Gomarara reOvarian

Gomarara reOvarian igomarara rinotanga mumazai. Mazai acho inhengo dzekubereka dzechikadzi dzinoburitsa mazai.

Kenza yeOvarian ndiyo yechishanu kenza yakajairika pakati pevakadzi. Inokonzera kufa kwakawanda kupfuura chero imwe mhando yekenza yemukadzi yekubereka.

Chikonzero checancer ovarian hachizivikanwe.

Njodzi dzekuvandudza kenza yeovari dzinosanganisira chero cheanotevera:

• Vana vashoma vane mukadzi uye mumashure muhupenyu waanosununguka, inowedzera mukana wecancer ovarian.
• Vakadzi vane kenza yemazamu kana vane nhoroondo yemhuri yekenza yemazamu kana ovari vane njodzi yakawedzera yekenza yeovarian (nekuda kwekukanganisa mumajini akaita se BRCA1 kana BRCA2).
• Vakadzi vanotora isrogen kutsiva chete (kwete neprogesterone) kwemakore mashanu kana kupfuura vanogona kuve nenjodzi yakakwira yegomarara reovari. Kubata mapiritsi, zvisinei, kunoderedza njodzi yekenza yeovarian.
• Mushonga wekubereka pamwe haawedzere njodzi yekenza yemazai.
• Vakadzi vechikuru vari panjodzi yepamusoro yekuva negomarara rezai. Vazhinji vanofa kubva kune ovarian cancer vanoitika kune vakadzi vane makore makumi mashanu nemashanu zvichikwira.

Ovarian kenza zviratidzo zvinowanzo kuve zvisina kujeka. Vakadzi navanachiremba vavo vanowanzo pomera zviratidzo kune mamwe, akajairika mamiriro. Nenguva iyo kenza ichionekwa, bundu racho rinowanzopararira kupfuura mazai.

Ona chiremba wako kana iwe uine zvinotevera zviratidzo zuva nezuva kweanopfuura mavhiki mashoma:

• Kuvhara kana kuzvimba mudumbu nzvimbo
• Kunetseka kudya kana kunzwa kuzara nekukurumidza (kutanga kuguta)
• Pelvic kana kurwadziwa pasi mudumbu (nzvimbo inogona kunzwa "inorema")
• Kutambudzika shure
• Kuzvimba lymph node mune kugomera

Zvimwe zviratidzo zvinogona kuitika:

• Bvudzi rakanyanya kukura iro rakakora uye rakasviba
• Kamwe kamwe kukurudzira kuita weti
• Kutoda kuita weti kakawanda kupfuura zvakajairwa (kuwedzerwa urinary frequency kana kukurumidza)
• Kuzvimbirwa

Bvunzo dzemumuviri dzinowanzo kuve dzakajairika. Nekenza yepamusoro yeovarian, chiremba anogona kuwana dumbu rakazvimba kazhinji nekuda kwekuunganidzwa kwemvura (ascites).

Kuongororwa kwepamuviri kunogona kuratidza ovhari kana mudumbu uremu.

Iyo CA-125 bvunzo yeropa haina kutariswa seyakanaka yekuongorora bvunzo yekenza yeovari. Asi, zvinogona kuitwa kana mukadzi aine:

• Zviratidzo zvecancer ovarian
• Yatove yakawanikwa iine ovarian cancer kuti uone kuti kurapa kuri kushanda sei

Mimwe bvunzo inogona kuitwa inosanganisira:

• Yakazara kuverenga kweropa uye kemisitiri yeropa
• Kubata kwepamuviri (serum HCG)
• CT kana MRI yepelvis kana dumbu
• Ultrasound yemapapiro

Kuvhiya, senge laparoscopy kana kuongorora laparotomy, kunowanzoitwa kuwana chikonzero chezviratidzo. Bhiopsy ichaitwa kubatsira kubatsira kuongororwa.

Hapana rabhoramu kana bvunzo yekufungidzira yakamboratidzwa kuti inokwanisa kubudirira kuongorora kana kuongorora chirwere checancer muchikamu chayo chekutanga, saka hapana bvunzo dzekuyera dzakatarwa dzinokurudzirwa panguva ino.

Kuvhiya kunoshandiswa kurapa ese matanho eiyo ovari kenza. Kwematanho ekutanga, kuvhiyiwa kunogona kunge kuri iko chete kurapwa kunodiwa. Kuvhiya kunogona kusanganisira kubvisa ese maovari uye fallopian machubhu, chibereko, kana zvimwe zvivakwa mudumbu kana chiuno.

• Semuenzaniso zvinowanzoonekwa nzvimbo kuti uone kana gomarara rapararira (staging)
• Bvisa chero nzvimbo dzemota dzakapararira (debulking)

Chemotherapy inoshandiswa mushure mekuvhiyiwa kurapa chero gomarara rinosara. Chemotherapy inogona zvakare kushandiswa kana gomarara rikadzoka (richidzokazve). Chemotherapy inowanzo kupihwa intravenously (kuburikidza ne IV). Inogona zvakare kujowa yakananga mukati medumbu mhango (intraperitoneal, kana IP).

Radiation kurapwa haiwanzo kushandiswa kurapa ovari cancer.

Mushure mekuvhiyiwa uye chemotherapy, tevera rairo nezvekuti kangani kaunofanirwa kuona chiremba wako uye bvunzo dzaunofanirwa kuve nadzo.

Unogona kudzikisira kushushikana kwehurwere nekujoinha boka rekutsigira gomarara. Kugovana nevamwe vane zvakajairika zviitiko uye matambudziko zvinogona kukubatsira kuti usazonzwa kusurukirwa.

Kenza yeOvarian haiwanzo kuongororwa mumatanho ayo ekutanga. Inowanzo kuve yakakwira zvakanyanya nenguva yekuongororwa inoitwa:

• Inenge hafu yevakadzi vanorarama makore anopfuura mashanu mushure mekuongororwa
• Kana kuongororwa kukaitwa pakutanga kwechirwere uye kurapwa kuchigamuchirwa kenza isati yapararira kunze kweiyo ovari, makore mashanu ekupona mwero wakakwira.

Bata wako mupi wezvehutano kana iwe uri mukadzi makore makumi mana kana kupfuura asina kunge achangobva kuongororwa pelvic. Kazhinji bvunzo dzechiuno dzinokurudzirwa kune vese vakadzi makore makumi maviri kana kupfuura.

Sheedza musangano pamwe nemupi wako kana iwe uine zviratidzo zvecancer ovarian.

Iko hakuna kurudziro yakajairwa yekuongorora vakadzi vasina zviratidzo (asymptomatic) yekenza yeovari. Pelvic ultrasound kana kuongororwa kweropa, senge CA-125, hazvina kuwanikwa zvichishanda uye hazvikurudzirwe.

Kuongorora kweGenetic kweBrCA1 kana BRCA2, kana mamwe majeni ane chekuita nekenza, anogona kukurudzirwa kune vakadzi vari panjodzi huru yekenza yeovarian. Ava ndivo vakadzi vane yavo kana yemhuri nhoroondo yekenza yemazamu kana ovari.

Kubvisa maovari uye fallopian machubhu uye pamwe chibereko mune vakadzi vane chiratidzo chakachinja muBRCA1 kana BRCA2 geni kunogona kudzora njodzi yekuva nekenza yemazai. Asi, ovarian cancer inogona kuramba ichikura mune dzimwe nzvimbo dzepelvis.

Gomarara - mazai

• Abdominal radiation - kubuda
• Chemotherapy - chii chekubvunza chiremba wako
• Pelvic radiation - kubuda

• Mukadzi wekubereka anatomy
• Ascites nekenza yemazai - CT scan
• Kenza yePeritoneal uye ovari, CT scan
• Ovarian kenza njodzi
• Ovarian kukura kunetseka
• Uterus
• Gomarara reOvarian
• Ovarian kenza metastasis

Coleman RL, Liu J, Matsuo K, Thaker PH, Westin SN, Sood AK. Carcinoma yemazai uye fallopian machubhu. Mune: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020: chits. 86.

Coleman RL, Ramirez PT, Gershenson DM. Neoplastic zvirwere zveovary: kuongorora, benign uye yakaipa epithelial uye hutachiona maseru mapundu, bonde-tambo stromal tumors. Mune: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Yakakwana Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017: chits. 33.

National Cancer Institute webhusaiti. Kuchinja kwe BRCA: njodzi yekenza uye kuongororwa kwemajini. www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet. Yakagadziridzwa Mbudzi 19, 2020. Yakasvika muna Ndira 31, 2021.