Hepatocerebral kudzikira

Hepatocerebral degeneration chirwere chehuropi chinoitika kune vanhu vane kukuvara kwechiropa.

Aya mamiriro anogona kuitika mune chero mamiriro eakawanikwa chiropa kutadza, kusanganisira zvakanyanya hepatitis.

Kukuvara kwechiropa kunogona kutungamira kune iyo yakawedzera ammonia uye zvimwe zvinhu zvine chepfu mumuviri. Izvi zvinoitika kana chiropa chisingashande mushe. Izvo hazviputsi uye kubvisa aya makemikari. Zvinhu zvine chepfu zvinogona kukuvadza hura hwehuropi.

Dzakananga nzvimbo dzehuropi, senge basal ganglia, ari mukana wekukuvara kubva kuchiropa kutadza. Iyo basal ganglia inobatsira kudzora kufamba. Aya mamiriro i "asiri-Wilsonian" mhando. Izvi zvinoreva kuti kukuvara kwechiropa hakukonzerwe nemhangura inoiswa muchiropa. Ichi chinhu chakakosha chechirwere cheWilson.

Zviratidzo zvinogona kusanganisira:

• Kunetsa kufamba
• Kukanganisika kwehungwaru basa
• Jaundice
• Tsvina yemhasuru (myoclonus)
• Rigidity
• Kuzunza maoko, musoro (kudedera)
• Kugwinha
• Kusadzora kufamba kwemuviri (chorea)
• Kufamba usina kugadzikana (ataxia)

Zviratidzo zvinosanganisira:

• Coma
• Fluid mudumbu inokonzeresa kuzvimba (ascites)
• Kubuda ropa mudumbu kubva mutsinga dzakawedzera mupombi yezvikafu (esophageal varices)

A nervous system (neurological) bvunzo inogona kuratidza zviratidzo zve:

• Dementia
• Kufambisa kwekuzvipira
• Kufamba kusagadzikana

Rabhoritari bvunzo dzinogona kuratidza yakakwira ammonia mwero muropa uye isina kujairika chiropa basa.

Mimwe bvunzo inogona kusanganisira:

• MRI yemusoro
• EEG (inogona kuratidza kudzikira kwakawanda kwemafungu ehuropi)
• CT scan yemusoro

Kurapa kunobatsira kudzikisa makemikari ane chepfu anovaka kubva pakutadza kwechiropa. Inogona kusanganisira mishonga inorwisa mabhakitiriya kana mushonga wakadai seLaculose, iyo inoderedza mwero weammonia muropa.

Mushonga unonzi branched-chain amino acid therapy inogona zvakare:

• Kuvandudza zviratidzo
• Dzorera kukuvara kwehuropi

Iko hakuna chaiwo marapirwo eiyo neurologic syndrome, nekuti inokonzereswa nekuchinjika kwechironda kukuvara. Kuiswa kwechiropa kunogona kuporesa chirwere chechiropa. Nekudaro, kuvhiya uku hakugone kudzoreredza zviratidzo zvekukuvara kwehuropi.

Iyi inguva refu (isingagumi) mamiriro ayo anogona kutungamira kune isingachinjiki tsinga system (neurological) zviratidzo.

Munhu wacho anogona kuramba achingowedzera uye achifa asina kuisirwa chiropa. Kana kuiswa kuchinge kwaitwa kare, iyo neurological syndrome inogona kudzoserwa.

Matambudziko anosanganisira:

• Hepatic coma
• Kukuvadza kwakakomba kwehuropi

Fonera wako mupi wehutano kana iwe uine chero zviratidzo zvechiropa chirwere.

Izvo hazvigoneke kudzivirira ese mafomu echiropa chirwere. Nekudaro, chidhakwa uye hutachiona hepatitis inogona kudzivirirwa.

Kuti uderedze njodzi yako yekudhakwa kana hutachiona hepatitis:

• Dzivisa maitiro ane njodzi, senge IV kushandisa zvinodhaka kana bonde risina dziviriro.
• Usanwa, kana kunwa chete zvine mwero.

Chisingaperi chinowanikwa (Isiri-Wilsonian) hepatocerebral degeneration; Hepatic encephalopathy; Portosystemic encephalopathy

• Chiropa anatomy

Garcia-Tsao G. Cirrhosis uye sequelae yayo. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 153.

Haq IU, Tate JA, Siddiqui MS, Okun MS. Kliniki yekutarisa kwekufamba kwekusagadzikana.Mune: Winn HR, ed. Youmans uye Winn Neurological Kuvhiya. 7th ed. Philadelphia, PA: Elsevier; 2017: chap 84.