Antiplatelet zvinodhaka - P2Y12 inhibitors

Maplatelet masero madiki muropa rako ayo anoshandiswa nemuviri wako kuumba kugwamba uye kumira kubuda ropa. Kana iwe uine maplatelet akawandisa kana maplatelet ako akanamatira pamwe zvakanyanya, iwe unowanzo mukana wekugwamba. Kuvharisa uku kunogona kuitika mukati medu tsinga uye kunotungamira kurwisa kwemoyo kana sitiroko.

Antiplatelet zvinodhaka zvinoshanda kuita kuti maplatelet ako asanyanya kunamira uye nekudaro anobatsira kudzivirira kuwanda kweropa kubva mukuumba mune yako arteri.

• Aspirin mushonga unodzivirira mapiritsi unogona kushandiswa.
• P2Y12 receptor blockers iri rimwe boka reantiplatelet zvinodhaka. Iri boka remishonga rinosanganisira: clopidogrel, ticlopidine, ticagrelor, prasugrel, uye cangrelor.

Antiplatelet zvinodhaka zvinogona kushandiswa ku:

• Dzivirira chirwere chemwoyo kana sitiroko kune avo vane PAD.
• Clopidogrel (Plavix, generic) inogona kushandiswa panzvimbo yeaspirin kune vanhu vane kudzikira kwemarironari kana vakaiswa stent.
• Dzimwe nguva 2 antiplatelet madhiragi (imwe yacho ingangoita asipurini) inorayirwa vanhu vane angina isina kugadzikana, acute coronary syndrome (angina isina kugadzikana kana zviratidzo zvekutanga zvekurwadziwa kwemoyo), kana avo vakagamuchira stent panguva yePCI
• Nezve chirwere chemwoyo chekutanga uye chechipiri kudzivirira, asipurini yezuva nezuva ndiyo yekutanga sarudzo yekurapa antiplatelet. Clopidogrel inorayirwa pachinzvimbo cheasipurini kune vanhu avo vari maaspirin allergic kana vasingakwanise kushivirira aspirin.
• Aspirin uye yechipiri antiplatelet zvinodhaka zvinowanzo kurudzirwa kune vanhu vari kuita angioplasty ne kana vasina kunhuwa.
• Kudzivirira kana kubata chirwere chemwoyo.
• Dzivirira sitiroko kana kurwisa kwechischemic kurwisa (TIAs zviratidzo zvekunyevera zvekutanga zvekurohwa. Vanonziwo "mini-stroke".)
• Kudzivirira kugwamba kubva pakuumba mukati stents isa mukati medu tsinga kuti uzarure.
• Acute coronary syndrome.
• Mushure mekupfuura nekuvhiya kumisidzana kunoshandisa chakagadzirwa nemunhu kana cheprosthetic inoitwa pane tsinga pazasi pebvi.

Mutapi wako wezvehutano anosarudza kuti ndeupi wemishonga iyi wakanakira dambudziko rako. Dzimwe nguva, iwe unogona kukumbirwa kutora yakaderera dhiini aspirin pamwe chete neimwe yemishonga iyi.

Zvimwe zvinokanganisa zvemushonga uyu zvinogona kusanganisira:

• Manyoka
• Itching
• Nausea
• Mapundu eganda
• Dumbu kurwadziwa

Usati watanga kutora iyi mishonga, udza mupi wako kana:

• Une matambudziko ekubuda ropa kana maronda emudumbu.
• Iwe uri nepamuviri, uronga kuve nepamuviri, kana uri kuyamwisa.

Kune akatiwandei emimwe mhedzisiro inogona kuitika, zvinoenderana nekuti ndeupi mushonga waunorayirwa. Semuyenzaniso:

• Ticlopidine inogona kutungamira kune yakadzika kwazvo chena masero eropa kana chirwere chemuviri chinoparadza maplatelet.
• Ticagrelor inogona kukonzera zvikamu zvekufema kwekufema.

Mushonga uyu unotorwa sepiritsi. Mupiki wako anogona kuchinja dhizaini yako nguva nenguva.

Tora mushonga uyu nechikafu uye nemvura yakawanda yekudzora mhedzisiro. Ungangoda kumira kurega kutora clopidogrel usati wavhiyiwa kana basa remazino. Usango mira kutora mushonga wako usati watanga kutaura nemupi wako.

Taura nemupi wako usati watora chero eaya madhiragi:

• Heparin nedzimwe ropa dzakapfava, senge warfarin (Coumadin)
• Marwadzo kana mushonga weArthritis (senge diclofenac, etodolac, ibuprofen, indomethacin, Advil, Aleve, Daypro, Dolobid, Feldene, Indocin, Motrin, Orudis, Relafen, kana Voltaren)
• Phenytoin (Dilantin), tamoxifen (Nolvadex, Soltamox), tolbutamide (Orinase), kana torsemide (Demadex)

Usatore mimwe mishonga inogona kunge iine aspirin kana ibuprofen mavari usati wataura nemupi wako. Verenga zvinyorwa pamishonga inotonhora uye yechirwere. Bvunza kuti ndeipi mimwe mishonga yakachengeteka kuti iwe utore maaches nemarwadzo, dzihwa, kana dzihwa.

Kana iwe uine chero rudzi rwemaitiro akarongwa, ungangoda kumisa aya madhiragi mazuva mashanu kusvika manomwe pamberi poruoko. Nekudaro, gara uchitarisa nemupi wako kutanga nezve kana zvakachengeteka kumira.

Udza mupiki wako kana iwe uri nepamuviri kana kuronga kuve nepamuviri, kana kuyamwisa kana kuronga kuyamwisa. Vakadzi mumatanho ekupedzisira epamuviri havafanirwe kutora clopidogrel. Clopidogrel inogona kupfuudzwa kune vacheche kuburikidza nemukaka wemukaka.

Taura nemupi wako kana iwe uine chiropa kana hosha yeitsvo.

Kana iwe ukarasikirwa nedosi:

• Tora iyo nekukurumidza sezvinobvira, kunze kwekunge iri nguva yedosi rako rinotevera.
• Kana iri nguva yeyako dosi inotevera, tora yako yakajairwa huwandu.
• Usatore mapiritsi ekuwedzera kuti uwane muhosi wawakarasikirwa nawo, kunze kwekunge chiremba wako akakuudza kuti uite.

Chengetedza iyi mishonga uye mimwe mishonga munzvimbo inotonhorera uye yakaoma. Zvichengete uko vana vasingakwanise kusvika kwazviri.

Fona kana iwe uine imwe yeiyi mhedzisiro uye haiende:

• Chero zviratidzo zvekubuda ropa zvisina kujairika, senge ropa mumurini kana zvituru, kubuda ropa mumhino, chero kupenga kusingawanzo, kubuda ropa kwakanyanya kubva mukucheka, zvituru zvekumira, kukosora ropa, kunorema kupfuura kugara uchienda kumwedzi kubuda ropa kana kusangana nekutsi kwemukadzi kusingatarisirwe, marutsi anotaridzika senge nzvimbo yekofi
• Dzungu
• Zvakaoma kumedza
• Kuomarara mubhokisi rako kana kurwadziwa muchipfuva
• Kuzvimba kumeso kwako kana maoko
• Itching, mikoko, kana kutetepa kumeso kwako kana maoko
• Kurira kana kunetseka kufema
• Kurwadziwa zvakanyanya mudumbu
• Mapundu eganda

Ropa rakapfava - clopidogrel; Antiplatelet kurapa - clopidogrel; Thienopyridines

• Plaque inovaka mutsinga

Abraham NS, Hlatky MA, Antman EM, uye al. ACCF / ACG / AHA 2010 nyanzvi yekubvumirana gwaro pane inoenderana mashandisirwo eproton pump inhibitors uye thienopyridines: yakatarisana kugadzirisa kweACCF / ACG / AHA 2008 nyanzvi yekubvumirana gwaro rekudzora njodzi dzemudumbu dzeantiplatelet therapy uye NSAID kushandisa: mushumo weiyo American College yeCardiology Foundation Task Force pane Nyanzvi Consensus Zvinyorwa. J Ndiri Coll Cardiol. 2010; 56 (24): 2051-2066. PMID: 21126648 pubmed.ncbi.nlm.nih.gov/21126648/.

Fihn SD, Blankenship JC, Alexander KP, et al. 2014 ACC / AHA / AATS / PCNA / SCAI / STS yakanangana nekudzidziswa kweiyo gwara rekuongororwa uye manejimendi evarwere vane yakatsiga ischemic moyo chirwere: mushumo weAmerican College yeCardiology / American Heart Association Task Force pane Dzidzira Maitiro, uye iyo American Association for Thoracic Kuvhiya, Kudzivirira Cardiovascular Nurses Association, Sosaiti yeCardiovascular Angiography uye Kupindira, uye Sosaiti yeTracic Surgeons. Kutenderera. 2014; 130: 1749-1767. PMID: 25070666 pubmed.ncbi.nlm.nih.gov/25070666/.

Ndarama yeLB. Kudzivirira uye manejimendi yeschemic sitiroko. Mune: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Chirwere Chemwoyo cheBraunwald: A Chinyorwa cheCardiovascular Medicine. 11th ed. Philadelphia, PA: Elsevier; 2019: chits. 65.

Ndira CT, Wann LS, Alpert JS, et al. 2014 AHA / ACC / HRS nhungamiro yevatungamiriri vevarwere vane atrial fibrillation: mushumo weAmerican College yeCardiology / American Heart Association Task Force paMitemo Yekudzidzira uye iyo Mwoyo Rhythm Society. J Ndiri Coll Cardiol. 2014; 64 (21): e1-e76. PMID: 24685669 pubmed.ncbi.nlm.nih.gov/24685669/.

Mauri L, Bhatt DL. Percutaneous coronary kupindira. Mune: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Chirwere Chemwoyo cheBraunwald: A Chinyorwa cheCardiovascular Medicine. 11th ed. Philadelphia, PA: Elsevier; 2019: chitsuwa 62.

Meschia JF, Bushnell C, Boden-Albala B, uye al. Nongedzo dzekudzivirira kwekutanga sitiroko: chirevo chevashandi vezvehutano kubva kuAmerican Heart Association / American Stroke Association. Kurohwa. 2014; 45 (12): 3754-3832. PMID: 25355838 pubmed.ncbi.nlm.nih.gov/25355838/.

Mangwana DA, de Lemos JA. Yakasimba ischemic chirwere chemoyo. Mune: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Chirwere Chemwoyo cheBraunwald: A Chinyorwa cheCardiovascular Medicine. 11th ed. Philadelphia, PA: Elsevier; 2019: chits. 61.

Masimba WJ, Rabinstein AA, Ackerson T, et al. Nongedzo yekutungamira kwekutanga kwevarwere vane acute ischemic sitiroko: 2019 kugadzirisa kune e2018 Guidelines ekutanga manejimendi evarwere vane acute ischemic sitiroko: nhungamiro yevanochengetedza hutano kubva kuAmerican Heart Association / American Stroke Association Kurohwa. 2019; 50 (12): e344-e418. PMID: 31662037 pubmed.ncbi.nlm.nih.gov/31662037/.

• Angina
• Angioplasty uye stent kuiswa - carotid arteri
• Angioplasty uye stent kuiswa - peripheral arteri
• Kuvhiya kweaortic vharuvhu - kushomeka zvishoma
• Kuvhiya kweaortic vharuvhu - yakavhurika
• Maitiro ekubvisa moyo
• Carotid tsinga yekuvhiya - yakavhurika
• Chirwere chisingaperi chinodzivirira pulmonary chirwere (COPD)
• Coronary chirwere chemoyo
• Moyo unopfuura kuvhiya
• Moyo wekupfuura kuvhiya - zvishoma zvinokanganisa
• Kutadza kwemoyo
• Mwoyo pacemaker
• Yakakwira ropa cholesterol cholesterol
• Yakakwira BP - vakuru
• Inodyara cardioverter-defibrillator
• Kuvhiyiwa kweMitral vharuvhu - zvishoma zvinokanganisa
• Mitral valve kuvhiyiwa - kuvhura
• Peripheral tsinga yokunzvenga - gumbo
• Peripheral tsinga chirwere - makumbo

• Angina - kubuda
• Angioplasty uye stent - moyo - kubuda
• Angioplasty uye stent kuiswa - carotid arteri - kubuda
• Angioplasty uye stent kuiswa - peripheral arteri - kubuda
• Aspirin uye chirwere chemwoyo
• Atrial fibrillation - kubuda
• Kuva unoshingaira kana uine chirwere chemwoyo
• Catheterization yemwoyo - kubuda
• Carotid arteri kuvhiya - kubuda
• Kudzora kukwira kweropa rako
• Chirwere cheshuga - kudzivirira chirwere chemwoyo uye sitiroko
• Kurwadziwa kwemoyo - kubuda
• Kuvhiya kwepamoyo - kubuda
• Moyo wekupfuura kuvhiya - kushomeka zvisingaite - kubuda
• Kutadza kwemoyo - kubuda
• Kuvhiya kwevhavha yemoyo - kubuda
• Peripheral tsinga inopfuura - gumbo - kubuda
• Stroke - kubuda

• Ropa Rakaonda