Munyori: Joan Hall
Zuva Rekusika: 26 Kukadzi 2021
Gadziridza Zuva: 22 Mbudzi 2024
Anonim
Electrophoresis, Immunoelectrophoresis and Immunofixation
Vhidhiyo: Electrophoresis, Immunoelectrophoresis and Immunofixation

Iyo serum globulin electrophoresis bvunzo inoyera iwo mazinga emapuroteni anonzi globulins muchikamu chemvura cheropa. Urume uhwu hunonzi serum.

Muenzaniso weropa unodiwa.

Mubazi, nyanzvi inoisa muyero weropa papepa rakakosha uye woisa magetsi. Mapuroteni anofamba papepa uye ogadzira mabhendi anoratidza huwandu hwepuroteni yega yega.

Tevedza rairo yekuti unofanirwa kutsanya usati waedzwa.

Mimwe mishonga inogona kukanganisa mhedzisiro yeiyi bvunzo. Anokuchengetedza hutano anokuudza kana uchifanira kurega kutora chero mishonga. Usamise chero mushonga usati wataura nemupi wako.

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanongonzwa kubaya kana kubaya. Mushure meizvozvo, panogona kuve nekurohwa kana kupwanya zvishoma. Izvi zvinokurumidza kuenda.

Muedzo uyu unoitwa kutarisa mapuroteni eglobulin muropa. Kuziva mhando dzemaglobulin kunogona kubatsira kuongorora mamwe matambudziko ekurapa.


Globulins akapatsanurwa kuita mapoka matatu: alpha, beta, uye gamma globulins. Gamma globulins anosanganisira akasiyana siyana maantibhakitiriya akadai ma immunoglobulins (Ig) M, G, na A.

Zvimwe zvirwere zvinosangana nekugadzira akawanda maunoglobulin. Semuenzaniso, Waldenstrom macroglobulinemia ikenza yemamwe masero eropa machena. Iyo inosanganisirwa nekuburitsa yakawandisa maImM antibodies.

Akajairika kukosha maseru ndeaya:

  • Serum globulin: 2.0 kusvika 3.5 gramu pa deciliter (g / dL) kana 20 kusvika 35 gramu pa litre (g / L)
  • IgM chinhu: 75 kusvika 300 milligrams pa deciliter (mg / dL) kana mazana matatu kusvika mazana matatu kusvika kumamirigiramu matatu pa litre (mg / L)
  • IgG chinhu: 650 kusvika 1,850 mg / dL kana 6.5 kusvika 18.50 g / L.
  • IgA chinhu: 90 kusvika 350 mg / dL kana 900 kusvika 3,500 mg / L

Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Mamwe marabhu anoshandisa zviyero zvakasiyana kana kuyedza akasiyana sampuli. Taura nemupi wako nezve zvinorehwa nemimwe miedzo yako.

Kuwedzera kwe gamma globulin mapuroteni anogona kuratidza:


  • Hutachiona hutachiona
  • Ropa uye mapfupa emukenza anosanganisira akawanda myeloma, uye mamwe lymphomas uye leukemias
  • Dambudziko rekushomeka kwe immune
  • Yenguva refu (isingagumi) chirwere chinoputika (somuenzaniso, rheumatoid arthritis uye systemic lupus erythematosus)
  • Waldenström macroglobulinemia

Pane njodzi shoma inosanganisirwa nekutorwa kweropa rako. Tsinga uye tsinga zvinosiyana muhukuru kubva kumunhu kuenda kune mumwe, uye kubva kune rimwe divi remuviri kuenda kune rimwe. Kutora ropa kubva kune vamwe vanhu kunogona kunge kwakaoma kupfuura kubva kune vamwe.

Dzimwe njodzi dzinosangana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

  • Kuwedzera kubuda ropa
  • Kufenda kana kunzwa kushaya musoro
  • Akawanda punctures ekutsvaga mutsinga
  • Hematoma (kuwanda kweropa pasi peganda)
  • Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

Kuwanda kwema immunoglobulins

  • Kuongorora ropa

Chernecky CC, Berger BJ. Immunoelectrophoresis - serum uye weti. Mune: Chernecky CC, Berger BJ, eds. Rabhoritari Kuyedza uye Maitiro Ekuongorora. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 667-692.


Dominiczak MH, Fraser WD. Ropa uye mapuroteni eplasma. Mune: Baynes JW, Dominiczak MH, eds. Chiremba Biochemistry. 5 ed. Philadelphia, PA: Elsevier; 2019: chitsuwa 40.

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