Munyori: Janice Evans
Zuva Rekusika: 4 Chikunguru 2021
Gadziridza Zuva: 15 Mbudzi 2024
Anonim
HIV therapy: Maraviroc. Mechanism of Action and Resistance【USMLE, Pharmacology】
Vhidhiyo: HIV therapy: Maraviroc. Mechanism of Action and Resistance【USMLE, Pharmacology】

Zvemukati

Maraviroc inogona kukanganisa chiropa chako. Iwe unogona kusangana neanogadzirisa maitiro kune maraviroc usati waita kukuvara kwechiropa. Udza chiremba wako kana iwe wakambove kana uine hepatitis kana chimwe chirwere chechiropa. Kana iwe ukasangana nechimwe cheanotevera zviratidzo, rega kutora maraviroc uye dana chiremba wako nekukurumidza: itchy rash; yero yeganda kana maziso; weruvara-dema (yeti-mavara) weti; kurutsa; kana kumusoro kwepamusoro kurudyi kwemudumbu.

Maraviroc inogona kukonzera kukonzeresa zvakanyanya, izvo zvinogona kutyisidzira hupenyu. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiita. kupindwa nechando; flu-kunge zviratidzo; mhasuru kana kurwadziwa kwemajoini; mapundu kana maronda mumuromo; kuzvimba, kutsvuka, kubvisa, kana kubvaruka ganda; kutsvuka kana kuzvimba kwemaziso; kuzvimba kwemuromo, kumeso, kana miromo; kunetseka kufema; kurwadziwa, kurwadziwa, kana kupfava kurudyi kurudyi pazasi pembabvu; kana kurasikirwa nenzara.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira mimwe bvunzo kuti atarise mhinduro yemuviri wako kune maraviroc.


Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (reMedicine Gwara) paunotanga kurapwa ne maraviroc uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekutora maraviroc.

Maraviroc inoshandiswa pamwe chete nemimwe mishonga yekurapa imwe mhando yehutachiona hwehutachiona hwehutachiona hweHIV muvanhu vakuru nevana vanorema anosvika 4.4 lb (2 kg). Maraviroc iri mukirasi yemishonga inonzi HIV kupinda uye fusion inhibitors. Inoshanda nekuderedza huwandu hweHIV muropa. Kunyangwe maraviroc isingarape HIV, inogona kudzikisira mukana wako wekuwana immunodeficiency syndrome (AIDS) nezvirwere zvine chekuita neHIV senge hutachiona hwakakomba kana gomarara. Kutora mishonga iyi pamwe nekuita bonde rakachengeteka uye nekuita mamwe mararamire shanduko kunogona kudzora njodzi yekutapurirana (kuparadzira) hutachiona hweHIV kune vamwe vanhu.


Maraviroc inouya sehwendefa uye mhinduro (mvura) kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kaviri pazuva. Tora maraviroc kwakatenderedza nguva dzakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora maraviroc chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Kumedza maraviroc mahwendefa akazara; usatsemure, kutsenga, kana kuvapwanya.

Shandisa imwe yemajekiseni emuromo akauya nemushonga kuyera mhinduro. Shandisa diki (3-mL) sirinji yemuromo kana dosi yako iri 2.5 mL kana zvishoma uye shandisa hombe (10-mL) sirinji yemuromo kana dosi rako rakakura kupfuura 2.5 mL. Kumbira chiremba wako kana wemishonga kana iwe uine chero mibvunzo nezve maitiro ekuyera dosi yako nesiringi. Tevedza rairo dzemugadziri nezve mashandisiro uye nekuchenesa sirinji yemuromo.

Kana iwe urikupa mhinduro kumwana, isa muromo wejekiseni remuromo mumuromo wemwana uchipesana nemukati medama. Zvishoma nezvishoma sundira plunger yose nzira pasi kuti upe iyo yese mishonga mune yemuromo sirinji. Ita shuwa kuti mwana ane nguva yakakwana yekumedza mhinduro.


Ramba uchitora maraviroc kunyangwe iwe uchinzwa zvakanaka. Usarega kutora maraviroc usina kutaura nachiremba wako. Kana iwe ukarasikirwa nemadhizaini, tora zvishoma pane yakatarwa dosi, kana kurega kutora maraviroc, mamiriro ako anogona kuve akaoma kurapa. Kana chako kupihwa maraviroc chatanga kudzikira, tora zvimwe kubva kuna chiremba wako kana wemishonga.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora maraviroc,

  • udza chiremba wako uye wemishonga kana uri weergoria kune maraviroc, chero mimwe mishonga, kana chero chinhu chinowanikwa mumapiritsi e maraviroc kana mhinduro. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: antifungal mishonga yakadai ketoconazole (Nizoral) uye itraconazole (Onmel, Sporanox); clarithromycin (Biaxin, muPrevpac); mishonga yekurapa HIV kana AIDS; mishonga yekurapa yakakwira BP; idelalisib (Zydelig); mimwe mishonga yekurapa pfari yakadai se carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital (Luminal), uye phenytoin (Dilantin, Phenytek); nefazodone; ribociclib (Kisqali); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, Rifamate, vamwe); uye telithromycin (haichawanikwi muU.S.; Ketek). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort. Haufanire kutora wort yeSt.John panguva yekurapwa kwako ne maraviroc.
  • udza chiremba wako kana wakambove neBP shoma, kurwadziwa pachipfuva, chirwere cheshuga, chirwere chemwoyo, cholesterol yakakwira kana mafuta muropa, kana chirwere chemoyo kana cheitsvo.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora maraviroc, fonera chiremba wako. Iwe haufanire kuyamwa kana uine hutachiona hweHIV kana kana uri kutora maraviroc.
  • iwe unofanirwa kuziva kuti mafuta emuviri wako anogona kuwedzera kana kuenda kunzvimbo dzakasiyana dzemuviri wako, senge mazamu ako nechekumusoro kumashure, paunenge uchitora maraviroc.
  • iwe unofanirwa kuziva kuti maraviroc inogona kukonzeresa dzungu, huremu husina musoro, kana kufenda kana iwe uchimuka nekukurumidza kubva panzvimbo yekunyepa. Kuti ubatsire kunzvenga dambudziko iri, simuka pamubhedha zvishoma nezvishoma, uchizorora tsoka dzako pasi kwemaminetsi mashoma usati wasimuka. Usatyaire mota kana kushandisa michina inorema kana uine dzungu uchitora maraviroc.
  • Unofanirwa kuziva kuti paunenge uchinwa mishonga yekurapa hutachiona hweHIV, immune system yako inogona kusimba uye yotanga kurwisa zvimwe zvirwere zvaive mumuviri wako kare. Izvi zvinogona kukonzera kuti iwe uwedzere zviratidzo zveawo hutachiona. Kana iwe uine zvitsva kana kuwedzera zviratidzo mushure mekutanga kurapwa ne maraviroc, ita shuwa yekuudza chiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira, uyezve tora iyo inotevera dosi panguva yakatarwa. Nekudaro, kana iri isingasviki maawa matanhatu pamberi peyadhi yako inotevera, ruka iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Maraviroc inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • chikosoro, runny mhuno, kana zvimwe zvinotonhora zviratidzo
  • mhasuru kana kurwadziwa kwemajoini
  • kurwadziwa, kupisa, chiveve, kana kugwinha mumaoko kana tsoka
  • dzungu
  • manyoka
  • kuvimbiswa
  • kunorwadza kana kuoma kuita weti
  • maronda machena uye / kana kurwadziwa mumuromo kana esophagus (chubhu pakati pemuromo nedumbu)
  • kunetseka kurara kana kuramba wakarara
  • kurara kufamba, kurara kutaura, kurara zvinotyisa, kana kuita muhope dzako

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiona chimwe chezviratidzo izvi, kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuti uwane kurapwa kwekukurumidzira:

  • kurwadziwa pahuro, fivha, kutonhora, kana zvimwe zviratidzo zvehutachiona
  • kurwadziwa pachifuva, kumanikidzwa, kana kusagadzikana
  • kurwadziwa mune rimwe kana maviri maoko, musana, mutsipa, shaya, kana mudumbu
  • mweya wekufema
  • vangadikitira

Maraviroc inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Rasa chero mhinduro isina kushandiswa yemuromo mazuva makumi matanhatu mushure mekutanga kuvhura bhodhoro.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • dzungu, huremu husina musoro, kana kupera simba kana uchisimuka nekukurumidza kubva panzvimbo yekunyepa

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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Yekupedzisira Yakagadziridzwa - 01/15/2021

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