirwere uye kuona kweanenge autoantibody muropa.

Pakati pemakiriniki anotariswa nachiremba pane zvikamu zveArterial kana venous thrombosis, kuitika kwekubvisa nhumbu, kuzvarwa nguva isati yakwana, zvirwere zvemuviri uye kuvapo kwenjodzi zvinhu zvetrombosis. Aya maratidziro emakiriniki anofanirwa kuratidzwa kuburikidza nekufungidzira kana kuyedzwa kwerabhoritari.

Nezve marabhoritari maitiro ndiko kuvapo kweinenge imwe mhando yeantiphospholipid antibody, senge:

• Lupus anticoagulant (AL);
• Anticardiolipin;
• Anti beta2-glycoprotein 1.

Ma antibodies aya anofanira kuongororwa nguva mbiri dzakasiyana, aine chinguva chemwedzi miviri.

Kuti kuongororwa kuve kwakanaka kune APS, zvinodikanwa kuti zvese zviyero zvinosimbiswa kuburikidza nemiedzo yakaitwa kaviri neyakaenzana yeinenge mwedzi mitatu.

Kurapwa kunoitwa sei

Kunyangwe pasina kurapwa kunokwanisa kurapa APS, zvinokwanisika kudzikisa njodzi yekuumbika kugwamba uye, nekudaro, kuoneka kwezvinetso zvakaita setrombosis kana infarction, kuburikidza nekushandisa kwakawanda kwemishonga inorwisa antagagant, yakadai seWarfarin, iri yemuromo shandisa, kana Heparin, inova yekushandisa intravenous.

Kazhinji yenguva, vanhu vane APS vari kurapwa pamwe neanticoagulants vanokwanisa kurarama hupenyu hwakajairika, zvinongokosha kuve neyakagadzwa nguva dzose nachiremba kugadzirisa madosi emishonga, pazvinenge zvichidikanwa.

Nekudaro, kuve nechokwadi chekurapa kwekurapa, zvichiri kukosha kudzivirira mamwe maitiro anogona kukanganisa mhedzisiro yeanticoagulants, sezvinoitika pakudya chikafu chine vhitamini K, senge sipinashi, kabichi kana broccoli, semuenzaniso. Tarisa uone zvimwe zvekuchengetedza zvaunofanira kutora kana uchishandisa anticoagulants.

Kurapa panguva yekuzvitakura

Mune zvimwe zviitiko zvakasarudzika, senge panguva yekuzvitakura, chiremba anogona kukurudzira kuti kurapwa kuitwe jekiseni Heparin inosanganisirwa neAspirin kana intravenous Immunoglobulin, kudzivirira kuitika kwematambudziko akadai sekubvisa, semuenzaniso.

Nokurapwa kwakakodzera, pane mikana mikuru yekuti mukadzi ane nhumbu ane APS ave nepamuviri zvakajairika, zvisinei hazvo zvakakosha kuti atariswe zvakanyanya nachiremba wekubereka, nekuti ari panjodzi huru yekuparara, kuberekwa nguva isati yakwana kana pre-eclampsia. Dzidza maitiro ekuziva zviratidzo zve preeclampsia.