Glucagonoma

Glucagonoma chinhu chisingawanzoitika bundu reislet maseru epascreas, ayo anotungamira mukuwedzeredza kwehomoni glucagon muropa.

Glucagonoma inowanzo kenza (yakaipa). Gomarara rinowanzopararira nekuwedzera.

Gomarara iri rinokanganisa maseru echisipancreas. Nekuda kweizvozvo, maseru eislet anoburitsa yakawandisa mahormone glucagon.

Chikonzero hachizivikanwe. Majini anoshanda mune dzimwe nguva. Nhoroondo yemhuri yeiyo syndrome yakawanda endocrine neoplasia mhando I (MEN I) chinhu chengozi.

Zviratidzo zveglucagonoma zvinogona kusanganisira chero zvinotevera:

• Kusagadzikana kweglucose (muviri une dambudziko kuputsa shuga)
• Yakakwira ropa shuga (hyperglycemia)
• Manyoka
• Kunyanyisa nyota (nekuda kweshuga yakakwira muropa)
• Kakawanda kuita weti (nekuda kweshuga yeropa)
• Kuwedzera kudya
• Yakaputika muromo uye rurimi
• Nguva yemanheru (husiku) kuita weti
• Kuputika kweganda kumeso, dumbu, magaro, kana tsoka dzinouya dzichienda, uye dzinotenderera
• Kuonda

Muzviitiko zvakawanda, kenza yatopararira kuchiropa kana yaonekwa.

Anopa hutano anoita bvunzo dzepanyama uye obvunza nezve nhoroondo yako yezvokurapa nezviratidzo.

Miedzo inogona kuitwa inosanganisira:

• CT scan yemudumbu
• Glucagon level muropa
• Chikamu cheglucose muropa

Kuvhiya kubvisa bundu kunowanzo kurudzirwa. Bundu harigaro kupindura chemotherapy.

Unogona kudzikisira kushushikana kwehurwere nekujoinha boka rekutsigira gomarara. Kugovana nevamwe vane zvakajairika zviitiko uye matambudziko zvinogona kukubatsira kuti usazonzwa kusurukirwa.

Inenge 60% yemamota aya ane cancer. Zvakajairika kuti gomarara iri ripararire kuchiropa. Chete makumi maviri muzana yevanhu vanogona kurapwa nekuvhiya.

Kana bundu riripo chete mupancreas uye kuvhiyiwa kuti ribvise zvinobudirira, vanhu vane makore mashanu ekupona mwero we 85%.

Kenza inogona kutapukira kuchiropa. Yakakwira shuga yeropa chikamu chinogona kukonzera matambudziko ne metabolism uye kukuvara kwetishu.

Fonera waunopa kana iwe ukaona zviratidzo zveglucagonoma.

VANHU I - glucagonoma

• Endocrine masero

National Cancer Institute webhusaiti. Pancreatic neuroendocrine tumors (islet cell tumors) kurapwa (PDQ) - hutano nyanzvi vhezheni. www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq. Yakagadziridzwa Kukadzi 8, 2018. Yakasvika munaNovember 12, 2018.

Schneider DF, Mazeh H, Lubner SJ, Jaume JC, Chen H. Kanzera yeiyo endocrine system. Mune: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff's Clinical Oncology. 5 ed. Philadelphia, PA: Elsevier Saunders; 2014: chits.

Vella A. Mahormoni emudumbu uye matumbu endocrine tumarara. Mune: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Chinyorwa cheEndocrinology. 13 ed. Philadelphia, PA: Elsevier; 2016: chitsiko 38.