Glomerulonephritis

Glomerulonephritis rudzi rwechirwere cheitsvo umo chikamu cheitsvo dzako chinobatsira kusefa marara uye mvura kubva muropa zvakuvara.

Chikamu chesefa cheitsvo chinonzi glomerulus. Itsvo yega yega ine zviuru zve glomeruli. Iyo glomeruli inobatsira muviri kubvisa zvinhu zvinokuvadza.

Glomerulonephritis inogona kukonzerwa nezvinetso ne immune immune system. Kazhinji, chikonzero chaicho cheichi chiitiko hachizivikanwe.

Kukuvadza kune iyo glomeruli kunokonzera kuti ropa nemapuroteni arasike mumugini.

Mamiriro acho anogona kukura nekukurumidza, uye itsvo inoshanda inorasika mukati memavhiki kana mwedzi. Izvi zvinonzi zvinokurumidza kufambira mberi glomerulonephritis.

Vamwe vanhu vane chisingaperi glomerulonephritis havana nhoroondo yechirwere cheitsvo.

Izvi zvinotevera zvinogona kuwedzera njodzi yako kune ino mamiriro:

• Ropa kana lymphatic system kusagadzikana
• Kuratidzwa kune hydrocarbon solvents
• Nhoroondo yekenza
• Zvirwere zvakadai sehutachiona hwehutachiona, hutachiona, hutachiona hwemwoyo, kana mapundu

Mamiriro ezvinhu mazhinji anokonzera kana kuwedzera njodzi ye glomerulonephritis, inosanganisira:

• Amyloidosis (kusagadzikana uko mapuroteni anonzi amyloid anovaka munhengo uye munyama)
• Kushungurudzika kunokanganisa iyo glomerular yepasi membrane, chikamu cheitsvo icho chinobatsira kusefa marara uye nekuwedzera mvura kubva muropa
• Zvirwere zveropa, zvakadai sevasculitis kana polyarteritis
• Focal sekisheni glomerulosclerosis (kuora kweiyo glomeruli)
• Anti-glomerular basement membrane chirwere (kusagadzikana uko immune system inorwisa iyo glomeruli)
• Analgesic nephropathy syndrome (chirwere cheitsvo nekuda kwekushandisa kwakanyanya kwekurwadziwa kunodzora, kunyanya maNSAID)
• Henoch-Schönlein purpura (chirwere chinosanganisira mavara epepuru paganda, marwadzo akabatana, matambudziko emimba uye glomerulonephritis)
• IgA nephropathy (kusagadzikana umo maantibodies anonzi IgA anovaka muitsvo tishu)
• Lupus nephritis (itsvo kuomarara kwe lupus)
• Membranoproliferative GN (chimiro che glomerulonephritis nekuda kwekusanzwisisika kwekuvaka kwema antibodies muitsvo)

Zviratidzo zvakajairika zve glomerulonephritis ndezvi:

• Ropa mumurini (rima, ruvara-ruvara, kana mutsvuku)
• Foamy weti (nekuda kweprotein yakawandisa mumugini)
• Kuzvimba (edema) yechiso, maziso, makumbo, tsoka, makumbo, kana dumbu

Zviratidzo zvinogona zvakare kusanganisira zvinotevera:

• Marwadzo emudumbu
• Ropa mumarutsi kana zvituru
• Kukosora uye kufema kwekufema
• Manyoka
• Kunyanyisa kuita weti
• Kupindwa nechando
• Kazhinji kurwara kunzwa, kuneta, uye kurasikirwa nechido
• Joint kana tsandanyama aches
• Nemhino

Zviratidzo zvechirwere chetsvo chisingaperi chinogona kukura nekufamba kwenguva.

Husingaperi itsvo kukundikana zviratidzo zvinogona zvishoma nezvishoma kukura.

Nekuti zviratidzo zvinogona kukura zvishoma nezvishoma, hosha yacho inogona kuwanikwa kana iwe uine urinalysis isina kujairika panguva yechiitiko chemuviri kana kuongororwa kweimwe mamiriro.

Zviratidzo zve glomerulonephritis zvinogona kusanganisira:

• Anemia
• Kuwedzera kweropa
• Zviratidzo zvekuderedzwa kweitsvo

Itsvo biopsy inosimbisa kuongororwa.

Gare gare, zviratidzo zvechirwere chetsvo chisingaperi zvinogona kuonekwa, kusanganisira:

• Tsinga kuzvimba (polyneuropathy)
• Zviratidzo zvekuwandisa kwemvura, kusanganisira zvisina kujairika moyo nemapapu kurira
• Kuzvimba (edema)

Kufungidzira bvunzo dzinogona kuitwa dzinosanganisira:

• Abdominal CT scan
• Itsvo Ultrasound
• Chest x-ray
• Intravenous pyelogram (IVP)

Urinalysis uye kumwe kuongorora kweweti kunosanganisira:

• Chibvumirano cheCreatinine
• Kuongorora weti pasi pe microscope
• Weti puroteni yakazara
• Uric acid mune weti
• Weti yevasungwa bvunzo
• Weti creatinine
• Weti mapuroteni
• Weti RBC
• Weti chaiyo giravhiti
• Weti osmolality

Ichi chirwere chinogona kukonzeresa zvisina kujairika mhedzisiro pane inotevera kuongororwa kweropa:

• Albumin
• Antiglomerular yepasi membrane membrane antibody bvunzo
• Antineutrophil cytoplasmic antibodies (ANCAs)
• Antinuclear antibodies
• BUN uye creatinine
• Zadzisa mazinga

Kurapa kunoenderana nechikonzero chechirwere, uye mhando uye kuomarara kwezviratidzo. Kudzora kukwirira kweropa kazhinji chikamu chakakosha pakurapa.

Mishonga inogona kupihwa inosanganisira:

• Ropa kumanikidza zvinodhaka, kazhinji angiotensin-inoshandura enzyme inhibitors uye angiotensin receptor blockers
• Corticosteroids
• Mishonga inodzvinyirira immune system

Maitiro anonzi plasmapheresis dzimwe nguva anogona kushandiswa kune glomerulonephritis inokonzerwa nezvinetso zvemuviri. Chikamu cheropa chine ma antibodies chinobviswa chotsiviwa nemvura inopinza kana plasma yakapihwa (isina ma antibodies). Kubvisa masoja ekudzivirira chirwere kunogona kudzikisa kuzvimba muitsvo dzeitsvo.

Ungangoda kudzikisira kudya kwako kwesodium, zvinwiwa, mapuroteni nezvimwe zvinhu.

Vanhu vane chirwere ichi vanofanirwa kunyatso tariswa zviratidzo zveitsvo kutadza. Dialysis kana itsvo kupinza inogona kupedzisira ichidikanwa.

Iwe unogona kazhinji kudzikisira kushushikana kwehurwere nekujoinha mapoka ekutsigira uko nhengo dzinogovana zvakajairika zviitiko nematambudziko.

Glomerulonephritis inogona kunge iri yenguva pfupi uye ichidzoserwa, kana inogona kuwedzera. Kufambira mberi glomerulonephritis kunogona kutungamira ku:

• Kusingaperi itsvo kutadza
• Yakaderedzwa itsvo kushanda
• End-danho chirwere cheitsvo

Kana iwe uine nephrotic syndrome uye inogona kudzorwa, iwe unogona zvakare kukwanisa kudzora zvimwe zviratidzo. Kana isingakwanise kudzorwa, unogona kukura chirwere chetsvo-yekupedzisira.

Fonera wako mupi wezvehutano kana:

• Iwe une mamiriro anowedzera njodzi yako kune glomerulonephritis
• Unokudziridza zviratidzo zve glomerulonephritis

Mazhinji kesi dze glomerulonephritis haigone kudzivirirwa. Zvimwe zviitiko zvinogona kudzivirirwa nekudzivirira kana kudzikisira kuratidzwa kune organic solvents, mercury, uye nonsteroidal anti-anogumbura zvinodhaka (NSAIDs)

Glomerulonephritis - isingagumi; Chisingaperi nephritis; Glomerular chirwere; Necrotizing glomerulonephritis; Glomerulonephritis - crescentic; Crescentic glomerulonephritis; Inokurumidza kufambira mberi glomerulonephritis

• Itsvo anatomi
• Glomerulus uye nephron

Radhakrishnan J, Appel GB, D'Agati VD. Sekondari glomerular chirwere. Mune: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner uye Rector Iyo Itsvo. 11th ed. Philadelphia, PA: Elsevier; 2020: chits. 32.

Reich HN, Cattran DC. Kurapa kwe glomerulonephritis. Mune: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner uye Rector Iyo Itsvo. 11th ed. Philadelphia, PA: Elsevier; 2020: chits. 33.

Saha MK, Pendergraft WF, Jennette JC, Falk RJ. Chirwere chepakutanga chinoratidzira. Mune: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner uye Rector Iyo Itsvo. 11th ed. Philadelphia, PA: Elsevier; 2020: chits. 31.