Soliqua 100/33 (insulin glargine / lixisenatide)

Zvemukati

• Chii chinonzi Soliqua 100/33?
• Kubudirira
• Soliqua 100/33 generic
• Soliqua 100/33 muyero
• Mafomu emishonga uye simba
• Chipimo chemushonga Soliqua 100/33
• Ko kana ndikapotsa dosi?
• Ndichada here kushandisa mushonga uyu kwenguva refu?
• Soliqua 100/33 mhedzisiro
• Zvimwe zvakajairika mhedzisiro
• Yakakomba mhedzisiro
• Soliqua 100/33 mutengo
• Mari uye inishuwarenzi rubatsiro
• Maitiro ekutora Soliqua 100/33
• Maitiro ekupa
• Nguva
• Kutora Soliqua 100/33 nechikafu
• Dzimwe nzira kuSoliqua 100/33
• Soliqua 100/33 vs. Xultophy
• Zvishandiso
• Mafomu emishonga uye manejimendi
• Side migumisiro uye njodzi
• Kubudirira
• Mariro
• Soliqua 100/33 vs. mimwe mishonga
• Soliqua 100/33 vs. Lantus
• Soliqua 100/33 vs. Victoza
• Soliqua 100/33 vs. Toujeo
• Soliqua 100/33 vs. Adlyxin
• Soliqua 100/33 inoshandisa
• Soliqua 100/33 shandisa nemimwe mishonga
• Soliqua 100/33 uye doro
• Soliqua 100/33 kudyidzana
• Soliqua 100/33 nemimwe mishonga
• Soliqua 100/33 nemishonga uye zvinowedzera
• Mashandiro anoita Soliqua 100/33
• Iyo insulin inokanganisa sei shuga yeropa
• Zvinoitwa naSoliqua 100/33
• Zvinotora nguva yakareba sei kuti zvishande?
• Soliqua 100/33 uye nhumbu
• Soliqua 100/33 uye kuyamwisa
• Mibvunzo yakajairika nezve Soliqua 100/33
• Soliqua 100/33 inokonzera kuwedzera uremu here?
• Soliqua 100/33 insulin here?
• Soliqua 100/33 yakareba-inoshanda here?
• Inogona here Soliqua 100/33 kushandiswa kurapa mhando 1 chirwere cheshuga?
• Soliqua 100/33 yambiro
• Soliqua 100/33 kudarika
• Ovhadhozi zviratidzo
• Zvekuita kana ovhadhozi
• Soliqua 100/33 kupera uye kuchengetedza
• Ruzivo rwehunyanzvi rweSoliqua 100/33
• Zviratidzo
• Nzira yekuita
• Pharmacokinetics uye metabolism
• Contraindications
• Kuchengetedza

Chii chinonzi Soliqua 100/33?

Soliqua 100/33 izita-zita mushonga mushonga. Inoshandiswa nekudya uye kurovedza muviri kugadzirisa mashuga eropa mune vanhu vakuru vane mhando 2 chirwere cheshuga.

Soliqua 100/33 ine mishonga miviri:

• insulin glargine, inova inoshanda kwenguva refu insulin
• lixisenatide, iri yekirasi yemishonga inonzi glucagon-yakaita peptide 1 (GLP-1) receptor agonists

Soliqua 100/33 inouya sepeni yekujoinisa iyo inoshandiswa pakuzvidzivirira pasi peganda (subcutaneous). Peni yega yega ine 3 mL yemushonga mhinduro, iine zvikamu zana zve insulin glargine uye 33 mcg ye lixisenatide pa mL yesarudzo. Peni dzinoshandiswa nepeni tsono, idzo dzisina kubatanidzwa nezvipenga.

Kubudirira

Soliqua 100/33 yakawanikwa ichibudirira pakurapa mhando 2 chirwere cheshuga. Mune imwe kiriniki yekudzidza, Soliqua 100/33 yakaedzwa mune vanhu vane chirwere cheshuga cheshuga avo vakarapwa neyakareba-insulins kwemwedzi mitanhatu. Mushure memasvondo makumi matatu ekurapwa naSoliqua 100/33, vanhu ava vaive vadzora hemoglobin A1c (HbA1c) ne1.1 muzana. Ivo zvakare vaive vakadzora kutsanya mashuga eropa ne5.7 mg / dL.

Mune imwe kiriniki yekudzidza, Soliqua 100/33 yakashandiswa ne metformin kwemavhiki makumi matatu. Chidzidzo ichi chaisanganisira vanhu vakamborapwa ne metformin voga, kana ne metformin uye mumwe mushonga weshuga wemukanwa. Mushonga weSoliqua 100/33 uye metformin yakadzora HbA1c ne1.6 muzana. Izvo zvakare zvakadzora kutsanya mashuga eropa ne59.1 mg / dL.

Soliqua 100/33 generic

Soliqua 100/33 inowanikwa chete sezita rezita remishonga. Haisi ikozvino inowanikwa mune generic fomu.

Soliqua 100/33 ine maviri anoshanda madhiragi: insulin glargine uye lixisenatide. Hapana mushonga unowanikwa mune generic fomu.

Insulin glargine inogara kwenguva refu insulini inowanikwa yega semazita ezita zvinodhaka seLantus, Toujeo, uye Basaglar. Lixisenatide ndeyekirasi yemishonga inonzi glucagon-senge peptide 1 (GLP-1) receptor agonists. Inowanikwa sezita rezita rechinodhaka Adlyxin.

Soliqua 100/33 muyero

Kazhinji, chiremba wako anokutanga iwe pane yakaderera dosi yeSoliqua 100/33 uye woigadzirisa nekufamba kwenguva kuti usvike padosi yakakunakira iwe. Iyi nzira yekugadzirisa inonzi titration. Chiremba wako anozopedzisira agadza dosi diki iyo inopa zvaunoda.

Ruzivo runotevera runotsanangura madosi ayo anowanzo shandiswa kana kukurudzirwa. Zvisinei, iva nechokwadi chekutora muyero uyo chiremba wako anokuraira iwe. Chiremba wako achasarudza yakanakisa dosi kuti ienderane nezvaunoda.

Mafomu emishonga uye simba

Pakeji yega yega yeSoliqua 100/33 ine shanu dzinoraswa, dzakatemerwa Soliqua 100/33 peni dzinobaiwa pabhokisi. Peni tsono hadzina kubatanidzwa nemapeni. (Muzviitiko zvakawanda, unogona kutenga tsono dzepeni kuchitoro chemishonga. Ungangoda mushonga.)

Peni yega yega inobaiwa ine 3 mL yemushonga mhinduro, iine zvikamu mazana matatu zveinsulini glargine uye 100 mcg ye lixisenatide.

Iyo Soliqua 100/33 majekiseni ejekiseni imwe neimwe inofanirwa kushandiswa kakawanda. Iyo nhamba yenguva inogona kutangira kubva pa5 kusvika makumi maviri nguva, zvinoenderana neyako muyero. Peni yega yega inogona kushandiswa kusvika pamazuva makumi maviri nemasere mushure mekutanga kushandiswa. Mushure menguva iyoyo, iwe unofanirwa kurasa chinyoreso, kunyangwe chichiine zvimwe zvemushonga.

Peni tsono dzinofanira kungoshandiswa kamwe chete nguva imwe neimwe.

Chipimo chemushonga Soliqua 100/33

Soliqua 100/33 inowanzo gadzirirwa mumajekiseni mamwechete e15 kusvika 60 mayuniti imwe neimwe. Izwi rekuti "zvikamu" ndiyo nzira yekuyera inoshandiswa kune insulin glargine iri muSoliqua 100/33. Iyo yakanyanya dhosi pajekiseni iri makumi matanhatu mayuniti, izvo zvaizoreva 60 mayuniti e insulin glargine uye 20 mcg lixisenatide.

Kutanga kuyerwa

Iyo yakakurudzirwa kutanga dosi yeSoliqua 100/33 zvinoenderana neyako yekurapa chirwere cheshuga.

Tarira: Usati watanga Soliqua 100/33, unofanirwa kumisa mamwe marapiro ne lixisenatide kana insulin inoshanda kwenguva refu.

Kuchengeta chipimo chemushonga

Mushure mekutanga Soliqua 100/33, chiremba wako anozotarisa huwandu hweshuga yeropa rako uye anogona kugadzirisa dhizaini yako kuti usvike pamwero wakakodzera iwe. Mugadziri wemushonga uyu anokurudzira kuisa mutero kumusoro kana pasi nezvikamu zviviri kusvika zvina svondo rega rega pazvinodiwa kusangana nezvinangwa zveshuga zveropa.

Dose kugadzirisa

Iwe nachiremba wako muchashanda pamwe chete kugadzira chirongwa chekuzadzisa zvinangwa zveshuga zveropa.

Pazasi pane muenzaniso weanoshandura madosi chiremba wako anogona kukurudzira. Chiremba wako achasarudza kana iwe uchida izvi zvigadziriso. Ive neshuwa yekutora iyo dosi iyo inokurudzirwa nachiremba wako. (Usachinje dhizaini yako pasina kubvumidzwa nachiremba wako.)

Ko kana ndikapotsa dosi?

Kana iwe ukarasikirwa neiyo Soliqua 100/33, ruka iro dosi uye ramba uchienderera neyako inotevera yakarongwa dhizaini. Usaedze kubata nekutora imwe yekuwedzera dosi kana kuwedzera inotevera dosi. Izvi zvinogona kukonzera njodzi mhedzisiro.

Ndichada here kushandisa mushonga uyu kwenguva refu?

Kana Soliqua 100/33 ichishanda uye yakachengeteka kwauri, ungangoshandisa mushonga uyu kwenguva refu. Soliqua 100/33 inowanzo shandiswa kwenguva refu kurapa rudzi rwechipiri chirwere cheshuga.

Soliqua 100/33 mhedzisiro

Soliqua 100/33 inogona kukonzera zvinyoro kana zvakakomba mhedzisiro. Iyi inotevera runyorwa ine mamwe akakosha mhedzisiro mhedzisiro anogona kuitika uchitora Soliqua 100/33. Rondedzero iyi haisanganisi mhedzisiro inogona kuitika.

Kuti uwane rumwe ruzivo nezve zvingangoitika mhedzisiro yeSoliqua 100/33, kana matipi ekuti ungagadzirise sei zvinokanganisa mhedzisiro, taura nachiremba wako kana wemishonga.

Zvimwe zvakajairika mhedzisiro

Iyo yakajairika mhedzisiro mhedzisiro yeSoliqua 100/33 inogona kusanganisira:

• kusvotwa
• zvirwere zvekufema senge dzihwa kana dzihwa
• manyoka
• musoro
• hypoglycemia (yakaderera ropa shuga)

Mazhinji emhedzisiro iyi anogona kuenda mukati memazuva mashoma kana vhiki dzinoverengeka. Kana vakanyanya kuomarara kana vasingaendi, taura nachiremba wako kana wemishonga.

Yakakomba mhedzisiro

Yakakomba mhedzisiro kubva kuSoliqua 100/33 haina kujairika, asi inogona kuitika. Fonera chiremba wako ipapo kana uine zvakakomba mhedzisiro. Fonera 911 kana zviratidzo zvako zvichinzwa kutyisidzira hupenyu kana kana iwe uchifunga kuti une chirwere chekukurumidzira.

Yakanyanya mhedzisiro mhedzisiro uye zviratidzo zvavo zvinogona kusanganisira zvinotevera:

• Yakanyanya sevhiringi reaction. Zviratidzo zvinogona kusanganisira:
• mapundu
• kufashaira
• kuzvimba
• ganda rinonhuwa
• kunetseka kufema
• yakaderera BP
• Pancreatitis (kuzvimba kwepancreas). Zviratidzo zvinogona kusanganisira:
• kurwadziwa kana unyoro mudumbu rako
• kurwadziwa shure
• kusvotwa
• kurutsa
• kupindwa nechando
• kuonda
• Itsvo kukuvara. Zviratidzo zvinogona kusanganisira:
• kuderedzwa weti
• kuzvimba mumakumbo ako, makumbo, kana tsoka
• kuvhiringidzika
• kuneta
• kusvotwa
• kurwadziwa pachipfuva kana kumanikidza
• kurova kwemoyo zvisina kujairika
• pfari
• Hypokalemia (yakaderera potasium). Zviratidzo zvinogona kusanganisira:
• kushaya simba
• kuneta
• kuvimbiswa
• tsandanyama
• kurova kwemoyo zvisina kujairika

Kurera huremu kana kuonda

Mumakiriniki ekuedzwa, Soliqua 100/33 haina kuwanikwa ichikonzera kushanduka kwehuremu. Nekudaro, mune imwe kiriniki yekudzidza, vanhu vakatora Soliqua 100/33 kwemasvondo makumi matatu vakarasikirwa nezve 1.5 mapaundi.

Uye zvakare, iwo ega madhiragi ari muSoliqua 100/33 akabatanidzwa nehuremu shanduko. Soliqua 100/33 ine insulin glargine, insulin inoshanda kwenguva refu. Zvinodhaka zvine insulin zvinogona kukonzera kuwedzera uremu.

Soliqua 100/33 zvakare ine lixisenatide, glucagon-yakaita peptide 1 (GLP-1) receptor agonist. Muzvidzidzo zvakasiyana siyana zvemakiriniki, mishonga iri mukirasi yeGLP-1 yemushonga yakaratidza kuonda semhedzisiro.

Kana iwe uine hanya nezvekuchinja uremu uchishandisa Soliqua 100/33, taura nachiremba wako.

Hypoglycemia

Insulin, mumwe wemishonga iri muSoliqua 100/33, inoshandiswa kubatsira kudzikisa huwandu hweshuga yeropa. Zvisinei, shuga dzeropa dzinogona kudzikiswa zvakanyanya, izvo zvinoguma ne hypoglycemia. Hypoglycemia ndiyo yakakurisa mhedzisiro mhedzisiro inokonzerwa ne insulin zvinodhaka, kusanganisira Soliqua 100/33.

Mune zvidzidzo zvemakiriniki, hypoglycemia yakaitika muna 8.1 kusvika 17.8 muzana yevanhu vanotora Soliqua 100/33. Uye yakanyanya hypoglycemia yakaitika mune vangangoita 1 muzana yevanhu vanotora mushonga.

Zvinhu zvakawanda zvinogona kuwedzera njodzi yako ye hypoglycemia. Izvi zvinosanganisira kutora mwero yakakwira yechirwere cheshuga uye kutora zvinopfuura imwe chirwere cheshuga. Zvimwe zvinhu zvinogona kukanganisa njodzi yako zvinosanganisira kudya uye kurovedza muviri tsika, uye kana uri kutora mimwe mishonga.

Zviratidzo zve hypoglycemia zvinogona kuitika kamwe kamwe uye zvinogona kusanganisira kuzungunuka, kuneta, kukotsira, uye kuvhiringidzika. Yakakomba hypoglycemia inogona kutungamira kune akakomba mhedzisiro mhedzisiro sekugumburwa kana kutofa. Taura nachiremba wako nezvekuti kangani kaunofanirwa kutarisa mashuga eropa rako kudzivirira hypoglycemia uchitora Soliqua 100/33.

Kushungurudzika kana ganda rakakora

Iwe unotora Soliqua 100/33 nejekiseni subcutaneous, zvinoreva kuti unoipinza pasi peganda rako. Jekiseni rinotsvedza rinogona kukonzera lipodystrophy (kushushikana kana kuunyana kweganda) kutenderedza nzvimbo yejekiseni.

Kuti uderedze njodzi ye lipodystrophy, chinja nzvimbo dzaunobaya mushonga. Semuenzaniso, rimwe zuva unogona kupinza mushonga mudumbu rako, uye unotevera iwe ungashandisa chidya chako chekunze.

Kana iwe uine hanya nezveganda mhedzisiro inokonzerwa nekubairira Soliqua 100/33, taura nachiremba wako.

Itsvo kukuvara

Kukuvara kweitsvo hakuna kuonekwa muzvidzidzo zvekiriniki zveSoliqua 100/33. Nekudaro, pakave nemishumo yekukuvara kweitsvo muvanhu vanorapwa neglucagon-senge peptide 1 (GLP-1) zvinodhaka. Lixisenatide, inova imwe yemishonga iri muSoliqua 100/33, mushonga weGLP-1.

Zviratidzo zvekukuvara kweitsvo zvinogona kusanganisira:

• kuzvimba kwemakumbo, makumbo, kana tsoka
• kuneta
• kusvotwa
• kurutsa

Kukuvara kweitsvo kunowanzoitika muvanhu vaive vashaya mvura nekuda kwemimwe mhedzisiro yeSoliqua 100/33, senge kusvotwa, kurutsa, uye manyoka.

Kana iwe ukaita izvi zviratidzo uchitora Soliqua 100/33, kana uine hanya nehutano hwako hwetsvo, taura nachiremba wako.

Soliqua 100/33 mutengo

Sezvo nemishonga yese, mutengo weSoliqua 100/33 unosiyana.

Mari yako chaiyo inoenderana neinishuwarenzi yako yekuvhara.

Mari uye inishuwarenzi rubatsiro

Kana iwe uchida rutsigiro rwemari kubhadhara Soliqua 100/33, rubatsiro rwuripo. Sanofi Aventis, iyo inogadzira Soliqua 100/33, inopa Soliqua 100/33 Savings Card. Kuti uwane rumwe ruzivo, shanyira iyo webhusaiti chirongwa.

Maitiro ekutora Soliqua 100/33

Pazasi pane mamwe mirairo yekutanga yekuzvipa iwe jekiseni uchishandisa iyo Soliqua 100/33 peni. Gara uine chokwadi chekutora Soliqua 100/33 zvinoenderana nachiremba wako kana mirairo yemupi wezvehutano.

Maitiro ekupa

Nhanho 1. Gadzirira uye utarise chinyoreso chako.

Kana uku ndiko kushandiswa kwako kwekutanga, tora chinyoreso kunze kwefiriji uye tendera peni iyi isvike tembiricha yemukati.

• Unganidza doro swabs, tsono nyowani, uye yako inopinza kurasa mudziyo.
• Geza maoko.
• Bvisa peni chivharo uye uone kuti mushonga wakajeka uye hauna ruvara. (Usashandise kana mhinduro yacho isina kujeka uye isina ruvara. Mabhuru emhepo akanaka.)
• Chenesa chisimbiso cherabha nedoro swab.

Nhanho 2. Batanidza tsono nyowani.

Pamushonga wega wega, gara uchishandisa tsono nyowani. Ita shuwa kuti peni tsono inogona kushandiswa neSoliqua 100/33. Kana iwe usingazive kuti ndeapi tsono dzaunoshandisa, bvunza chiremba wako kana wemishonga.

• Bvisa peni tsono kubva payo inodzivirira.
• Kuchengeta peni tsono yakatwasuka, ichimonyorora peni.
• Bvisa peni yekunze tsono kapu uye isa parutivi. (Chengetedze kuti ushandise mushure mejekiseni.)
• Bvisa chivharo chemukati chetsono uye urasire mumarara.

Nhanho 3. Ita bvunzo yekuchengetedza.

Gara uchiita bvunzo yekuchengetedza pamberi pejekiseni rega rega kuti uve nechokwadi chekuti chinyoreso netsono zviri kushanda nemazvo.

• Rongedza iyo counter counter kuitira kuti iverenge zvikamu zviviri.
• Dhinda bhatani rejekiseni zvachose mukati uye tarisa imwe yemushonga mhinduro kuti ibude kubva kune tsono tip. Kana izvi zvikaitika, enderera kunhanho yechina.
• Kana pasina mushonga unobuda, dzokorora bvunzo yekuchengetedza kusvika katatu.
• Kana pasina mushonga unobuda mushure momuedzo mitatu, chinja tsono uye dzokorora bvunzo dzekuchengetedza.
• Kana pasina mushonga unobuda mushure mekutsiva tsono, usashandise chinyoreso nekuti chinogona kukuvara. Shandisa chinyoreso chitsva.

Nhanho 4. Sarudza yako dose.

• Dzorera iyo counter counter kusvikira iwe wasvika pane yako yakatarwa dosi.

Nhanho 5. Baya jekiseni.

Kune nzvimbo nhatu pamuviri wako dzaunogona kushandisa kune jekiseni saiti: dumbu rako (kunze kwemasentimita maviri edumbu rako), kumashure kweruoko rwako rwekumusoro (nzvimbo ine mafuta), uye chidya chako chekunze.

• Sarudza jekiseni saiti uye pukuta ganda panzvimbo yacho nedoro swab.
• Panzvimbo yejojo, isa tsono mukati meganda rako pane 90-degree angle.
• Dhinda bhatani rejekiseni pasi zvachose uye ubate kusvikira waona "0" muhwindo rewadhi.
• Mushure mekunge dhizaini yashanduka ikaita “0,” kuverenga kusvika gumi usati waburitsa bhatani rejekiseni uye kubvisa tsono. Iyi pause inobatsira kuona kuti iwe unowana iyo yakazara dosi.
• Bvisa bhatani rejekiseni uye bvisa tsono kubva paganda rako.

Nhanho 6. Rasa tsono uye chengeta chinyoreso.

• Isa peni yekunze tsono chivharo kumashure.
• Bvisa tsono kubva mudanga rinobaiwa jekiseni uye nekukurumidza rasa tsono mumudziyo unopinza. (Rasa izvo ipapo kuti usazvivhiringidze netsono nyowani.)
• Dzorera kapeni kapeni zvakare papeni.
• Chengetedza peni pakushambidza kwemukati mushure mekushandisa kwekutanga.

Nguva

Iwe unofanirwa kutora Soliqua 100/33 mukati meawa usati wadya kwekutanga kwezuva.

Kutora Soliqua 100/33 nechikafu

Soliqua 100/33 haifanire kutorwa nechikafu. Inofanira kutorwa mukati meawa usati wadya kwekutanga kwezuva.

Dzimwe nzira kuSoliqua 100/33

Mimwe mishonga iripo inokwanisa kurapa rudzi rwechipiri chirwere cheshuga. Zvimwe zvinogona kunge zvakakukodzera iwe kupfuura vamwe. Kana iwe uchifarira kutsvaga imwe nzira yeSoliqua 100/33, taura nachiremba wako kuti udzidze zvakawanda nezvemimwe mishonga inogona kukushandira zvakanaka.

Soliqua 100/33 ine mishonga miviri: insulin inoshanda kwenguva refu inonzi insulin glargine, uye glucagon-yakaita peptide 1 (GLP-1) receptor agonist inonzi lixisenatide.

Mienzaniso yemishonga inogona kushandiswa seimwe nzira kuSoliqua 100/33 inosanganisira:

• yakareba-inoshanda insulins, senge:
• insulin glargine (Lantus, Toujeo)
• Insulini detemir (Levemir)
• GLP-1 receptor agonists, senge:
• kuwedzera (Bydureon, Byetta)
• liraglutide (Victoza, Saxenda)
• lixisenatide (Adlyxin)
• semaglutide (Ozempic)
• dipeptidyl peptidase-4 (DPP-4) inhibitors, senge:
• alogliptin (Nesina)
• linagliptin (Chiedza)
• saxagliptin (Onglyza)
• sitagliptin (Januvia)
• meglitinides, akadai se:
• repaglinide (Prandin)
• nateglinide (Starlix)
• metformin (Glucophage, Glumetza, Riomet)
• sodium-glucose cotransporter 2 (SGLT2) inhibitors, senge:
• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• empagliflozin (Jardiance)
• sulfonylureas, senge:
• glimepiride (Amaryl)
• glipizide (Glucotrol)
• Glyburide (DiaBeta, Glynase)
• thiazolidinediones, akadai se:
• pioglitazone (Actos)
• rosiglitazone (Avandia)

Soliqua 100/33 vs. Xultophy

Unogona kushamisika kuti Soliqua 100/33 inofananidzwa sei nemimwe mishonga inorayirwa kushandiswa kwakafanana.Pano isu tinotarisa kuti Soliqua 100/33 uye Xultophy zvakafanana uye zvakasiyana.

Zvishandiso

Soliqua 100/33 uye Xultophy zvese zviri zviviri FDA-inogamuchirwa kuvandudza mashuga eropa muvanhu vakuru vane chirwere cheshuga chechipiri. Izvo zvese zvakatemerwa kushandiswa nekuchinja kwekudya uye kurovedza muviri.

Soliqua 100/33 uye Xultophy zvese zvine mishonga miviri, uye mishonga iyi ndeyemakirasi mamwe chete ekurapa. Izvi zvinoreva kuti vanoshanda zvakafanana nenzira mukati memuviri.

Soliqua 100/33 ine:

• insulin glargine (yakareba-inoshanda insulin)
• lixisenatide (glucagon-yakaita peptide 1 [GLP-1] receptor agonist)

Xultophy ine:

• insulin degludec (yakareba-inoshanda insulin)
• liraglutide (GLP-1 receptor agonist)

Mafomu emishonga uye manejimendi

Soliqua 100/33 uye Xultophy zvese zvinouya semhinduro yemvura mune inoraswa jekiseni rinobaya jekiseni. Ivo vaviri vanozvibaya-jekiseni pasi peganda (subcutaneous) kamwe pazuva.

Side migumisiro uye njodzi

Soliqua 100/33 uye Xultophy ine mhedzisiro yakafanana mumuviri uye nekudaro inokonzeresa mhedzisiro yakafanana.

Zvimwe zvakajairika mhedzisiro

Iyi rondedzero ine mienzaniso yemamwe akajairika mhedzisiro mhedzisiro ayo anogona kuitika neese ari maviri madhiragi (kana akatorwa zvakasiyana)

• Zvinogona kuitika nezvose Soliqua 100/33 uye Xultophy:
• zvirwere zvekufema senge dzihwa kana dzihwa
• kusvotwa
• manyoka
• musoro
• hypoglycemia (yakaderera ropa shuga)

Yakakomba mhedzisiro

Aya mazita ane mienzaniso yemhedzisiro mhedzisiro mhedzisiro inogona kuitika neSoliqua 100/33, iine Xultophy, kana nezvose zviri zviviri zvinodhaka (kana zvichitorwa zvakasiyana).

• Zvinogona kuitika naSoliqua 100/33:
• mashoma akasarudzika akakomba mhedzisiro
• Zvinogona kuitika neXultophy:
• Kenza yehutachiona *
• nduru chirwere
• Zvinogona kuitika nezvose Soliqua 100/33 uye Xultophy:
• zvakanyanya kukanganiswa nemagetsi
• yakanyanya hypoglycemia (yakanyanya yakaderera ropa shuga)
• pancreatitis (kuzvimba kwepancreas)
• kukuvara kweitsvo
• hypokalemia (yakaderera potasiamu mazinga)

Xultophy ine yambiro yebhokisi kubva kuDAA yegomarara rekenza. Nyevero yebhokisi ndiyo yambiro yakasimba iyo FDA inoda. Inozivisa vanachiremba nevarwere nezvezvinodhaka zvinogona kuva nenjodzi.

Kubudirira

Soliqua 100/33 uye Xultophy hazvina kuenzaniswa zvakananga muzvidzidzo zvekiriniki, asi zvese zviri zviviri zvakawanikwa zvichibudirira pakurapa rudzi rwechipiri chirwere cheshuga.

Muzvidzidzo zvakasiyana, Soliqua 100/33 uye Xultophy zvese zvaive zvinobudirira mukuderedza ese HbA1c uye kutsanya mashuga eropa.

• Mune kiriniki yekudzidza, Soliqua 100/33 yakaderedza hemoglobin A1c (HbA1c) ne1.1 muzana uye nekutsanya mashuga eropa ne5.7 mg / dL mushure memasvondo makumi matatu ekurapwa.
• Muzvidzidzo zvemakiriniki, Xultophy yakadzora HbA1c ne1.31 kusvika 1.94 muzana uye nekutsanya mashuga eropa ne49.9 mg / dL kusvika ku63.5 mg / dL mushure memavhiki makumi maviri nematanhatu ekurapwa. Vanhu vanoshandisa Xultophy vakawanawo anenge 4.4 mapaundi pamusoro pemavhiki makumi maviri nematanhatu ekurapwa.

Tarira: Izvo zvakakosha kuti uzive kuti kunyatsoita sei imwe yemishonga iyi inoderedza HbA1c yako kana huwandu hweshuga yeropa hunobva pane zvakawanda zvinhu, zvinosanganisira:

• shuga yako yeropa paunotanga mushonga
• kudya kwako uye maitiro ekurovedza muviri
• imwe mishonga yeshuga yaunotora
• kunyatsotevera kwako kurapa regimen

Mariro

Soliqua 100/33 uye Xultophy zvese zvinodhaka-zita zvinodhaka. Ikozvino hapana mafomu akajairika anowanikwa chero emushonga. Brand-zita mishonga kazhinji inodhura kupfuura ejeniki.

Kubva pane fungidziro kubva kuGoodRx.com, Xultophy inogona kudhura kupfuura Soliqua 100/33. Mutengo chaiwo waungabhadharira chero chinodhaka unobva pane wauri kutora, yako yeinishuwarenzi chirongwa, kwaunogara, uye pharmacy yaunoshandisa.

Soliqua 100/33 vs. mimwe mishonga

Kune mimwe mishonga kunze kweSoliqua 100/33 uye Xultophy (pamusoro) iyo inogona kushandiswa kurapa rudzi rwechipiri chirwere cheshuga. Pazasi pane enzaniso pakati peSoliqua 100/33 nemimwe mishonga yakati wandei.

Soliqua 100/33 vs. Lantus

Soliqua 100/33 ine mishonga miviri:

• insulin glargine, inova inoshanda kwenguva refu insulin
• lixisenatide, iri yekirasi yemishonga inonzi glucagon-yakaita peptide 1 (GLP-1) receptor agonists

Insulin glargine ndiwo mushonga uri muLantus. Nekuti Soliqua 100/33 naLantus vanogovana chinhu chinoshanda, vanoshanda nenzira dzakafanana mukati memuviri.

Zvishandiso

Soliqua 100/33 FDA-inogamuchirwa kuti ishandiswe nekuchinja kwekudya uye kurovedza muviri kunatsiridza huwandu hweshuga yeropa muvakuru vane chirwere cheshuga chechipiri.

Lantus FDA-inogamuchirwa kuvandudza mashuga eropa muvakuru nevana vane chirwere cheshuga 1, uye vanhu vakuru vane chirwere cheshuga chechipiri.

Mafomu emishonga uye manejimendi

Soliqua 100/33 inouya semushonga wemvura mupeni inogona kuraswa. Lantus inouya semhinduro yemvura mune yakawanda-dhiza vial kana mune inoraswa jekiseni rinokwenenzverwa. Mishonga iyi miviri inozvibaya-jekiseni pasi peganda (subcutaneous) kamwe pazuva.

Side migumisiro uye njodzi

Soliqua 100/33 uye Lantus ese ane imwechete-inoshanda insulin, insulin glargine. Naizvozvo, madhiragi ese ari maviri anogona kukonzera mhedzisiro yakafanana. Pazasi pane mienzaniso yemhedzisiro iyi.

Zvimwe zvakajairika mhedzisiro

Aya mazita ane mienzaniso yemamwe mhedzisiro mhedzisiro anogona kuitika neSoliqua 100/33, neLantus, kana neese madhiragi (kana akatorwa ega).

• Zvinogona kuitika naSoliqua 100/33:
  • kusvotwa
  • zvirwere zvekufema senge dzihwa kana dzihwa
  • musoro
  • manyoka
• Inogona kuitika naLantus:
  • kurema kuwedzera
  • lipodystrophy (induction kana kukora kweganda panzvimbo yejekiseni)
  • jekiseni saiti maitiro
• Zvinogona kuitika nezvose Soliqua 100/33 uye Lantus:
  • hypoglycemia (yakaderera ropa shuga)

Yakakomba mhedzisiro

Aya mazita ane mienzaniso yemhedzisiro mhedzisiro mhedzisiro inogona kuitika neSoliqua 100/33, neLantus, kana nezvose zviri zviviri zvinodhaka (kana zvichitorwa zvakasiyana).

• Zvinogona kuitika naSoliqua 100/33:
  • pancreatitis (kuzvimba kwepancreas)
  • kukuvara kweitsvo
• Inogona kuitika naLantus:
  • mashoma akasarudzika akakomba mhedzisiro
• Zvinogona kuitika nezvose Soliqua 100/33 uye Lantus:
  • zvakanyanya kukanganiswa nemagetsi
  • yakanyanya hypoglycemia (yakanyanya yakaderera ropa shuga)
  • mashoma potasium mazinga (hypokalemia)

Kubudirira

Kubudirira kweSoliqua 100/33 uye Lantus yakafananidzwa zvakananga muzvidzidzo zviviri. Muchidzidzo chekutanga, iyo mishonga miviri yaishandiswa yega. Muchipiri, ivo vese vaishandiswa pamwe chete ne metformin (yemuromo chirwere cheshuga chinodhaka).

Shandisa wega

Chidzidzo chekutanga chakanangana nevakuru vane mhando 2 chirwere cheshuga avo vakamborapwa neyakareba-inoshanda insulins. Yakaratidza kuti Soliqua 100/33 inogona kushanda zvirinani pane Lantus yekudzikira hemoglobin A1c (HbA1c), asi kwete zvakare mukuderedza kutsanya kweshuga yeropa.

Mushure memasvondo makumi matatu ekurapwa, Soliqua 100/33 yakadzora HbA1c ne1.1 muzana, uye nekutsanya mashuga eropa ne5.7 mg / dL. Munguva imwecheteyo nguva, Lantus yakaderedza HbA1c ne0,6 muzana, uye nekutsanya mashuga eropa ne7.0 mg / dL.

Shandisa ne metformin

Chidzidzo chechipiri chakaedza Soliqua 100/33 ine metformin yakanangana neLantus ine metformin muvanhu vakuru vane chirwere cheshuga chechipiri. Vanhu ava vakamborapwa ne metformin yega, kana ne metformin uye mumwe wemuromo chirwere cheshuga.

Kwemavhiki makumi matatu, Soliqua 100/33 ine metformin yainyanya kushanda kupfuura Lantus ine metformin. Soliqua 100/33 ine metformin yakaderedza HbA1c ne1.6 muzana uye nekutsanya mashuga eropa ne59.1 mg / dL. Lantus uye metformin, kune rimwe divi, yakadzora HbA1c ne1.3 muzana uye kutsanya mashuga eropa akaderedzwa ne55.8 mg / dL.

Ongorora: Izvo zvakakosha kuti uzive kuti kunyatsoita sei imwe yemishonga iyi inoderedza HbA1c yako kana huwandu hweshuga yeropa hunobva pane zvakawanda zvinhu, zvinosanganisira:

• shuga yako yeropa paunotanga mushonga
• kudya kwako uye maitiro ekurovedza muviri
• imwe mishonga yeshuga yaunotora
• kunyatsotevera kwako kurapa regimen

Mariro

Soliqua 100/33 uye Lantus zvese zvinodhaka-zita zvinodhaka. Ikozvino hapana mafomu akajairika anowanikwa chero emushonga. Brand-zita mishonga kazhinji inodhura kupfuura ejeniki.

Zvinoenderana nekufungidzira kubva kuGoodRx.com, Lantus kazhinji inodhura zvakaderera pane Soliqua 100/33. Mutengo chaiwo waungabhadharira chero chinodhaka unobva pane wauri kutora, yako yeinishuwarenzi chirongwa, nzvimbo yako, uye pharmacy yaunoshandisa.

Soliqua 100/33 vs. Victoza

Soliqua 100/33 ine mishonga miviri:

• insulin glargine, inova inoshanda kwenguva refu insulin
• lixisenatide, iri yekirasi yemishonga inonzi glucagon-yakaita peptide 1 (GLP-1) receptor agonists

Victoza ine chinodhaka liraglutide, inova zvakare GLP-1 receptor agonist. Nekuti Soliqua 100/33 naVictoza vanogovana chinhu chinoshanda mukirasi imwechete yemishonga, vanoshanda nenzira dzakafanana mukati memuviri.

Zvishandiso

Soliqua 100/33 iri FDA-inogamuchirwa kuvandudza mashuga eropa mune vanhu vakuru vane mhando 2 chirwere cheshuga. Izvo zvakatemwa kuti zvishandiswe pamwe nekuchinja kwekudya uye kurovedza muviri.

Victoza inobvumidzwawo kusimudzira huwandu hweshuga yeropa muvanhu vakuru vane chirwere cheshuga cheshuga pamwe nekusimudzira kudya uye kurovedza muviri. Uye zvakare, inobvumidzwa kudzikisa njodzi yematambudziko makuru emoyo sekurwadziwa kwemoyo uye kurohwa nevanhu vane chirwere cheshuga cheshuga uye chirwere chemwoyo.

Mafomu emishonga uye manejimendi

Vaviri Soliqua 100/33 uye Victoza vanouya semushonga wemvura mupeni inogona kuraswa. Mishonga iyi miviri inozvibaya-jekiseni pasi peganda (subcutaneous) kamwe pazuva.

Side migumisiro uye njodzi

Nekuti Soliqua 100/33 uye Victoza zvese zvine chinodhaka chiri cheGLP-1 kirasi yezvinodhaka, zvese zvinodhaka zvinogona kukonzera mhedzisiro yakafanana. Pazasi pane mienzaniso yemhedzisiro iyi.

Zvimwe zvakajairika mhedzisiro

Aya mazita ane mienzaniso yemamwe mhedzisiro mhedzisiro mhedzisiro inogona kuitika neSoliqua 100/33, naVictoza, kana nemishonga iyi miviri (painotorwa zvakasiyana).

• Zvinogona kuitika naSoliqua 100/33:
  • hypoglycemia (yakaderera ropa shuga)
  • zvirwere zvekufema senge dzihwa kana dzihwa
  • musoro
• Zvinogona kuitika naVictoza:
  • kuderera kwechido
  • kurutsa
  • kuvimbiswa
  • mudumbu kugumbuka
• Zvinogona kuitika nezvose Soliqua 100/33 uye Victoza:
  • kusvotwa
  • manyoka

Yakakomba mhedzisiro

Aya mazita ane mienzaniso yemhedzisiro mhedzisiro mhedzisiro inogona kuitika neSoliqua 100/33, naVictoza, kana nezvose zviri zviviri zvinodhaka (kana zvichitorwa zvakasiyana).

• Zvinogona kuitika naSoliqua 100/33:
  • hypokalemia (yakaderera potasiamu mazinga)
• Zvinogona kuitika naVictoza:
  • Kenza yehutachiona *
  • nduru chirwere
• Zvinogona kuitika nezvose Soliqua 100/33 uye Victoza:
  • zvakanyanya kukanganiswa nemagetsi
  • yakanyanya hypoglycemia (yakanyanya yakaderera ropa shuga)
  • pancreatitis (kuzvimba kwepancreas)
  • kukuvara kweitsvo

"Victoza ane yambiro yebhokisi kubva kuDFA yekenza yehutachiona. Nyevero yebhokisi ndiyo yambiro yakasimba iyo FDA inoda. Inozivisa vanachiremba nevarwere nezvezvinodhaka zvinogona kuva nenjodzi.

Kubudirira

Soliqua 100/33 uye Victoza havana kuenzaniswa zvakananga muzvidzidzo zvekiriniki, asi zvese zviri zviviri zvakawanikwa zvichibudirira pakurapa rudzi rwechipiri chirwere cheshuga.

Muzvidzidzo zvakasiyana, vese Soliqua 100/33 uye Victoza vakadzikisa HbA1c uye nekutsanya mashuga eropa mune vanhu vane chirwere cheshuga chechipiri.

• Muchidzidzo chemakiriniki, mushure memasvondo makumi matatu ekurapwa, Soliqua 100/33 yakadzora hemoglobin A1c (HbA1c) ne1.1 muzana uye nekutsanya mashuga eropa ne5.7 mg / dL.
• Mune zvimwe zvidzidzo zvemakiriniki, pamusoro pemasvondo makumi mashanu nemaviri ekurapwa, Victoza akaderedza HbA1c neinosvika 0.8 kusvika 1.1 muzana uye nekutsanya mashuga eropa ne15 kusvika 26 mg / dL.

Chidzidzo chakasiyana chemakiriniki chakaratidza kuti Victoza akaderedza njodzi yematambudziko makuru emoyo sekurwadziwa kwemoyo uye sitiroko ne13 muzana. Mhedzisiro iyi haina kudzidza mukutsvaga paSoliqua 100/33.

Tarira: Izvo zvakakosha kuti uzive kuti kunyatsoita sei imwe yemishonga iyi inoderedza HbA1c yako kana huwandu hweshuga yeropa hunobva pane zvakawanda zvinhu, zvinosanganisira:

• shuga yako yeropa paunotanga mushonga
• kudya kwako uye maitiro ekurovedza muviri
• imwe mishonga yeshuga yaunotora
• kunyatsotevera kwako kurapa regimen

Mariro

Soliqua 100/33 uye Victoza zvese zvinodhaka-zita zvinodhaka. Ikozvino hapana mafomu akajairika anowanikwa chero emushonga. Brand-zita mishonga kazhinji inodhura kupfuura ejeniki.

Zvinoenderana nekufungidzira kubva kuGoodRx.com, Victoza kazhinji inodhura kupfuura Soliqua 100/33. Iko chaiko mutengo waungabhadharira chero chinodhaka chinoenderana nedosi yako, yako inishuwarenzi chirongwa, nzvimbo yako, uye pharmacy yaunoshandisa.

Soliqua 100/33 vs. Toujeo

Soliqua 100/33 ine mishonga miviri:

• insulin glargine, inova inoshanda kwenguva refu insulin
• lixisenatide, iri yekirasi yemishonga inonzi glucagon-yakaita peptide 1 (GLP-1) receptor agonists

Insulin glargine ndiwo mushonga uri muToujeo. Nekuti Soliqua 100/33 uye Toujeo vanogovana chinhu chinoshanda, vanoshanda nenzira dzakafanana mukati memuviri.

Zvishandiso

Soliqua 100/33 iri FDA-inogamuchirwa kuvandudza mashuga eropa mune vanhu vakuru vane mhando 2 chirwere cheshuga. Inotenderwa kushandiswa nekuchinja kwekudya uye kurovedza muviri.

Toujeo FDA-inogamuchirwa kuvandudza mashuga eropa mune vanhu vakuru vane mhando 2 chirwere cheshuga, uye vakuru uye vana vane chirwere cheshuga 1.

Mafomu emishonga uye manejimendi

Soliqua 100/33 uye Toujeo ese anouya semushonga wemvura mupeni inogona kuraswa. Mishonga iyi miviri inozvibaya-jekiseni pasi peganda (subcutaneous) kamwe pazuva.

Soliqua 100/33 inouya mune imwe huwandu. Peni yega yega ine 3 mL yemushonga mhinduro, ine zvikamu 300 zve insulin glargine uye 100 mcg ye lixisenatide. Iyo yakanyanya dhosi pajekiseni iri makumi matanhatu mayuniti, izvo zvaizoreva 60 mayuniti e insulin glargine uye 20 mcg lixisenatide.

Toujeo inouya muzvikamu zviviri zvakasiyana:

• Toujeo SoloStar ine mazana mana emakiriniki e insulin glargine mu 1.5 mL yemhinduro, ine huwandu hwakakura hweyuniti makumi masere pajekiseni.
• Toujeo Max SoloStar ine mazana e900 e insulin glargine mu3 mL yemhinduro, ine yakanyanya dhizaini yezvikamu zana neshanu pajekiseni.

Side migumisiro uye njodzi

Soliqua 100/33 naToujeo vese vanogovana zvakafanana insulin-insulin, iyo yakareba kwenguva refu. Naizvozvo, madhiragi ese ari maviri anogona kukonzera mhedzisiro yakafanana. Pazasi pane mienzaniso yemhedzisiro iyi.

Zvimwe zvakajairika mhedzisiro

Aya mazita ane mienzaniso yezvakawanda zvinowanzoitika mhedzisiro inogona kuitika neSoliqua 100/33, naToujeo, kana nemishonga iyi miviri (kana ikatorwa zvakasiyana).

• Zvinogona kuitika naSoliqua 100/33:
  • kusvotwa
  • manyoka
  • musoro
• Zvinogona kuitika naToujeo:
  • kurema kuwedzera
  • jekiseni saiti maitiro
  • lipodystrophy (induction kana kushushikana munzvimbo yejekiseni)
  • kuvava
  • mapundu
  • kuzvimba mumakumbo ako, makumbo, kana tsoka
• Zvinogona kuitika nezvose Soliqua 100/33 uye Toujeo:
  • zvirwere zvekufema senge dzihwa kana dzihwa
  • hypoglycemia (yakaderera ropa shuga)

Yakakomba mhedzisiro

Aya mazita ane mienzaniso yemhedzisiro mhedzisiro mhedzisiro inogona kuitika neSoliqua 100/33, ine Toujeo, kana nezvose zviri zviviri zvinodhaka (kana zvichitorwa zvakasiyana).

• Zvinogona kuitika naSoliqua 100/33:
  • pancreatitis (kuzvimba kwepancreas)
  • kukuvara kweitsvo
• Zvinogona kuitika naToujeo:
  • mashoma akasarudzika akakomba mhedzisiro
• Zvinogona kuitika nezvose Soliqua 100/33 uye Toujeo:
  • zvakanyanya kukanganiswa nemagetsi
  • yakanyanya hypoglycemia (yakanyanya yakaderera ropa shuga)
  • hypokalemia (yakaderera potasiamu mazinga)

Kubudirira

Soliqua 100/33 uye Toujeo hazvina kuenzaniswa zvakananga muzvidzidzo zvekiriniki. Nekudaro, zvidzidzo zvega zvakaratidza kuti ese ari maviri Toujeo naSoliqua 100/33 anogona kushanda mukuderedza ese HbA1c uye kutsanya mashuga eropa.

• Mune kiriniki yekudzidza, Soliqua 100/33 yakaderedza hemoglobin A1c (HbA1c) ne1.1 muzana uye nekutsanya mashuga eropa ne5.7 mg / dL mushure memasvondo makumi matatu ekurapwa.
• Mune zvimwe zvidzidzo zvemakiriniki, Toujeo akaderedza HbA1c neinenge 0.73 kusvika 1.42 muzana uye nekutsanya mashuga eropa ne18 kusvika 61 mg / dL kwemavhiki makumi maviri nematanhatu ekurapwa.

Tarira: Izvo zvakakosha kuti uzive kuti kunyatsoita sei imwe yemishonga iyi inoderedza HbA1c yako kana huwandu hweshuga yeropa hunobva pane zvakawanda zvinhu, zvinosanganisira:

• shuga yako yeropa paunotanga mushonga
• kudya kwako uye maitiro ekurovedza muviri
• imwe mishonga yeshuga yaunotora
• kunyatsotevera kwako kurapa regimen

Mariro

Soliqua 100/33 uye Toujeo zvese zvinodhaka-zita zvinodhaka. Ikozvino hapana mafomu akajairika anowanikwa chero emushonga. Brand-zita mishonga kazhinji inodhura kupfuura ejeniki.

Zvinoenderana nekufungidzira kubva kuGoodRx.com, Toujeo kazhinji inodhura kupfuura Soliqua 100/33. Mutengo chaiwo waungabhadharira chero chinodhaka unobva pane wauri kutora, yako yeinishuwarenzi chirongwa, kwaunogara, uye pharmacy yaunoshandisa.

Soliqua 100/33 vs. Adlyxin

Soliqua 100/33 ine mishonga miviri:

• insulin glargine, inova inoshanda kwenguva refu insulin
• lixisenatide, iri yekirasi yemishonga inonzi glucagon-yakaita peptide 1 (GLP-1) receptor agonists

Lixisenatide zvakare ndiwo mushonga uri muAdlyxin. Nekuti Soliqua 100/33 uye Adlyxin vanogovana chinhu chinoshanda, vanoshanda nenzira dzakafanana mumuviri.

Zvishandiso

Soliqua 100/33 FDA-inogamuchirwa kuti ishandiswe nekuchinja kwekudya uye kurovedza muviri kunatsiridza huwandu hweshuga yeropa muvakuru vane chirwere cheshuga chechipiri.

Adlyxin ndeye FDA-inogamuchirwa kuti ishandiswe pamwe nekudya uye kurovedza muviri kusimudzira huwandu hweshuga yeropa muvakuru vane mhando 2 chirwere cheshuga.

Mafomu emishonga uye manejimendi

Soliqua 100/33 uye Adlyxin zvese zvinouya semushonga wemvura mupeni inogona kuraswa. Mishonga iyi miviri inozvibaya-jekiseni pasi peganda (subcutaneous) kamwe pazuva.

Iyo Soliqua 100/33 peni inouya mune imwe huwandu. Peni yega yega ine 3 mL yemushonga mhinduro, iine zvikamu zana zve insulin glargine uye 33 mcg ye lixisenatide pa mL. Iyo yakanyanya dhosi pajekiseni iri makumi matanhatu mayuniti, izvo zvaizoreva 60 mayuniti e insulin glargine uye 20 mcg lixisenatide.

Iyo peni yeAdlyxin inouya muzvikamu zviviri zvakasiyana:

• Iyo green Adlyxin peni ine 50 mcg / mL mu3 mL yemhinduro, ine dhizaini ye10 mcg pajekiseni.
• Iyo burgundy Adlyxin peni ine 100 mcg / mL mu3 mL yemhinduro, ine dhizaini ye20 mcg pajekiseni.

Side migumisiro uye njodzi

Soliqua 100/33 uye Adlyxin zvese zvine chinodhaka lixisenatide. Naizvozvo, ese ari maviri mishonga anogona kukonzera akafanana akafanana mhedzisiro. Pazasi pane mienzaniso yemhedzisiro iyi.

Zvimwe zvakajairika mhedzisiro

Aya mazita ane mienzaniso yemamwe mhedzisiro mhedzisiro anogona kuitika neSoliqua 100/33, neAdlyxin, kana nezvose zviri zviviri zvinodhaka (kana zvichitorwa zvakasiyana).

• Zvinogona kuitika naSoliqua 100/33:
  • zvirwere zvekufema senge dzihwa kana dzihwa
• Zvinogona kuitika neAdlyxin:
  • kurutsa
  • dzungu
• Zvinogona kuitika nezvose Soliqua 100/33 uye Adlyxin:
  • kusvotwa
  • manyoka
  • musoro
  • hypoglycemia (yakaderera ropa shuga)

Yakakomba mhedzisiro

Aya mazita ane mienzaniso yemhedzisiro mhedzisiro mhedzisiro inogona kuitika neSoliqua 100/33, neAdlyxin, kana nezvose zvinodhaka (kana zvichitorwa zvakasiyana).

• Zvinogona kuitika naSoliqua 100/33:
  • hypokalemia (yakaderera potasiamu mazinga)
• Zvinogona kuitika neAdlyxin:
  • mashoma akasarudzika akakomba mhedzisiro
• Zvinogona kuitika nezvose Soliqua 100/33 uye Adlyxin:
  • zvakanyanya kukanganiswa nemagetsi
  • yakanyanya hypoglycemia (yakanyanya yakaderera ropa shuga)
  • pancreatitis (kuzvimba kwepancreas)
  • kukuvara kweitsvo

Kubudirira

Iko kushandiswa kweiyo Soliqua 100/33 kana Adlyxin semushonga mumwe-wemushonga werudzi rwechipiri chirwere cheshuga hauna kuenzaniswa zvakananga mukutsvaga kwekurapwa.Nekudaro, kushandiswa kwemushonga wega wega pamwe chete ne metformin (yemuromo chirwere cheshuga chinodhaka) yakafananidzwa zvakananga.

Kusiyanisa zvidzidzo kana uchishandiswa wega

Muzvidzidzo zvakasiyana zvekiriniki, Soliqua 100/33 uye Adlyxin vese vaishanda vega mukuderedza kutsanya kweropa mune avo vane chirwere cheshuga chechipiri.

• Mune kiriniki yekudzidza, Soliqua 100/33 yakaderedza hemoglobin A1c (HbA1c) ne1.1 muzana uye nekutsanya mashuga eropa ne5.7 mg / dL mushure memasvondo makumi matatu ekurapwa.
• Mune imwe kiriniki yekudzidza, Adlyxin yakaderedza HbA1c ne0.57 kusvika ku0.71 muzana uye nekutsanya mashuga eropa ne4,48 kusvika 24.56 mg / dL kwemavhiki makumi maviri nemana ekurapwa.

Kuenzanisa kwakananga kana kuchishandiswa metformin

Chimwe chidzidzo chakaedza kushandiswa kweSoliqua 100/33 ine metformin yakanangana nekushandiswa kweAdlyxin ine metformin mune vanhu vakuru vane chirwere cheshuga chechipiri. Vanhu vari muchidzidzo vakamborapwa ne metformin yega, kana ne metformin uye mumwe wemuromo chirwere cheshuga.

Mushure memasvondo makumi matatu, Soliqua 100/33 ine metformin yainyanya kushanda kupfuura Adlyxin ine metformin. Soliqua 100/33 ine metformin yakaderedza HbA1c ne1.6 muzana uye nekutsanya mashuga eropa ne59.1 mg / dL. Adlyxin uye metformin, kune rimwe divi, yakadzora HbA1c ne0,9 muzana uye nekutsanya mashuga eropa ne 27.2 mg / dL.

Ongorora: Izvo zvakakosha kuti uzive kuti kunyatsoita sei imwe yemishonga iyi inoderedza HbA1c yako kana huwandu hweshuga yeropa hunobva pane zvakawanda zvinhu, zvinosanganisira:

• shuga yako yeropa paunotanga mushonga
• kudya kwako uye maitiro ekurovedza muviri
• imwe mishonga yeshuga yaunotora
• kunyatsotevera kwako kurapa regimen

Mariro

Soliqua 100/33 uye Adlyxin zvese zviri zviviri zita-zita zvinodhaka. Ikozvino hapana mafomu akajairika anowanikwa chero emushonga. Brand-zita mishonga kazhinji inodhura kupfuura ejeniki.

Zvinoenderana nekufungidzira kubva kuGoodRx.com, Adlyxin kazhinji inodhura kupfuura Soliqua 100/33. Mutengo chaiwo waungabhadharira chero chinodhaka unozotarisana nedosi rako, chirongwa cheinishuwarenzi, kwaunogara, uye famasi yaunoshandisa.

Muna Chivabvu 2020, iyo Chikafu neDrug Administration (FDA) yakakurudzira kuti vamwe vanogadzira metformin yakawedzerwa kusunungurwa vabvise mamwe emahwendefa avo kubva kumusika weU.S. Izvi zvinodaro nekuti mwero usingagamuchirike wecarcinogen inokonzeresa (kenza-inokonzeresa mumiriri) yakawanikwa mune mamwe akawedzeredzwa-kuburitsa metformin mapiritsi. Kana iwe parizvino uchitora mushonga uyu, fonera wako mupi wezvehutano. Ivo vanozopa zano kana iwe uchifanira kuenderera kutora mishonga yako kana kana iwe uchida mushonga mutsva.

Soliqua 100/33 inoshandisa

Chikafu neDrug Administration (FDA) inobvumidza mishonga yemishonga yakadai saSoliqua 100/33 kurapa mamwe mamiriro. Soliqua 100/33 FDA-inogamuchirwa kuti ishandiswe nekuchinja kwekudya uye kurovedza muviri kunatsiridza huwandu hweshuga yeropa muvakuru vane chirwere cheshuga chechipiri.

Mune 30-vhiki kiriniki yekudzidza nezve vanhu vakamborapwa nerudzi rwe basal insulin (senge insulin glargine), Soliqua 100/33 yakawanikwa ichishanda. Yakaderedza hemoglobin A1c (HbA1c) ne1.1 muzana uye nekutsanya mashuga eropa ne5.7 mg / dL.

Chidzidzo chekiriniki chemasvondo makumi matatu chakanangana nevanhu vakamborapwa ne metformin voga, kana ne metformin uye mumwe wemuromo chirwere cheshuga. Kune vanhu vari muchidzidzo, Soliqua 100/33 uye metformin yakadzora HbA1c yavo ne1.6 muzana uye nekutsanya mashuga eropa ne59.1 mg / dL.

Soliqua 100/33 shandisa nemimwe mishonga

Soliqua 100/33 inogona kushandiswa yoga kana musanganiswa nemamwe madhiragi ekuvandudza huwandu hweshuga yeropa mune vanhu vane chirwere cheshuga chechipiri. Mukurapa chirwere cheshuga, zvakajairika kuti mishonga inopfuura imwechete ishandiswe kudzora huwandu hweshuga yeropa kana mumwe mushonga wega usati wawedzera huwandu hweshuga yeropa zvakakwana.

Mienzaniso yemishonga inogona kushandiswa neSoliqua 100/33 inosanganisira:

• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• glimepiride (Amaryl)
• glipizide (Glucotrol)
• Glyburide (DiaBeta, Glynase)
• metformin (Glucophage, Glumetza, Riomet)
• pioglitazone (Actos)

Soliqua 100/33 uye doro

Dzivisa kunwa doro rakawandisa uchitora Soliqua 100/33. Doro rinogona kushandura huwandu hweshuga yeropa rako uye nekuwedzera njodzi yako ye hypoglycemia (yakaderera ropa shuga) uye pancreatitis (inflamed pancreas).

Kana iwe ukanwa doro, taura nachiremba wako nezvekuti yakawanda sei doro yakachengeteka kwauri.

Soliqua 100/33 kudyidzana

Soliqua 100/33 inogona kudyidzana nemimwe mishonga yakati wandei. Inogona zvakare kudyidzana nezvimwe zvinowedzera pamwe nezvimwe zvekudya.

Kukurukurirana kwakasiyana kunogona kukonzera mhedzisiro. Semuenzaniso, vamwe vanogona kukanganisa mashandiro anoita mushonga, asi mamwe anogona kukonzera kuwedzera mhedzisiro.

Soliqua 100/33 nemimwe mishonga

Pazasi pane runyorwa rwemishonga inogona kusangana naSoliqua 100/33. Urongwa urwu hauna mishonga yose inogona kuwirirana naSoliqua 100/33.

Usati watora Soliqua 100/33, ita shuwa yekuudza chiremba wako uye wemishonga nezvese zvinyorwe, pamusoro-pekutengesa, uye mimwe mishonga yaunotora. Vaudzewo nezve chero mavitamini, mahebhu, uye zvinowedzera zvaunoshandisa. Kugovera ruzivo urwu kunogona kubatsira iwe kudzivirira kusangana kunogona kuitika.

Kana iwe uine mibvunzo nezve kudyidzana kwezvinodhaka zvinogona kukukanganisa, bvunza chiremba wako kana wemishonga.

Mimwe mishonga yeshuga

Kutora Soliqua 100/33 nemimwe mishonga yeshuga inogona kutungamira kune yakanyanya yakadzika shuga mashuga eropa uye kuwedzera njodzi yako yehypoglycemia (yakaderera ropa shuga). Kana iwe ukatora chero ipi yemishonga iyi, ungangoda kutarisa yako mashuga eropa kakawanda. Zvakare, chiremba wako angangoda kuchinja dosi yako yeSoliqua 100/33.

Mienzaniso yeshuga mishonga inosanganisira:

• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• empagliflozin (Jardiance)
• Glyburide (DiaBeta, Glynase, Micronase)
• glimepiride (Amaryl)
• glipizide (Glucotrol)
• Kudya-nguva insulins (Humalog, Novolog)
• metformin (Glucophage)
• nateglinide (Starlix)
• repaglinide (Prandin)

Uye zvakare, kushandisa Soliqua 100/33 ine chirwere cheshuga zvinodhaka zvinonzi thiazolidinediones (TZDs) zvinogona kukonzera kuchengetedza kwemvura. Inogona zvakare kuwedzera njodzi yako yekutadza kwemoyo kana kuwedzera zviratidzo zvekutadza kwemoyo (ona yambiro pazasi). Mienzaniso yemishonga iyi inosanganisira:

• pioglitazone (Actos)
• rosiglitazone (Avandia)

Kana iwe uri kutora TZD, taura nachiremba wako usati watanga Soliqua 100/33. Kana chiremba wako achibvumira kushandisa kwako TZD paunenge uchishandisa Soliqua 100/33, ita shuwa yekutarisa zviratidzo zvekushaya kwemoyo. Kana iwe ukave nekukundikana kwemoyo, chiremba wako anogona kudzora muyero weTZD yako kana kuti iwe warega kuitora.

Zviratidzo zvekutadza kwemoyo zvinogona kusanganisira:

• kunetseka kufema
• kuzvimba makumbo, makumbo, uye tsoka
• nekukurumidza kana zvisina kujairika kurova kwemoyo
• kurwadziwa pachipfuva

Kuwedzera kweropa mishonga

Kutora Soliqua 100/33 uine imwe yepamusoro yeropa mishonga inogona kutungamira kune yakanyanya yakadzika shuga mashuga eropa uye inowedzera njodzi yako ye hypoglycemia (yakaderera ropa shuga). Kana iwe ukatora chero ipi yemishonga iyi, ungangoda kutarisa yako mashuga eropa kakawanda. Zvakare, chiremba wako angangoda kuchinja dosi yako yeSoliqua 100/33.

Mienzaniso yemakuru eropa mishonga inogona kuwedzera njodzi ye hypoglycemia painotorwa naSoliqua 100/33 inosanganisira:

• angiotensin-inoshandura enzyme (ACE) inhibitors, senge:
• benazepril (Lotensin)
• captopril
• enalapril (Vasotec)
• lisinopril (Zestril)
• angiotensin II receptor blockers (ARBs), akadai se:
• valsartan (Diovan)
• candesartan (Atacand)
• irbesartan (Avapro)
• losartan (Cozaar)
• olmesartan (Benicar)

Mimwe mishonga yeropa inogona kuvhara zviratidzo zvehutachiona hwakanyanya hweropa. Iyi mishonga inogona zvakare kuwedzera kana kudzikira kuti inoshanda sei Soliqua 100/33 iri pakudzikisa mashuga eropa. Kana iwe ukatora mishonga iyi neSoliqua 100/33, ungangoda kutarisa huwandu hweshuga yeropa kazhinji. Zvakare, chiremba wako angangoda kuchinja dosi yako yeSoliqua 100/33.

Mienzaniso yemishonga yeropa inogona kuvhara zviratidzo zvekuderera kweropa kana kukanganisa mashandiro anoita Soliqua 100/33 anosanganisira:

• clonidine (Catapres)
• metoprolol (Lopressor, Toprol-XL)
• atenolol (Tenormin)

Mimwe mishonga inogona kuvanza zviratidzo zve hypoglycemia

Mimwe mishonga inogona kuvhara zviratidzo nezviratidzo zveshuga yakadzika yeropa. Kana iwe ukatora iyi mishonga, ungangoda kutarisa yako mashuga eropa kakawanda. Zvakare, chiremba wako angangoda kuchinja dosi yako yeSoliqua 100/33.

Mienzaniso yemishonga iyi inosanganisira:

• albuterol (ProAir, Proventil, Ventolin)
• guanethidine
• reserpine

Mimwe mishonga inogona kudzikisa mashuga eropa

Kutora Soliqua 100/33 nemimwe mishonga kunogona kutungamira kune yakanyanya yakadzika shuga mashuga eropa uye kuwedzera njodzi yako yehypoglycemia (yakaderera ropa shuga). Kana iwe ukatora chero ipi yemishonga iyi, ungangoda kutarisa yako mashuga eropa kakawanda. Zvakare, chiremba wako angangoda kuchinja dosi yako yeSoliqua 100/33.

Mienzaniso yemishonga iyi inosanganisira:

• disopyramide (Norpace)
• imwe cholesterol mishonga, yakadai se fenofibrate (Tricor, Triglide) uye gemfibrozil (Lopid)
• mamwe mishonga yekudzvinyirira, senge fluoxetine (Prozac, Sarafem) uye selegiline (Emsam, Zelapar)
• octreotide (Sandostatin)
• sulfamethoxazole-trimethoprim (Bactrim, Septra)

Mimwe mishonga inowedzera shuga yako yeropa

Mimwe mishonga inogona kuwedzera huwandu hweshuga yeropa mumuviri wako. Kana iwe ukatora mishonga iyi, ungangoda kutarisa yako mashuga eropa kakawanda kudzivirira hyperglycemia (shuga yeropa). Zvakare, chiremba wako angangoda kuchinja dosi yako yeSoliqua 100/33.

Mienzaniso yemishonga iyi inosanganisira:

• albuterol (ProAir, Proventil, Ventolin)
• mamwe maantivirals, akadai seatazanavir (Reyataz) uye lopinavir / ritonavir (Kaletra)
• mamwe maSteroid, senge budesonide (Entocort EC, Pulmicort, Uceris), prednisone, uye fluticasone (Flonase, Flovent)
• mamwe ma diuretics, akadai seklorothiazide (Diuril) uye hydrochlorothiazide (Microzide)
• mamwe antipsychotic, senge clozapine (Clozaril, Fazaclo) uye olanzapine (Zyprexa)
• mamwe mahormone, senge danazol (Danazol), levothyroxine (Levoxyl, Synthroid) uye somatropin (Genotropin)
• glucagon (GlucaGen)
• niacin (Niaspan, Slo-Niacin, vamwe)
• mishonga yekudzivirira pamuromo (mapiritsi ekuberekwa)

Zvinodhaka zvinowedzera kana kudzikisa mhedzisiro yeSoliqua 100/33

Mimwe mishonga inogona kukanganisa mashandiro anoita Soliqua 100/33 mumuviri wako. Kana iwe ukatora iyi mishonga, ungangoda kutarisa yako mashuga eropa kakawanda. Zvakare, chiremba wako angangoda kuchinja dosi yako yeSoliqua 100/33.

Mienzaniso yemishonga iyi inosanganisira:

• albuterol (ProAir, Proventil, Ventolin)
• lithium

Soliqua 100/33 nemishonga uye zvinowedzera

Kutora Soliqua 100/33 nemamwe mahebhu kana zvinowedzeredza zvinogona kuwedzera njodzi yako ye hypoglycemia (yakaderera mashuga eropa). Mienzaniso yeiyi inosanganisira:

• Arifa-lipoic asidhi
• banaba
• unovava unovava
• chromium
• jimunema
• prickly peya cactus
• chena mulberry

Mashandiro anoita Soliqua 100/33

Soliqua 100/33 inobatsira kuvandudza mashuga eropa mune vanhu vane chirwere cheshuga chechipiri.

Iyo insulin inokanganisa sei shuga yeropa

Kazhinji, kana iwe uchidya chikafu, muviri wako unoburitsa mahormone anonzi insulin. Glucose (shuga) kubva muchikafu inofamba ichienda muropa rako, uye iyo insulin inobatsira kuendesa mukati memasero emuviri wako. Iwo maseru anobva achinja iyo glucose kuita simba.

Vanhu vane chirwere cheshuga cheshuga kazhinji vane insulin yekudzivirira. Izvi zvinoreva kuti muviri wavo haupindure kune insulin nenzira yazvinofanira kuita. Nekufamba kwenguva, vanhu vane mhando 2 chirwere cheshuga vanogona zvakare kurega kuburitsa yakakwana insulin.

Kana muviri wako ukasapindura insulin nenzira yainofanira kuita, kana ikasaburitsa insulin yakakwana, izvi zvinokonzeresa matambudziko. Masero emuviri wako anogona kutadza kuwana glucose yavanoda kuti ishande nemazvo.

Zvakare, iwe unogona kuwana yakawandisa glucose muropa rako. Izvi zvinonzi hyperglycemia (shuga yeropa). Kuva neglucose yakawandisa muropa rako kunogona kukuvadza muviri wako uye nhengo, kusanganisira maziso ako, moyo, tsinga, uye itsvo.

Zvinoitwa naSoliqua 100/33

Soliqua 100/33 ine mishonga miviri. Idzi idzi insulin glargine, inova yakareba-inoshanda insulin, uye lixisenatide, inova glucagon-yakaita peptide 1 (GLP-1) receptor agonist.

Insulin glargine inoshanda neimwe nzira: inoderedza shuga yako yeropa nekufambisa glucose kubva muropa rako kupinda mumaseru ako.

Lixisenatide inoshanda munzira nhatu. Kutanga, inowedzera huwandu hwe insulin muviri wako. Iyi yakawedzera insulin inobatsira kufambisa yakawanda glucose kubuda muropa rako uye kupinda mumaseru ako. Chechipiri, zvinoita kuti dumbu rako riburitse zvishoma zvishoma mushure mekudya, zvichiita kuti unzwe kuzara kwenguva yakareba. Uye chechitatu, inotaurira chiropa chako kusunungura glucose shoma muropa rako.

Zvinotora nguva yakareba sei kuti zvishande?

Soliqua 100/33 inotanga kushanda kana uchinge waijowa. Nekudaro, inosvika pakukwirira kwazvo pamusoro pe2,5 kusvika maawa matatu mushure mejekiseni rega rega.

Soliqua 100/33 uye nhumbu

Dhata yekudzidza inogumira pakushandisa Soliqua 100/33 panguva yepamuviri muvanhu. Nekudaro, zvidzidzo zvemhuka zvinoratidza kuti panogona kuve nenjodzi yekuremara kwekuzvarwa nekushandisa lixisenatide panguva yekuzvitakura. Lixisenatide mumwe wemishonga inowanikwa muSoliqua 100/33. Naizvozvo, Soliqua 100/33 inofanira kungoshandiswa chete panguva yepamuviri kana mukana wekubatsira uchipfuura njodzi dzinogona kuitika.

Kana iwe uine pamuviri kana kuronga kuve nepamuviri, taura nachiremba wako nezve njodzi uye zvakanakira kushandisa Soliqua 100/33 panguva yekuzvitakura.

Soliqua 100/33 uye kuyamwisa

Hazvizivikanwe kana Soliqua 100/33 inopfuura mumukaka wemukaka. Usati wamuyamwisa, unofanirwa kutaurirana nachiremba wako njodzi uye mabhenefiti ekutora mushonga uyu uchiyamwisa.

Mibvunzo yakajairika nezve Soliqua 100/33

Heano mhinduro kumimwe inowanzo bvunzwa mibvunzo nezve Soliqua 100/33.

Soliqua 100/33 inokonzera kuwedzera uremu here?

Mumakiriniki ekuedzwa, Soliqua 100/33 haina kuwanikwa ichikonzera kuwedzera huremu. Muchokwadi, mune imwe kiriniki yekudzidza, vanhu vakatora Soliqua 100/33 kwemasvondo makumi matatu vakarasikirwa nezve 1.5 mapaundi.

Zvinonakidza kucherechedza kuti mishonga yega yega iri muSoliqua 100/33 inoita kunge ine mhedzisiro pakurema. Mumwe wemishonga ndeye insulin glargine, inova insulin inoshanda kwenguva refu. Kazhinji, zvinodhaka zvine insulin zvakabatana nehuremu.

Nekudaro, iwo mumwe mushonga muSoliqua 100/33 unonzi lixisenatide, inova glucagon-yakaita peptide 1 (GLP-1) receptor agonist. Mishonga mune yeGLP-1 kirasi yemushonga yakaratidza kurasikirwa kwekurema semhedzisiro mhedzisiro muzvidzidzo zvakasiyana zvekiriniki.

Kana iwe uine hanya nezve mhedzisiro iyo Soliqua 100/33 inogona kuve nayo pahuremu hwako, taura nachiremba wako.

Soliqua 100/33 insulin here?

Hongu, Soliqua 100/33 ine insulin. Soliqua 100/33 inogadzirwa nemishonga miviri, imwe yacho iri insulin glargine, insulin inoshanda kwenguva refu.

Mushonga wechipiri lixisenatide, inova glucagon-yakaita peptide 1 (GLP-1) receptor agonist.

Soliqua 100/33 yakareba-inoshanda here?

Ehe. Soliqua 100/33 ine maviri anoshanda madhiragi. Imwe yeiyi insulin glargine, inova yakareba-inoshanda insulin.

Inogona here Soliqua 100/33 kushandiswa kurapa mhando 1 chirwere cheshuga?

Kwete, Soliqua 100/33 haifanire kushandiswa kurapa mhando 1 chirwere cheshuga. Soliqua 100/33 haina kudzidza kana kubvumidzwa neKudya neDrug Administration kuti irape mamiriro akadaro. Zvinotenderwa chete kurapa chirwere cheshuga cheshuga.

Soliqua 100/33 yambiro

Usati watora Soliqua 100/33, taura nachiremba wako nezve nhoroondo yako yehutano. Soliqua 100/33 inogona kunge isingave yakakunakira iwe kana uine mamwe marapirwo. Izvi zvinosanganisira:

• Itsvo chirwere. Kana iwe uine chirwere cheitsvo, kutora Soliqua 100/33 kunogona kukuvadza mamiriro ako. Kana mamiriro ako akawedzera, ungangoda kumira kutora Soliqua 100/33. Usatore mushonga uyu kana uine chirwere cheitsvo chakakomba.
• Kunonoka mudumbu kupera. Lixisenatide, mumwe wemishonga iri muSoliqua 100/33, inononoka kuita kwetsandanyama dzako dzemudumbu. Kana iwe uine gastroparesis, zvinoreva kuti muviri wako unogaya chikafu zvishoma nezvishoma, kutora Soliqua 100/33 kunogona kukuvadza mamiriro ako. Vanhu vane gastroparesis yakaoma havafanirwe kutora mushonga uyu.
• Pancreas kana nduru matambudziko, kana doro rekushandisa kusagadzikana. Soliqua 100/33 inogona kuwedzera njodzi yako yepancreatitis. Iwe unogona kunge uri panjodzi huru yepancreatitis kana iwe uine nhoroondo yepancreatitis, matombo enduru, kana kudhakwa. Kana iwe uine nhoroondo yematambudziko aya, taura nachiremba wako nezvekuti Soliqua 100/33 yakakunakira here.

Soliqua 100/33 kudarika

Kutora zvakawandisa zvemushonga uyu kunogona kuwedzera njodzi yako yemhedzisiro.

Ovhadhozi zviratidzo

Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

• yakanyanya hypoglycemia (yakanyanya yakaderera shuga yeropa), iyo inogona kukonzeresa kushushikana, kushushikana, uye kuvhiringidzika
• hypokalemia (yakaderera potasiamu mazinga), ayo anogona kukonzera kushaya simba, kupatira, uye mhasuru
• matambudziko emudumbu, ayo anogona kukonzera manyoka, kusvotwa, uye kurutsa

Zvekuita kana ovhadhozi

Kana iwe uchifunga kuti watora zvakawandisa zvemushonga uyu, fonera chiremba wako kana kutsvaga nhungamiro kubva kuAmerican Association of Poison Control Centers pa800-222-1222 kana kuburikidza nechavo online chishandiso Asi kana zviratidzo zvako zvakakomba, fonera 911 kana kuenda kukamuri yepedyo yevanokurumidza ipapo.

Soliqua 100/33 kupera uye kuchengetedza

Kana Soliqua 100/33 ikapihwa kubva kupharmasi, wemishonga achawedzera zuva rekupera kune zvakanyorwa pamudziyo. Zuva iri rinowanzo kuve gore rimwe kubva musi wakapihwa mushonga.

Chinangwa chemazuva ekupera akadaro ndechekuvimbisa kushanda kwemushonga panguva ino. Chimiro chazvino cheKudya neDrug Administration (FDA) ndechekudzivirira kushandisa akapera mishonga.

Inguva yakareba sei mushonga unoramba wakanaka unogona kubva pane zvakawanda zvinhu, zvinosanganisira kuti uye kupi mushonga unochengeterwa. Chengetedza yako Soliqua 100/33 peni mufiriji yako, pane tembiricha iri pakati pe36 ° F uye 46 ° F (2 ° C uye 8 ° C). Usambofa wakaisa chando matanga ako.

Mushure mekutanga kushandiswa kwepeni imwe neimwe, unogona kuzvichengeta patembiricha (77 ° F / 25 ° C), asi ita chokwadi chekudzivirira kubva pachiedza. Rasa peni yega yega mushure memazuva makumi maviri nemasere kubva pakushandisa kwayo kwekutanga.

Kana iwe usina kushandisa mishonga yakapfuura nguva yekupera, taura nachiremba wako nezvekuti ungangokwanisa kuishandisa.

Ruzivo rwehunyanzvi rweSoliqua 100/33

Ruzivo runotevera rwunopihwa varapi uye vamwe vashandi vezvehutano.

Zviratidzo

Soliqua 100/33 iri FDA-inogamuchirwa kuti ishandiswe pamwe nekudya uye kurovedza muviri kugadzirisa glycemic kutonga muvakuru vane mhando 2 chirwere cheshuga mellitus.

Nzira yekuita

Soliqua 100/33 mubatanidzwa we insulin glargine (basal insulin analog) uye lixisenatide (glucagon-yakaita peptide 1 [GLP-1] receptor agonist).

Insulin glargine inoderedza glucose yeropa nekuwedzera pheripheral glucose kutora uye kudzikisa kugadzirwa kweglucose kubva muchiropa. Lixisenatide inoderedza glucose yeropa nekuwedzera insulin kuchengetedzwa, kudzora glucagon kuchengetedza, uye kunonoka gastric kubuda.

Pharmacokinetics uye metabolism

Iyo insulin glargine-to-lixisenatide reshiyo haina zvainoita pa pharmacokinetics yechimwe chinhu.

Insulin glargine haina yepamusoro uye inogadziriswa zvishoma pa carboxyl terminus ye B cheni mune subcutaneous depot.

Nguva yekukwirisa max ye lixisenatide iri 2.5 kusvika maawa matatu. Lixisenatide ine 55 muzana protein inosunga rate uye inobviswa kuburikidza neweti uye kuwora kweproteolytic. Zvinoreva hafu-hupenyu ingangoita maawa matatu.

Contraindications

Soliqua 100/33 inopesana nevarwere:

• panguva yezvikamu zve hypoglycemic
• ine nhoroondo yeakanyanya hypersensitivity kune insulin glargine kana lixisenatide

Kuchengetedza

Soliqua 100/33 zvinyoreso zvinofanirwa kuchengetwa mufiriji, patembiricha iri pakati pe36 ° F uye 46 ° F (2 ° C uye 8 ° C), asi haina kumbobatwa nechando. Mushure mekushandisa kwekutanga, zvinyoreso zvinogona kuchengetwa pakushambidzika kwemukati 77 ° F (25 ° C). Vanofanira kuchengetedzwa kubva pachiedza. Rasa peni mushure memazuva makumi maviri nemasere kubva pakushandisa kwekutanga.

Disiki: MedicalNewsToday yaedza nepese painogona kuti ive nechokwadi chekuti ruzivo rwese nderwechokwadi, rwakakwana, uye rwechizvino-zvino. Nekudaro, chinyorwa ichi hachifanirwe kushandiswa sekutsiva ruzivo uye hunyanzvi hweane rezinesi rezvehutano. Iwe unofanirwa kugara uchibvunza chiremba wako kana imwe nyanzvi yehutano usati watora chero mushonga. Ruzivo rwezvinodhaka ruri pano runogona kuchinja uye haruna kuitirwa kufukidza ese mashandisirwo, madhairekitori, chenjedzo, kunyeverwa, kudyidzana kwezvinodhaka, allergic reaction, kana mhedzisiro. Kushaikwa kweyambiro kana rumwe ruzivo rwemushonga wakapihwa hakuratidze kuti mushonga kana musanganiswa wezvinodhaka wakachengeteka, unoshanda, kana wakakodzera kuvarwere vese kana kushandiswa kwese chaiko.