Munyori: Morris Wright
Zuva Rekusika: 25 Kubvumbi 2021
Gadziridza Zuva: 1 Kubvumbi 2025
Anonim
Thalidomide: The Chemistry Mistake That Killed Thousands of Babies
Vhidhiyo: Thalidomide: The Chemistry Mistake That Killed Thousands of Babies

Zvemukati

Thalidomide mushonga unoshandiswa kurapa maperembudzi chinova chirwere chinokonzerwa noutachiona hunokanganisa ganda nemitsipa, zvichikonzera kurasikirwa kwekunzwa, kushaya simba kwemhasuru uye kuoma mitezo. Uye zvakare, zvinokurudzirwawo kune varwere vane HIV uye lupus.

Mushonga uyu wekushandisa pamuromo, muchimiro chemapiritsi, unogona chete kushandiswa pakurudziro yechiremba uye unopesana zvachose nepamuviri uye unorambidzwa mumadzimai ezera rekubereka, pakati pemwedzi nekuguma kuenda kumwedzi, sezvo zvichitungamira mukukuvara kwemwana, sekushomeka kwemiromo, maoko nemakumbo, kuwanda kwenwe minwe, hydrocephalus kana kusashanda zvakanaka kwemoyo, ura neitsvo, semuenzaniso. Neichi chikonzero, mune kesi yekushandisa uyu mushonga kuchiratidzo chekurapa, nguva yebasa inofanirwa kusainwa.

Mutengo

Mushonga uyu unongobvumidzwa kushandiswa muchipatara uye unopihwa mahara nehurumende uye, nekudaro, hautengeswe muma pharmacy.


Zviratidzo

Iko kushandiswa kweThalidomide kunoratidzwa pakurapa:

  • Maperembudzi, inova chirwere chemaperembudzi cherudzi rwechipiri kana mhando erythema nodosum;
  • AIDS, nekuti inoderedza kupisa muviri, kushaya simba uye kushaya simba kwemhasuru:
  • Lupus, chinonamira-chinopesana-chinotakura chirwere, nekuti kuzvimba kunodzikira.

Kutanga kwekuita kwemushonga kunogona kusiyana pakati pemazuva maviri kusvika pamwedzi mitatu, zvinoenderana nechikonzero chekurapa uye inogona chete kushandiswa nevakadzi vasina zera rekuzvara uye muvana vanopfuura makore gumi nemaviri ekuberekwa.

Kushandisa sei

Iko kushandiswa kwemushonga uyu mumapiritsi kunogona kungotangwa pane kurudziro yechiremba uye mushure mekutevera yakatarwa protocol yekushandisa kwemushonga uyu unoda kuti murwere asaine fomu yekubvuma. Kazhinji, chiremba anokurudzira:

  • Kurapa kwemaperembudzi knotty mhando kana mhando II pakati pe100 kusvika 300 mg, kamwe pazuva, panguva yekurara kana zvirinani, 1 awa mushure mekudya kwemanheru;
  • Kurapa kwe elepromatous nodular ritema, tanga neanosvika 400 mg pazuva, uye udzikise madhizaini kwemavhiki maviri, kusvika wasvika padanho rekuchengetedza, riri pakati pe50 ne100 mg pazuva.
  • Kudzvinyirira chirwere, inosangana neHIV: 100 kusvika 200 mg kamwe pazuva pazuva rekurara kana 1 awa mushure mekudya kwekupedzisira.

Panguva yekurapwa munhu haafanire kunge aine hukama hwepedyo uye kana zvikaitika, nzira mbiri dzekudzivirira dzinofanirwa kushandiswa panguva imwechete, senge piritsi rekudzivirira, jekiseni kana kuiswa uye kondomu kana diaphragm. Uye zvakare, zvakakosha kuti utange kudzivirira kubata nhumbu mwedzi mumwe usati watanga kurapwa uye kweimwezve 4 vhiki mushure mekumiswa.


Kana vari varume vanoita zvepabonde nemadzimai ezera rekubereka, vanofanirwa kushandisa makondomu mune chero mhando yehukama hwepedyo.

Zvimwe zvinokanganisa

Mhedzisiro inowanzoitika yekushandisa mushonga uyu ndeyekuti kana ikashandiswa nemukadzi ane nhumbu, izvo zvinotungamira mukusagadzikana mumwana. Uye zvakare, inogona kukonzeresa kurira, kurwadziwa mumawoko, tsoka uye neuropathy.

Kusagadzikana kwepamuviri, kukotsira, dzungu, kupererwa neropa, leukopenia, leukemia, purpura, arthritis, kurwadziwa musana, kuderera kweropa, yakadzika tsinga thrombosis, angina, chirwere chemwoyo, kushungurudzika, kutya, sinusitis, kukosora, kurwadziwa kwepamuviri, manyoka, kana jeri zvakare kuitika. chibereko, conjunctivitis, yakaoma ganda.

Contraindications

Iko kushandiswa kwemushonga uyu kwakapesana zvachose pakuzvitakura nekuti kunokonzeresa kusanzwisisika mumwana, sekushayikwa kwemakumbo, maoko, miromo kana nzeve, kuwedzera mukusashanda kwemoyo, itsvo, ura uye chibereko, semuenzaniso.

Uye zvakare, makumi mana muzana evacheche vanofa vachangoberekwa uye zvakare zvinopesana panguva yekuyamwisa, nekuti mhedzisiro yacho haizivikanwe. Izvo zvakare haigone kushandiswa kana paine chisimbwa kune Thalidomide kana chimwe chezvinhu zvacho.


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