Dubin-Johnson chirwere

Dubin-Johnson syndrome (DJS) chirwere chinopfuura nemumhuri (nhaka). Mune ino mamiriro, iwe unogona kunge uine nyoro jaundice muhupenyu hwese.

DJS chirwere chisingawanzoitika pamagene. Kuti ugare nhaka mamiriro acho, mwana anofanira kuwana kopi yeakaremara gene kubva kuvabereki vese.

Iyo syndrome inopindira nekukwanisa kwemuviri kutamisa bilirubin kuburikidza nechiropa kupinda munyuchi. Kana chiropa nechiropa zvikatyora masero matsvuku eropa, bilirubin inogadzirwa. Bilirubin inowanzo famba ichienda kune iyo bile, iyo inogadzirwa nechiropa. Iyo inozoyerera ichipinda mukati memaburi ducts, yapfuura nduru, uye ichipinda munzira yekugaya.

Kana bilirubin isina kuendeswa zvakanaka mu bile, inovaka muropa. Izvi zvinoita kuti ganda nevachena vemeso vasvike kuita yero. Izvi zvinonzi jaundice. Zvikamu zvakakwirira zvebilirubin zvinogona kukuvadza huropi uye dzimwe nhengo.

Vanhu vane maDJ vane jaundice yeupenyu hwese inogona kuitiswa zvakashata ne:

• Doro
• Mapiritsi ekudzivirira kubata pamuviri
• Zvakatipoteredza zvinhu zvinokanganisa chiropa
• Utachiona
• Kubata pamuviri

Hunyoro jaundice, iyo inogona kunge isingaoneke kusvika pakuyaruka kana kuva munhu mukuru, kazhinji ndiyo chete chiratidzo cheDJS.

Iyi bvunzo inotevera inogona kubatsira kuongorora iyi syndrome:

• Chiropa biopsy
• Chiropa enzyme mazinga (kuongororwa kweropa)
• Serum bilirubin
• Urinary coproporphyrin mazinga, kusanganisira coproporphyrin I nhanho

Hapana kurapwa chaiko kunodiwa.

Maonero acho akanaka kwazvo. DJS kazhinji haina kupfupisa hupenyu hwemunhu.

Matambudziko haana kujairika, asi anogona kusanganisira zvinotevera:

• Marwadzo emudumbu
• Yakanyanya jaundice

Fonera wako mupi wezvehutano kana chero chinotevera chikaitika:

• Jaundice yakaoma
• Jaundice inowedzera kuwedzera nekufamba kwenguva
• Iwe zvakare une kurwadziwa kwepamuviri kana zvimwe zviratidzo (izvo zvinogona kunge zviri chiratidzo chekuti chimwe chirwere chiri kukonzera jaundice)

Kana uine nhoroondo yemhuri yeDJS, kurairwa kwemajini kunogona kubatsira kana ukaronga kuita vana.

• Digestive system nhengo

Korenblat KM, Berk PD. Svika kune murwere ane jaundice kana isina kujairika yechiropa bvunzo. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chitsiko 138.

Lidofsky SD. Jaundice. Muna: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger uye Fordtran's Gastrointestinal uye Chirwere Chiropa. 11th ed. Philadelphia, PA: Elsevier; 2021: chitsiko 21.

Roy-Chowdhury J, Roy-Chowdhury N. Bilirubin metabolism uye kusagadzikana kwayo. Mune: Sanyal AJ, Terrault N, eds. Zakim naBoyer's Hepatology: Chinyorwa cheLiver Disease. 7th ed. Philadelphia, PA: Elsevier; 2018: chitsiko 58.