Febrile neutropenia: chii zvazviri, zvinokonzera uye kurapwa

Zvemukati

• Zvinokonzera febrile neutropenia
• Kwakadii kurapwa

Febrile neutropenia inogona kutsanangurwa sekuderera kwehuwandu hweeutrophil, ichionekwa mukuyerwa kweropa isingasviki 500 / µL, inosanganiswa nefivhiri kumusoro kana yakaenzana ne 38ºC kweawa rimwe. Aya mamiriro anowanzoitika mune varwere vegomarara mushure memakemikari uye anogona kutungamira kumhedzisiro uye kunetsekana mukurapa kana ikasarapwa nekukasira.

Neutrophils ndiwo masero eropa akakosha ekudzivirira uye kurwisa hutachiona, iyo yakajairika kukosha kuri kutariswa pakati pe1600 ne8000 / µL, iyo inogona kusiyana zvichienderana neirabhoritari. Kana huwandu hwema neutrophils hwakaenzana kana kupfuura 500 / µL, neutropenia yakaoma inofungidzirwa, kuitira kuti munhu abate chirwere chinotapukirwa noutachiona hunogara mumuviri.

Zvinokonzera febrile neutropenia

Febrile neutropenia inowanzo gomarara mune varwere vegomarara vari kurapwa chemotherapy, chiri chimwe chezvikonzero zvikuru zvekufa kwevarwere ava, sezvo kuderera kwenyutrophils kunowedzera njodzi yemunhu yekuve nezvirwere zvakakomba.

Mukuwedzera kune chemotherapy, febrile neutropenia inogona kuitika semhedzisiro yezvirwere zvisingaperi zvinokonzerwa nefungus, mabhakitiriya uye hutachiona, kunyanya Epstein-Barr hutachiona uye hepatitis. Dzidza nezve zvimwe zvinokonzeresa neutropenia.

Kwakadii kurapwa

Kurapa kwe febrile neutropenia kunosiyana zvichienderana nekuomarara. Varwere vakaonekwa sevane febrile neutropenia yakaoma, umo huwandu hwenyutrophili husingasviki kana hwakaenzana ne200 / µL, vanowanzo kurapwa nekushandisa mishonga inorwisa mabhakitiriya yekirasi ye beta-lactams, yechina chizvarwa cephalosporins kana carbapenems. Pamusoro pezvo, kana ari murwere asina kugadzikana pakiriniki kana anofungidzirwa kuti ane hutachiona husingaurayiwe, panogona kukurudzirwa kushandisa mumwe mushonga unorwisa utachiona.

Mune zviitiko zvine njodzi shoma febrile neutropenia, murwere anowanzo kuongororwa, uye huwandu hweropa hwakakwana hunofanirwa kuitwa nguva nenguva kuti uone huwandu hweeutrophils. Uye zvakare, kana fungal kana hutachiona hutachiona hwasimbiswa, kushandiswa kwemishonga inorwisa mabhakitiriya, ingave inorwisa mabhakitiriya kana antifungal, inogona kukurudzirwa nachiremba zvichienderana nemumiririri anoona nezve hutachiona.

Kana febrile neutropenia ikaitika mushure memakemikari, zvinokurudzirwa kuti mushonga wekurwisa mabhakitiriya utange nekukurumidza sezvinobvira mukati meawa rimwe mushure mekutarisa fever.