Kukanganiswa / kutonhora agglutinins

Agglutinins masoja ekudzivirira anoita kuti masero matsvuku eropa abatane pamwe chete.

• Cold agglutinins inoshanda panotonhora kutonhora.
• Febrile (inodziya) agglutinins inoshanda pane yakajairwa tembiricha yemuviri.

Ichi chinyorwa chinotsanangura kuongororwa kweropa kunoshandiswa kuyera mwero wema antibodies muropa.

Muenzaniso weropa unodiwa.

Iko hakuna kugadzirira kwakakosha.

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanongonzwa kubaya kana kubaya. Mushure meizvozvo, panogona kuve nekurova uko tsono yakaiswa.

Bvunzo iyi inoitwa kuongorora zvimwe hutachiona nekuwana chinokonzera hemolytic anemia (rudzi rweanemia runoitika kana masero matsvuku eropa aparadzwa). Kuziva kana paine kudziya kana kutonhora agglutinins kunogona kubatsira kutsanangura kuti nei hemolytic anemia iri kuitika uye yakananga kurapwa.

Mhedzisiro mhedzisiro ndeiyi:

• Warm agglutinins: hapana kuunganidzwa mune titers pa kana pazasi pe1: 80
• Cold agglutinins: hapana kuumbana mumatitari ari kana pazasi pe1: 16

Iyi mienzaniso iripamusoro zviyero zvakajairika zvemhedzisiro yeiyi bvunzo. Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Mamwe marabhu anoshandisa zviyero zvakasiyana kana kuyedza akasiyana sampuli. Taura nachiremba wako nezve zvinorehwa nemimwe miedzo yako.

Mhedzisiro isingawanzo (yakanaka) zvinoreva kuti paive nema agglutinin muropa rako.

Warm agglutinins anogona kuitika ne:

• Zvirwere, zvinosanganisira brucellosis, rickettsial chirwere, salmonella chirwere, uye tularemia
• Chirwere chekuputira ura
• Lymphoma
• Systemic lupus erythematosus
• Kushandiswa kwemimwe mishonga, kusanganisira methyldopa, penicillin, uye quinidine

Cold agglutinins inogona kuitika ne:

• Zvirwere, senge mononucleous uye mycoplasma pneumonia
• Chicken pox (varicella)
• Cytomegalovirus hutachiona
• Kenza, inosanganisira lymphoma uye yakawanda myeloma
• Listeria monocytogenes
• Systemic lupus erythematosus
• Waldenstrom macroglobulinemia

Njodzi idiki asi dzinogona kusanganisira:

• Kuwedzera kubuda ropa
• Kufenda kana kunzwa kushaya musoro
• Hematoma (ropa rinoungana pasi peganda)
• Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

Kana chirwere chakabatana necold agglutinin chikafungidzirwa, munhu wacho anoda kuchengetedzwa.

Cold agglutinins; Weil-Felix kuita; Widal bvunzo; Warm agglutinins; Agglutinins

• Kuongorora ropa

Baum SG, Goldman DL. Mycoplasma zvirwere. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chitsiko 301.

Michel M, Jäger U. Autoimmune hemolytic kupererwa neropa. Muna: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Misimboti uye Maitiro. 7th ed. Philadelphia, PA: Elsevier; 2018: chits.

Quanquin NM, Cherry JD. Mycoplasma uye ureaplasma hutachiona. Mune: Cherry JD, Harrison GJ, Kaplan SL, Steinbach WJ, Hotez PJ, eds. Feigin naCherry's Bhuku reBhuku rePediatric Infectious Diseases. 8th ed. Philadelphia, PA: Elsevier; 2019: chitsuwa 196.