Charcot-Marie-Tooth chirwere

Charcot-Marie-Tooth chirwere iboka rematambudziko akapfuudzwa kuburikidza nemhuri dzinokanganisa tsinga dziri kunze kwehuropi uye musana. Aya anonzi maperiperi tsinga.

Charcot-Marie-Tooth ndechimwe chezvinetso zvakajairika zvine chekuita nehutano zvakapfuudzwa kuburikidza nemhuri (nhaka). Shanduko kune angangoita makumi mana majini anokonzera akasiyana mafomu echirwere ichi.

Chirwere ichi chinotungamira mukukuvara kana kuparadzwa kune iyo yekufukidza (myelin sheath) kutenderedza nerve fibers.

Tsinga dzinokurudzira kufamba (dzinonzi mota tsinga) dzinonyanya kukanganiswa. Mitsipa mumakumbo inobatwa kutanga uye zvakanyanya.

Zviratidzo zvinowanzo kutanga pakati pehucheche uye kutanga kukura. Zvinogona kusanganisira:

• Kutsika kwetsoka (yakakwira kwazvo arch kune tsoka)
• Rutsoka rutsoka (kutadza kubata tsoka yakatwasuka)
• Kurasikirwa kwemhasuru yepazasi yegumbo, iyo inotungamira kune mhuru dzakaonda
• Chiveve mutsoka kana gumbo
• "Kurova" gait (tsoka dzakarova pasi zvine simba kana uchifamba)
• Kushaya simba kwehudyu, makumbo, kana tsoka

Gare gare, zviratidzo zvakafanana zvinogona kuoneka mumaoko nemaoko. Izvi zvinogona kusanganisira claw-senge ruoko.

Kuongorora kwepanyama kunogona kuratidza:

• Zvakaoma kusimudza tsoka uye kuita zvigunwe-kunze kufamba (tsoka kudonha)
• Kushaikwa kwekutambanudza mafungiro mumakumbo
• Kurasikirwa kwemhasuru kudzora uye atrophy (kudzikira kwemhasuru) mutsoka kana gumbo
• Makobvu etsinga tsinga pasi peganda remakumbo

Tsinga conduction bvunzo dzinowanzoitwa kuti vaone akasiyana mafomu echirwere. A nerve biopsy inogona kusimbisa kuongororwa.

Kuongorora genetic kunowanikwawo kune akawanda mafomu echirwere.

Iko hakuna mushonga unozivikanwa. Kuvhiya kweOrthopedic kana michina (senge brace kana shangu dzemazino) zvinogona kuita kuti zvive nyore kufamba.

Kurapa kwepanyama uye kwekuita basa kunogona kubatsira kuchengetedza simba remhasuru uye kugadzirisa kushanda kwakazvimirira.

Charcot-Marie-Tooth chirwere chinowedzera kuwedzera. Dzimwe nhengo dzomuviri dzinogona kuita chiveve, uye kurwadziwa kunogona kutangira pane zvinyoro kusvika kune zvakanyanya. Pakupedzisira chirwere chinogona kukonzera kuremara.

Zvinetso zvinogona kusanganisira:

• Kufambira mberi kusakwanisa kufamba
• Kufambira mberi kushaya simba
• Kukuvadza kunzvimbo dzomuviri dzakadzikira kunzwa

Fonera wako mupi wezvehutano kana paine kuenderera kushaya simba kana kudzikira kwekunzwa mumakumbo kana makumbo.

Genetic kuraira uye kuyedzwa zvinokurudzirwa kana paine yakasimba mhuri nhoroondo yechirwere.

Inofambira mberi neuropathic (peroneal) tsandanyama atrophy; Nhaka inokanganisa kusagadzikana kwetsinga; Neuropathy - peroneal (nhaka); Heredhi mota uye yekunzwa neuropathy

• Central nervous system uye yekumusoro tsinga system

Katirji B. Kukanganisika kwemitsipa yekunze. Mune: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology muClinical Dzidzira. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 107.

Sarnat HB. Nhaka inofambisa mota-sensory neuropathies. Mune: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chitsamba 631.