Vitamin B12 chikamu

Iyo vhitamini B12 nhanho kuongororwa kweropa kunoyera kuti yakawanda sei vitamini B12 iri muropa rako.

Muenzaniso weropa unodiwa.

Haufanire kudya kana kunwa kwemaawa matanhatu kusvika masere bvunzo isati yaitwa.

Mimwe mishonga inogona kukanganisa mhedzisiro yeiyi bvunzo. Anokuchengetedza hutano anokuudza kana uchifanira kurega kutora chero mishonga. Usamise chero mushonga usati wataura nemupi wako.

Mishonga inogona kukanganisa mhedzisiro yekuedzwa inosanganisira:

• Colchicine
• Neomycin
• Para-aminosalicylic acid
• Phenytoin

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanongonzwa kubaya kana kubaya. Mushure meizvozvo, panogona kuve nekurohwa kana kupwanya zvishoma. Izvi zvinokurumidza kuenda.

Muedzo uyu unowanzoitwa kana kumwe kuongorora kweropa kuchiratidza mamiriro anonzi megaloblastic anemia. Anonetseka kupererwa neropa chimiro che megaloblastic anemia inokonzerwa nehurombo hwevhitamini B12 yekumwa. Izvi zvinogona kuitika kana dumbu richiita kushomeka kwechinhu icho muviri chinoda kunyatsotora vhitamini B12.

Wako mupi anogona zvakare kukurudzira vhitamini B12 bvunzo kana iwe uine zvimwe zvehurongwa hwetsinga zviratidzo. Iyo yakaderera mwero weB12 inogona kukonzeresa kana kugwinha mumaoko nema makumbo, kushaya simba, uye kurasikirwa kwehuremu.

Mimwe mamiriro ezvinhu ayo bvunzo inogona kuitirwa anosanganisira:

• Kamwe kamwe nyonganiso yakaoma (delirium)
• Kurasikirwa kwehuropi basa (dementia)
• Dementia nekuda kwezvikonzero zvemagetsi
• Tsinga kusagadzikana, senge peripheral neuropathy

Maitiro akajairwa ari 160 kusvika 950 picograms pamamirilita (pg / mL), kana 118 kusvika 701 picomoles parita (pmol / L).

Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Mamwe marabhu anoshandisa zviyero zvakasiyana kana anogona kuyedza masampuli akasiyana. Taura nemupi wako nezve izvo zvaunoda mhinduro zvaunoda.

Maitiro asingasviki 160 pg / mL (118 pmol / L) chiratidzo chingangoita chekushomeka kwevhitamini B12. Vanhu vane kushomeka uku vanogona kuve kana kukudziridza zviratidzo.

Vakwegura vakuru vane vhitamini B12 chiyero chiri pasi pe100 pg / mL (74 pmol / L) vanogona zvakare kuve nezviratidzo. Kushomeka kunofanirwa kusimbiswa nekutarisa mwero wechinhu chiri muropa chinonzi methylmalonic acid. Chikamu chepamusoro chinoratidza kushomeka kwechokwadi kweB12.

Zvinokonzera kushomeka kwevhitamini B12 zvinosanganisira:

• Haina kukwana vitamini B12 mukudya (zvisingawanzo, kunze kwekudya kwakasimba kwezvinomera)
• Zvirwere zvinokonzera malabsorption (semuenzaniso, chirwere checeliac uye chirwere cheCrohn)
• Kushaikwa kwechinhu chemukati, puroteni inobatsira kuti ura hutore vhitamini B12
• Pamusoro peyakajairika kupisa kugadzirwa (semuenzaniso, ne hyperthyroidism)
• Kubata pamuviri

Iyo yakawedzera vhitamini B12 nhanho haina kujairika. Kazhinji, yakawandisa vhitamini B12 inobviswa mumuti.

Mamiriro ezvinhu anogona kuwedzera B12 chikamu anosanganisira:

• Chiropa chirwere (senge cirrhosis kana hepatitis)
• Myeloproliferative kusagadzikana (semuenzaniso, polycythemia vera uye chisingaperi myelogenous leukemia)

Pane njodzi shoma inosanganisirwa nekutorwa kweropa rako. Tsinga uye tsinga zvinosiyana muhukuru kubva kumunhu kuenda kune mumwe uye kubva kune rimwe divi remuviri kuenda kune rimwe. Kutora ropa kubva kune vamwe vanhu kunogona kunge kwakaoma kupfuura kubva kune vamwe.

Dzimwe njodzi dzinosangana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

• Kuwedzera kubuda ropa
• Kufenda kana kunzwa kushaya musoro
• Akawanda punctures ekutsvaga mutsinga
• Hematoma (kuwanda kweropa pasi peganda)
• Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

Cobalamin bvunzo; Anonetseka kupererwa neropa - vhitamini B12 nhanho

Marcogliese AN, Hongu DL. Zvishandiso zveiyo hematologist: anodudzira makomenti uye akasarudzwa mareferenzi kukosha kweanaonatal, kwevana, uye kwevanhu vakuru vanhu. Muna: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Misimboti uye Maitiro. 7th ed. Philadelphia, PA: Elsevier; 2018: chits. 162.

Mason JB, Booth SL. Mavhitamini, tsvaga zvicherwa, uye mamwe micronutrients. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chitsiko 205.