Munyori: Gregory Harris
Zuva Rekusika: 8 Kubvumbi 2021
Gadziridza Zuva: 19 Mbudzi 2024
Anonim
Linezolid (Oxazolidinone Antibiotic) - Mechanism of Action, Indications, and Side Effects
Vhidhiyo: Linezolid (Oxazolidinone Antibiotic) - Mechanism of Action, Indications, and Side Effects

Zvemukati

Linezolid inoshandiswa kurapa hutachiona, kusanganisira mabayo, uye hutachiona hweganda. Linezolid iri mukirasi yemabhakitiriya anonzi oxazolidinones. Inoshanda nekumisa kukura kwehutachiona.

Mishonga inorwisa mabhakitiriya senge linezolid haishande nekuda kwemafuru, dzihwa, uye zvimwe hutachiona hwehutachiona. Kushandisa mishonga inorwisa mabhakitiriya painenge isingadiwe kunowedzera mukana wako wekutapukirwa nehutachiona hunoramba kurapwa kwemaantibayoti.

Linezolid inouya sehwendefa uye kumiswa kwemuromo (mvura) kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kaviri pazuva (maawa gumi nemaviri) kwemazuva gumi kusvika makumi maviri nemasere. Vana vane makore gumi nerimwe ekuberekwa uye vadiki vanowanzotora linezolid pamwe kana pasina chikafu kaviri kana katatu pazuva (maawa masere kusvika gumi nemaviri) kwemazuva gumi kusvika makumi maviri nemasere. Kureba kwekurapa kwako kunoenderana nerudzi rwehutachiona hwauinazvo. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora linezolid chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Usati washandisa kusimiswa kwemuromo, zvinyoronyoro usanganise nekutenderedza bhodhoro katatu kana kashanu Usazunungusa kusimiswa.

Tora linezolid kusvikira wapedza mushonga, kunyangwe kana uchinzwa zvirinani. Usarega kutora linezolid usina kutaura nachiremba wako. Kana iwe ukarega kutora linezolid nekukurumidza kana kana iwe ukasvetuka madosi, hutachiona hwako hunogona kusarapwa zvakakwana uye mabhakitiriya anogona kupokana nemishonga inorwisa mabhakitiriya.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora linezolid,

  • udza chiremba wako uye wemishonga kana uri weergoria kune linezolid, chero mimwe mishonga, kana chero chinhu chinogadzirwa mune linezolid chigadzirwa chawakatemerwa. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako kana uri kutora mishonga inotevera kana kuti warega kuinwa mukati memavhiki maviri apfuura: isocarboxazid (Marplan) phenelzine (Nardil). rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), uye tranylcypromine (Parnate). Chiremba wako angangokuudza kuti usatore linezolid kana uri kutora imwe kana yakawanda yemishonga iyi, kana kuti wakavatora mukati memavhiki maviri apfuura.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero einotevera: epinephrine (EpiPen); meperidine (Demerol); mishonga yemigraine yakadai sa almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, muTreximet), uye zolmitriptan (Zomig); phenylpropanolamine (haichawanikwi muUS); uye pseudoephedrine (Yakasvibiswa; mune yakawanda inotonhorera kana mishonga inoderedza mishonga). Uyewo udza chiremba wako kana uri kutora mishonga inotevera kana kuti wakarega kuinwa mukati memavhiki maviri apfuura: bupropion (Aplenzin, Wellbutrin, Zyban, vamwe); buspirone; inosarudza serotonin reuptake inhibitors (SSRIs) senge citalopram (Celexa), escitalopram (Lexapro), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), sertraline (Zoloft), uye vilazodone (Vilbyrd); serotonin norepinephrine reuptake inhibitors (SNRIs) senge desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), uye venlafaxine (Effexor); uye tricyclic antidepressants senge amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), uye trimontramine. Uyezve udza chiremba wako kana uri kutora fluoxetine (Prozac, Sarafem, Selfemra, muSymbyax), kana kuti warega kuitora mukati memavhiki mashanu apfuura. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana ne linezolid, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
  • udza chiremba wako kana iwe uine chirwere chisingaperi (chisingagumi), kana kana iwe kana wakambove necarcinoid syndrome (mamiriro umo bundu rinoburitsa serotonin). chirwere cheshuga, kuwedzerwa kweropa, hyperthyroidism (yakanyanyisa utachiona), kudzvinyirira immune (matambudziko nema immune system), pheochromocytoma (bundu readrenal gland), pfari, kana chirwere cheitsvo.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora linezolid, danaidza chiremba wako.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti uri kutora linezolid.
  • kana iwe uine phenylketonuria (PKU, chinzvimbo chakagarwa nhaka umo chikafu chakasarudzika chinofanira kuteverwa kudzivirira kudzora kwepfungwa), iwe unofanirwa kuziva kuti kumiswa kwemuromo kune aspartame inoumba phenylalanine.

Dzivisa kudya kana kunwa zvakawanda zvekudya uye zvinwiwa zvine tyramine uchitora linezolid. Kudya uye zvinwiwa zvakatorwa, kusvuta, kana kuvirisa kazhinji zvine tyramine. Izvi zvekudya nezvinwiwa zvinosanganisira zvinwiwa zvinodhaka, kunyanya hwahwa, Chianti, nehumwe waini tsvuku; doro risina doro; cheeses (kunyanya akasimba, akura, kana akagadziriswa mhando); sauerkraut; yogati; mazambiringa akaomeswa; mabhanana; kirimu yakasviba; pickled herring; chiropa (kunyanya chiropa chehuku); nyama dzakaomeswa uye soseji (inosanganisira yakaoma salami uye pepperoni); maonde akakangwa; avocado; soy muto; Teki; mbiriso inobvisa; Zvigadzirwa zvepapai (kusanganisira zvimwe zvinopa nyama); fava beans; nehupamhi bhinzi pods.


Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Linezolid inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • manyoka
  • musoro
  • kusvotwa
  • kurutsa
  • kurwadziwa nemudumbu
  • chinja munzira iyo zvinhu zvinonaka
  • mapundu
  • kuvava
  • dzungu
  • zvigamba zvichena mumuromo
  • kutsamwa, kupisa, kana kuchenesa kwemukadzi
  • shanduko muvara rerurimi kana mazino

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • mikoko, mapundu, kuchenjera, kunetseka kufema kana kumedza, kuzvimba kwechiso, huro, rurimi, miromo, maziso, maoko, tsoka, makumbo, kana makumbo ezasi, kutyisa
  • kuputika kana kubvisa ganda
  • kudzokorora kusvotwa uye kurutsa; kukurumidza kufema; kuvhiringidzika; kunzwa kuneta
  • kurwadziwa, chiveve, kana kushaya simba mumaoko, tsoka, kana zvimwe zvikamu zvemuviri
  • manyoka akanyanya (emvura kana ane tsvina) ayo anogona kuitika aine kana pasina fivha uye mudumbu maronda (anogona kuitika kusvika pamwedzi miviri kana kupfuura mushure mekurapwa kwako)
  • kubuda ropa zvisina kujairika kana kupwanya
  • shanduko pakuona kwemavara, kusaona zvakanaka, kana kumwe kuchinjika muchiono
  • pfari

Linezolid inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.


Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nechiedza uye kupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Linezolid yekumisa pamuromo inofanira kushandiswa mukati memazuva makumi maviri nerimwe.

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help.Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira kumwe kuongorora kweropa kuti atarise mhinduro yemuviri wako kune linezolid.

Usarega mumwe munhu achitora mushonga wako. Yako tsamba yekunyora inogona kunge isingazadzikiswe. Kana iwe uchiri nezviratidzo zvehutachiona mushure mekupedza iyo linezolid, fonera chiremba wako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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