Kaposi sarcoma

Kaposi sarcoma (KS) chirwere chegomarara cheiyo inobatanidza nyama.

KS mugumisiro wehutachiona ne gamma herpesvirus inozivikanwa seKaposi sarcoma-inosanganisirwa herpesvirus (KSHV), kana munhu herpesvirus 8 (HHV8). Iyo iri mumhuri imwechete seiyo Epstein-Barr hutachiona, iyo inokonzeresa mononucleosis.

KSHV inoparadzirwa kunyanya kuburikidza nemate. Inogona zvakare kupararira kuburikidza nekubatana pabonde, kuwedzerwa ropa, kana kuisirwa. Mushure mekunge yapinda mumuviri, hutachiona hunogona kukanganisa mhando dzakasiyana dzemasero, kunyanya masero anoteedzera tsinga dzeropa nemidziyo yeremphatic Kufanana neese herpesviruses, KSHV inoramba iri mumuviri wako kwehupenyu hwako hwese. Kana immune system yako ikave isina simba mune ramangwana, hutachiona uhu hungave nemukana wekumutsiridza, zvichikonzera zviratidzo.

Kune mhando ina dzeKS dzinoenderana nemapoka evanhu vane hutachiona:

• Classic KS: Inonyanya kubata varume vakuru veEastern Europe, Middle East, uye Mediterranean dzinza. Chirwere chinowanzokura zvishoma nezvishoma.
• Denda (rine hukama neAIDS) KS: Inoitika kazhinji muvanhu vane hutachiona hweHIV uye vane AIDS.
• Endemic (Africa) KS: Inonyanya kubata vanhu veese mazera mu Africa.
• Immunosuppression-inosanganisirwa, kana kuisirwa-inosanganisirwa, KS: Inoitika kune vanhu vakamboiswa nhengo uye iri mishonga inodzvinyirira immune system yavo.

Iwo mamota (maronda) anowanzoonekwa seyebhuruu-tsvuku kana epepuru mapundu paganda. Ivo vatsvuku-pepuru nekuti vakapfuma mumidziyo yeropa.

Maronda anogona kutanga kuoneka pane chero chikamu chemuviri. Ivo zvakare vanogona kuoneka mukati memuviri. Maronda mukati memuviri anogona kubuda ropa. Maronda mumapapu anogona kukonzera sputum ine ropa kana kufema kwekufema.

Anopa hutano anoita bvunzo dzepanyama, achitarisa pazvironda.

Iyi miedzo inotevera inogona kuitwa kuti uongorore KS:

• Bronchoscopy
• CT scan
• Endoscopy
• Ganda biopsy

Maitiro eKS anorapwa zvinoenderana ne:

• Yakawanda sei immune immune inodzvinyirirwa (immunosuppression)
• Nhamba uye nzvimbo yemamota
• Zviratidzo

Mishonga inosanganisira:

• Antiviral Therapy inopesana neHIV, nekuti hapana chaihwo HHV-8
• Kusanganiswa chemotherapy
• Kusunungura maronda
• Radiation kurapa

Maronda anogona kudzoka mushure mekurapwa.

Kurapa KS hakuiti nani mikana yekurarama kubva kuHIV / AIDS pachayo. Maonero anoenderana nemamiriro emunhu ekudzivirira uye huwandu hwehutachiona hweHIV huri muropa rake (viral load). Kana hutachiona hweHIV hukachengetedzwa nemushonga, maronda anowanzo kudzikira ari ega.

Zvinetso zvinogona kusanganisira:

• Kukosora (pamwe kune ropa) nekufema kwekufema kana chirwere chiri mumapapu
• Kuzvimba kwemakumbo kunogona kurwadza kana kukonzera kutapukira kana chirwere chiri muma lymph node emakumbo

Mamota anogona kudzoka kunyangwe mushure mekurapwa. KS inogona kuuraya munhu ane AIDS.

Chimiro chine hukasha chemugumo KS chinogona kupararira nekukurumidza kumapfupa. Chimwe chimiro chinowanikwa muvana vemuAfrica hachikanganisa ganda. Pane kudaro, inopararira kuburikidza nemamosi uye nhengo dzakakosha, uye inogona kukurumidza kuuraya.

Kuita zvepabonde kwakachengeteka kunogona kudzivirira hutachiona hweHIV. Izvi zvinodzivirira HIV / AIDS nematambudziko ayo, kusanganisira KS.

KS inenge isina kumboitika muvanhu vane HIV / AIDS vane chirwere chinodzorwa zvakanaka.

Kaposi's sarcoma; HIV - Kaposi; AIDS - Kaposi

• Kaposi sarcoma - lesion patsoka
• Kaposi sarcoma kumusana
• Kaposi sarcoma - pedyo-kumusoro
• Kaposi's sarcoma pachidya
• Kaposi sarcoma - perianal
• Kaposi sarcoma netsoka

Kaye KM. Kaposi sarcoma-inosanganisirwa herpesvirus (munhu herpesvirus 8). Mune: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, uye Bennett's Maitiro uye Maitiro Ezvirwere zvinotapukira. 9th ed. Philadelphia, PA: Elsevier; 2020: chitsuwa 140.

Merrick ST, Jones S, Glesby MJ. Zviratidzo zveHIV / AIDS. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chitsama 366.

National Cancer Institute webhusaiti. Kaposi sarcoma kurapwa (PDQ) - hutano nyanzvi vhezheni. www.cancer.gov/types/soft-tissue-sarcoma/hp/kaposi-treatment-pdq. Yakagadziridzwa Chikunguru 27, 2018. Yakasvika muna Kukadzi 18, 2021.