Munyori: Eugene Taylor
Zuva Rekusika: 16 Nyamavhuvhu 2021
Gadziridza Zuva: 17 Mbudzi 2024
Anonim
How to Inject Taltz
Vhidhiyo: How to Inject Taltz

Zvemukati

Chii chinonzi Taltz?

Taltz izita-zita mushonga mushonga. Inotenderwa kubata zvinotevera mamiriro:

Kune plaque psoriasis, Taltz inogona kupihwa vanhu vakuru uye vana vane makore matanhatu nemakore. Asi kune mamwe ese mamwe maitiro ayo anotenderwa, Taltz inogona kupihwa vanhu vakuru chete.


Taltz ine chinoshanda mushonga ixekizumab. Icho mhando yeiyo biologic chinodhaka (mushonga wakagadzirwa kubva kumasero mapenyu) unonzi humidized monoclonal antibody.

Taltz inouya nenzira mbiri: sirinji yakasarudzika uye chinyoreso chakanyora autoinjector. Mushonga unopihwa jekiseni pasi peganda rako (subcutaneous jekiseni). Anopa hutano hwako anokupa iwe jekiseni pakutanga. Ipapo vanogona kukudzidzisa maitiro ekuzvibaya iwe pachako kumba.

Kubudirira

Kuti uwane ruzivo nezve kugona kwaTaltz pakurapa mamiriro akanyorwa pamusoro, ona iyo "Taltz inoshandisa" chikamu pazasi.

Taltz generic

Taltz inowanikwa chete sezita-zita mushonga. Haisi ikozvino inowanikwa mune generic fomu. (Mushonga wegeneral ndiyo chaiyo kopi yemushonga unoshanda mune zita-zita mushonga.)

Taltz ine chinhu chinoshanda chemushonga chinodhaka: ixekizumab.

Taltz muyero

Iyo Taltz muyero unorayirwa nachiremba wako zvinoenderana nemamiriro ari kurapwa.

Ruzivo runotevera runotsanangura madosi ayo anowanzo shandiswa kana kukurudzirwa. Nekudaro, ita shuwa kutora dosi uye uteedzere iyo dosing chirongwa chiremba chaanoraira iwe.


Mafomu emishonga uye simba

Taltz inowanikwa mune rimwe simba: 80 milligrams pamamililita (mg / mL).

Mushonga uyu unouya nenzira mbiri: imwe-yekushandisa yakasarudzika sirinji uye imwechete-yekushandisa yakasarudzika autoinjector peni. Iwe unogona kuona kuti imwe fomu iri nyore kuti iwe ushandise kupfuura imwe iri. Taura nachiremba wako nezve iyo fomu yakakunakira iwe.

Mushonga unopihwa jekiseni pasi peganda rako (subcutaneous jekiseni). Anopa hutano hwako anokupa iwe jekiseni pakutanga. Ipapo vanogona kukudzidzisa maitiro ekuzvibaya iwe pachako kumba.

Dosage ye psoriatic arthritis

Kune psoriatic arthritis, yako yekutanga Taltz dosi ichapihwa semaviri majekiseni e80-mg (yehuwandu hwe160 mg) pazuva rimwe chete. Mushure meizvozvo, yako yekuchengetedza dosi ichave imwe 80-mg jekiseni kamwe chete pavhiki ina kwenguva yakareba sekurudzirwa nachiremba wako.

Ongorora: Kuti udzidze zvakawanda nezve psoriatic arthritis, ona iyo "Taltz inoshandisa" chikamu pazasi.

Chipimo chemushonga wepakati psori psoriasis

Kune plaque psoriasis, yako yekutanga Taltz dosi ichave maviri 80-mg majekiseni (ehuwandu hwe160 mg) pazuva rimwe chete. Mushure meizvozvo, iwe unenge uine 80-mg jekiseni kamwe chete pavhiki mbiri kwevhiki gumi nembiri. Ipapo yako yekuchengetedza dosi ichave imwe jekiseni kamwe chete pavhiki ina kwenguva yakareba sekurudzirwa nachiremba wako.


Ongorora: Kuti udzidze zvakawanda nezve plaque psoriasis, ona iyo "Taltz inoshandisa" chikamu pazasi.

Dosage ye psoriatic arthritis uye yakaenzana kune yakaoma plaque psoriasis

Kana iwe uine zvese zviri zviviri psoriatic arthritis uye plaque psoriasis, iwe unoshandisa iyo Taltz muyero uye dosing purogiramu yeapakati kusvika kune yakaoma plaque psoriasis. Ona chikamu chiri pamusoro apa kuti uwane ruzivo pamusoro peizvi.

Ongorora: Kuti udzidze zvakawanda nezve psoriatic arthritis uye plaque psoriasis, ona iyo "Taltz inoshandisa" chikamu pazasi.

Nhamba yeiyo isiri-radiographic axial spondyloarthritis

Kune isiri-radiographical axial spondyloarthritis (nr-axSpA), iwe unozogamuchira jekiseni ye80-mg yeTaltz kamwe chete pavhiki ina.

Ongorora: Kuti udzidze zvakawanda nezve nr-axSpA, ona iyo "Taltz inoshandisa" chikamu pazasi.

Dosage yeanoshanda ankylosing spondylitis

Nezve ankylosing spondylitis (AS), yako yekutanga Taltz dose ichave maviri 80-mg majekiseni (ehuwandu hwe160 mg) pazuva rimwe chete. Mushure meizvozvo, yako yekuchengetedza dosi ichave imwe 80-mg jekiseni kamwe chete pavhiki ina.

Ongorora: Kuti udzidze zvakawanda nezve AS, ona iyo "Taltz inoshandisa" chikamu pazasi.

Ko kana ndikapotsa dosi?

Ukatadza jekiseni, unofanirwa kuva naro nekukurumidza sezvazvinogona. Wobva wangotora jekiseni rako rinotevera kana zvaizokodzera. Asi kana ukapotsa jekiseni uye haina kutora nguva kusvikira yako inotevera yasvika, bvunza chiremba wako kuti akupe mazano pane zvekuita.

Kuti ubatsire kuve nechokwadi chekuti hauzorasikirwa nemushonga, edza kuseta chiyeuchidzo pafoni yako. Iyo yekurapa timer inogona kubatsira, zvakare.

Ndichada here kushandisa mushonga uyu kwenguva refu?

Taltz inofanirwa kushandiswa seyakareba kurapwa. Kana iwe nachiremba wako mukasarudza kuti Taltz inokushandirai zvakanaka, zvingangodaro kuti mucharamba muchiishandisa kwenguva yakareba.

Taltz mhedzisiro

Taltz inogona kukonzera zvinyoro kana zvakakomba mhedzisiro. Aya anotevera mazita ane zvimwe zvakakosha mhedzisiro mhedzisiro inogona kuitika uchitora Taltz. Rondedzero iyi haisanganisi mhedzisiro inogona kuitika.

Kuti uwane rumwe ruzivo nezve zvinogona kuitika mhedzisiro yeTaltz, taura nachiremba wako kana wemishonga. Ivo vanogona kukupa iwe matipi ekuti ungatarise sei nechero mhedzisiro mhedzisiro inogona kunetsa.

Ongorora: Chikafu neDrug Administration (FDA) inoteedzera mhedzisiro yemishonga iyo yaibvumidza. Kana iwe uchida kuzivisa kune iyo FDA mhedzisiro mhedzisiro iwe yawakave nayo neTaltz, unogona kuzviita kuburikidza neMedWatch.

Zvimwe zvakajairika mhedzisiro

Iyo inowanzoitika mhedzisiro mhedzisiro yeTaltz inogona kusanganisira:

  • jekiseni saiti maitiro (kutsvuka uye kushushikana kwakakomberedza nzvimbo yejekiseni)
  • zvirwere zvepamusoro zvekufema, senge dzihwa kana dzihwa
  • kusvotwa
  • fungal hutachiona, senge mutambi wemutsoka
  • conjunctivitis (pink ziso)

Mazhinji emhedzisiro iyi anogona kuenda mukati memazuva mashoma kana vhiki dzinoverengeka. Kana vakanyanya kuoma kana kuti vasingaendi, taura nachiremba wako kana wemishonga.

Yakakomba mhedzisiro

Matambudziko akakomba kubva kuTaltz haana kujairika, asi anogona kuitika. Fonera chiremba wako ipapo kana uine zvakakomba mhedzisiro. Fonera 911 kana zviratidzo zvako zvichinzwa kutyisidzira hupenyu kana kana iwe uchifunga kuti une emergency emergency.

Zvakakomba mhedzisiro, iyo inotsanangurwa zvakadzama pazasi mu "Side mhedzisiro mhedzisiro," inosanganisira:

  • kukanganiswa kweakanyanya kukanganiswa
  • chirwere chinoputira chirwere (IBD), chakadai seCrohn's disease kana ulcerative colitis
  • njodzi yakawedzera yehutachiona, senge tibhii (TB)

Zvikanganiso muvana

Chidzidzo chekiriniki chakatarisa kuvana vane makore matanhatu kusvika pamakore gumi nemasere avo vaive nemucherechedzo psoriasis. Muchidzidzo ichi, mhando dzemhedzisiro dzinoonekwa muvana uye kuti dzakaitika kangani dzakada kufanana neidzo dzinoonekwa muvakuru. Sezvakasiyana neizvi, zvinotevera mhedzisiro mhedzisiro yakaitika kazhinji muvana kupfuura muvakuru:

  • conjunctivitis (pink ziso)
  • dzihwa
  • mikoko (inopenya ganda kuputika)

Muchidzidzo chimwe chete ichi, chirwere cheCrohn chakaitika 0.9% zvakanyanya muvana vanotora Taltz pane zvaiitika kuvana vanotora placebo. (A placebo inorapa isina mushonga unoshanda.)

Rutivi mhedzisiro mhedzisiro

Iwe unogona kushamisika kuti kangani mamwe maratidziro anoitika nemushonga uyu, kana kuti kana mamwe maratidziro ane chekuita nezvawo. Heano mamwe emamwe madambudziko emushonga uyu unogona kana kusakonzera.

Allergic reaction

Sezvo nemishonga yakawanda, vamwe vanhu vanogona kuita zvinopesana nehutachiona mushure mokutora Taltz. Zviratidzo zvehunhu husina kugadzikana hunogona kusanganisira:

  • kuputika kweganda
  • kuvava
  • kuburitsa (kudziya uye kutsvuka mukati meganda rako)

Imwe yakanyanya kukonzeresa kusagadzikana isingawanzo asi inogoneka. Zviratidzo zveakanyanya kusagadzikana maitiro zvinogona kusanganisira:

  • angioedema (kuzvimba pasi peganda rako, kazhinji mumaziso ako, miromo, kana matama)
  • kuzvimba kwerurimi rwako, muromo, kana huro
  • kunetseka kufema
  • kuomesa pachipfuva
  • kunzwa kupera simba

Muzvidzidzo zvekiriniki, maitiro eergoriki akaitika mu0.1% kana pasi pevanhu vakagamuchira Taltz Izvi zvinokanganisa maitiro zvaisanganisira angioedema uye urticaria (kuputika kweganda kunonzwika zvakare kunzi mikoko).

Fonera chiremba wako ipapo kana iwe uine chirwere chakakomba chemuviri kuTaltz. Asi fonera 911 kana yako yemuno emergency emergency kana zviratidzo zvako zvichinzwa kutyisidzira hupenyu kana kana iwe uchifunga kuti une emergency emergency.

Jekiseni saiti yekuita

Iwe unogona kuve nekupindurwa kweganda munzvimbo iyo iwe yaunobaya madosi eTaltz. Uye izvi zvinogona kukonzera zviratidzo zvakaita sekutsvuka kana kurwadziwa.

Mune zvidzidzo zvemakiriniki, 17% yevanhu vane plaque psoriasis vakagamuchira Taltz vaive nemhinduro, senge kutsvuka kana kurwadziwa, panzvimbo yejekiseni. Mazhinji eaya maitiro aive akapfava kana akaenzana uye haana kukonzera kuti vanhu varege kurapwa.

Nguva imwe neimwe paunobaya Taltz, unofanirwa kusarudza imwe nzvimbo pamuviri wako pane jekiseni rekupedzisira. Kana iwe uine ganda rekuita iro rakakomba kana risingapere mumazuva mashoma, ona chiremba wako.

Kuwedzera kwengozi yezvirwere

Taltz inogona kunetesa immune system yako. Kana immune system yako isina kusimba zvakakwana kurwisa utachiona, ungangoita mukana wekutapukirwa.

Mune zvidzidzo zvemakiriniki, 27% yevanhu vane plaque psoriasis vakagamuchira Taltz kwemavhiki gumi nemaviri vakatapukirwa. Heano zvimwe zvezviongorori ’zvakawanikwa:

  • Mazhinji ezvirwere izvi aive akapfava. Chete 0,4% yehutachiona hwaifungidzirwa zvakakomba, senge pneumonia.
  • Hutachiona hwakajairika hwaive hutachiona hwekufema sekukosora, dzihwa, kana hutachiona.
  • Zvimwe hutachiona zvaisanganisira conjunctivitis (pink ziso) uye fungal hutachiona, senge yemuromo thrush kana yemutambi tsoka.
  • Muzvidzidzo izvi, zvikamu makumi maviri nezviviri kubva muzana zvevanhu vakagamuchira placebo (kurapwa pasina mushonga unoshanda) vakawanawo hutachiona.
  • Mune vanhu vakagamuchira kurapwa kweTaltz kwemavhiki makumi matanhatu, 57% vakawana hutachiona zvichienzaniswa ne32% vakagamuchira placebo.

Kuongorora uye kuongorora hutachiona

Kana iwe uine zviratidzo zvehutachiona, taura nachiremba wako kana wemishonga. Vanogona kukurudzira kurapwa. Zviratidzo zvezvirwere zvidiki zvinogona kusanganisira:

  • kupindwa nechando
  • kukosora
  • huro inorwadza
  • matsvuku uye anorwadza maziso
  • dzvuku uye dzinorwadza nzvimbo dzeganda
  • zvigamba zvichena mumuromo mako
  • kutsva kana kurwadziwa kana weti

Zvakakosha zvikuru kuona chiremba wako kana hutachiona husingajekese. Zvikasadaro, zvinogona kuve zvakakomba.

Usati watanga kurapwa naTaltz, chiremba wako anozotarisa chero hutachiona, senge tibhii (TB), chirwere chemapapu. Kana iwe uine chero zviratidzo zveTB panguva yekurapwa kwako, zvakakosha kufonera chiremba wako ipapo ipapo. Zviratidzo izvi zvinosanganisira:

  • kupindwa nechando
  • tsandanyama aches
  • kuonda pasina kuedza
  • kukosora kwakaipa kunogara kwemavhiki matatu kana kupfuura
  • kukosora ropa kana mhezi
  • kurwadziwa mubhokisi
  • husiku hweziya

Kudzivirira hutachiona panguva yekurapa kwaTaltz

Kuti ubatsire kudzivirira utachiona uchitora Taltz, geza maoko ako kazhinji. Zvakare, dzivisa kusangana padyo nevanhu vane hutachiona (kunyanya kukosora, dzihwa, kana dzihwa).

Uye bvunza chiremba wako kana paine majekiseni aunofanira kuwana usati watanga kutora Taltz. (Ona "Taltz uye rarama majekiseni" mu "Taltz kudyidzana" chikamu pazasi kuti udzidze zvimwe.)

Chirwere chekuputira ura

Kana iwe ukatora Taltz, pane njodzi diki yekuti iwe unogadzira hutachiona hwechirwere (IBD). IBD iboka rezvirwere zvinokonzeresa kuzvimba (kuzvimba) munzira yako yekugaya. Izvi zvirwere zvinosanganisira chirwere cheCrohn uye ulcerative colitis.

Kana iwe uchitova neBD, Taltz inogona kuita kuti iwedzere, asi izvi hazviwanzo. Mune zvidzidzo zvemakiriniki, chirwere cheCrohn chakaitika mu0.1% yevanhu vakagamuchira Taltz. Uye 0,2% yevanhu vakagashira Taltz vaive new kana kuwedzera ulcerative colitis.

Iwe unofanirwa kuona chiremba wako kana uine zvitsva kana kuwedzera zviratidzo zveBD. Izvi zvinogona kusanganisira:

  • kurwadziwa mudumbu rako (dumbu)
  • manyoka, ane kana asina ropa
  • kuonda

Kurera huremu kana kuonda (kwete mhedzisiro)

Kurera huremu uye kuonda hakuna kutaurwa muzvidzidzo zvekiriniki zveTaltz. Zvisinei, kuonda kunogona kuva chiratidzo chetiberculosis (TB) kana chirwere chinoputira ura (IBD). Uye aya mamiriro ese ari maviri anogona kuitika mhedzisiro yeTaltz. Saka kana ukarasa huremu uchitora Taltz, zvakakosha kuti uone chiremba wako.

Kana iwe uine chero zvinonetsa pamusoro pekurema kana kurasikirwa uremu, taura nachiremba wako.

Bvudzi kurasikirwa (kwete mhedzisiro)

Kurasikirwa kwebvudzi kwakange kusingaonekwe mumakiriniki ekudzidza eTaltz. Nekudaro, kurasikirwa kwebvudzi kunogona kuve mugumisiro weakakomba ganda remusoro psoriasis, chimiro cheplque psoriasis iyo inogona kurapwa naTaltz. Nekukwenya musoro wako kana kutora pachikero, unogona kudzura bvudzi rako.

Kana iwe uine hanya nezvekurasikirwa kwebvudzi, taura nachiremba wako.

Kushungurudzika (kwete mhedzisiro)

Kushungurudzika hakuna kutaurwa semhedzisiro mhedzisiro muzvidzidzo zvekiriniki zveTaltz. Zvisinei, kuora mwoyo kunowanzoonekwa kune vanhu vane psoriasis kana psoriatic arthritis, iyo Taltz inoshandiswa kurapa.

Imwe ongororo yakaongorora kuti Taltz yakakanganisa sei zviratidzo zvekushushikana mune vanhu vane psoriasis. Vatsvagiri vakaona kuti vangangoita makumi mana muzana yevanhu vakagamuchira Taltz kwemavhiki gumi nemaviri vakaporeswa kubva kuzviratidzo zvekuora mwoyo.

Zvirwere zveganda senge psoriasis zvinogona kuve nemhedzisiro yakakosha. Kana iwe uchinzwa kusuruvara, kushushikana, kana kushushikana, ita chokwadi chekutaura nachiremba wako nezvazvo. Dzimwe nguva kungokurukura zvako zvinokunetsa kunogona kubatsira. Asi kana chiremba wako achifunga kuti uri kushushikana, ungangoda kurapwa kwazviri. Izvi zvinogona kuuya nenzira yekurapa kwepfungwa kana mushonga.

Acne (kwete mhedzisiro)

Acne haina kutaurwa semhedzisiro mhedzisiro muzvidzidzo zvekiriniki zveTaltz. Zvisinei, mushure mekunge Taltz yabvumidzwa, vanhu vashoma vakataura [KD1] [AK2] vaine acne kana mapundu eganda. Asi idzi kesi dzaive shoma, uye hazvisi pachena kana Taltz akakonzera acne.

Psoriasis mishonga dzimwe nguva inoshandiswa kurapa rakakomba mhando yemakemikari, anonzi acne inversa (kana hidradenitis suppurativa). Imhaka yekuti acne inversa inosanganisira inorwadza, yakazvimba ganda, sekunge psoriasis.

Asi Taltz haisati yadzidziswa kune vanhu vane chero mhando yerudzi rweacne. Parizvino, iyo chete mishonga inogamuchirwa yekurapa acne inversa ndiHumira (adalimumab).

Kana iwe uine hanya nezve acne, taura nachiremba wako. Vanogona kuratidza nzira dzekubatsira kurapa.

Taltz mutengo

Sezvo nemishonga yese, mutengo weTaltz unogona kusiyana. Kuti uwane mitengo yazvino yeTaltz munharaunda yako, tarisa WellRx.com. Mari yaunowana paWellRx.com ndiyo yaunogona kubhadhara pasina inishuwarenzi. Mutengo chaiwo wauchabhadhara unoenderana nehurongwa hweinishuwarenzi, nzvimbo yauri, uye khemisi yaunoshandisa.

Mari uye inishuwarenzi rubatsiro

Kana iwe uchida rutsigiro rwemari kubhadhara Taltz, kana kana iwe uchida rubatsiro kuti unzwisise yako inishuwarenzi kufukidzwa, rubatsiro rwuripo.

Eli Lilly neKambani, iyo inogadzira Taltz, inopa kadhi rekuchengetedza uye chirongwa chekutsigira chinonzi Taltz Pamwechete. Kuti uwane rumwe ruzivo uye kuti uzive kana iwe uchikodzera rubatsiro, fonera 844-825-8966 kana shanyira iyo webhusaiti chirongwa.

Taltz inoshandisa

Chikafu neDrug Administration (FDA) inobvumidza mishonga yemishonga yakadai saTaltz kurapa mamwe mamiriro. Taltz inogona zvakare kushandiswa kure-chitaridzi kune mamwe mamiriro. Kunze-chitambi kushandiswa ndiko kana mushonga unobvumidzwa kurapa imwechete mamiriro unoshandiswa kurapa imwe mamiriro.

Taltz ye psoriatic arthritis

Taltz FDA-inogamuchirwa kurapa inoshanda psoriatic arthritis muvanhu vakuru.

Psoriatic arthritis chimiro cheArthritis umo imwe kana akawanda majoini anozvimba, anorwadza, uye akaomarara. Mamiriro acho anokura munenge makumi matatu muzana yevanhu vane psoriasis. Izvo zvakare zvinokwanisika kukudziridza psoriatic arthritis usati wawana psoriasis paganda rako.

Psoriatic arthritis kazhinji inobata majoini mune yako:

  • minwe
  • zvigunwe
  • mabvi
  • ankles
  • Ruoko
  • kudzika kumashure

Taltz inoderedza kuzvimba (kuzvimba) uye kurwadziwa mumajoini ako. Mushonga uyu unogona zvakare kuita kuti zvive nyore kwauri kufamba uye kuita mabasa ezuva nezuva, akadai sekupfeka, kuwacha, kudya, uye kufamba.

Kubudirira kwe psoriatic arthritis

Zvidzidzo zvekuchipatara zvakatarisa kuti Taltz akabata sei zviratidzo zvepsoriatic arthritis. Vatsvakurudzi vakaona kurwadziwa kwakataurwa nevanhu uye kuti vakapedza sei mabasa ezuva nezuva. Vatsvakurudzi vakafungawo kuti mangani majoini evanhu aive akapfava kana kuzvimba.

Mushure memavhiki makumi maviri nemana, Taltz akavandudza izvi zviratidzo ne:

  • kanokwana 20% mu53% kusvika 58% yevanhu
  • kanokwana 50% mu35% kusvika 40% yevanhu
  • 70% mu22% kusvika 23% yevanhu

Taltz yepakati kusvika kune yakaoma plaque psoriasis

Taltz iri FDA-inogamuchirwa kurapa zvine mwero kune zvakanyanya plaque psoriasis muvakuru uye vana vane makore matanhatu nemakore. Iyo yakakodzera kune vanhu avo psoriasis inogona kubatsirwa kubva kune systemic kurapwa (kurapa iyo inobata muviri wako wese) kana phototherapy (light kurapwa).

Plaque psoriasis ndiyo yakajairika fomu ye psoriasis. Inogona kubva pane yakapfava kusvika kune yakaoma. Chiremba wako anogona kukuudza kuti yakanyanya sei psoriasis yako uye kana Taltz yakakunakira iwe. Yako psoriasis inogona kukodzera kurapwa naTaltz kana:

  • une matanda (makobvu, matsvuku, makwapa makwapa) pane anopfuura 3% yemuviri wako
  • une mavara pamaoko ako, tsoka, kana sikarudzi
  • yako psoriasis inokanganisa zvakanyanya hupenyu hwako
  • mishonga iri yemusoro (yakashandiswa kuganda rako) haina kuunza psoriasis yako pasi pesimba

Taltz inobatsira kudzikisa huwandu hwe psoriasis plaque uye kuti yakaoma sei.

Kubudirira kweplate psoriasis muvakuru

Zvidzidzo zvekiriniki zvakatarisa kuti Taltz yakakanganisa sei zviratidzo zveplque psoriasis muvakuru vane makore gumi nemasere zvichikwira. Mushure memasvondo gumi nemaviri, Taltz akasunungura zviratidzo na:

  • kanokwana 75% mu 87% kusvika 90% yevanhu
  • 90% mu68% kusvika 71% yevanhu
  • 100% mu35% kusvika 40% yevanhu

Vatsvaguriri vakatarisawo mashandiro akaita Taltz muvanhu vane psoriasis zviratidzo zvainge zvasunungurwa, kana kuti zvaingova zvidiki, mushure memasvondo gumi nemaviri ekurapwa. Mushure memasvondo makumi matanhatu ekutora Taltz, 75% yevanhu ava vaive vachiri nezvishoma kana vasina psoriasis zviratidzo.

Uye muchidzidzo chekiriniki chebonde psoriasis, 73% yevanhu vakagashira Taltz vaingova nezviratidzo zvidiki kana zviratidzo zvavo zvabuda mushure memasvondo gumi nemaviri.

Kubudirira kweplate psoriasis muvana

Chidzidzo chekiriniki chakatarisa kuti Taltz yakakanganisa sei zviratidzo zveplque psoriasis muvana vane makore matanhatu kusvika gumi nemasere ekuberekwa. Mushure memasvondo gumi nemaviri, Taltz akasunungura zviratidzo na:

  • vangangoita 75% mu89% yevana
  • vangangoita 90% mu78% yevana
  • 100% mu50% yevana

Taltz yespondyloarthritis

Taltz FDA-inogamuchirwa kurapa maviri mafomu e spondyloarthritis (SA) muvakuru. Kunyanya, Taltz inogamuchirwa kurapa aya maviri mafomu eSA, ayo anotsanangurwa zvakadzama pazasi:

  • isiri-radiographic axial spondyloarthritis (nr-axSpA)
  • inoshanda ankylosing spondylitis (AS) kana radiographic axial spondyloarthritis (r-axSpA)

SA chirwere chinoputira uye chimiro cheArthritis chinokonzera kuzvimba mumuzongoza wako. Kazhinji, majoini epedyo anokanganiswawo, kunyanya iwo maviri majoini anobatanidza yako yepazasi musana kune yako pelvis (sacropelvic majoini). Kana kukuvara kwemajoini kusingaoneke pane maX-ray (radiographs), chimiro cheSA chinonzi nr-axSpA.

Kana SA ichifambira mberi, iko kusingaperi (kwenguva refu) kuzvimba kunogona kukonzera vertebrae mumuzongoza wako kuti isanganise pamwechete. Nekudaro, musana wako unozoita kushomeka. Kushungurudzika kumashure uye kuneta zviratidzo zvakajairika zveSA izvo zvakafambira mberi. Nemhando iyi yeSA, kubatana kwekukuvara kunogona kuoneka paX-ray. Iyi fomu yeSA inonzi inoshanda AS, kana r-axSpA.

Kubudirira kweasina-radiographic axial spondyloarthritis

Chidzidzo chekiriniki chakatarisa kune vakuru vane makore gumi nemasere uye vakuru ne nr-axSpA. Ichi chidzidzo chakatarisa kurapwa neTaltz zvichienzaniswa neyeye placebo (kurapwa pasina mushonga unoshanda).

Mushure memasvondo makumi mashanu nemaviri ekurapwa:

  • 30% yevanhu vanoshandisa Taltz vane zviratidzo zvavo zvakaderedzwa ne40% kana kupfuura. Zviratidzo izvi zvaisanganisira kuomarara mumajoini uye musana.
  • Mukuenzanisa, 13% yevanhu vanoshandisa iyo placebo vakave nemhedzisiro yakafanana.

Kubudirira kweanoshanda ankylosing spondylitis

Zvidzidzo zviviri zvemakiriniki zvakatarisa kuvanhu vakuru vane makore gumi nemasere kana kupfuura neAS inoshanda. Izvi zvidzidzo zvakatarisa kurapwa neTaltz zvichienzaniswa neyeye placebo.

Mushure memasvondo gumi nematanhatu ekurapwa:

  • 25% kusvika 48% yevanhu vanoshandisa Taltz vane zviratidzo zvavo zvakaderedzwa ne40% kana kupfuura. Zviratidzo izvi zvaisanganisira kuomarara mumajoini uye musana.
  • Mukuenzanisa, 13% kusvika 18% yevanhu vanoshandisa placebo vakave nemhedzisiro yakafanana.

Pamusoro pezvo, vanhu vakatora Taltz vaive nemarwadzo mashoma uye panyama vakanzwa zvirinani kana vachienzaniswa nevanhu vakatora placebo.

Taltz nevana

Taltz FDA-inogamuchirwa kurapa plaque psoriasis muvana vane makore matanhatu emakore uye zvichikwira. Kuti uwane ruzivo pamusoro pekushandisa uku, ona chikamu chiri pamusoro chinonzi "Taltz yepakati uye yakasimba psoriasis psoriasis."

Taltz yemamwe mamiriro

Pamusoro pekushandisa kwakanyorwa pamusoro, Taltz inogona kushandiswa kure-chitaridzi kune zvimwe zvinangwa. Kunze-chitambi kushandiswa kwemishonga ndiko apo mushonga unobvumidzwa kushandiswa kumwe chete uchishandiswa kune wakasiyana uyo usingatenderwe. Uye unogona kushamisika kana Taltz inoshandiswa kune mamwe mamiriro.

Taltz yerheumatoid arthritis (off-label kushandiswa)

Taltz haina kubvumidzwa kurapa rheumatoid arthritis (RA). Nekudaro, chiremba wako anogona kupa mushonga uyu asiri-chitaridzi kana mamwe marapirwo akatenderwa asina kukushandira.

RA chirwere umo immune yako inorwisa majoini ako, ichivaita kuzvimba, kuomarara, uye kurwadza. Tsvakurudzo dzinoverengeka dzakatarisa kana Taltz inogona kubatsira kubata RA. Taltz inoshanda pachikamu chedziviriro yezvirwere mumuviri chinozivikanwa kuti chinokonzera kumwe kuzvimba kwekubatana uku (kuzvimba).

Kuongororwa kwezvidzidzo kwakagumisa kuti Taltz yaive inoshanda pakurapa RA.

Kana iwe uchida kuziva zvakawanda nezve kushandisa Taltz kurapa RA, taura nachiremba wako.

Taltz yeosteoarthritis (kwete kushandiswa kwakakodzera)

Taltz haina kubvumidzwa kana kushandiswa kure-chitambi pakurapa osteoarthritis. Iyi fomu yeArthritis inokonzerwa nekusakara uye kubvarura pamajoini ako. Hazvina kukonzerwa kuzvimba. Saka osteoarthritis yaisazobatsirwa nemishonga, seTaltz, iyo inokanganisa immune system yako.

Kana iwe uine mibvunzo nezvesarudzo dzekurapa kweosteoarthritis, taura nachiremba wako.

Taltz uye doro

Doro haribate zvakananga kuti Taltz inoshanda sei, saka hapana yambiro chaiyo yekudzivirira doro panguva yekurapwa kweTaltz.

Nekudaro, kunwa doro kunogona kuwedzera psoriasis, iyo Taltz inoshandiswa kurapa.Pamusoro pezvo, doro rinogona kuita kuti kurapwa kweporioriasis kusanyanya kushanda uye kunogona zvakare kuita kuti immune system yako isakwanise kurwisa hutachiona.

Ikozvino nhungamiro yekurapa uye kugadzirisa psoriasis inokurudzira kudzora doro raunonwa.

Kana iwe ukanwa doro, bvunza chiremba wako kuti zvakadii zvakachengeteka kuti iwe ushandise uchitora Taltz.

Dzimwe nzira kuTaltz

Mimwe mishonga iripo inogona kurapa mamiriro ako. Zvimwe zvinogona kunge zvakakukodzera iwe kupfuura vamwe. Kana iwe uchifarira kutsvaga imwe nzira yeTaltz, taura nachiremba wako. Vanogona kukuudza nezvemimwe mishonga inogona kukushandira zvakanaka.

Ongorora: Mimwe yemishonga yakanyorwa pano inoshandiswa kure-chitaridzi kurapa aya chaiwo mamiriro.

Dzimwe nzira dzepsoriatic arthritis

Mienzaniso yemimwe mishonga inogona kushandiswa kurapa psoriatic arthritis inosanganisira:

  • methotrexate (Otrexup, Rasuvo, Trexall)
  • apremilast (Otezla)
  • infliximab (Remicade)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • tofacitinib (Xeljanz)
  • golimumab (Simponi)
  • certolizumab (Cimzia)
  • secukinumab (Cosentyx)
  • ustekinumab (Stelara)
  • brodalumab (Siliq)
  • guselkumab (Tremfya)
  • sulfasalazine (Azulfidine)

Ongorora: Kuti udzidze zvakawanda nezve psoriatic arthritis, ona iyo "Taltz inoshandisa" chikamu chiri pamusoro.

Dzimwe nzira dzekuenzanisira kune dzakasimba plaque psoriasis

Mienzaniso yemamwe madhiragi ayo anogona kushandiswa kurapa zvine mwero kusvika kune yakaoma plaque psoriasis inosanganisira:

  • apremilast (Otezla)
  • infliximab (Remicade)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • certolizumab (Cimzia)
  • ustekinumab (Stelara)
  • secukinumab (Cosentyx)
  • brodalumab (Siliq)
  • guselkumab (Tremfya)
  • golimumab (Simponi)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Ongorora: Kuti udzidze zvakawanda nezve plaque psoriasis, ona iyo "Taltz inoshandisa" chikamu chiri pamusoro.

Dzimwe nzira dze ankylosing spondylitis

Mienzaniso yemimwe mishonga inogona kushandiswa kurapa ankylosing spondylitis (AS) inosanganisira:

  • infliximab (Remicade)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • secukinumab (Cosentyx)
  • certolizumab (Cimzia)
  • golimumab (Simponi)
  • ustekinumab (Stelara)
  • brodalumab (Siliq)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Ongorora: Kuti udzidze zvakawanda nezve AS, ona iyo "Taltz inoshandisa" chikamu pamusoro.

Dzimwe nzira dzisiri-radiographic axial spondyloarthritis

Mienzaniso yemimwe mishonga inogona kushandiswa kurapa isiri-radiographic axial spondyloarthritis (nr-axSpA) inosanganisira:

  • certolizumab (Cimzia)
  • adalimumab (Humira)
  • secukinumab (Cosentyx)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Ongorora: Kuti udzidze zvakawanda nezve nr-axSpA, ona iyo "Taltz inoshandisa" chikamu chiri pamusoro.

Taltz vs.Cosentyx

Unogona kushamisika kuti Taltz inofananidzwa sei nemimwe mishonga inorayirwa kuti ishandiswe zvakafanana. Pano tinotarisa kuti Taltz neCosentyx zvakafanana uye zvakasiyana.

About

Taltz neCosentyx ese ari maviri biologic madhiragi (mishonga inogadzirwa kubva muzvikamu zvezvinhu zvipenyu). Vanoshanda nekutarisa chikamu chakati chedziviriro yako mumuviri.

Taltz ine mushonga ixekizumab, nepo Cosentyx iine mushonga secukinumab. Iyi mishonga miviri inonzi monoclonal antibodies. Ivo vanovhara chiitiko cheprotein mune yako immune system inonzi interleukin-17. Interleukin-17 inokonzeresa kuti immune system yako irwise maseru ari muganda rako uye majoini. Izvi zvinokonzeresa kuzvimba kunoonekwa nezvirwere senge plaque psoriasis, psoriatic arthritis, uye spondyloarthritis.

Zvishandiso

Chikafu neDrug Administration (FDA) yakabvumidza ese ari maviri Taltz neCosentyx kurapa zvine mwero kune zvakanyanya plaque psoriasis. Iyi mishonga inokodzera vanhu vane psoriasis vanogona kubatsirwa kubva pakurapa systemic (kurapa kunokanganisa muviri wako wese) kana phototherapy (light kurapwa).

Ye plaque psoriasis, Taltz inogamuchirwa kuti ishandiswe muvakuru uye vana vane makore matanhatu nemakore. Nekudaro, Cosentyx inogamuchirwa chete kuti ishandiswe kune vanhu vakuru vane mamiriro aya.

Ose maTaltz neCosentyx ari zvakare FDA-anotenderwa kurapa anoshanda psoriatic arthritis muvakuru. ("Kushanda" zvinoreva kuti parizvino une zviratidzo.)

Uye zvakare, ese ari maviri Taltz neCosentyx anotenderwa ekurapa asiri-radiographic axial spondyloarthritis uye anoshanda ankylosing spondylitis muvanhu vakuru.

Ongorora: Kuti uwane rumwe ruzivo nezve mamiriro ataurwa pano, ona iyo "Taltz inoshandisa" chikamu chiri pamusoro.

Mafomu emishonga uye manejimendi

Ose maTaltz neCosentyx anopiwa jekiseni pasi peganda rako (jekiseni rinotsvedza). Anopa hutano hwako anokupa iwe jekiseni pakutanga. Ipapo vanogona kukudzidzisa maitiro ekuzvipa iwe jekiseni kumba.

Taltz inouya nenzira mbiri: imwechete-yekushandisa yakasarudzika sirinji uye imwechete-yekushandisa yakasarudzika autoinjector peni.

Cosentyx inouya nenzira nhatu:

  • imwechete-shandisa Sensoready peni
  • imwe-yekushandisa yakasarudzika sirinji
  • gaba-rekushandisa kamwechete rinopihwa sejekiseni nemupi wako wezvehutano

Side migumisiro uye njodzi

Taltz neCosentyx zvinogona kukonzera mamwe akafanana mhedzisiro uye mamwe akasiyana. Pazasi pane mienzaniso yemhedzisiro iyi.

Zvimwe zvakajairika mhedzisiro

Aya mazita ane mienzaniso yemamwe mhedzisiro mhedzisiro anokwanisa kuitika neTaltz, neCosentyx, kana nezvose zviri zviviri zvinodhaka (kana zvichitorwa zvakasiyana).

  • Zvinogona kuitika naTaltz:
    • jekiseni saiti maitiro (kutsvuka uye kushushikana kwakakomberedza nzvimbo yejekiseni)
    • conjunctivitis (pink ziso)
  • Zvinogona kuitika neCosentyx:
    • manyoka
    • maronda emuromo
    • kuputika kweganda
  • Zvinogona kuitika nezvose Taltz neCosentyx:
    • fungal hutachiona, senge mutambi wemutsoka
    • zvirwere zvepamusoro zvekufema, senge dzihwa
    • kusvotwa

Yakakomba mhedzisiro

Iyi rondedzero ine mienzaniso yemhedzisiro mhedzisiro mhedzisiro inogona kuitika neese maviri Taltz neCosentyx (kana ikatorwa yega).

  • kuwedzera njodzi yehutachiona hunogona kunge hwakakomba, senge tibhii (TB)
  • nyowani kana kuwedzera kwechirwere chechirwere (IBD), senge chirwere cheCrohn kana ulcerative colitis
  • kukanganiswa kweakanyanya kukanganiswa

Kubudirira

Taltz neCosentyx vane akasiyana FDA-anotenderwa mashandisiro, asi iwo ari maviri anoshandiswa kurapa anotevera mamiriro:

  • zvine mwero kune zvakanyanya plaque psoriasis
  • psoriatic arthritis iri kushanda (parizvino ichikonzera zviratidzo)
  • isiri-radiographic axial spondyloarthritis
  • inoshanda ankylosing spondylitis

Iyi mishonga haina kuenzaniswa zvakananga muzvidzidzo zvekiriniki. Nekudaro, kumwe kuongorora kweye plaque psoriasis yakawana kuti Taltz yainyanya kushanda kupfuura Cosentyx pakudzora zviratidzo zve psoriasis.

Mirayiridzo yekurapa kubva muna2018 na2019 inokurudzira ese ari maviri madhiragi senzira dzevanhu vanoda kurapwa kweiyo psoriasis kana psoriatic arthritis. Biologics imhando yemushonga inotarisa zvikamu zvemuviri wako immune izvo zvinobatanidzwa mu psoriasis uye psoriatic arthritis.

Chiremba wako anogona kukurudzira biologic kana mamwe marapirwo asina kushanda zvakaringana. Semuenzaniso, biologic inogona kunge yakakunakira iwe kana:

  • une plaque psoriasis uye light therapy kana kurapwa kunoiswa paganda rako hakuna kushanda
  • une psoriatic arthritis uye anti-anogumbura marapiro (ayo anobatsira kudzora kuzvimba) senge marwadzo ekudzora kana maSteroid haana kushanda

Cosentyx inogona kunge iri nani pane Taltz yepaki psoriasis inobata zvipikiri. Taltz inogona kunge iri sarudzo iri nani ye erythrodermic psoriasis, iri isingawanzo mhando psoriasis.

Mariro

Taltz neCosentyx ese ari maviri zita-zita zvinodhaka. Ikozvino hapana mafomu akajairika eimwe mishonga. Brand-zita mishonga kazhinji inodhura kupfuura ejeniki.

Zvinoenderana nekufungidzira pa WellRx.com, Taltz neCosentyx zvinowanzoita mutengo zvakafanana. Mutengo chaiwo wauchabhadhara chero mushonga unobva pane yako inishuwarenzi chirongwa, kwaunogara, uye pharmacy yaunoshandisa.

Taltz vs. Humira

Pamusoro peCosentyx (pamusoro), Humira mumwe mushonga uyo unemamwe mashandisiro akafanana neayo eTaltz. Pano tinotarisa kuti Taltz naHumira vakafanana uye vakasiyana sei.

About

Taltz naHumira ese ari maviri biologic zvinodhaka (zvinodhaka zvakagadzirwa kubva muzvikamu zvezvinhu zvipenyu). Ivo vese vanoshanda nekutarisa zvakasiyana, asi zvakanangana, zvikamu zvemuviri wako.

Taltz ine ixekizumab, inova mhando yemushonga unonzi monoclonal antibody. Iyo inovhara chiitiko cheprotein mune immune system inonzi interleukin-17. Interleukin-17 inokonzeresa kuti immune system irwise maseru muganda nemajoini. Izvi zvinoguma nekuzvimba kunoonekwa nezvirwere senge plaque psoriasis, psoriatic arthritis, uye spondyloarthritis.

Humira ine adalimumab, inova mhando yemushonga unonzi tumor necrosis factor-alpha (TNF-α) blocker. Iyo inovhara chiitiko cheprotein inonzi TNF-α. Iyi protein inobatanidzwa mukukonzera kuzvimba mumamiriro akasiyana siyana, kusanganisira psoriasis uye psoriatic arthritis.

Zvishandiso

Chikafu neDrug Administration (FDA) yakabvumidza ese ari maviri Taltz naHumira kurapa zvine mwero kune zvakanyanya plaque psoriasis. Chiremba wako anogona kunyorera mumwe wemishonga iyi kana psoriasis yako ichibatsirika kubva pakurapa systemic (kurapa kunokanganisa muviri wako wese) kana phototherapy (kurapa kwakareruka).

Ye plaque psoriasis, Taltz inogamuchirwa kuti ishandiswe muvakuru uye vana vane makore matanhatu nemakore. Nekudaro, Humira inogamuchirwa chete kuti ishandiswe muvakuru vane mamiriro aya.

Ose maTaltz naHumira zvakare ari FDA-anotenderwa kurapa anoshanda psoriatic arthritis muvakuru. ("Kushanda" zvinoreva kuti parizvino une zviratidzo.)

Uye zvakare, ese ari maviri Taltz naHumira anotenderwa ekurapa anoshanda ankylosing spondylitis muvanhu vakuru. Asi chete Taltz ndiyo inogamuchirwa yekurapa isiri-radiographic axial spondyloarthritis muvanhu vakuru.

Humira zvakare ane FDA mvumo yekurapa inotevera mamiriro:

  • rheumatoid arthritis (RA)
  • zvine mwero kusvika pakukutu kwevechidiki idiopathic arthritis
  • Chirwere cheCrohn
  • zvine mwero kusvika zvakanyanya ulcerative colitis
  • hidradenitis suppurativa, inorwadza ganda mamiriro anonziwo acne inversa
  • mamwe marudzi eininfectious uveitis (rudzi rwekuzvimba kwemaziso), kusanganisira wepakati uveitis, posterior uveitis, uye panuveitis

Ongorora: Kuti udzidze zvakawanda nezve mamiriro Taltz anotenderwa kurapa, ona iyo "Taltz inoshandisa" chikamu chiri pamusoro.

Mafomu emishonga uye manejimendi

Taltz naHumira vese vanopihwa jekiseni pasi peganda rako (jekiseni rinotsvedza). Anopa hutano hwako anokupa iwe jekiseni pakutanga. Ipapo vanogona kukudzidzisa maitiro ekuzvipa iwe jekiseni kumba.

Taltz inouya nenzira mbiri: imwechete-yekushandisa yakasarudzika sirinji uye imwechete-yekushandisa yakasarudzika autoinjector peni.

Humira anouya nenzira nhatu:

  • chinyoreso-chinoshandiswa chinyoreso
  • imwe-yekushandisa yakasarudzika sirinji
  • gaba-rekushandisa kamwechete rinopihwa sejekiseni nemupi wako wezvehutano

Side migumisiro uye njodzi

Taltz naHumira vanogona kukonzera mamwe akafanana mhedzisiro uye mamwe akasiyana. Pazasi pane mienzaniso yemhedzisiro iyi.

Zvimwe zvakajairika mhedzisiro

Aya mazita ane mienzaniso yemamwe maitiro anowanzoitika anogona kuitika neTaltz, naHumira, kana nemishonga iyi miviri (kana ikatorwa zvakasiyana).

  • Zvinogona kuitika naTaltz:
    • tinea fungal hutachiona, senge tsoka yemutambi
    • conjunctivitis (pink ziso)
  • Zvinogona kuitika naHumira:
    • kutemwa nemusoro
    • mapundu
  • Zvinogona kuitika pamwe chete naTaltz naHumira:
    • jekiseni saiti saiti, senge kutsvuka uye kushushikana kwakakomberedza nzvimbo yejekiseni
    • zvirwere zvepamusoro zvekufema, senge dzihwa
    • kusvotwa

Yakakomba mhedzisiro

Aya mazita ane mienzaniso yezvakakomba mhedzisiro inogona kuitika naTaltz, naHumira, kana nezvose zviri zviviri zvinodhaka (kana zvichitorwa zvakasiyana).

  • Zvinogona kuitika naTaltz:
    • nyowani kana kuwedzera kwechirwere chechirwere (IBD), senge chirwere cheCrohn kana ulcerative colitis
  • Zvinogona kuitika naHumira:
    • matambudziko echiropa, akadai sekutadza kwechiropa
    • matambudziko ehurongwa hwemitsipa, senge multiple sclerosis (MS)
    • matambudziko eropa, senge akaderedzwa manhamba emasero matsvuku eropa, machena masero eropa, kana maplatelet
    • kutadza kwemoyo
    • fungal hutachiona, senge histoplasmosis
    • kuwedzera njodzi yemamwe kanzira, senge kenza yeganda, leukemia, uye lymphoma
    • nyowani kana kuwedzera psoriasis
  • Zvinogona kuitika pamwe chete naTaltz naHumira:
    • kuwedzera njodzi yehutachiona hunogona kunge hwakakomba, senge tibhii (TB)
    • kukanganiswa kweakanyanya kukanganiswa

Kubudirira

Taltz naHumira vane akasiyana FDA-anotenderwa mashandisiro, asi iwo ari maviri anoshandiswa kurapa anotevera mamiriro:

  • zvine mwero kune zvakanyanya plaque psoriasis
  • inoshanda psoriatic arthritis
  • inoshanda ankylosing spondylitis

Iyi mishonga haina kuenzaniswa zvakananga muvanhu vane plaque psoriasis, asi zvidzidzo zvakawana zvese Taltz naHumira kuti vabatsire pakurapa mamiriro aya.

Imwe kiriniki yekudzidza yakatarisa zvese Taltz naHumira mune vanhu vane psoriatic arthritis inoshanda. Mushure memasvondo makumi maviri nemana, psoriatic arthritis zviratidzo zvakadzikiswa neinosvika makumi maviri muzana mu58% kusvika 62% yevanhu vakatora Taltz. Izvi zvakafananidzwa ne57% yevanhu vakatora Humira uye 30% vakatora placebo (hapana kurapwa).

Mirayiridzo yekurapa kubva ku2018 na2019 inokurudzira ese ari maviri madhiragi senzira dzevanhu vanoda biologic kurapwa kweporiyo kana psoriatic arthritis. Biologics imhando yemushonga inotarisa zvikamu zvemuviri wako immune izvo zvinobatanidzwa mu psoriasis uye psoriatic arthritis.

Chiremba wako anogona kukurudzira biologic kana mamwe marapirwo asina kushanda zvakaringana. Semuenzaniso, biologic inogona kunge yakakunakira iwe kana:

  • une plaque psoriasis uye light therapy kana kurapwa kunoiswa paganda rako hakuna kushanda
  • une psoriatic arthritis uye anti-anogumbura marapiro (ayo anobatsira kudzora kuzvimba) senge marwadzo ekudzora kana maSteroid haana kushanda

Kune vanhu vazhinji vari kutanga kurapwa kweiyo inoshanda psoriatic arthritis, iwo 2018 nhungamiro inokurudzira kushandisa TNF-alpha blockers (senge Humira) pamusoro pe interleukin-17 blockers (senge Taltz). Iyo 2019 nhungamiro inotaura kuti Humira anogona zvakare kuve ari nani pane Taltz yepaki psoriasis inobata ganda romusoro uye erythrodermic psoriasis (rudzi rwusingawanzoitika rwe psoriasis).

Chidzidzo chekiriniki chakaenzanisa mashandiro anoita Taltz naHumira pakurapa psoriatic arthritis uye plaque psoriasis. Chidzidzo ichi chakataura kuti pamusoro pemasvondo makumi maviri nemana ekurapwa, makumi matatu muzana yevanhu vakatora Taltz zviratidzo zvavo zvakavandudzika neinosvika makumi mashanu muzana. Mukuenzanisa, 28% yevanhu vakatora Humira vaive nezviratidzo zvavo zviri nani neinenge 50%.

Mariro

Taltz naHumira vese vari vaviri vane zita-zita zvinodhaka. Ikozvino hapana mafomu akajairika eimwe mishonga. Brand-zita mishonga kazhinji inodhura kupfuura ejeniki.

Zvinoenderana nekufungidzira paWellRx.com, Taltz naHumira zvinowanzoita mutengo zvakafanana. Mutengo chaiwo wauchabhadhara chero mushonga unobva pane yako inishuwarenzi chirongwa, kwaunogara, uye pharmacy yaunoshandisa.

Taltz kudyidzana

Taltz inogona kusangana nemimwe mishonga. Kukurukurirana kwakasiyana kunogona kukonzera mhedzisiro. Semuenzaniso, kumwe kudyidzana kunogona kukanganisa mashandiro anoita mushonga. Kumwe kudyidzana kunogona kuwedzera mhedzisiro kana kuita kuti ive yakaoma.

Taltz nemimwe mishonga

Pazasi pane runyorwa rwemishonga inogona kusangana naTaltz. Urongwa urwu hauna mishonga yose inogona kuwirirana naTaltz.

Usati watora Taltz, taura nachiremba wako uye wemishonga. Vaudze nezvese zvinyorwe, pamusoro-pe-counter, uye mimwe mishonga yaunotora. Vaudzewo nezve chero mavitamini, mahebhu, uye zvinowedzera zvaunoshandisa. Kugovera ruzivo urwu kunogona kubatsira iwe kudzivirira kusangana kunogona kuitika.

Kana iwe uine mibvunzo nezve kudyidzana kwezvinodhaka zvinogona kukukanganisa, bvunza chiremba wako kana wemishonga.

Taltz uye warfarin

Warfarin (Coumadin, Jantoven) imhando yeropa rakatetepa, mushonga unobatsira kudzivirira kugwamba kweropa. Kutora Taltz newarfarin kunogona kuita kuti warfarin yako isanyanya kushanda.

Kana iwe uri kutora warfarin, chiremba wako angangoda kuongorora kuti zvinotora nguva yakareba sei kuti ropa rako rigadzike mushure mekunge watanga Taltz, panguva yekurapwa kwako, uye kana ukamira Taltz. Ivo vanogona kugadzirisa yako muyero wewarfarin kana zvichidikanwa.

Taltz uye cyclosporine

Cyclosporine imushonga unodzivirira muviri. Iwe unozvitora kuti uderedze mashandiro e immune system yako. Kutora Taltz ne cyclosporine kunogona kuita kuti cyclosporine yako isanyanya kushanda.

Kana iwe uri kutora cyclosporine, chiremba wako angangoda kutarisa huwandu hwemushonga muropa rako mushure mekunge watanga Taltz, panguva yekurapa kwako uye kana ukamira Taltz. Ivo vanogona kugadzirisa yako muyero we cyclosporine kana zvichidikanwa.

Cyclosporine inowanikwawo seinotevera mazita ezita rezita:

  • Cequa
  • Gengraf
  • Neoral
  • Restasis
  • Sandimmune

Taltz uye rarama majekiseni

Kuwana mushonga wekurarama paunenge uchitora Taltz kunogona kukonzera hutachiona hwakakomba.

Kurarama majekiseni anodzivirira mafomu ehutachiona kana mabhakitiriya, asi haakonzere hutachiona muvanhu vane immune immune system. Nekudaro, majekiseni anorarama anogona kukonzera hutachiona muvanhu vane immune system inokanganiswa nekurapwa neTaltz.

Paunenge uchitora Taltz, haufanire kuwana majekiseni ehupenyu akadai se:

  • chikeni pokisi
  • yero fever
  • TB (TB)
  • gwirikwiti, mamota, uye rubella (MMR)

Zvakanaka kuwana majekiseni asingashandi (kwete kurarama), akadai sefuru inopfura, panguva yekurapa kwako Taltz. Zvisinei, majekiseni asingashandi anogona kusashanda sezvaanowanzoita. (Mishonga yekudzivirira zvirwere inoshanda nekukonzeresa kuti immune system yako ibudise masoja ekudzivirira hutachiona anobatsira kurwisa hutachiona. Taltz inogona kuita kuti immune system yako isakwanise kugadzira masoja ekudzivirira chirwere.

Kana chiremba wako achida kuti utore Taltz, bvunza kana iwe uchikwanisa kufambidzana nezvose zvinokurudzirwa majekiseni.

Taltz nemishonga uye zvinowedzera

Iko hakuna chero mahebhu kana zvinowedzera izvo zvakanyatsotaurwa kuti zvinofambidzana naTaltz. Asi ita chokwadi chekutarisa nachiremba wako usati washandisa chero.

Maitiro ekutora Taltz

Mushonga unopihwa jekiseni pasi peganda rako (subcutaneous jekiseni). Anopa hutano hwako anokupa iwe jekiseni pakutanga. Ipapo vanogona kukudzidzisa maitiro ekuzvipa iwe jekiseni kumba. Iwe unogona kutora yako Taltz jekiseni chero nguva yezuva pazuva iro rakakodzera.

Taltz inouya seyadhi-imwe yakasarudzwa sirinji uye seyese-yekushandisa yakasarudzika autoinjector peni. Kumbira chiremba wako izvo zvakakunakira iwe. Mafomu ese ari maviri ane imwe chete dosi. Iwe jekiseni iro rakazara dosi uye wozorasa sirinji kana autoinjector peni.

Nguva yekutora

Kana iwe uchizoda kutora madosi eTaltz zvinoenderana nemamiriro ari kurapwa. Kazhinji, iwe uchagamuchira yako yekutanga dosi yeTaltz kuhofisi yechiremba wako. Ipapo unozogona kupa anotevera majekiseni kwauri.

Pazasi, isu tinotsanangura zvakajairika dosing mashedhi eTaltz pamashandisirwo ayo anotenderwa.

  • Kana iwe uine psoriasis: Pamutero wako wekutanga weTaltz, unozogamuchira majekiseni maviri pazuva rimwe chete. Mushure mekutanga kweiyo Taltz, iwe unenge uine jekiseni rimwe chete kwega kwevhiki mbiri kwevhiki gumi nembiri. Izvi zvichateverwa nejekiseni rimwe chete pamasvondo mana ese sekureba sekurudzirwa nachiremba wako.
  • Kana iwe uine psoriatic arthritis: Pamutero wako wekutanga weTaltz, unozogamuchira majekiseni maviri pazuva rimwe chete. Mushure mekutanga kweiyo Taltz, iwe unenge uine jekiseni rimwe chete kwega kwevhiki ina kwenguva yakareba sekurudzirwa nachiremba wako.
  • Kana iwe uine psoriasis uye psoriatic arthritis: Iwe uchagamuchira maTaltz doses anoenderana neyakakurudzirwa dosing purogiramu ye psoriasis, iyo inotsanangurwa pamusoro.
  • Kana iwe usina-radiographic axial spondyloarthritis (nr-axSpA): Mushure meyero yako yekutanga yeTaltz, iwe unenge uine jekiseni rimwe chete masvondo mana.
  • Kana iwe uine ankylosing spondylitis inoshanda (AS): Pamutero wako wekutanga weTaltz, unozogamuchira majekiseni maviri pazuva rimwe chete. Mushure mekutanga kweiyo Taltz, iwe unenge uine jekiseni rimwe chete masvondo mana.

Kuti Taltz ishande zvakanaka, zvakakosha kuitora sekurairwa nachiremba wako. Kuti uve nechokwadi chekuti unorangarira kutora mushonga, izano rakanaka kunyora yako jekiseni purogiramu pakarenda. Iwe unogona zvakare kushandisa mushonga wekuyeuchidza chishandiso kuti iwe usakanganwe.

Ongorora: Kuti uwane rumwe ruzivo nezve mamiriro akanyorwa pano, ona iyo "Taltz inoshandisa" chikamu chiri pamusoro.

Jekiseni

Anopa hutano hwako anokuraira maitiro ekushandisa iyo sirinji kana autoinjector peni. Kuti uwane rumwe ruzivo, mavhidhiyo, uye mifananidzo yemirayiridzo yejekiseni, ona webhusaiti yemugadziri.

Ramba uchifunga kuti nzvimbo dzakakodzera kubaya Taltz dziri kumberi kwezvidya zvako kana dumbu rako (dumbu). Iwe unogona zvakare kushandisa kumashure kwemaoko ako epamusoro, asi ungangoda mumwe munhu kuti akupe jekiseni.

Mashandiro anoita Taltz

Psoriasis, psoriatic arthritis, uye spondyloarthritis mamiriro e autoimmune. Zvinokonzera immune system yako (muviri wako kuzvidzivirira pachirwere) kurwisa maseru ane hutano nekukanganisa.

Kuti uwane rumwe ruzivo nezve aya mamiriro, ona iyo "Taltz inoshandisa" chikamu chiri pamusoro.

Zvikamu zvakasiyana zve immune immune zvinobatanidzwa mune yega yeaya mamiriro. Imwe nzira chaiyo ine chekuita neprotein inonzi interleukin-17A. Iyi protein inotaurira immune system yako kuti irwise maseru ari muganda rako uye majoini.

Taltz ine ixekizumab, iri mhando yechirwere inonzi humanized monoclonal antibody. Inoshanda nekusunga (kubatanidza) kune interleukin-17A. Nekuita izvi, Taltz inovhara kuita kweprotein. Inoimisa kubva kuudza immune system yako kuti irwise maseru ari muganda rako uye majoini.

Nekudzivirira immune system yako kubva pakurwisa maseru, Taltz inobatsira:

  • kuderedza kuumbwa kwemapareti paganda rako muplate psoriasis
  • kuderedza kuzvimba (kuzvimba) kwemajoini ako mu psoriatic arthritis, isiri-radiographic axial spondyloarthritis, uye anoshanda ankylosing spondylitis

Zvinotora nguva yakareba sei kuti zvishande?

Taltz inotanga kushanda uchangotanga kurapwa. Zvisinei, zvingangotora mavhiki mashoma kuti iwe uone chero shanduko.

Mune zvidzidzo zvemakiriniki, vanhu vazhinji vane plaque psoriasis vaive nerakajeka kana rinenge rakajeka ganda vhiki gumi nemaviri mushure mekunge vatanga kurapwa kana nekukurumidza. Uye vangangoita hafu yevanhu vane psoriatic arthritis vakatora Taltz vaive nezviratidzo zvishoma zvakanyanya uye zvirinani mashandiro emuviri nemavhiki gumi nemaviri mushure mekutanga kwekurapwa.

Chidzidzo chekiriniki chevakuru vasina-radiographic axial spondyloarthritis vakatarisa kurapwa neTaltz uye kurapwa ne placebo. (A placebo inorapa isina mushonga unoshanda.) Mushure memasvondo makumi mashanu nemaviri ekurapwa, makumi matatu muzana yevanhu vanoshandisa Taltz zviratidzo zvavo zvakadzikiswa ne40% zvimwe. Mukuenzanisa, 13% yevanhu vanoshandisa iyo placebo vakave nemhedzisiro yakafanana.

Zvidzidzo zviviri zvemakiriniki zvevakuru vane ankylosing spondylitis inoshanda vakatarisa kurapwa naTaltz zvichienzaniswa neiyo yenzvimbo inonyorwa. Mushure memasvondo gumi nematanhatu ekurapwa, 25% kusvika 48% yevanhu vanoshandisa Taltz zviratidzo zvavo zvakaderedzwa ne40% kana kudarika. Mukuenzanisa, 13% kusvika 18% yevanhu vanoshandisa placebo vakave nemhedzisiro yakafanana.

Taltz uye nhumbu

Taltz haisati yadzidzwa mumadzimai akazvitakura, saka hazvizivikanwe kana mushonga uyu wakachengeteka kutora panguva yekuzvitakura.

Iva nechokwadi chekuudza chiremba wako kana iwe uri nepamuviri kana uri kuronga kubata pamuviri usati watanga kurapwa. Kana iwe uchifunga kuti unogona kuve nepamuviri uchitora Taltz, taura nachiremba wako ipapo.

Taltz uye kuberekwa

Hazvizivikanwe kana Taltz yakachengeteka kutora panguva yekuzvitakura. Kana iwe uchiita bonde uye iwe kana mumwe wako muchigona kuve nepamuviri, taura nachiremba wako nezvezvido zvako zvekuberekwa paunenge uchishandisa Taltz.

Kuti uwane rumwe ruzivo nezve kutora Taltz panguva yepamuviri, ona iyo "Taltz nepamuviri" chikamu chiri pamusoro.

Taltz uye kuyamwisa

Hazvizivikanwe kana Taltz inopinda mumukaka wemukaka wevanhu kana kuti iyo inokanganisa maitiro anoita muviri wako mukaka wemuzamu. Taltz yakawanikwa mumukaka wemukaka muzvidzidzo zvemhuka, asi zvidzidzo zvemhuka hazviwanzo kuratidza zvichaitika muvanhu.

Kana iwe uchiyamwisa uye uchifunga kutora Taltz, taura nachiremba wako. Ivo vanogona kukurukura zvinogona kuitika njodzi uye mabhenefiti emushonga newe.

Mibvunzo yakajairika nezve Taltz

Heano mhinduro kumimwe mibvunzo inowanzo bvunzwa nezve Taltz.

Taltz ndeye biologic here?

Ehe. Taltz mishonga biologic. Izvi zvinoreva kuti mushonga unogadzirwa nemaprotein uye kwete kubva kumakemikari (sezvakaita mishonga yakawanda). Biologic zvinodhaka zvinogadzirwa murabhu uchishandisa maseru emhuka.

Ndicharamba ndichingoda kushandisa mafuta ekumusoro psoriasis ndichishandisa Taltz?

Pamwe. Asi iwe unofanirwa kutevera kuraira kwechiremba wako maererano neizvi.

Kana ganda rako rikachenesa zvachose mushure mekutora Taltz, saka haufanire kuramba uchishandisa mishonga yekurapa. Asi mune dzimwe nguva, iwe unogona kunge uchinge uine mamwe ma psoriasis plaque (gobvu, tsvuku, makanda makanda paganda rako). Kana izvi zvikaitika, chiremba wako anogona kukurudzira kuti iwe urambe uchishandisa zvinodzora kana zvimwe zvekurapa zvemusoro pazvinenge zvichidikanwa. Nguva dzose tevera rairo iyo chiremba wako anokupa iwe.

Kushandisa Taltz kunogona kukonzera nyowani kana kuwedzera hutachiona hwechirwere?

Hongu inogona, kunyange izvi zvisingawanzoitiki. Inflammatory bowel disease (IBD) iboka rezvirwere zvinokonzeresa kuzvimba (kuzvimba) munzira yako yekugaya. Izvi zvirwere zvinosanganisira chirwere cheCrohn uye ulcerative colitis.

Mune zvidzidzo zvemakiriniki, chirwere cheCrohn chakaitika mu0.1% yevanhu vane plaque psoriasis vakagamuchira Taltz. Ulcerative colitis yakaitika mu0.2% yevanhu vane plaque psoriasis vakagamuchira Taltz.

Kana uine zviratidzo zvitsva kana kuwedzera zveBD, ona chiremba wako. Zviratidzo zvinogona kusanganisira kurwadziwa mudumbu rako (mudumbu), manyoka uine kana usina ropa, uye kuonda.

Chii chandingaite kudzivirira hutachiona ini ndichitora Taltz?

Taltz inogona kushomeka chikamu chemuviri wako, saka mushonga unogona kuwedzera mukana wako wekutapukirwa. Heano mamwe matipi ekubatsira kuchengeta immune system yako yakasimba uye kukubatsira kudzivirira utachiona:

  • Usati watanga kurapwa, taura nachiremba wako nezve kusimuka kufambidzana nechero mishonga inokurudzirwa.
  • Shamba maoko ako nguva dzose, kunyanya kana wanga uri munzvimbo yeruzhinji.
  • Edza kudzivisa kusangana nevanhu vane hutachiona, kunyanya kukosora, dzihwa, kana dzihwa.
  • Dzivisa kugovana matauro kana kuwacha masaga nemumwe munhu ane fungal ganda hutachiona kana kutonhora kurwadziwa.
  • Idya kudya kunovaka muviri.
  • Wana nguva yakakwana yokurara.
  • Usapute.

Taltz inoporesa plaque psoriasis kana psoriatic arthritis?

Kwete, Taltz hairape aya mamiriro. Parizvino hapana mushonga weplata psoriasis kana psoriatic arthritis. Asi kurapwa kwenguva refu neTaltz kunogona kubatsira kudzora zviratidzo zvemamiriro aya.

Zvidzidzo zvekiriniki zvakaongorora vanhu vane plaque psoriasis avo vakatora Taltz. Zvimwe zviratidzo zvevanhu zvakajekeswa zvachose kana kuita zvidiki mushure memasvondo gumi nemaviri. Hafu yeboka iri rakazotora Taltz kwemamwe mavhiki makumi mana nemasere. Imwe hafu yeboka yakatora placebo (pasina kurapwa) kwemavhiki makumi mana nemasere.

Pakati pevanhu vakaramba vachitora Taltz, 75% vachiri vasina kana kungova nezviratidzo zvidiki pakupera kwechidzidzo. Kune vazhinji vevanhu vakatora placebo, zviratidzo zvavo zvakatonyanya zvakare. Chete 7% yeboka re placebo rakanga risina kana zviratidzo zvidiki. Ivhareji yenguva yakatora kuti zviratidzo zviwedzere kuipa muvanhu vakatora placebo aive mazuva zana nemakumi matanhatu nemana. Asi pavakatangazve kutora Taltz, ye66% yevanhu ava, yavo psoriasis yakajekeswa mukati memasvondo gumi nemaviri.

Taltz matanho

Usati watora Taltz, taura nachiremba wako nezve nhoroondo yako yehutano. Taltz inogona kunge isingave yakakunakira iwe kana uine mamwe marapirwo. Izvi zvinosanganisira:

  • Chero hutachiona, asi tibhii kunyanya. Taltz inogona kuita kuti immune system yako isakwanisa kurwisa utachiona, saka hutachiona hwakaita setibhii (TB) hunogona kukomba.
    • Kana iwe uine TB kana uine TB kare, ungangoda kutora mishonga kuti urape. Kana TB yarapwa, unogona kutanga kutora Taltz.
    • Kana iwe uine zviratidzo zvehumwe hutachiona, senge fivhiri, kana kana iwe ukawana hutachiona hunoramba huchidzoka, udza chiremba wako. Zvirwere izvi zvinogona kuda kurapwa usati watanga kurapwa naTaltz.
  • Chirwere chekuputira ura. Muzviitiko zvisingawanzoitika, Taltz inogona kukuvadza zviratidzo zvekuputira hutachiona chirwere (IBD). IBD iboka rezvirwere zvinosanganisira Crohn's disease uye ulcerative colitis. Kana uine IBD, taura nachiremba wako. Vanogona kuongorora zviratidzo zvako iwe uchitora Taltz. Kana IBD yako ikawedzera kuipa, ungangoda kumisa Taltz. Kune mimwe biologic mishonga isingatonyanya kukuvadza IBD iwe yaunogona kuedza.

Ongorora: Kuti uwane rumwe ruzivo nezve zvingangoitika zvakaipa zveTaltz, ona iyo "Taltz mhedzisiro" chikamu pamusoro.

Taltz kudarika

Imwe neimwe sirinji yakasarudzika uye autoinjector peni ine chaiyo chaiyo huwandu hwemishonga yemumwe mushonga. Saka kuwandisa kunogoneka chete kana ukazvipa majekiseni akawanda kana iwe ukatora Taltz kazhinji.

Ovhadhozi zviratidzo

Zviratidzo zvekuwedzeredza zvinogona kusanganisira mhedzisiro inowanzoitika zvakanyanya kana zvakanyanya kuoma, senge:

  • zvirwere zvepamusoro zvekufema, senge dzihwa
  • kusvotwa
  • fungal hutachiona, senge mutambi wemutsoka
  • kukanganiswa kweakanyanya kukanganiswa
  • chirwere chinoputira chirwere (IBD), chakadai seCrohn's disease kana ulcerative colitis
  • njodzi yakawedzera yehutachiona, senge tibhii (TB)

Zvekuita kana ovhadhozi

Kana iwe uchifunga kuti watora zvakawandisa zvemushonga uyu, fonera chiremba wako. Iwe unogona zvakare kufonera iyo American Association yePoison Control Centres pa800-222-1222 kana kushandisa yavo yepamhepo chishandiso. Asi kana zviratidzo zvako zvakakomba, fonera 911 kana kuenda kukamuri yepedyo yevanokurumidza ipapo.

Taltz kupera, kuchengetedza, uye kurasa

Paunowana Taltz kubva kukhemisi, wemishonga anowedzera zuva rekupera kune zvakanyorwa pabhodhoro. Zuva iri rinowanzo kuve gore rimwe kubva pazuva ravakapa mushonga.

Zuva rekupera rinobatsira kuvimbisa kushanda kwemushonga panguva ino. Chimiro chazvino cheKudya neDrug Administration (FDA) ndechekudzivirira kushandisa akapera mishonga. Kana iwe usina kushandisa mishonga yakapfuura nguva yekupera, bvunza wako wemishonga kana iwe uchiri kukwanisa kuishandisa.

Kuchengetedza

Inguva yakareba sei mushonga unoramba wakanaka unogona zvinoenderana nezvinhu zvakawanda, zvinosanganisira kuti unochengetera mushonga kupi uye kupi.

Taltz majekiseni akazara uye autoinjector matanga anofanirwa kuchengetwa mufiriji pa36 ° F kusvika 46 ° F (2 ° C kusvika 8 ° C). Ita shuwa kuti vasvika pasingasviki vana. Usaomesera Taltz. Uye usashandise mushonga kana wanga wakagwamba nechando.

Mune zvimwe zviitiko, ungangoda kutora Taltz kubva mufiriji usati waishandisa. Semuenzaniso, kana uchienda kwemazuva mashoma uye uchizoda jekiseni panguva iyoyo. Ziva kuti iwe unogona kuchengeta Taltz pane tembiricha yemukati kusvika 86 ° F (30 ° C) kwemazuva mashanu.

Ive neshuwa yekuchengeta iyo sirinji kana autoinjector peni mune yayo yekutanga katoni kuti idzivirire kubva pachiedza. Kana ukasashandisa sirinji kana peni mukati memazuva mashanu, uchafanira kuirasa zvakachengeteka. Iwe haufanire kuisa Taltz kumashure mufiriji kana yangochengetwa mukamuri tembiricha.

Kubvisa

Mushure mekunge mave nekushandisa sirinji yeTaltz yakafetwa kana autoinjector peni, chiise mumudziyo unobvumidzwa neFAFA-unotenderwa wekurasa. Izvi zvinobatsira kudzivirira vamwe, kusanganisira vana nezvipfuwo, kubva pakutora mushonga netsaona. Izvo zvinobatsirawo kuchengetedza mushonga kubva mukukuvadza nharaunda.

Kana iwe usina mudziyo unopinza, unogona kutenga imwe online ku pharmacy yako yemuno.

Unogona kuwana matipi anobatsira pakuraswa kwemishonga pano. Iwe unogona zvakare kubvunza wako wemishonga matipi ekuti ungarase sei mushonga wako.

Ruzivo rwehunyanzvi rweTaltz

Ruzivo runotevera rwunopihwa varapi uye vamwe vashandi vezvehutano.

Zviratidzo

Chikafu neDrug Administration (FDA) yakabvumidza Taltz kurapa:

  • zvine mwero kusvika kune yakaoma plaque psoriasis iyo yakakodzera kune systemic kurapa kana phototherapy; zvekushandisa izvi, mushonga unogona kupihwa vakuru nevana vane makore matanhatu zvichikwira
  • inoshanda psoriatic arthritis muvakuru
  • isiri-radiographic axial spondyloarthritis (nr-axSpA) muvakuru
  • inoshanda ankylosing spondylitis (AS), iyo inonziwo radiographic axial spondyloarthritis (r-axSpA); zvekushandisa izvi, mushonga unogona kupihwa vanhu vakuru

Nzira yekuita

Taltz ine ixekizumab, inova humanized IgG monoclonal antibody. Ixekizumab inosarudza zvinangwa uye inosunga kune interleukin-17A (IL-17A). IL-17A ndeimwe yeanopisa cytokines anozivikanwa kuve anoshanda mukugadzira kupisa uye immune mhinduro dzinokonzera chirwere cheporioriatic uye ankylosing spondylitis. Nekusunga kune IL-17A, ixekizumab inomumisa kubva mukudyidzana neI IL-17A receptor uye nekudaro inodzivirira idzi mhinduro.

Pharmacokinetics uye metabolism

Ixekizumab bioavailability yakatarwa kubva pa60% kusvika pa81% zvichitevera jekiseni repasi peganda muzvidzidzo zvepa psoriasis. Yakakwirira bioavailability yakawanikwa kuburikidza jekiseni muhudyu kana ichienzaniswa nedzimwe jekiseni nzvimbo senge ruoko uye dumbu.

Iyo inoreva hafu-hupenyu hwaive mazuva gumi nematatu muzvidzidzo zvine plaque psoriasis.

Iyo metabolic nzira yekubvisa haina kuzivikanwa, asi inotarisirwa kunge yakafanana neiyo endogenous IgG ine nzira dzinogadzira dzinogadzira madiki peptides uye amino acids.

Contraindications

Taltz inopesana mukati mevanhu vane yakanyanya hypersensitivity reaction, senge anaphylaxis, kune ixekizumab kana avo vanowana.

Kuchengetedza

Iyo Taltz autoinjector uye sirinji yakasarudzwa inofanira kuchengetwa mufiriji pa36 ° F kusvika 46 ° F (2 ° C kusvika 8 ° C).

Usagwamba. Dzivirira kubva pachiedza. Usazunungusa. Taltz inogona kuchengetwa pane tembiricha yemukati inosvika 86 ° F (30 ° C) kwemazuva mashanu. Kamwe ikachengetwa mukamuri tembiricha, haifanire kudzoserwa mufiriji.

Disiki: Medical News Nhasi yaedza nepese painogona napo kuti ive neruzivo rwekuti ruzivo rwese rwuri rwechokwadi, rwakazara, uye rwazvino. Nekudaro, chinyorwa ichi hachifanirwe kushandiswa sekutsiva ruzivo uye hunyanzvi hweane rezinesi rezvehutano. Iwe unofanirwa kugara uchibvunza chiremba wako kana imwe nyanzvi yehutano usati watora chero mushonga. Ruzivo rwezvinodhaka ruri pano runogona kuchinja uye haruna kuitirwa kufukidza ese mashandisirwo, madhairekitori, chenjedzo, kunyeverwa, kudyidzana kwezvinodhaka, allergic reaction, kana mhedzisiro. Kushaikwa kweyambiro kana rumwe ruzivo rwemushonga wakapihwa hakuratidze kuti mushonga kana musanganiswa wezvinodhaka wakachengeteka, unoshanda, kana wakakodzera kuvarwere vese kana kushandiswa kwese chaiko.

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