Zadzisa chikamu 3 (C3)

Kuteedzera C3 kuongororwa kweropa kunoyera chiitiko cheimwe puroteni.

Iyi protein chikamu cheyunisheni system. Iyo yekuwedzera system iboka remapuroteni anoda kusvika makumi matanhatu ari muplasma yeropa kana pamusoro pemamwe maseru. Mapuroteni anoshanda nema immune system ako uye anoita basa rekuchengetedza muviri kubva kuzvirwere, uye kubvisa maseru akafa nezvimwe zvekunze. Kazhinji, vanhu vanogona kugara nhaka kushomeka kwevamwe vanozadzisa mapuroteni. Vanhu ava vanowanzo tenderwa nezvimwe hutachiona kana autoimmune kusagadzikana.

Iko kune mapfumbamwe makuru ekuwedzera mapuroteni. Ivo vakanzi C1 kuburikidza neC9. Ichi chinyorwa chinotsanangura muyedzo unoyera C3.

Ropa rinotorwa kubva mutsinga. Kazhinji kazhinji, tsinga kubva mukati megokora kana kuseri kweruoko inoshandiswa.

Maitiro acho anotevera:

• Iyo saiti inocheneswa neantiseptic.
• Anopa hutano anomonera bhandi rakasunga paruoko rwekumusoro kuisa kumanikidza kunzvimbo uye kuita kuti tsinga izate neropa.
• Mupi anopa zvinyoro nyoro tsono mukati mutsinga.
• Ropa rinoungana mumudziyo usingavharike mweya kana chubhu yakasungirirwa mutsono. Iyo yakasununguka bhandi inobviswa kubva paruoko rwako.
• Ropa parangounganidzwa, tsono inobviswa. Nzvimbo yekubaya yakavharwa kumisa chero kubuda ropa.

Mune vacheche kana vana vadiki, chishandiso chakapinza chinonzi lancet inogona kushandiswa kubaya ganda uye kuita kubuda ropa.Ropa rinoungana mutubhu tudiki girazi kanonzi pipette, kana panotsvedza kana bvunzo. Bhandeji rinogona kuiswa pamusoro penharaunda kana paine kubuda ropa.

Iko hakuna gadziriro yakakosha inodiwa.

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanogona kungonzwa kubaya kana kuruma. Mushure meizvozvo, panogona kunge paine kurovera.

C3 neC4 ndizvo zvinowanzo kuyerwa zvinowedzeredza zvinhu.

Chiyero chekuwedzera chinogona kushandiswa kuongorora vanhu vane autoimmune kusagadzikana. Izvo zvinoitwa kuti uone kana kurapwa kwemamiriro avo kuri kushanda. Kana iyo yekuwedzera system ikashandurwa panguva yekuzvimba, iwo mazinga ekutsigira mapuroteni anogona kudzikira. Semuenzaniso, vanhu vane lupus erythematosus inoshanda vanogona kunge vane yakaderera-kupfuura-yakajairwa mazinga eanobatsira mapuroteni C3 neC4.

Kuteedzera zviitiko zvinosiyana mumuviri wese. Semuenzaniso, mune vanhu vane rheumatoid arthritis, basa rekuwedzera muropa rinogona kunge rakajairika kana rakakwira-kupfuura-rinowanzoitika, asi rakadzika kwazvo-kupfuura-rinowanzoitika mujoin fluid.

Muedzo unogona zvakare kuitwa kune anotevera mamiriro:

• Fungal zvirwere
• Gram isina septicemia
• Utachiona hwehutachiona, hwakadai semarariya
• Paroxysmal husiku hemoglobinuria (PNH)
• Shock

Iyo yakajairwa renji ndeye 88 kusvika ku 201 mamirigiramu padhisita (mg / dL) (0.88 kusvika 2.01 g / L).

Ongorora: zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pema laboratories akasiyana. Taura nemupi wako nezve zvinorehwa nemimwe miedzo yako.

Iyi mienzaniso iripamusoro inoratidza zviyero zvakajairika zvemhedzisiro yeiyi bvunzo. Mamwe marabhoritari anoshandisa zviyero zvakasiyana kana anogona kuyedza mienzaniso dzakasiyana.

Kuwedzera kwekuwedzera chiitiko kunoonekwa mu:

• Gomarara
• Ulcerative colitis

Kuderera kwekuwedzera chiitiko kunoonekwa mu:

• Hutachiona hutachiona (kunyanya Neisseria)
• Cirrhosis
• Glomerulonephritis
• Hepatitis
• Nhaka angioedema
• Itsvo kuisazve kurambwa
• Lupus nephritis
• Kushaya zvokudya zvinovaka muviri
• Systemic lupus erythematosus
• Kazhinji kugarwa kunowedzera kukwana
  
  

Njodzi dzakabatana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

• Kuwedzera kubuda ropa
• Kufenda kana kunzwa kushaya musoro
• Hematoma (ropa rinoungana pasi peganda)
• Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

Iyo inozadzisa iyo Cascade ndeye akateedzana maitiro anoitika muropa. Iyo Cascade inomutsa iyo yekuwedzera mapuroteni. Mhedzisiro yacho yuniti yekurwisa inogadzira maburi mu membrane yebhakitiriya, ichivauraya. C3 inonamira kubhakitiriya uye inoiuraya yakananga.

C3

• Kuongorora ropa

Chernecky CC, Berger BJ. C3 inoenderana (beta-1c-globulin) - serum. Mune: Chernecky CC, Berger BJ, eds. Rabhoritari Kuyedza uye Maitiro Ekuongorora. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 267-268.

Holers VM. Komberedza uye ayo anogamuchira: hutsva hutsva muzvirwere zvevanhu. Annu Rev Immunol. 2014; 32: 433-459. PMID: 24499275 www.ncbi.nlm.nih.gov/pubmed/24499275.

Massey HD, McPherson RA, Huber SA, Jenny NS. Murevereri wekuzvimba: kuzadzisa. Mune: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis uye Management nemaLabhoritari Maitiro. 23rd ed. St Louis, MO: Elsevier; 2017: chits. 47.

Merle NS, Chechi SE, Fremeaux-Bacchi V, Roumenina LT. Komberedza sisitimu chikamu I - mamorekuru maitiro ekumisikidza uye mutemo. Pamberi Immunol. 2015; 6: 262. PMID: 26082779 www.ncbi.nlm.nih.gov/pubmed/26082779.

Merle NS, Noe R, Halbwachs-Mecarelli L, Fremeaux-Bacchi V, Roumenina LT. Komberedza sisitimu chikamu II: basa rekuzvidzivirira. Pamberi Immunol. 2015; 6: 257. PMID: 26074922 www.ncbi.nlm.nih.gov/pubmed/26074922.

Morgan BP, Harris CL. Kwiridzira, chinangwa chekurapa muzvirwere zvinoputira uye zvinogumbura. Nat Rev Zvinodhaka Discov. 2015; 14 (12): 857-877. PMID: 26493766 www.ncbi.nlm.nih.gov/pubmed/26493766.