Munyori: William Ramirez
Zuva Rekusika: 15 Gunyana 2021
Gadziridza Zuva: 17 Mbudzi 2024
Anonim
Vitamin K and hemostasis
Vhidhiyo: Vitamin K and hemostasis

Zvemukati

Vitamin K vhitamini inowanikwa mumashizha emuriwo miriwo, broccoli, uye nhubu dzeBrussels. Zita iro vhitamini K rinobva mushoko reGerman "Koagulationsvitamin."

Mhando dzakasiyana dzevhitamini K dzinoshandiswa kutenderera pasirese semushonga. Vitamin K1 (phytonadione) uye vhitamini K2 (menaquinone) inowanikwa muNorth America. Vitamin K1 kazhinji ndiyo inosarudzika vhitamini K nekuti haina chepfu uye inoshanda nekukurumidza kune mamwe mamiriro.

Vitamin K inonyanya kushandiswa kumatambudziko ekuvhara ropa kana kudzoreredza iyo yekuonda kweropa mhedzisiro yewarfarin.Iyo inoshandiswawo kune mamwe akawanda mamiriro, asi hapana humbowo hwakanaka hwesainzi hwekutsigira hwakawanda hweizvi zvimwe zvinoshandiswa.

Natural Mishonga Inonzwisisika Dhatabhesi zvinowanisa kushanda kunoenderana neuchapupu hwesainzi zvinoenderana nezviyero zvinotevera: Zvinobudirira, Zvichida Zvinobudirira, Zvichida Zvinobudirira, Zvichida Hazvishande, Zvichida Hazvibatsiri, Hazvibatsiri, uye Huchakwana Huchapupu hweKutara.

Iko kushanda ratings kwe VITAMIN K zvinotevera:


Inoshanda kune ...

  • Zvinetso zvekubuda ropa mumwana achangozvarwa ane akadzika mavitamini K (hemorrhagic chirwere). Kupa vhitamini K1 nemuromo kana sepfuti mumhasuru kunobatsira kudzivirira matambudziko ekubuda ropa mune vacheche. Shots inoita kunge inoshanda zvakanakisa.
  • Akadzika masosi eropa rinovhara protein prothrombin (hypoprothrombinemia). Kutora vhitamini K1 nemuromo kana sejekiseni mutsinga kunogona kudzivirira nekubata matambudziko ekubuda ropa kune vanhu vane yakaderera prothrombin nekuda kwekushandisa mimwe mishonga.
  • Iyo isingawanzo, yakagara nhaka kubuda chirwere (vhitamini K-inoenderana nekuvhara zvinhu kushomeka kana VKCFD). Kutora vhitamini K nemuromo kana sejekiseni mutsinga kunogona kubatsira kudzivirira kubuda kweropa kune vanhu vane VKCFD.
  • Kudzoreredza ropa rekuonda mhedzisiro yewarfarin. Kutora vhitamini K1 nemuromo kana senge jekiseni mumutsipa kunogona kudzosera kuwanda kweropa kwakakonzerwa newarfarin. Nekudaro, kuisa jekiseni vhitamini K1 pasi peganda hakuite kunge kunoshanda. Kutora vhitamini K pamwe newarfarin zvakare zvinoita sekubatsira kudzikamisa nguva yekuvhara ropa kune vanhu vanotora warfarin. Inoshanda zvakanyanya kune vanhu vane yakaderera vhitamini K mazinga.

Zvichida inoshanda kune ...

  • Mapfupa asina simba uye anopwanya (osteoporosis). Kutora fomu yakasarudzika yevhitamini K2 inoita kunge inovandudza simba remapfupa uye kuderedza njodzi yekutyoka mukati mevakadzi vazhinji vakura vane mapfupa asina kusimba. Asi zvinoita sekunge hazvibatsire vakadzi vakuru vane mapfupa akasimba. Kutora vhitamini K1 inoita kunge inowedzera simba repfupa uye inogona kudzivirira kutsemuka kune vakadzi vakuru. Asi zvinogona kusashanda pamwe chete nevarume vakuru. Vitamin K1 inoita kunge isiri kuvandudza simba remapfupa kuvakadzi vasina kuenda kumwedzi kana kune vanhu vane chirwere cheCrohn.

Pamwe hazvibatsiri ...

  • Kubuda ropa mukati kana kutenderedza nzvimbo dzakazara mvura (ma ventricles) ehuropi (intraventricular hemorrhage). Kupa vhitamini K kuvakadzi vari panjodzi yekuzvarwa vasati vazvarwa zvinoita sekudzivirira kubuda kweropa muuropi hwevacheche vasati vazvarwa. Izvo zvakare zvinoita sekuderedza njodzi yekukuvara kwetsinga kunokonzerwa neropa iri.

Husingakwani humbowo hwekuyera kushanda kwe ...

  • Athletic performance. Kutsvagurudza kwekutanga kunoratidza kuti kutora vhitamini K2 nemuromo kunogona kuvandudza kurovedza muviri nekuwedzera basa remwoyo.
  • Chirwere cheropa chinoderedza huwandu hweprotein muropa inonzi hemoglobin (beta-thalassemia). Kutsvagurudza kwekutanga kunoratidza kuti kutora vhitamini K2 nemuromo pamwe necalcium uye vhitamini D kunogona kusimudzira mafupa muvana vane chirwere cheropa.
  • Gomarara repazamu. Kutsvagisa kunoratidza kuti kudya kwakanyanya kwevhitamini K2 kwakabatana nenjodzi yakaderera yekuva nekenza yemazamu.
  • Gomarara. Kumwe kutsvagurudza kwakabatanidza kudya kwakanyanya kwevhitamini K2, asi kwete vhitamini K1, ine njodzi yakadzikira yekufa nekenza. Asi kumwe kutsvagurudza kwakabatanidza kudya kwakanyanya kwevhitamini K1, asi kwete vhitamini K2, ine njodzi yakadzikira yekufa nekenza.
  • Kurwara. Kumwe kutsvagurudza kwakabatanidza kudya kwakanyanya kwevhitamini K2 ine njodzi yakaderera yekuwana maziso.
  • Gomarara rekoloni, gomarara remukoko. Kutsvagurudza kwekutanga kunoratidza kuti kudya kwakanyanya kwevhitamini K hakubatanidzwe nenjodzi yakadzikira yekenza yekoloni uye rectum.
  • Chirwere chemoyo. Yakawanda tsvagiridzo inoratidza kuti kwakawanda kudya kwekudya kwevhitamini K1 uye K2 kwakabatana nehuremu hwakadzikira hwehosha yemoyo. Asi kudya kwepamusoro kwevhitamini K1 hakuite sekuderedza njodzi yekufa nechirwere chemwoyo kazhinji.
  • Cystic fibrosis. Vanhu vane cystic fibrosis vane yakaderera huwandu hwevhitamini K nekuda kwematambudziko ekugaya mafuta. Kutora vhitamini K kunowedzera mavitamini K mazinga. Asi hazvizivikanwe kana zvichidzivirira matambudziko nekugwamba kweropa uye kukura kwemapfupa mune vanhu ava.
  • Kushungurudzika. Kutsvagurudza kwekutanga kwakawana kuti kudya kwakanyanya kwevhitamini K kubva muchikafu kwakabatana nenjodzi yakaderera yekuora mwoyo. Asi hapana chero kutsvagurudza pamusoro pekuti kutora vhitamini K zvinowedzera kunogona kudzikisa njodzi yekuora mwoyo.
  • Chirwere cheshuga. Kutsvagurudza kwekutanga kunoratidza kuti kutora multivitamin yakasimbiswa ne vhitamini K1 hakuderedze njodzi yekurwara neshuga zvichienzaniswa nekutora multivitamin yenguva dzose.
  • Acne-kunge mapundu anokonzereswa neimwe cancer mishonga. Vanhu vanopihwa imwe mhando yemushonga wekenza kazhinji vanokurumidza kubuda ganda. Tsvagurudzo yekutanga inoratidza kuti kuisa kirimu ine vhitamini K1 kunobatsira kudzivirira kuputika kweganda kune vanhu vanopihwa rudzi urwu rwemushonga. Asi kumwe kutsvagurudza kunoratidza kuti kushandisa chizoro chine vhitamini K hakuiti kuvandudza kumhanyisa uku muvanhu vakatozvigadzira.
  • Cholesterol yakakwira. Pane humbowo hwekutanga hwekuti vhitamini K2 inogona kudzikisa cholesterol mune vanhu vane dialysis ine yakakwira cholesterol mazinga.
  • Kenza yechiropa. Kutora vhitamini K2 zvinoita sekudzivirira kenza yechiropa kudzoka. Asi kumwe kutsvagurudza kwekutanga kunoratidza kuti kutora vitamini K2 kunoderedza njodzi yekenza yechiropa kune vanhu vane chiropa cirrhosis.
  • Chiropa chirwere. Kuisa jekiseni vhitamini K mumhasuru kwakabatanidzwa nenjodzi yakaderera yekufa kune vanhu vane chiropa chinokundikana.
  • Kenza yemapapu. Kutsvagurudza kwekutanga kunoratidza kuti kudya kwakanyanya kwevhitamini K2 kubva kuchikafu kunosanganisirwa nenjodzi yakadzikira yekenza yemapapu uye kufa kwakabatana nekenza yemapapu. Kudya kwekudya kwevhitamini K1 hakuratidzike kunge kwakabatana nenjodzi yakadzikira yezviitiko izvi.
  • Multiple sclerosis (MS). Interferon mushonga unobatsira vanhu vane MS. Mushonga uyu unowanzo kukonzera kuputika uye kupisa kweganda. Kutsvaga kwekutanga kunoratidza kuti kuisa vhitamini K cream zvine mwero kunoderedza mapundu uye kupisa mukati mevanhu vanorapwa ne interferon.
  • Rufu kubva chero chikonzero. Kudya kwakaderera kwevhitamini K kunogona kusunganidzwa nenjodzi yepamusoro yekufa kune vakura vane hutano.
  • Kenza yeprostate. Kutsvagurudza kwekutanga kwakawana kuti kudya kwakanyanya kudya kwevhitamini K2, asi kwete vhitamini K1, kwakabatana nenjodzi yakadzikira yekenza yeprostate.
  • Rheumatoid arthritis (RA). Kutsvagurudza kwekutanga kunoratidza kuti kutora vhitamini K2 pamwe nemushonga weArthritis kunodzora mamaki ekubatanidza kuzvimba zvirinani pane kutora mushonga weArthritis wega. Asi kutora vitamini K1 zvinoita sekuderedza zviratidzo zveRA.
  • Kurohwa. Kutsvakurudza kwevanhu kwakawana kuti kudya kwekudya kwevhitamini K1 hakubatanidzwi nehutachiona hwehutachiona.
  • Kupwanya.
  • Kunopisa.
  • Mavanga.
  • Tsinga dzemhungu.
  • Tambanudza mamaki.
  • Kuzvimba.
  • Mamwe mamiriro.
Humwe humbowo hunodiwa kuyera vhitamini K kune izvi zvinoshandiswa.

Vitamin K vhitamini yakakosha inodikanwa nemuviri wekugwamba kweropa, kuvaka mapfupa, uye mamwe maitiro akakosha.

Kana ikatorwa nemuromo: Iwo mafomu maviri evitamini K (vhitamini K1 uye vhitamini K2) ANOFANIRA KUCHENGETEKA kuvanhu vazhinji kana akatorwa nemazvo. Vitamin K1 10 mg zuva nezuva uye vhitamini K2 45 mg zuva nezuva zvakashandiswa zvakachengeteka kweanosvika makore maviri. Vanhu vazhinji havawani chero mhedzisiro pavanotora vhitamini K muhuwandu hwakakurudzirwa zuva rega rega. Asi vamwe vanhu vanogona kushushikana mudumbu kana manyoka.

Kana ichishandiswa paganda: Vitamin K1 iri ZVINOKOSHA KUNENGE kune vanhu vazhinji kana ichizorwa sekirimu ine 0.1% vhitamini K1.

Kana yapiwa na IV: Mafomu maviri evitamini K (vhitamini K1 uye vhitamini K2) ndeaya ZVIMWE ZVAKANAKA kune vanhu vazhinji kana vakajowa mutsinga zvakakodzera.

Special matanho & yambiro:

Kubata uye kuyamwisa: Kana ikatorwa muhuwandu hwakakurudzirwa zuva rega rega, vhitamini K iri ZVIMWE ZVAKANAKA kune vakadzi vane pamuviri uye vanoyamwisa. Usashandise huwandu hwakawanda pasina kuraira kwenyanzvi yako yehutano.

Vana: Mhando yevhitamini K inozivikanwa sevhitamini K1 iri ZVIMWE ZVAKANAKA kune vana kana vakatorwa nemuromo kana kujowa mumuviri zvakakodzera.

Chirwere cheitsvo: Vitamini K yakawandisa inogona kukuvadza kana iwe uri kugamuchira kurapwa kwedialysis nekuda kwechirwere cheitsvo.

Chiropa chirwere: Vitamin K haina basa pakurapa matambudziko ekugwamba anokonzerwa nechirwere chakakomba chechiropa. Muchokwadi, kuwanda kwevhitamini K kunogona kuita kuti matambudziko ekugwamba anyanye kukura muvanhu ava.

Yakaderedzwa bile secretion: Vanhu vane yakaderera bile secretion avo vari kutora vhitamini K vangangoda kutora yekuwedzera bile munyu pamwe ne vhitamini K kuona vhitamini K kutora.

Zvikuru
Usatore musanganiswa uyu.
Warfarin (Coumadin)
Vitamin K inoshandiswa nemuviri kubatsira kuvhara ropa. Warfarin (Coumadin) inoshandiswa kudzora kuvhara ropa. Nekubatsira iro rinovhara ropa, vhitamini K inogona kudzikisira kushanda kwewarfarin. Iva nechokwadi chekuongororwa ropa rako nguva dzose. Muyero wewarfarin yako ungangoda kuchinjwa.
Coenzyme Q10
Coenzyme Q10 yakafanana nemakemikari yakafanana nevhitamin K uye, savhitamini K, inogona kusimudzira kuvhara ropa. Kushandisa zvigadzirwa zviviri izvi pamwe chete zvinogona kukurudzira kuvhara ropa kupfuura kushandisa chete. Iko kusanganisa kunogona kuve dambudziko kune vanhu vari kutora warfarin kunonoka kugwamba kweropa. Coenzyme Q10 pamwe nevhitamini K inogona kukurira zvinokonzerwa newarfarin uye inogona kubvumira ropa kuvhara.
Tiratricol
Pane kunetsekana kuti tiratricol inogona kukanganisa vhitamini K basa mukuvhara ropa.
Vhitamini A
Mune mhuka, mwero wakakura wevhitamini A unokanganisa kugona kwevhitamini K yekuvhara ropa. Asi hazvizivikanwe kana izvi zvinoitikawo muvanhu.
Vhitamini E
Kuwanda kwemavhitamini E (semuenzaniso mukuru kupfuura mazana masere / zuva) kunogona kuita kuti vhitamini K isanyanya kushanda mukuvhara ropa. Mune vanhu vari kutora warfarin kuchengetedza ropa ravo kubva mukugwamba, kana kune vanhu vane yakaderera vhitamini K inodya, yakakwira madhayamini evitamini E inogona kuwedzera njodzi yekubuda ropa.
Mafuta uye chikafu chine mafuta
Kudya chikafu chine bhotela kana mamwe mafuta ezvekudya pamwe chete nekudya zvine vhitamini K, senge sipinachi, zvinoita kunge kunowedzera kufutisa kwevhitamini K.
Iyi inotevera doses yakadzidzwa mukutsvaga kwesainzi:

VAKURU

Nemuromo:
  • Yemapfupa asina kusimba uye anopwanya (osteoporosis): Iyo MK-4 fomu yevhitamini K2 yakatorwa mumadhosi e45 mg zuva nezuva. Zvakare, vhitamini K1 yakatorwa muzvikamu zve110 mg zuva nezuva.
  • Kune isingawanzo, nhaka yekubuda ropa kusagadzikana (vhitamini K-inoenderana nekuvhara zvinhu kushomeka kana VKCFD): 10 mg vhitamini K yakatorwa 2-3 nguva pasvondo.
  • Yekudzoreredza iro ropa rinotetepa mhedzisiro yewarfarin: Imwe chete muyero we 1-5 mg wevhitamini K1 unowanzo shandiswa kudzoreredza mhedzisiro yekutora yakawandisa warfarin. Iyo chaiyo dosi inodiwa inotemerwa neyeyabvunzo bvunzo inonzi iyo INR. Mazuva ese madhayeti e100-200 micrograms evitamini K ave achishandiswa kuvanhu vanotora warfarin yenguva refu-vasina kugadzikana kweropa.
NENHURE:
  • Kune isingawanzo, nhaka yekubuda ropa kusagadzikana (vhitamini K-inoenderana nekuvhara zvinhu kushomeka kana VKCFD): 10 mg vhitamini K yakabayiwa mutsinga. Kakawanda sei jekiseni iri rinopihwa rinotariswa nebvunzo bvunzo inonzi iyo INR.
  • Yekudzoreredza iro ropa rinotetepa mhedzisiro yewarfarin: Dozi imwe chete ye0,5-3 mg yevhitamini K1 inowanzo shandiswa. Iyo chaiyo dosi inodiwa inotemerwa neyeyabvunzo bvunzo inonzi iyo INR.
VANA

Nemuromo:
  • Nezvinetso zvekubuda ropa muvana vachangozvarwa vane huwandu hwakaderera hwevitamin K (hemorrhagic chirwere): 1-2 mg vhitamini K1 yakapihwa muzvikamu zvitatu kupfuura masvondo masere. Zvakare madhizaina ane 1 mg yevhitamini K1, 5 mg yevhitamini K2, kana 1-2 mg yevhitamini K3 yakashandiswa.
NENHURE:
  • Nezvinetso zvekubuda ropa muvana vachangozvarwa vane huwandu hwakaderera hwevitamin K (chirwere chehemorrhagic: 1 mg vhitamini K1 yakapihwa sepfuti mumhasuru.
Iko hakuna kukwana kwesainzi ruzivo rwekutsvaga yakakurudzirwa yekudya mvumo (RDAs) yevhitamini K, saka zuva nezuva zvakakwana kudya (AI) kurudziro zvinoshandiswa pachinzvimbo: Iyo AI ndeiyi: vacheche 0-6 mwedzi, 2 mcg; vacheche mwedzi 7-12, 2.5 mcg; vana 1-3 makore, 30 mcg; vana makore 4-8, 55 mcg; vana makore 9-13, 60 mcg; vachiri kuyaruka 14-18 makore (kusanganisira avo vane nhumbu kana kuyamwisa), 75 mcg; varume vanopfuura makore 19, 120 mcg; vakadzi vanopfuura makore gumi nemapfumbamwe (kusanganisira avo vane pamuviri nekuyamwisa), 90 mcg.

2-methyl-1,4-naphthoquinone, 2-methyl-3-phytyl-1,4-naphthoquinone, 4-Amino-2-Methyl-1-Naphthol, Fat-Soluble Vitamin, Menadiol, Menadiol Acetate, Menadiol Diacetate, Menadiol Sodiamu Diphosphate, Menadiol Sodium Phosphate, Menadiolum Solubile Methynaphthohydroquinone, Menadione, Ménadione, Menadione Sodium Bisulfite, Menaquinone, Ménaquinone, Menatetrenone, Menatétrenone, Phytonadione, Methylphytyl Naphtylosone, Phylonone, .

Kuti udzidze zvakawanda nezvekuti chinyorwa ichi chakanyorwa sei, ndapota ona iyo Natural Mishonga Inonzwisisika Dhatabhesi nzira.


  1. Xiong Z, Liu Y, Chang T, uye al. Mhedzisiro yevhitamin K1 pakupona kwevarwere vane chisingaperi chiropa kutadza: Yekudzokororazve cohort kudzidza. Mushonga (Baltimore). 2020; 99: e19619. Wona zvisingabvumirwe.
  2. Turck D, Bresson JL, Burlingame B, et al. Dhayeti yekureva kukosha kwevhitamini K. EFSA J. 2017; 15: e04780. Wona zvisingabvumirwe.
  3. Shea MK, Barger K, Booth SL, uye al. Vitamin K chinzvimbo, chirwere chemwoyo, uye zvese-zvinokonzera kufa: mutori wechikamu-meta-ongororo yevatatu veUS makosi. Ndiri J Kliniki Nutriti. 2020; 111: 1170-1177. Wona zvisingabvumirwe.
  4. Kuang X, Liu C, Guo X, Li K, Deng Q, Li D. Iko kusanganiswa kwevhitamini K uye vhitamini D pahunhu hwemapfupa emunhu: meta-ongororo yemiedzo yakasarudzika inodzorwa. Chikafu Chinoshanda. 2020; 11: 3280-3297. Wona zvisingabvumirwe.
  5. Jagannath VA, Thaker V, Chang AB, Mutengo AI. Vitamin K yekuwedzera yecystic fibrosis. Cochrane Dhatabhesi Syst Rev. 2020; 6: CD008482. Wona zvisingabvumirwe.
  6. Hashimoto H, Iwasa S, Yanai-Takahashi T, et al. Randomized, Double-Blind, Placebo-Inodzorwa Phase? Dzidza nezve Kubudirira uye Kuchengetedzwa kweVitamin K1 Mafuta eCetuximab kana Panitumumab-Yakakonzera Acneiform Eruptions-VIKTORIA Study. Gan KuKagaku Ryoho. 2020; 47: 933-939. Wona zvisingabvumirwe.
  7. Mota A, Bradley T, Wright K, et al. Migumisiro yevhitamin K pamafupa emamineral density uye kutsemuka muvakuru: yakagadziriswa yakarongeka ongororo uye meta-ongororo yeanoteedzana inodzorwa miedzo. Osteoporos Int 2019; 30: 1543-59. doi: 10.1007 / s00198-019-04949-0. Wona zvisingabvumirwe.
  8. Chen HG, Sheng LT, Zhang YB, et al. Sangano revhitamini K ine zviitiko zvemoyo uye zvese-zvinokonzeresa kufa: ongororo yakarongeka uye meta-ongororo. Eur J Nutriti 2019; 58: 2191-205. doi: 10.1007 / s00394-019-01998-3. Wona zvisingabvumirwe.
  9. Oikonomaki T, Papasotiriou M, Ntrinias T, et al. Mhedzisiro yevhitamini K2 yekuwedzera pane vascular calcification muvarwere vehemodialysis: yegore-rekutevera-rakateedzana muyedzo. Int Urol Nephrol 2019; 51: 2037-44. doi: 10.1007 / s11255-019-02275-2. Wona zvisingabvumirwe.
  10. Löwensteyn YN, Jansen NJG, van Heerde M, et al. Kuwedzera muyero wevitamini K yekudzivirira uye maitiro ayo pakubata ropa. Eur J Pediatr 2019; 178: 1033-42. doi: 10.1007 / s00431-019-03391-y. Wona zvisingabvumirwe.
  11. Shishavan NG, Gargari BP, Jafarabadi MA, Kolahi S, Haggifar S, Noroozi S. Vitamin K yekuwedzera haina kuchinja mamakisi ekupwanya uye chimiro chekiriniki mune varwere vane rheumatoid arthritis. Int J Vitam Nutriti Res. 2018; 88 (5-6): 251-257. Wona zvisingabvumirwe.
  12. Bolzetta F, Veronese N, Stubbs B, uye al. Hukama huripo pakati pekudya vhitamini K uye zviratidzo zvekushushikana mukukura kwekukura: Yeyambuka-chikamu chikamu kuongororwa kubva kune hombe boka redzidzo. Nutrients. 2019; 11. pii: E787. Wona zvisingabvumirwe.
  13. McFarlin BK, Henning AL, Anobata AS. Kunwa kwemuromo kwevhitamini K2 kwemavhiki masere inosanganisirwa nekuwedzera kwakanyanya kwemoyo kuburitsa panguva yekurovedza muviri. Imwe Ther Ther Med. 2017; 23: 26-32. Wona zvisingabvumirwe.
  14. Camacho-Barcia ML, Bulló M, Garcia-Gavilán JF, et al. Sangano rezvokudya vhitamini K1 kudya pamwe nechiitiko chekuvhiyiwa kwekati mune vanhu vakuru veMediterranean: ongororo yechipiri yechiratidziro chekiriniki. JAMA Ophthalmol. 2017; 135: 657-61. Wona zvisingabvumirwe.
  15. Holbrook A, Schulman S, Witt DM, uye al. Uchapupu-hwakavakirwa manejimendi yeanticoagulant Therapy: Antithrombotic Therapy uye Kudzivirira kweTrombombus, 9th ed: American College yeChechi Vanachiremba Uchapupu-Hwakavakirwa Pakiriniki Yekudzidzira Nhungamiro. Chifuva 2012; 141: e152S-e184S. Wona zvisingabvumirwe.
  16. Ozdemir MA, Yilmaz K, Abdulrezzak U, Muhtaroglu S, Patiroglu T, Karakukcu M, Unal E. Kubudirira kwevhitamini K2 uye calcitriol mubatanidzwa pane thalassemic osteopathy. J Pediatr Hematol Oncol. 2013; 35: 623-7. Wona zvisingabvumirwe.
  17. Pinta F, Ponzetti A, Spadi R, Fanchini L, Zanini M, Mecca C, Sonetto C, Ciuffreda L, Racca P. Pilot kiriniki kutongwa pamusoro pekubudirira kwekushandisa kweprophylactic kwevhitamini K1-based cream (Vigorskin) kudzivirira cetuximab-induced kuputika kweganda kune varwere vane metastatic colorectal cancer. Kliniki Colorectal Kenza. 2014; 13: 62-7. Wona zvisingabvumirwe.
  18. O'Connor EM, Grealy G, McCarthy J, Desmond A, Craig O, Shanahan F, Cashman KD. Mhedzisiro ye phylloquinone (vhitamini K1) yekuwedzera kwemwedzi gumi nemaviri pane indices yehutano hwevhitamini K uye hutano hwepfupa mune vakuru varwere vane chirwere cheCrohn. Br J Nutriti. 2014; 112: 1163-74. Wona zvisingabvumirwe.
  19. Lanzillo R, Moccia M, Carotenuto A, Vacchiano V, Satelliti B, Panetta V, Brescia Morra V. Vitamin K cream inoderedza maitiro panzvimbo yejekiseni kune varwere vanodzokedzana-vachiregedzera sclerosis yakawanda inorapwa ne subcutaneous interferon beta - VIKING kudzidza. Mult Scler. 2015; 21: 1215-6. Wona zvisingabvumirwe.
  20. Juanola-Falgarona M, Salas-Salvadó J, Martínez-González MÁ, Corella D, Estruch R, Ros E, Fitó M, Arós F, Gómez-Gracia E, Fiol M, Lapetra J, Basora J, Lamuela-Raventós RM, Serra -Majem L, Pintó X, Muñoz MÁ, Ruiz-Gutiérrez V, Fernández-Ballart J, Bulló M. Kudya kudya kwevhitamini K kwakabatana zvakanyanya nenjodzi yekufa. J Nutriti. 2014; 144: 743-50. Wona zvisingabvumirwe.
  21. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Vitamini K2 inoita chinzvimbo mukudzivirira uye kurapwa kweosteoporosis yevakadzi ve postmenopausal: meta-ongororo yemiedzo yakasarudzika inodzorwa. Osteoporos Int. 2015; 26: 1175-86. Wona zvisingabvumirwe.
  22. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 yekuwedzera mune hemodialysis varwere: yakasarudzika-yekutsvaga-kutsvaga kudzidza. Nephrol Dial Kudyara. 2014; 29: 1385-90. Wona zvisingabvumirwe.
  23. Abdel-Rahman MS, Alkady EA, Ahmed S. Menaquinone-7 senge inoverengeka mishonga yekurapa pakurapa rheumatoid arthritis: Kliniki yekudzidza. Eur J Pharmacol. 2015; 761: 273-8. Wona zvisingabvumirwe.
  24. Dennis VC, Ripley TL, Planas LG, uye Beach P. Chikafu vhitamini K mumuromo anticoagulation varwere: zvechiremba maitiro uye ruzivo munzvimbo dzekunze. J Pharm Technol 2008; 24: 69-76.
  25. Pathak A, Hamm CR, Eyal FG, Walter K, Rijhsinghani A, naBohlman M. Maternal mavitamini K manejimendi ekudzivirira kubuda kweropa mukati mevacheche vasati vatanga. Kuongorora kwevana 1990; 27: 219A.
  26. Eisai Co. Ltd. Eisai anozivisa iyo yepakati ongororo yeant-osteoporosis kurapwa mushure-kushambadzira kutsvagurudza mabhenefiti e menatetrenone sechikamu cheMinistry of Health, Labor and Welfare's Pharmacoepidemiological Drug Review Chirongwa. 2005;
  27. Shiraki M. Vitamin K2 mhedzisiro panjodzi yekutyoka uye pane lumbar bone mineral density muosteoporosis - yakasarudzika inotarisirwa yakavhurika-chitaridzi 3-gore rekudzidza. Osteoporos Int 2002; 13: S160.
  28. Greer, FR, Marshall, SP, Severson, RR, Smith, DA, Shearer, MJ, Pace, DG, uye Joubert, PH Kugadzira micellar nyowani nyowani yemumuromo vhitamini K prophylaxis: kurongedzwa kusarongeka nekuenzaniswa kwemuviri mumazamu anodyiswa vacheche. . Arch. Dis. Mwana 1998; 79: 300-305. Wona zvisingabvumirwe.
  29. Wentzien, T. H., O'Reilly, R. A., naKearns, P. J. Anofungidzira kuongororwa kweanticoagulant inodzokororwa nemuromo vhitamini K1 ichiri kuenderera warfarin kurapa isina kuchinjika. Chifuva 1998; 114: 1546-1550. Wona zvisingabvumirwe.
  30. Duong, T. M., Plowman, B. K., Morreale, A. P., naJanetzky, K. Kudzokororazve uye kutarisira kuongororwa kwekurapwa kwevarwere vakawandisa. Pharmacotherapy 1998; 18: 1264-1270. Wona zvisingabvumirwe.
  31. Sato, Y., Honda, Y., Kuno, H., naOizumi, K. Menatetrenone anokurudzira osteopenia mukusashandisa-zvakakanganiswa mitezo yevhitamini D- uye K-inoshaya sitiroko varwere. Bone 1998; 23: 291-296. Wona zvisingabvumirwe.
  32. Kamwe, M.A, Donovan, D., Harrison, L., McGinnis, J., naGinsberg, J. Low-dose yemumuromo vhitamini K inodzora zvine mutsindo pamusoro-anticoagulation nekuda kwewarfarin. Thromb.Haemost. 1998; 79: 1116-1118. Wona zvisingabvumirwe.
  33. Lousberg, T. R., Witt, D. M., Beall, D. G., Carter, B. L., naMalone, D. C. Kuongorora kweanopedzisa anticoagulation muboka modhi yekuchengetedza hutano sangano. Arch.Intern.Med. 3-9-1998; 158: 528-534. Wona zvisingabvumirwe.
  34. Fetrow, C.W, Overlock, T., uye Leff, L. Kupesana kwewarfarin-inosimudzira hypoprothrombinemia nekushandisa yakaderera-dosi subcutaneous vhitamini K1. J.Clin.Pharmacol. 1997; 37: 751-757. Wona zvisingabvumirwe.
  35. Weibert, R.T, Le, D.T, Kayser, S. R., uye Rapaport, S. I. Kugadziriswa kweanopedza anticoagulation ine yakaderera-dosi yemuromo vhitamini K1. Ann.Intern.Med. 6-15-1997; 126: 959-962. Wona zvisingabvumirwe.
  36. Beker, L.T, Ahrens, R. A., Fink, R. J., O'Brien, M. E., Davidson, K. W., Sokoll, L. J., naSadowski, J. A. Mhedzisiro yevhitamini K1 yekuwedzera pane vhitamini K chinzvimbo mucystic fibrosis varwere. J.Pediatr. Gastroenterol. Nutriti. 1997; 24: 512-517. Wona zvisingabvumirwe.
  37. Bakhshi, S., Deorari, A. K., Roy, S., Paul, V. K., naSingh, M. Kudzivirira kwehutachiona hwehutachiona hwehutachiona hwehutachiona hunobva pamatanho ePIVKA-II: muromo nemuromo wenzira. Indian Pediatr. 1996; 33: 1040-1043. Wona zvisingabvumirwe.
  38. Makris, M., Greaves, M., Phillips, WS, Kicheni, S., Rosendaal, FR, uye Preston, EF Emergency yemuromo anticoagulant inodzosera: iko kushanda kweiyo infusions yeplazzi yechando yeplasma uye yekugwamba chinhu chinotarisana nekugadziriswa kweiyo coagulopathy . Thromb.Haemost. 1997; 77: 477-480. Wona zvisingabvumirwe.
  39. Ulusahin, N., Arsan, S., uye Ertogan, F. Mhedzisiro yemuromo uye yepamuviri vhitamini K prophylaxis paPIVKA-II yekuyera paramita mune vacheche vayamwisa muTurkey. Turk. J. Nyanzvi. 1996; 38: 295-300. Wona zvisingabvumirwe.
  40. Gijsbers, B. L., Jie, K. S., naVermeer, C. Mhedzisiro yekugadzirwa kwechikafu pavhitamin K yekumwa muvanhu vanozvipira. Br. J. Nutriti. 1996; 76: 223-229. Wona zvisingabvumirwe.
  41. Thijssen, H.H uye Drittij-Reijnders, M. J. Vitamin K chinzvimbo mumatumbu evanhu: kuunganidzwa kwetissue-phylloquinone uye menaquinone-4. Br. J. Nutriti. 1996; 75: 121-127. Wona zvisingabvumirwe.
  42. White, R.H, McKittrick, T., Takakuwa, J., Callahan, C., McDonell, M., naFihn, S. Management uye kufungidzira kweropa rinotyisidzira hupenyu panguva yewarfarin kurapa. National Consortium yeAnticoagulation Makiriniki. Arch.Intern.Med. 6-10-1996; 156: 1197-1201. Wona zvisingabvumirwe.
  43. Sharma, R. K., Marwaha, N., Kumar, P., naNarang, A. Mhedzisiro yemumuromo mvura inogadzikana vhitamini K pamatanho ePIVKA-II muvacheche. Indian Pediatr. 1995; 32: 863-867. Wona zvisingabvumirwe.
  44. Brousson, M. A. naKlein, M. C. Makakatanwa akakomberedza kuiswa kwevhitamini K kuvacheche: ongororo. CMAJ. 2-1-1996; 154: 307-315. Wona zvisingabvumirwe.
  45. Cornelissen, E. A., Kollee, L. A., van Lith, T. G., Motohara, K., naMonnens, L. A. Kuongororwa kwedhivhosi yezuva nezuva yemakumi maviri nemashanu emamirigiramu vhitamini K1 kudzivirira kushomeka kwevhitamini K muvacheche vanoyamwiswa. J.Pediatr. Gastroenterol. Nutriti. 1993; 16: 301-305. Wona zvisingabvumirwe.
  46. Hogenbirk, K., Peters, M., Bouman, P., Sturk, A., uye Buller, HA Mhedzisiro yefomula maringe nekuyamwisa uye exogenous vhitamini K1 yekuwedzera pane kutenderera kwehuwandu hwevhitamini K1 uye vhitamini K-inoenderana nekuvhara zvinhu vachangozvarwa. Eur.J Mucheche. 1993; 152: 72-74. Wona zvisingabvumirwe.
  47. Cornelissen, E. A., Kollee, L. A., De Abreu, R. A., Motohara, K., naMonnens, L. A. Kudzivirira kushomeka kwevhitamin K muhucheche nehutongi hwevhiki nevhiki hwevitamini K. Acta Paediatr. 1993; 82: 656-659. Wona zvisingabvumirwe.
  48. Klebanoff, M. A., Verenga, J. S., Mills, J. L., uye Shiono, P. H. Njodzi yekenza yehucheche mushure mekuratidzwa kweononatal kune vhitamini K. N.Engl.J.Med. 9-23-1993; 329: 905-908. Wona zvisingabvumirwe.
  49. Dickson, R. C., Stubbs, T. M., naLazarchick, J. Antenatal vhitamini K kurapa kwemucheche-ane huremu-huremu hwevacheche. Ndiri. J. Obstet.Gynecol. 1994; 170 (1 Pt 1): 85-89. Wona zvisingabvumirwe.
  50. Pengo, V., Banzato, A., Garelli, E., Zasso, A., uye Biasiolo, A. Kuchinja kwehuwandu hwekuita anticoagulation yenguva dzose: yakaderera muromo wephytonadione (vitamini K1) uchienzaniswa newarfarin kurega. Ropa Coagul. Fibrinolysis 1993; 4: 739-741. Wona zvisingabvumirwe.
  51. Thorp, JA, Parriott, J., Ferrette-Smith, D., Meyer, BA, Cohen, GR, naJohnson, J. Antepartum vhitamini K uye phenobarbital yekudzivirira kubuda kweropa mukati mevacheche vasati vazvarwa. muedzo we placebo Obstet.Gynecol. 1994; 83: 70-76. Wona zvisingabvumirwe.
  52. Maurage, C., Dalloul, C., Moussa, F., Cara, B., Dudragne, D., Shumba, N., uye Amedee-Manesme, O. [Kubudirira kwekutongwa kwemuromo kwemhinduro ye micellaar yevhitamini K panguva nguva yekuzvarwa]. Arch.Pediatr. 1995; 2: 328-332. Wona zvisingabvumirwe.
  53. Taberner, D., Thomson, J. M., naPoller, L. Kufananidza kweprothrombin yakaoma kuisa pfungwa uye vhitamini K1 mumuromo inodzora anticoagulant. Br.Med.J. 7-10-1976; 2: 83-85. Wona zvisingabvumirwe.
  54. Glover, J. J. naMorrill, G. B. Kurapa kwekuchengetedza kwevarwere vakawandisa. Chifuva 1995; 108: 987-990. Wona zvisingabvumirwe.
  55. Jie, K. S., Bots, M. L., Vermeer, C., Witteman, J. C., naGrobbee, D. E. Vitamin K kudya uye maosteocalcin mazinga evakadzi vane uye vasina aortic atherosclerosis: chidzidzo chevanhu. Atherosclerosis 1995; 116: 117-123. Wona zvisingabvumirwe.
  56. Sutherland, J. M., Glueck, H. I., naGleser, G. Hemorrhagic chirwere chemucheche. Kuyamwisa mazamu sechinhu chakakosha muhutachiona. Ndiri. JDis Mwana. 1967; 113: 524-533. Wona zvisingabvumirwe.
  57. Motohara, K., Endo, F., naMatsuda, I. Kushayikwa kweVitamin K muvacheche vanoyamwiswa pamwedzi mumwe chete zera. J.Pediatr. Gastroenterol. Nutriti. 1986; 5: 931-933. Wona zvisingabvumirwe.
  58. Pomerance, J. J., Teal, J. G., Gogolok, J. F., Brown, S., naStewart, M. E. Maternally inotungamirwa vhitamini yekuzvitakura. Obstet.Gynecol. 1987; 70: 235-241. Wona zvisingabvumirwe.
  59. O'Connor, M. E. naAddiego, J. E., Jr. Kushandiswa kwemuromo vhitamini K1 kudzivirira chirwere chinobuda ropa chemucheche achangozvarwa. J.Pediatr. 1986; 108: 616-619. Wona zvisingabvumirwe.
  60. Morales, W. J., Angel, J. L., O'Brien, W. F., Knuppel, R. A., naMarsalisi, F. Kushandiswa kwehutachiona hwehutachiona hwekudzivirira hutachiona hwekubuda kweropa. Ndiri. J. Obstet.Gynecol. 1988; 159: 774-779. Wona zvisingabvumirwe.
  61. Motohara, K., Endo, F., naMatsuda, I. Mhedzisiro yevhitamini K manejimendi pane acarboxy prothrombin (PIVKA-II) mazinga muvacheche. Lancet 8-3-1985; 2: 242-244. Wona zvisingabvumirwe.
  62. Propranolol inodzivirira kutanga kwematumbo kubuda ropa mune vasiri-ascitic cirrhotic varwere. Wokupedzisira mushumo we multicenter randomized kutongwa. Iyo Italian Multicenter Chirongwa chePropranolol mukudzivirira Kubuda ropa. J.Hepatol. 1989; 9: 75-83. Wona zvisingabvumirwe.
  63. Kazzi, N. J., Ilagan, N. B., Liang, K. C., Kazzi, G. M., Poland, R. L., Grietsell, L. A., Fujii, Y., uye maBrans, Y. W. Maternal manejimendi vhitamini K haigadzirise huwandu hwekuumbana kwevanotangira vacheche. Pediatrics 1989; 84: 1045-1050. Wona zvisingabvumirwe.
  64. Yang, Y. M., Simon, N., Maertens, P., Brigham, S., naLiu, P. Maternal-fetal kutakura kwevhitamini K1 nemhedzisiro yayo pakubatana muvacheche vasati vazvarwa. J.Pediatr. 1989; 115: 1009-1013. Wona zvisingabvumirwe.
  65. Martin-Lopez, JE, Carlos-Gil, AM, Rodriguez-Lopez, R., Villegas-Portero, R., Luque-Romero, L., uye Flores-Moreno, S. [Prophylactic vhitamini K yevhitamini K inoshaya kubuda ropa kwe achangozvarwa.]. Farm.Hosp. 2011; 35: 148-55. Wona zvisingabvumirwe.
  66. Chow, C. K. Kudya kwekudya kwemanaquinones uye njodzi yekenza chiitiko uye kufa. Ndiri. J. Clin. Nutr. 2010; 92: 1533-1534. Wona zvisingabvumirwe.
  67. Rees, K., Guraewal, S., Wong, YL, Majanbu, DL, Mavrodaris, A., Stranges, S., Kandala, NB, Clarke, A., naFranco, OH Vitamin K kushandiswa kunosanganiswa ne cardio-metabolic. kusagadzikana? Kuongorora kwakarongeka. Maturitas 2010; 67: 121-128. Wona zvisingabvumirwe.
  68. Napolitano, M., Mariani, G., naLapecorella, M. Hereditary inosanganisa kushomeka kwevhitamini K-inoenderana nekuvhara zvinhu. Nherera. J. Kazhinji. 2010; 5:21. Wona zvisingabvumirwe.
  69. Dougherty, K. A., Schall, J. I., uye Stallings, V. A. Suboptimal vhitamini K chinzvimbo kunyangwe kuwedzerwa muvana nevakuru vechidiki vane cystic fibrosis. Ndiri. J. Clin. Nutr. 2010; 92: 660-667. Wona zvisingabvumirwe.
  70. Novotny, J. A., Kurilich, A. C., Britz, S. J., Baer, ​​D. J., naClevidence, B. A. Vitamin K kuyamwa uye kinetics muzvidzidzo zvevanhu mushure mekushandisa 13C-yakanyorwa phylloquinone kubva kare. Br. J. Nutriti. 2010; 104: 858-862. Wona zvisingabvumirwe.
  71. Jorgensen, F. S., Felding, P., Vinther, S., naAndersen, G. E. Vitamin K kusvika kunevana. Peroral maringe neyakagadziriswa intramuscular. Acta Paediatr.Scand. 1991; 80: 304-307. Wona zvisingabvumirwe.
  72. Nimptsch, K., Rohrmann, S., Kaaks, R., naLinseisen, J. Kudya kwevhitamini K inodya zvine chekuita nekenza chiitiko uye kufa: zvinobva kuboka reHeidelberg reEuropean Prospective Investigation kuCancer and Nutrition (EPIC-Heidelberg ). Ndiri. J. Clin. Nutr. 2010; 91: 1348-1358. Wona zvisingabvumirwe.
  73. Yamauchi, M., Yamaguchi, T., Nawata, K., Takaoka, S., uye Sugimoto, T. Hukama pakati peascarboxylated osteocalcin uye vhitamini K inotora, bone pfupa, uye bone mineral density mune vakadzi vane hutano. Kliniki. Nutriti. 2010; 29: 761-765. Wona zvisingabvumirwe.
  74. Shea, MK, Booth, SL, Gundberg, CM, Peterson, JW, Waddell, C., Dawson-Hughes, B., uye Saltzman, E. Kufutisa kwevakuru kunosanganisirwa neAdipose tishu kuwanda kwevhitamini K uye zvinopesana zvine chekuita nekutenderera. zviratidzo zvevitamin K chimiro mune varume nevakadzi. J.Nutr. 2010; 140: 1029-1034. Wona zvisingabvumirwe.
  75. Kamwe, C. A., Crosby, D. D., naHenderson-Smart, D. J. Vitamin K vasati vaberekwa vasati vazvarwa kuitira kudzivirira neonatal periventricular haemorrhage. Cochrane.Database.Syst.Rev. 2010; CD000229. Wona zvisingabvumirwe.
  76. Iwamoto, J. [Anti-kutsemuka kushanda kwevhitamini K]. Kliniki Calcium 2009; 19: 1805-1814. Wona zvisingabvumirwe.
  77. Stevenson, M., Lloyd-Jones, M., naPapaioannou, D. Vitamin K yekudzivirira kutsemuka muvakadzi vakuru: kuongorora kwakarongeka uye kuongorora kwehupfumi. Hutano Technol Kuongorora. 2009; 13: iii-134. Wona zvisingabvumirwe.
  78. Yoshiji, H., Noguchi, R., Toyohara, M., Ikenaka, Y., Kitade, M., Kaji, K., Yamazaki, M., Yamao, J., Mitoro, A., Sawai, M., Yoshida, M., Fujimoto, M., Tsujimoto, T., Kawaratani, H., Uemura, M., naFukui, H. Kusanganiswa kwevhitamini K2 uye angiotensin-inoshandura enzyme inhibitor inogadzirisa kudzokororazve kwehepatocellular carcinoma. J.Hepatol. 2009; 51: 315-321. Wona zvisingabvumirwe.
  79. Iwamoto, J., Matsumoto, H., uye Takeda, T. Kubudirira kwe menatetrenone (vitamini K2) inopesana neasina-vertebral nehudyu kutsemuka kune varwere vane chirwere chetsinga: meta-ongororo yeatatu akasarudzika, anotongwa miedzo. Kiriniki.Drug Investig. 2009; 29: 471-479. Wona zvisingabvumirwe.
  80. Crosier, MD, Peter, I., Booth, SL, Bennett, G., Dawson-Hughes, B., uye Ordovas, JM Association yekuteedzana misiyano muvhitamini K epoxide reductase uye gamma-glutamyl carboxylase majini ane biochemical zviyero zvevhitamini K chinzvimbo. J. Nutr. Sci. Vitaminol. (Tokyo) 2009; 55: 112-119. Wona zvisingabvumirwe.
  81. Iwamoto, J., Sato, Y., Takeda, T., uye Matsumoto, H. High-dose vhitamini K yekuwedzera inoderedza kutsemuka kwezviitiko mumashure meopaopaopaal vakadzi: ongororo yemabhuku. Nutrition Res. 2009; 29: 221-228. Wona zvisingabvumirwe.
  82. Shea, MK, O'Donnell, CJ, Hoffmann, U., Dallal, GE, Dawson-Hughes, B., Ordovas, JM, Mutengo, PA, Williamson, MK, uye Booth, SL Vitamin K kuwedzera uye kufambira mberi kwecoronary artery calcium mune varume vakuru nevakadzi. Ndiri. J. Clin. Nutr. 2009; 89: 1799-1807. Wona zvisingabvumirwe.
  83. Pfupiso kuvarwere. Vitamini K inobatsira vanhu vakatora warfarin yakawandisa here? Ann.Intern.Med. 3-3-2009; 150: I25. Wona zvisingabvumirwe.
  84. Kim, HS, Park, JW, Jang, JS, Kim, HJ, Shin, WG, Kim, KH, Lee, JH, Kim, HY, uye Jang, MK Kufungidzira kukosha kwealpha-fetoprotein uye mapuroteni anokonzerwa ne vitamini K kusavapo kana anopikisana-II muhepatitis B zvine chekuita nehutachiona hepatocellular carcinoma: anotarisira kudzidza. J.Clin.Gastroenterol. 2009; 43: 482-488. Wona zvisingabvumirwe.
  85. Inoue, T., Fujita, T., Kishimoto, H., Makino, T., Nakamura, T., Nakamura, T., Sato, T., uye Yamazaki, K. Randomized inodzorwa kudzidza pamusoro pekudzivirira kweosteoporotic fractures ( YOKUDZIDZA): chikamu IV kiriniki yekudzidza ye15-mg menatetrenone capsules. J. Bone Miner.Metab 2009; 27: 66-75. Wona zvisingabvumirwe.
  86. Cheung, AM, Tile, L., Lee, Y., Tomlinson, G., Hawker, G., Scher, J., Hu, H., Vieth, R., Thompson, L., Jamal, S., uye Josse, R. Vitamin K yekuwedzera mune postmenopausal vakadzi vane osteopenia (ECKO kuyedzwa): muyedzo unodzorwa kutongwa. PLoS.Med. 10-14-2008; 5: e196. Wona zvisingabvumirwe.
  87. Ishida, Y. [Vitamin K2]. Kliniki Calcium 2008; 18: 1476-1482. Wona zvisingabvumirwe.
  88. Hathaway, WE, Isarangkura, PB, Mahasandana, C., Jacobson, L., Pintadit, P., Pung-Amritt, P., uye Green, GM Kufananidza kwemuromo uye parenteral vhitamini K prophylaxis yekudzivirira kunonoka kwehemorrhagic chirwere che achangozvarwa. J.Pediatr. 1991; 119: 461-464. Wona zvisingabvumirwe.
  89. Iwamoto, J., Takeda, T., uye Sato, Y. Basa revhitamini K2 mukurapa postmenopausal osteoporosis. Curr.Drug Saf 2006; 1: 87-97. Wona zvisingabvumirwe.
  90. Marti-Carvajal, A. J., Cortes-Jofre, M., uye Marti-Pena, A. J. Vitamin K yekumusoro kwekubuda ropa mumatumbu muvarwere vane chirwere chechiropa. Cochrane.Database.Syst.Rev. 2008; CD004792. Wona zvisingabvumirwe.
  91. Drury, D., Grey, V. L., Ferland, G., Gundberg, C., uye Nyika, L. C. Kubudirira kwepamusoro phylloquinone mukugadzirisa kushomeka kwevhitamini K mucystic fibrosis. J.Cyst.Fibros. 2008; 7: 457-459. Wona zvisingabvumirwe.
  92. Macdonald, HM, McGuigan, FE, Lanham-New, SA, Fraser, WD, Ralston, SH, uye Reid, DM Vitamin K1 kudya kunosanganiswa nepamusoro pfupa remaminerari uye kuderedzwa kwepfupa resorption mune vekutanga postmenopausal vakadzi veScotland: hapana humbowo hwegen'a -kudyidzana kudyidzana neapolipoprotein E mapolymorphisms. Ndiri. J. Clin. Nutr. 2008; 87: 1513-1520. Wona zvisingabvumirwe.
  93. Nimptsch, K., Rohrmann, S., naLinseisen, J. Kudya kudya kwevhitamini K uye njodzi yekenza yeprostate muboka reHeidelberg reEuropean Prospective Investigation kuCancer and Nutrition (EPIC-Heidelberg). Ndiri. J. Clin. Nutr. 2008; 87: 985-992. Wona zvisingabvumirwe.
  94. Hotta, N., Ayada, M., Sato, K., Ishikawa, T., Okumura, A., Matsumoto, E., Ohashi, T., naKakumu, S. Mhedzisiro yevhitamin K2 pakudzokororwa kwevarwere vane hepatocellular carcinoma. Hepatogastroenterology 2007; 54: 2073-2077. Wona zvisingabvumirwe.
  95. Urquhart, D. S., Fitzpatrick, M., Cope, J., uye Jaffe, A. Vitamin K inorondedzera mapatani uye hutano hwekutarisa mapfupa muUK vana vane cystic fibrosis. J.Hum, Nutriti Kudya. 2007; 20: 605-610. Wona zvisingabvumirwe.
  96. Hosoi, T. [Kurapa kwepakutanga osteoporosis ine vhitamini K2]. Kliniki Calcium 2007; 17: 1727-1730. Wona zvisingabvumirwe.
  97. Jones, K. S., Bluck, L. J., Wang, L. Y., naCoward, W. A. ​​Nzira yakagadzika yesotopu yekuyera panguva imwe chete kwevhitamini K1 (phylloquinone) kinetics uye kutora. Eur.J.Clin.Nutr. 2008; 62: 1273-1281. Wona zvisingabvumirwe.
  98. Knapen, M.H, Schurgers, L. J., naVermeer, C. Vitamin K2 yekuwedzera inovandudza hudyu bone geometry uye mapfupa esimba mapfupa mune epashureopaopaal vakadzi. Osteoporos.Int. 2007; 18: 963-972. Wona zvisingabvumirwe.
  99. Maas, A.H, van der Schouw, Y. T., Beijerinck, D., Deurenberg, J. J., Mali, W. P., Grobbee, D. E., uye van der Graaf, Y. Vitamin K kudya uye kuverenga mumatope emvere. Maturita 3-20-2007; 56: 273-279. Wona zvisingabvumirwe.
  100. Dentali, F., Ageno, W., uye Crowther, M. Kurapa kwecoumarin-inosanganisirwa coagulopathy: yakarongeka ongororo uye yakarongedzwa kurapwa algorithms. J.Ruoko. Haemost. 2006; 4: 1853-1863. Wona zvisingabvumirwe.
  101. Liu, J., Wang, Q., Zhao, J.H, Chen, YH, naQin, G. L. Iyo yakabatana antenatal corticosteroids uye vhitamini K kurapa kwekudzivirira periventricular-intraventricular hemorrhage muvacheche vasati vasvika isingasviki makumi matatu nemashanu vhiki yekubata. J.Trop.Pediatr. 2006; 52: 355-359. Wona zvisingabvumirwe.
  102. Liu, J., Wang, Q., Gao, F., He, JW, uye Zhao, JH Maternal antatalatal administration yevhitamin K1 inoguma mukuwedzera zviitiko zvevitamin K-zvinoenderana necoagulation zvinhu muropa wembilical uye mukuderedza chiitiko chezviitiko. ye periventricular-intraventricular hemorrhage muvacheche vasati vasvika. J. Perinat. Yakagadziriswa. 2006; 34: 173-176. Wona zvisingabvumirwe.
  103. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., naOmmalley, P. G. Kurapa kwekuwandisa anticoagulation ne phytonadione (vitamini K): meta-ongororo. Arch.Intern.Med. 2-27-2006; 166: 391-397. Wona zvisingabvumirwe.
  104. Thijssen, H.H, Vervoort, L.M, Schurgers, L.J, naShearer, M. J. Menadione imetabolite yevhitamini yemuromo K. Br.J Nutr. 2006; 95: 260-266. Wona zvisingabvumirwe.
  105. Goldstein, JN, Thomas, SH, Frontiero, V., Joseph, A., Engel, C., Snider, R., Smith, EE, Greenberg, SM, naRosand, J. Nguva yekugadziriswa kwemazaya echando eplasma uye kururamisa nekukurumidza. yecoagulopathy muwarfarin-inosangana nepracerebral hemorrhage.Kurohwa 2006; 37: 151-155. Wona zvisingabvumirwe.
  106. Shetty, H.G., Backhouse, G., Bentley, D. P., naRoutledge, P. A. Kubudirira kudzoserwa kwewarfarin-inosimudzira yakawandisa anticoagulation ine yakaderera muyero vhitamini K1. Thromb.Haemost. 1-23-1992; 67: 13-15. Wona zvisingabvumirwe.
  107. Ageno, W., Garcia, D., Silingardi, M., Galli, M., uye Crowther, M. Kuedzwa kusinganzwisisike kuenzanisa 1 mg yevhitamini K yemuromo isina kurapwa mukutungamira kweiyo warfarin-inosanganisirwa coagulopathy mune varwere vane michina. mavharuvhu emwoyo. J.Am.Coll.Cardiol. 8-16-2005; 46: 732-733. Wona zvisingabvumirwe.
  108. Villines, T. C., Hatzigeorgiou, C., Feuerstein, I.M, O'malley, P. G., naTaylor, A. J. Vitamin K1 kudya uye coronary calcification. Tsinga. 2005; 16: 199-203. Wona zvisingabvumirwe.
  109. Yasaka, M., Sakata, T., Naritomi, H., uye Minematsu, K. Yakanakisa dhizaini yeprothrombin yakaoma kuisa pfungwa pakurapa kwakanyanya kwemuromo anticoagulation. Thromb.Res. 2005; 115: 455-459. Wona zvisingabvumirwe.
  110. Sato, Y., Honda, Y., Hayashida, N., Iwamoto, J., Kanoko, T., uye Satoh, K. Kushayikwa kweVitamin K uye osteopenia mumadzimai akwegura ane chirwere cheAlzheimer. Arch.Phys.Med.Rehabil. 2005; 86: 576-581. Wona zvisingabvumirwe.
  111. Sato, Y., Kanoko, T., Satoh, K., naIwamoto, J. Menatetrenone uye vhitamini D2 ine calcium zvinowedzera zvinodzivirira nonvertebral kuputsika mumadzimai akwegura ane chirwere cheAlzheimer. Bone 2005; 36: 61-68. Wona zvisingabvumirwe.
  112. Sasaki, N., Kusano, E., Takahashi, H., Ando, ​​Y., Yano, K., Tsuda, E., uye Asano, Y. Vitamin K2 inhibits glucocorticoid-indased bone kurasikirwa pamwe nekudzivirira kudzikiswa kwe osteoprotegerin (OPG). J. Bone Miner, Metab 2005; 23: 41-47. Wona zvisingabvumirwe.
  113. Kalkwarf, H. J., Khoury, J. C., Bean, J., naElliot, J. G. Vitamin K, kuwedzerwa kwemapfupa, uye bone mapfupa muvasikana. Ndiri. J. Clin. Nutr. 2004; 80: 1075-1080. Wona zvisingabvumirwe.
  114. Habu, D., Shiomi, S., Tamori, A., Takeda, T., Tanaka, T., Kubo, S., uye Nishiguchi, S. Basa revhitamini K2 mukukudziridzwa kwehepatocellular carcinoma muvakadzi vane hutachiona hwehutachiona. yechiropa. JAMA 7-21-2004; 292: 358-361. Wona zvisingabvumirwe.
  115. Dentali, F. naAgeno, W. manejimendi yecoumarin-inosanganisirwa coagulopathy murwere asiri kubuda ropa: ongororo yakarongeka. Haematologica 2004; 89: 857-862. Wona zvisingabvumirwe.
  116. Lubetsky, A., Hoffman, R., Zimlichman, R., Eldor, A., Zvi, J., Kostenko, V., naBrenner, B. Kubudirira nekuchengeteka kweprothrombin complex concentrate (Octaplex) yekukurumidza kuchinja muromo anticoagulation. Thromb.Res. 2004; 113: 371-378. Wona zvisingabvumirwe.
  117. Braam, L. A., Knapen, M.H, Geusens, P., Brouns, F., naVermeer, C. Zviitiko zvinokanganisa kurasikirwa kwemapfupa muvakadzi vanotsungirira vatambi: makore maviri ekutevera-ekudzidza. Ndiri. J. Mitambo Med. 2003; 31: 889-895. Wona zvisingabvumirwe.
  118. Lubetsky, A., Yonath, H., Olchovsky, D., Loebstein, R., Halkin, H., naEzra, D. Kufananidza kwemuromo vs intravenous phytonadione (vhitamini K1) mune varwere vane anticoagulation yakawandisa. kudzidza. Arch.Intern.Med. 11-10-2003; 163: 2469-2473. Wona zvisingabvumirwe.
  119. Braam, L. A., Knapen, M.H, Geusens, P., Brouns, F., Hamulyak, K., Gerichhausen, M. J., naVermeer, C. Vitamin K1 yekuwedzera inodzosera kurasikirwa kwemapfupa mune vakadzi ve postmenopausal pakati pemakore makumi mashanu nemakumi matanhatu ekuberekwa. Mhuka Int. 2003; 73: 21-26. Wona zvisingabvumirwe.
  120. Cornelissen, EA, Kollee, LA, De Abreu, RA, van Baal, JM, Motohara, K., Verbruggen, B., uye Monnens, LA Mhedzisiro yemuromo uye yepamuviri vhitamini K prophylaxis pane vhitamini K1, PIVKA-II, uye kugwamba zvinhu zviri mucheche anoyamwisa vacheche Arch. Dis. Mwana 1992; 67: 1250-1254. Wona zvisingabvumirwe.
  121. Malik, S., Udani, R.H, Bichile, S. K., Agrawal, R. M., Bahrainwala, A.T, naTilaye, S. Kuenzanisa kudzidza kwemuromo pamwe nejekiseni jekiseni vhitamini K mune neonates. Indian Pediatr. 1992; 29: 857-859. Wona zvisingabvumirwe.
  122. VIETTI, T. J., MURPHY, T. P., JAMES, J. A., uye PRITCHARD, J. A. Kucherechedzwa kwekushandiswa kweprophylactic kwevhitamini Kin mucheche achangozvarwa. J.Pediatr. 1960; 56: 343-346. Wona zvisingabvumirwe.
  123. Tabb, MM, Zuva, A., Zhou, C., Grun, F., Errandi, J., Romero, K., Pham, H., Inoue, S., Mallick, S., Lin, M., Forman , BM, uye Blumberg, B. Vitamin K2 mutemo we bone homeostasis inopindirana neiyo steroid uye xenobiotic receptor SXR. J Biol. Chem. 11-7-2003; 278: 43919-43927. Wona zvisingabvumirwe.
  124. Sorensen, B., Johansen, P., Nielsen, G. L., Sorensen, J. C., naIngerslev, J. Kudzoserwa kweInternational Normalized Ratio ine recombinant yakagadziriswa factor VII mukati mekutenderera kweropa kubuda ropa panguva yewarfarin thromboprophylaxis: kiriniki uye biochemical zvinhu. Ropa Coagul. Fibrinolysis 2003; 14: 469-477. Wona zvisingabvumirwe.
  125. Poli, D., Antonucci, E., Lombardi, A., Gensini, GF, Abbate, R., uye Prisco, D. Kuchengetedza uye kugona kweiyo yakaderera dosi yemumuromo vhitamini K1 manejimendi mune asymptomatic kunze-varwere pa warfarin kana acenocoumarol nekuwedzeredza. anticoagulation. Haematologica 2003; 88: 237-238. Wona zvisingabvumirwe.
  126. Yasaka, M., Sakata, T., Minematsu, K., naNaritomi, H. Kugadziriswa kweINR neprothrombin yakaoma kuisa pfungwa uye vhitamini K mune varwere vane warfarin inoenderana nekukanganiswa kweropa. Thromb.Res. 10-1-2002; 108: 25-30. Wona zvisingabvumirwe.
  127. Booth, SL, Broe, KE, Gagnon, DR, Tucker, KL, Hannan, MT, McLean, RR, Dawson-Hughes, B., Wilson, PW, Cupples, LA, uye Kiel, DP Vitamin K kudya uye bone mineral density mumadzimai nevarume. Ndiri. J. Clin. Nutr. 2003; 77: 512-516. Wona zvisingabvumirwe.
  128. Deveras, R. A. naKessler, C. M. Kudzoreredza warfarin-inokonzeresa anticoagulation ine recombinant yevanhu factor VIIa concentrate. Ann.Intern.Med. 12-3-2002; 137: 884-888. Wona zvisingabvumirwe.
  129. Riegert-Johnson, D.L uye Volcheck, G. W. Chiitiko cheanaphylaxis chinotevera intravenous phytonadione (vitamini K1): yemakore mashanu-ekudzokororazve. Ann. Allergy Chirwere Immunol. 2002; 89: 400-406. Wona zvisingabvumirwe.
  130. Kamwe, MA, Douketis, JD, Schnurr, T., Steidl, L., Mera, V., Ultori, C., Venco, A., naAgeno, W. Oral vhitamini K inoderedza huwandu hwepasi rose hwakaenzana nekukurumidza kupfuura pasika vhitamini K mukurapa warfarin-inosanganisirwa coagulopathy. Muedzo wakasarudzika, unodzorwa. Ann.Intern.Med. 8-20-2002; 137: 251-254. Wona zvisingabvumirwe.
  131. Ageno, W., Kwose, M., Steidl, L., Ultori, C., Mera, V., Dentali, F., Squizzato, A., Marchesi, C., uye Venco, A. Low dose yemuromo vhitamini K kudzoreredza acenocoumarol-inosimudzira coagulopathy: muyedzo unorongedzwa. Thromb.Haemost. 2002; 88: 48-51. Wona zvisingabvumirwe.
  132. Sato, Y., Honda, Y., Kaji, M., Asoh, T., Hosokawa, K., Kondo, I., uye Satoh, K. Kuvandudza osteoporosis ne menatetrenone mune vakwegura vakadzi veParkinson's chirwere chevarwere vane vhitamini D kushomeka. . Bone 2002; 31: 114-118. Wona zvisingabvumirwe.
  133. Olson, R. E., Chao, J., Graham, D., Bates, M. W., naLewis, J. H. Yese muviri phylloquinone uye mutero wayo muzvidzidzo zvevanhu pamatanho maviri evhitamini K kudya. Br. J. Nutriti. 2002; 87: 543-553. Wona zvisingabvumirwe.
  134. Andersen, P. naGodal, H. C. Kufanoona kushomeka kweanticoagulant zviitiko zvewarfarin nediki vhitamini K. Acta Med.Scand. 1975; 198: 269-270. Wona zvisingabvumirwe.
  135. Preston, F. E., Laidlaw, S. T., Sampson, B., uye Kicheni, S. Kukurumidza kuchinjisa kwemuromo anticoagulation newarfarin neprothrombin complex concentrate (Beriplex): kushanda pamwe nekuchengeteka muvarwere ve42. Br. J. Haematol. 2002; 116: 619-624. Wona zvisingabvumirwe.
  136. Evans, G., Luddington, R., naBaglin, T. Beriplex P / N inodzosera zvakakomba warfarin-inosimudzira overanticoagulation nekukasira uye zvakakwana muvarwere vanouya nekubuda kukuru kweropa. Br. J. Haematol. 2001; 115: 998-1001. Wona zvisingabvumirwe.
  137. Iwamoto, J., Takeda, T., uye Ichimura, S. Migumisiro ye menatetrenone pamapfupa emaminera emagetsi uye kuitika kwezvipembenene zvakaputsika mumashure memasopaopausal vakadzi vane osteoporosis: kuenzanisa nemigumisiro ye etidronate. J.Orthop.Sci. 2001; 6: 487-492. Wona zvisingabvumirwe.
  138. Sato, Y., Kaji, M., Tsuru, T., Satoh, K., naKondo, I. Kushayikwa kweVitamin K uye osteopenia muvhitamini D-vakadzi vakwegura vane chirwere cheParkinson. Arch.Phys.Med.Rehabil. 2002; 83: 86-91. Wona zvisingabvumirwe.
  139. Watson, H.G, Baglin, T., Laidlaw, S. L., Makris, M., uye Preston, F. E. Kufananidza kwekubudirira uye chiyero chekupindura kumuromo uye nemukati weVitamin K mukudzosera pamusoro-anticoagulation newarfarin. Br. J. Haematol. 2001; 115: 145-149. Wona zvisingabvumirwe.
  140. Kumar, D., Greer, F. R., Super, D.M, Suttie, J. W., naMoore, J. J. Vitamin K chinzvimbo chevacheche vasati vakurumidza: zvinoreva kurudziro yazvino. Pediatrics 2001; 108: 1117-1122. Wona zvisingabvumirwe.
  141. Nishiguchi, S., Shimoi, S., Kurooka, H., Tamori, A., Habu, D., Takeda, T., naKubo, S. Randomized mutyairi wendege kutongwa kwevhitamini K2 yekurasikirwa kwemapfupa nevarwere vane biliary cirrhosis. . J.Hepatol. 2001; 35: 543-545. Wona zvisingabvumirwe.
  142. Wilson, DC, Rashid, M., Durie, PR, Tsang, A., Kalnins, D., Andrew, M., Corey, M., Shin, J., Tullis, E., uye Pencharz, PB Kurapa kwevhitamini. K kushomeka kwecystic fibrosis: Kubudirira kwevhitamini yemafuta yezuva nezuva yakasanganiswa nemafuta. J.Pediatr. 2001; 138: 851-855. Wona zvisingabvumirwe.
  143. Pendry, K., Bhavnani, M., uye Shwe, K. Kushandiswa kwemuromo vhitamini K yekudzosera pamusoro pe-warfarinization. Br. J. Haematol. 2001; 113: 839-840. Wona zvisingabvumirwe.
  144. Fondevila, C. G., Grosso, S.H, Santarelli, M.T, uye Pinto, M. D. Kudzoreredza kwakanyanya kwemuromo anticoagulation ine yakaderera muromo wevhitamini K1 uchienzaniswa neacenocoumarine kumisa. Anotarisira, akasarudzika, akavhurika kudzidza. Ropa Coagul. Fibrinolysis 2001; 12: 9-16. Wona zvisingabvumirwe.
  145. Cartmill, M., Dolan, G., Byrne, J. L., uye Byrne, P. O. Prothrombin yakaoma kuisa pfungwa pamuromo anticoagulant inodzosera mukukurumidzira kweeurosurgical. Br. J. Neurosurg. 2000; 14: 458-461. Wona zvisingabvumirwe.
  146. Iwamoto, J., Takeda, T., uye Ichimura, S. Mhedzisiro yekubatanidzwa kwevhitamini D3 uye vhitamini K2 pamapfupa emaminetsi emagetsi eiyo lumbar musana mune postmenopausal vakadzi vane osteoporosis. J.Orthop.Sci. 2000; 5: 546-551. Wona zvisingabvumirwe.
  147. Zvakadaro, MA, Julian, J., McCarty, D., Douketis, J., Kovacs, M., Biagoni, L., Schnurr, T., McGinnis, J., Gent, M., Hirsh, J., uye Ginsberg, J. Kurapa kwewarfarin-inosanganisirwa coagulopathy nemukanwa vhitamini K: kuyedzwa kusarongeka. Lancet 11-4-2000; 356: 1551-1553. Wona zvisingabvumirwe.
  148. Puckett, R. M. naOffringa, M. Prophylactic vhitamini K yevhitamini K inoshaya kubuda ropa mumaonates. Cochrane.Database.Syst.Rev. 2000; CD002776. Wona zvisingabvumirwe.
  149. Patel, R. J., Witt, D. M., Saseen, J. J., Tillman, D. J., naWilkinson, D. S. Randomized, placebo-inodzorwa kutongwa kwepamuromo phytonadione yekuwedzeredza anticoagulation. Pharmacotherapy 2000; 20: 1159-1166. Wona zvisingabvumirwe.
  150. Hung, A., Singh, S., uye Tait, R. C. Chingafungidzirwa chakasarudzika kudzidza kuti uone huwandu hwakakwana hwevhitamini K inopinza mukuchinja kwe-over-warfarinization. Br. J. Haematol. 2000; 109: 537-539. Wona zvisingabvumirwe.
  151. Hylek, E. M., Chang, Y. C., Skates, S. J., Hughes, R. A., uye Singer, D. E. Inotarisirwa kuongorora mhedzisiro yevarwere vemaamburera vane yakawandisa warfarin anticoagulation. Arch.Intern.Med. 6-12-2000; 160: 1612-1617. Wona zvisingabvumirwe.
  152. Brophy, M.T., Fiore, L. D., naDeykin, D. Low-Dose Vitamin K Therapy muVazhinji Varwere Vanogadziriswa: A Dose-Kutsvaga Kudzidza. J.Thomberi. 1997; 4: 289-292. Wona zvisingabvumirwe.
  153. Raj, G., Kumar, R., uye McKinney, W. P. Nguva yenguva yekudzosera anticoagulant mhedzisiro yewarfarin neinopinda uye subcutaneous phytonadione. Arch.Intern.Med. 12-13-1999; 159: 2721-2724. Wona zvisingabvumirwe.
  154. Byrd, D., Stephens, M. A., Hamann, G.L, naDorko, C. Subcutaneous phytonadione yekudzosera kukwirisa-kunokonzerwa newarfarin yeInternational Normalized Ratio. Ndiri. J. Health Syst. 11-15-1999; 56: 2312-2315. Wona zvisingabvumirwe.
  155. Boulis, N. M., Bobek, M. P., Schmaier, A., naHoff, J. T. Kushandisa kwechinhu IX chakaomeswa muharfarin inoenderana nekukanganisa kubuda kweropa. Neurosurgery 1999; 45: 1113-1118. Wona zvisingabvumirwe.
  156. Rashid, M., Durie, P., Andrew, M., Kalnins, D., Shin, J., Corey, M., Tullis, E., uye Pencharz, P. B. Kuwandisa kwevhitamini K kushomeka mucystic fibrosis. Ndiri. J. Clin. Nutr. 1999; 70: 378-382. Wona zvisingabvumirwe.
  157. Booth, S. L., O'Brien-Morse, M. E., Dallal, G. E., Davidson, K. W., naGundberg, C. M. Mhinduro yevhitamini K chinzvimbo kune akasiyana mabviro uye manyuko ezvekudya zvine phylloquinone: kuenzanisa kwevakuru uye vakuru vakuru. Ndiri. J. Clin. Nutr. 1999; 70: 368-377. Wona zvisingabvumirwe.
  158. Somekawa, Y., Chigughi, M., Harada, M., uye Ishibashi, T. Kushandisa vhitamini K2 (menatetrenone) uye 1,25-dihydroxyvitamin D3 mukudzivirira kurasikirwa kwepfupa kunokonzerwa neleuprolide. J.Clin.Endocrinol.Metab 1999; 84: 2700-2704. Wona zvisingabvumirwe.
  159. Sato, Y., Tsuru, T., Oizumi, K., naKaji, M. Vitamin K kushomeka uye osteopenia mukushandisa zvisina kukanganiswa mitezo yevhitamini D-inoshaya vakwegura sitiroko varwere. Ndiri.J.Phys.Med.Rehabil. 1999; 78: 317-322. Wona zvisingabvumirwe.
  160. Nee, R., Doppenschmidt, D., Donovan, D.J, naAndrews, T. C. Inopinza inopesana necitaminaneous vhitamini K1 mukudzora yakawandisa anticoagulation yemuromo. Ndiri. J. Cardiol. 1-15-1999; 83: 286-287. Wona zvisingabvumirwe.
  161. Penning-van Beest, F. J., Rosendaal, F. R., Grobbee, D. E., van, Meegen E., uye Stricker, B. H. Course yeInternational Normalized Ratio mukupindura kwemuromo vhitamini K1 mune varwere vanowedzeredzwa ne phenprocoumon. Br. J. Haematol. 1999; 104: 241-245. Wona zvisingabvumirwe.
  162. Bolton-Smith, C., McMurdo, ME, Paterson, CR, Mole, PA, Harvey, JM, Fenton, ST, Prynne, CJ, Mishra, GD, naShearer, MJ Makore maviri-akasarudzika akaedzwa anotongwa eitamin K1 (phylloquinone ) uye vhitamini D3 pamwe calcium pahutano hwemapfupa evakadzi vakuru. J. Bhonzo Miner. 2007; 22: 509-519. Wona zvisingabvumirwe.
  163. Ishida, Y. naKawai, S. Kuenzanisa kushanda kwehomoni kutsiva kurapa, etidronate, calcitonin, alfacalcidol, uye vhitamini K mune postmenopausal vakadzi vane osteoporosis: Iyo Yamaguchi Osteoporosis Kudzivirira Kudzidza. Ndiri. J. Med. 10-15-2004; 117: 549-555. Wona zvisingabvumirwe.
  164. Booth SL, Golly Ini, Sacheck JM, et al. Mhedzisiro yevhitamin E yekuwedzera pane vhitamini K chinzvimbo muvakuru vane zvakajairika coagulation mamiriro. Ndiri J Kliniki Nutriti. 2004; 80: 143-8. Wona zvisingabvumirwe.
  165. Wostmann BS, Knight PL. Kupesana pakati pevhitamini A uye K mune germfree rat. J Nutriti. 1965; 87: 155-60. Wona zvisingabvumirwe.
  166. Kim JS, Nafziger AN, Gaedigk A, et al. Migumisiro yevhitamini K yemuromo paS- uye R-warfarin pharmacokinetics uye pharmacodynamics: yakachengetedzwa chengetedzo yewarfarin seye CYP2C9 probe. J Clin Pharmacol. 2001 Jul; 41: 715-22. Wona zvisingabvumirwe.
  167. Kudya kwevhitamini K kutungamira: zano rinoshanda rekudzora kudzora kwemuromo anticoagulation? Nutriti Rev. 2010; 68: 178-81. Wona zvisingabvumirwe.
  168. Kumwe MA, Ageno W, Garcia D, et al. Oral vhitamini K maringe ne placebo kururamisa yakawandisa anticoagulation muvarwere vanogamuchira warfarin: kuyedzwa kusarongeka. Ann Mukati Med. 2009; 150: 293-300. Wona zvisingabvumirwe.
  169. Jagannath VA, Fedorowicz Z, Thaker V, Chang AB. Vitamin K yekuwedzera yecystic fibrosis. Cochrane Database Syst Rev. 2011;: CD008482. Wona zvisingabvumirwe.
  170. Miesner AR, Sullivan TS. Yakakwidziridzwa yepasirese yakajairwa chiyero kubva kune vhitamini K yekuwedzera kumisa. Ann Pharmacother 2011; 45: e2. Wona zvisingabvumirwe.
  171. Ansell J, Hirsh J, Hylek E, et al. Pharmacology uye manejimendi evhithamini K vanopikisa: American College yeChest Vanachiremba Uchapupu-Hwakavakirwa Pakiriniki Dzidzira Maitiro (8th Edition). Chifuva 2008; 133: 160S-98S. Wona zvisingabvumirwe.
  172. Rombouts EK, Rosendaal FR. Van Der Meer FJ. Mazuva ese vitamini K yekuwedzera inovandudza anticoagulant kugadzikana. J Thromb Haemost 2007; 5: 2043-8. Wona zvisingabvumirwe.
  173. Reese AM, Farnett LE, Lyons RM, et al. Low-dose vhitamini K kuwedzera anticoagulation kudzora. Pharmacotherapy 2005; 25: 1746-51. Wona zvisingabvumirwe.
  174. Sconce E, Avery P, Wynne H, Kamali F. Vitamin K yekuwedzera inogona kuvandudza kugadzikana kweanticoagulation yevarwere vane kusanzwisisika kusiana mukupindura warfarin. Ropa 2007; 109: 2419-23. Wona zvisingabvumirwe.
  175. Kurnik D, Lobestein R, Rabinovitz H, uye al. Over-the-counter vhitamini K1-ine multivitamin zvinowedzera zvinokanganisa warfarin anticoagulation muvitamini K1-vakapera varwere. Thromb Haemost 2004; 92: 1018-24. Wona zvisingabvumirwe.
  176. Sconce E, Khan T, Mason J, et al. Varwere vane kusagadzikana kudzora vane hurombo hwekudya kudya kwevhitamini K zvichienzaniswa nevarwere vane kugadzikana kudzora anticoagulation. Thromb Haemost 2005; 93: 872-5. Wona zvisingabvumirwe.
  177. Tamura T, Morgan SL, Takimoto H. Vitamin K uye kudzivirira kwekuputsika (tsamba uye mhinduro). Arch Int Med 2007; 167: 94-5. Wona zvisingabvumirwe.
  178. Beulens JW, Bhoti ML, Atsma F, et al. Kudya kwakanyanya menaquinone kudya kunosanganisirwa nekuderedza coronary calcification. Atherosclerosis 2009; 203: 489-93. Wona zvisingabvumirwe.
  179. Booth SL, Dallal G, Shea MK, et al. Mhedzisiro yevhitamin K yekuwedzera pane kurasikirwa kwepfupa muvarume nevakadzi vakura. J Clin Endocrinol Metab 2008; 93: 1217-23. Wona zvisingabvumirwe.
  180. Schurgers LJ, Dissel PE, Spronk HM, et al. Basa revhitamini K uye vhitamini K-anoenderana nemapuroteni muvascular calcification. Z Kardiol 2001; 90 (mutsigiri 3): 57-63. Wona zvisingabvumirwe.
  181. Geleijnse JM, Vermeer C, Grobbee DE, uye al. Kudya kwekudya kwemenaquinone inosanganisirwa nenjodzi yakadzikira yechirwere chemoyo checoronary: Chidzidzo cheRotterdam. J Nutriti 2004; 134: 3100-5. Wona zvisingabvumirwe.
  182. Al-Terkait F, Charalambous H.Seagulopathy yakadzika yechipiri kusvika kune vhitamini K kushomeka kwemurwere ane diki-ura resection uye gomarara rekwere. Lancet Oncol 2006; 7: 188. Wona zvisingabvumirwe.
  183. Yoshikawa H, Yamazaki S, Watanabe T, Abe T. Vitamin K inoshaya muvana vakaremara zvakanyanya. J Mwana Neurol. 2003; 18: 93-7. Wona zvisingabvumirwe.
  184. Schoon EJ, Muller MC, Vermeer C, et al. Yakaderera serum uye pfupa vhitamini K chinzvimbo mune varwere vane kwenguva refu Crohn's chirwere: chimwe pathogenetic chinokonzera osteoporosis muCrohn's chirwere? Gut 2001; 48: 473-7. Wona zvisingabvumirwe.
  185. Szulc P, Meunier PJ. Iko kushomeka kwevhitamini K chinhu chinokonzera osteoporosis muchirwere cheCrohn? Lancet 2001; 357: 1995-6. Wona zvisingabvumirwe.
  186. Duggan P, O'Brien M, Kiely M, uye al. Vitamin K chimiro mune varwere vane chirwere cheCrohn uye hukama kune bone pfupa. Am J Gastroenterol 2004; 99: 2178-85. Wona zvisingabvumirwe.
  187. Cockayne S, Adamson J, Lanham-Nyowani S, et al. Vitamin K uye kudzivirira kwekuputsika. kuongororwa kwakarongeka uye meta-kuongororwa kwemiedzo yakasarudzika. Arch Mukati Med 2006; 166: 1256-61. Wona zvisingabvumirwe.
  188. Rejnmark L, Vestergaard P, Charles P, et al. Hapana mhedzisiro yevhitamini K inodya pamapfupa emamineral density uye kutsemuka kwengozi mumadzimai eperimenopausal Osteoporos Int 2006; 17: 1122-32. Wona zvisingabvumirwe.
  189. Robert D, Jorgetti V, Leclercq M, et al. Vitamini K yakawandisa inokanganisa ectopic calcization muhemodialysis varwere? Kiriniki Nephrol 1985; 24: 300-4. Wona zvisingabvumirwe.
  190. Tam DA Jr, Myer EC. Vitamin K-inotenderera coagulopathy mumwana ari kuwana anticonvulsant kurapwa. J Mwana Neurol 1996; 11: 244-6. Wona zvisingabvumirwe.
  191. Keith DA, Gundberg CM, Japour A, et al. Vitamin K-anoenderana nemapuroteni uye anticonvulsant mishonga. Clin Pharmacol Ther 1983; 34: 529-32. Wona zvisingabvumirwe.
  192. Thorp JA, Gaston L, Caspers DR, Pal ML. Pfungwa dzazvino nemakakava mukushandiswa kwevhitamini K. Zvinodhaka 1995; 49: 376-87. Wona zvisingabvumirwe.
  193. Bleyer WA, Skinner AL. Inouraya neonatal hemorrhage mushure mamai anticonvulsant kurapa. JAMA 1976; 235: 626-7.
  194. Renzulli P, Tuchschmid P, Eich G, uye al. Yekutanga vhitamini K kushomeka kwekubuda ropa mushure mekuberekwa kwaamai phenobarbital kudya: manejimendi yekusagadzikana kukuru kweropa nekupindira kushoma kwekuvhiya Eur J Pediatr 1998; 157: 663-5. Wona zvisingabvumirwe.
  195. Cornelissen M, Vanochengetedza-Theunissen R, Kollee L, et al. Kuwedzeredza vhitamini K mune vakadzi vane nhumbu vanowana anticonvulsant kurapwa kunodzivirira neonatal vhitamini K kushomeka. Am J Obstet Gynecol 1993; 168: 884-8. Wona zvisingabvumirwe.
  196. Cornelissen M, Vanochengetedza-Theunissen R, Kollee L, et al. Kuwedzera kwezviitiko zvekuzvarwa kwevhitamin K kushomeka kunokonzerwa neanamai anticonvulsant kurapwa. Am J Obstet Gynecol 1993; 168: 923-8. Wona zvisingabvumirwe.
  197. MacWalter RS, Fraser HW, Armstrong KM. Orlistat inowedzera warfarin mhedzisiro. Ann Pharmacother 2003; 37: 510-2. Wona zvisingabvumirwe.
  198. Vroonhof K, van Rijn HJ, van Hattum J. Vitamin K kushomeka uye kubuda ropa mushure mekushandisa kwenguva refu cholestyramine. Neth J Med 2003; 61: 19-21. Wona zvisingabvumirwe.
  199. Van Steenbergen W, Vermylen J. Reversible hypoprothrombinemia mune murwere ane primary biliary cirrhosis inorapwa ne rifampicin. Am J Gastroenterol 1995; 90: 1526-8. Wona zvisingabvumirwe.
  200. Kobayashi K, Haruta T, Maeda H, et al. Cerebral hemorrhage inosanganisirwa nekushomeka kwevhitamini K mu congenital tuberculosis inorapwa ne isoniazid uye rifampin. Pediatr Infect Dis J 2002; 21: 1088-90. Wona zvisingabvumirwe.
  201. Sattler FR, Weitekamp MR, Ballard JO. Zvichida kubuda ropa neiyo nyowani beta-lactam mishonga inorwisa mabhakitiriya. Ann Mukati Med 1986; 105: 924-31. Wona zvisingabvumirwe.
  202. Bhat RV, Deshmukh CT. Chidzidzo cheVitamin K chinzvimbo muvana pane yakareba mishonga inorwisa mabhakitiriya. Indian Pediatr 2003; 40: 36-40. Wona zvisingabvumirwe.
  203. Hooper CA, Haney BB, Dombo HH. Kubuda ropa mudumbu nekuda kwekushomeka kwevhitamini K mune varwere pane parenteral cefamandole. Lancet 1980; 1: 39-40. Wona zvisingabvumirwe.
  204. Haubenstock A, Schmidt P, Zazgornik J, Balcke P, Kopsa H. Hypoprothrombobinaemic kubuda ropa kwakabatana ne ceftriaxone. Lancet 1983; 1: 1215-6. Wona zvisingabvumirwe.
  205. Kudzora P, Zheng ZB. Pane mashandiro eiyo anticlotting chiito che vitamini E quinone. Proc Natl Acad Sci U S A 1995; 92: 8171-5. Wona zvisingabvumirwe.
  206. Bolton-Smith C, Mutengo RJ, Fenton ST, et al. Kuumbwa kwechinguva chidiki cheUK database yeiyo phylloquinone (vhitamini K1) zvemukati zvezvikafu. Br J Nutriti 2000; 83: 389-99. Wona zvisingabvumirwe.
  207. Davies VA, Rothberg AD, Argent AC, Atkinson PM, Staub H, Pienaar NL. Precursor prothrombin chinzvimbo muvarwere vanogamuchira anticonvulsant zvinodhaka. Lancet 1985; 1: 126-8. Wona zvisingabvumirwe.
  208. Davidson MH, Hauptman J, DiGirolamo M, uye al. Kurema kwehuremu uye njodzi yekudzikisira muzvinhu zvakawandisa zvakarapwa kwemakore maviri neorlistat. JAMA 1999; 281: 235-42. Wona zvisingabvumirwe.
  209. Schade RWB, van't Laar A, Majoor CLH, Jansen AP. Chidzidzo chekuenzanisa chemhedzisiro yecholestyramine uye neomycin pakurapa kworudzi rwechipiri hyperlipoproteinemia. Acta Med Scand 1976; 199: 175-80 .. Wona zvisiri izvo.
  210. Bendich A, Langseth L. Kuchengetedzwa kwevhitamini A. Am J Kemikari Nutriti 1989; 49: 358-71 .. Wona zvisingabvumirwe.
  211. McDuffie JR, Calis KA, Booth SL, uye al. Mhedzisiro yeorlistat pamafuta-akanyungudika mavitamini mune vakawandisa kuyaruka. Pharmacotherapy 2002; 22: 814-22 .. Wona zvisiri izvo.
  212. Goldin BR, Lichtenstein AH, Gorbach SL. Nutritional and metabolic majukumu emumatumbo maruva. Mune: Shils ME, Olson JA, Shike M, eds. Chazvino Chikafu muhutano uye Zvirwere, 8th ed. Malvern, PA: Lea & Febiger, 1994.
  213. Kudya uye Kudya kweBhodi, Sisitimu yeMishonga. Dhijitari Referensi Inotora Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Mhangura, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, uye Zinc. Washington, DC: National Academy Press, 2002. Inowanikwa pa: www.nap.edu/books/0309072794/html/.
  214. Jamal SA, Browner WS, Bauer DC, Cummings SR. Warfarin kushandisa uye njodzi ye osteoporosis mune vakadzi vakura. Kudzidza kweOsteoporotic Fractures Research Group. Ann Mukati Med 1998; 128: 829-832. Wona zvisingabvumirwe.
  215. Mucheki MJ. Basa revhitamini D uye K mune bone hutano uye osteoporosis kudzivirira. Proc Nutr Sci 1997; 56: 915-37. Wona zvisingabvumirwe.
  216. Tamatani M, Morimoto S, Nakajima M, et al. Kuderedza kutenderera kwehuwandu hwevhitamini K uye 25-hydroxyvitamin D mune vakwegura vane osteopenic. Metabolism 1998; 47: 195-9. Wona zvisingabvumirwe.
  217. Weber P. manejimendi yemaosteoporosis: pane basa here kune vhitamini K? Int J Vitam Nutriti Res 1997; 67: 350-356. Wona zvisingabvumirwe.
  218. Mutengo PA. Vitamin K zvinovaka muviri uye postmenopausal osteoporosis. J Clin Invest 1993; 91: 1268. Wona zvisingabvumirwe.
  219. Yonemura K, Kimura M, Miyaji T, Hishida A. Ipfupi-yenguva mhedzisiro mhedzisiro yevhitamini K manejimendi pane prednisolone-inokonzeresa kurasikirwa kwefupa remaminera mashoma mune varwere vane chisingaperi glomerulonephritis. Calcif Tissue Int 2000; 66: 123-8. Wona zvisingabvumirwe.
  220. Knapen MH, Hamulyak K, Vermeer C. Mhedzisiro yevhitamini K yekuwedzera pakutenderera osteocalcin (bone Gla protein) uye weti calcium excretion. Ann Mukati Med 1989; 111: 1001-5. Wona zvisingabvumirwe.
  221. Douglas AS, Robins SP, Hutchison JD, et al. Carboxylation ye osteocalcin mumashure-menopausal osteoporotic vakadzi vanotevera vhitamini K uye D yekuwedzera. Pfupa 1995; 17: 15-20. Wona zvisingabvumirwe.
  222. Booth SL, Tucker KL, Chen H, uye al. Kudya kwevhitamini K inodyiwa inosanganiswa nekutsemuka kwehudyu asi kwete nefupa remaminerari muvachembera varume nevakadzi. Am J Kliniki Nutriti 2000; 71: 1201-8. Wona zvisingabvumirwe.
  223. Heck AM, DeWitt BA, Lukes AL. Kugona kudyidzana pakati peimwe nzira dzokurapa uye warfarin. Am J Hutano Syst Pharm 2000; 57: 1221-7. Wona zvisingabvumirwe.
  224. Becker GL. Mhosva inopesana nemafuta emafuta Am J Kugaya Dis 1952; 19: 344-8. Wona zvisingabvumirwe.
  225. Schwarz KB, Goldstein PD, Witztum JL, et al. Mafuta-akanyungudika mavhitamini anowanikwa mu hypercholestrolemic vana vanorapwa necolestipol. Pediatrics 1980; 65: 243-50. Wona zvisingabvumirwe.
  226. Knodel LC, Talbert RL. Migumisiro yakaipa ye hypolipidaemic zvinodhaka. Med Toxicol 1987; 2: 10-32. Wona zvisingabvumirwe.
  227. Kumadokero RJ, Lloyd JK. Mhedzisiro ye cholestyramine pane kuyamwa kwemukati. Gut 1975; 16: 93-8. Wona zvisingabvumirwe.
  228. Conly JM, Stein K, Worobetz L, Rutledge-Harding S. Mupiro wevhitamini K2 (menaquinones) unoburitswa nemudumbu microflora kune zvinodiwa nevanhu zvehutano zvevhitamini K. Am J Gastroenterol 1994; 89: 915-23. Wona zvisingabvumirwe.
  229. Chikomo MJ. Matumbu emukati uye endo nativeous vitamini synthesis. Eur J Kanzera Prev 1997; 6: S43-5. Wona zvisingabvumirwe.
  230. Spigset O. Yakaderedzwa mhedzisiro yewarfarin inokonzerwa neubidecarenone. Lancet 1994; 334: 1372-3. Wona zvisingabvumirwe.
  231. Roche, Inc. Xenical pasuru yekuisa. Nutley, NJ. Chivabvu 1999.
  232. Feskanich D, Weber P, Willett WC, et al. Vitamin K yekudya uye chiuno kutsemuka mune vakadzi: anotarisira kudzidza. Am J Kliniki Nutriti 1999; 69: 74-9. Wona zvisingabvumirwe.
  233. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman naGillman's Iyo Pharmacological Hwaro hweTherapeutics, 9th ed. New York, NY: McGraw-Chikomo, 1996.
  234. Wechidiki DS. Mhedzisiro yeMirimo paKiriniki YeLabhoritari Kuedza 4th ed. Washington: AACC Press, 1995.
  235. Corrigan JJ Jr, Marcus FI. Coagulopathy inosangana ne vitamini E kumedza. JAMA 1974; 230: 1300-1. Wona zvisingabvumirwe.
  236. Shearer MJ, Bach A, Kohlmeier M. Chemistry, manyuko ezvehutano, kugovaniswa kwetishu uye metabolism yemavitamini K ane chirevo chakanangana nehutano hwepfupa. J Nutriti 1996; 126: 1181S-6S. Wona zvisingabvumirwe.
  237. Kanai T, Takagi T, Masuhiro K, et al. Serum vhitamini K mwero uye mapfupa emamineral density mune epashure-menopausal vakadzi. Int J Gynaecol Chibvumirano 1997; 56: 25-30. Wona zvisingabvumirwe.
  238. Hodges SJ, Akesson K, Vergnaud P, et al. Kutenderera mazinga evitamini K1 uye K2 zvakadzikira mumadzimai akwegura ane kutsemuka kwechiuno. J Bone Miner Res 1993; 8: 1241-5. Wona zvisingabvumirwe.
  239. Hart JP, Shearer MJ, Klenerman L, et al. Electrochemical kuona kweakaora mwoyo anotenderera ehuwandu hwevhitamini K1 mu osteoporosis. J Clin Endocrinol Metab 1985; 60: 1268-9. Wona zvisingabvumirwe.
  240. Bitensky L, Hart JP, Catterall A, uye al. Kuparadzira mavitamini K mazinga evarwere vane mafupa. J Bone Joint Kuvhiya Br 1988; 70: 663-4. Wona zvisingabvumirwe.
  241. Nagasawa Y, Fujii M, Kajimoto Y, et al. Vitamin K2 uye serum cholesterol mune varwere pane inoenderera amburenzi peritoneal dialysis. Lancet 1998; 351: 724. Wona zvisingabvumirwe.
  242. Iwamoto I, Kosha S, Noguchi S, et al. Yekureba kudzidza kwekuita kwevhitamini K2 pamapfupa emamineral density mune vakadzi ve postmenopausal chidzidzo chekuenzanisa ne vitamin D3 uye estrogen-progestin therapy. Maturitas 1999; 31: 161-4. Wona zvisingabvumirwe.
  243. Vermeer C, Schurgers LJ. Kuongorora kwakazara kwevhitamini K uye vhitamini K vanopikisa. Hematol Oncol Kliniki North Am 2000; 14: 339-53. Wona zvisingabvumirwe.
  244. Vermeer C, Gijsbers BL, Craciun AM, uye al. Mhedzisiro yevhitamin K pane bone bone uye bone metabolism. J Nutriti 1996; 126: 1187S-91S. Wona zvisingabvumirwe.
  245. Olson RE. Osteoporosis uye vhitamini K kudya. Am J Kliniki Nutriti 2000; 71: 1031-2. Wona zvisingabvumirwe.
  246. Shiraki M, Shiraki Y, Aoki C, Miura M. Vitamin K2 (menatetrenone) zvinobudirira zvinodzivirira kutsemuka uye inotsigira lumbar bone mineral density muosteoporosis. J Bone Miner Res 2000; 15: 515-21. Wona zvisingabvumirwe.
  247. Jie KG, Bots ML, Vermeer C, et al. Vitamin K chinzvimbo uye mapfupa mashoma mune vakadzi vane uye vasina aortic atherosclerosis: chidzidzo chevanhu. Calcif Tissue Int 1996; 59: 352-6. Wona zvisingabvumirwe.
  248. Caraballo PJ, Heit JA, Atkinson EJ, et al. Kushandiswa kwenguva refu kwemuromo anticoagulants uye njodzi yekutyoka. Arch Mukati Med 1999; 159: 1750-6. Wona zvisingabvumirwe.
  249. Matsunaga S, Ito H, Sakou T. Mhedzisiro yevhitamin K uye D yekuwedzera pane ovariectomy-inokonzeresa kurasikirwa kwefupa. Calcif Tissue Int 1999; 65: 285-9. Wona zvisingabvumirwe.
  250. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Kuongorora uye Kurapa Kwevanhu Kutyisa. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  251. McEvoy GK, rakanyorwa. AHFS Ruzivo rweMishonga. Bethesda, MD: American Society yeHutano-Sisitimu Varapi, 1998.
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