Romidepsin jekiseni

Zvemukati

• Usati wagamuchira jekiseni reromidepsin,
• Romidepsin jekiseni inogona kukonzeresa mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

Romidepsin jekiseni rinoshandiswa kurapa rakapatsanurwa T-cell lymphoma (CTCL; boka remagomarara e immune immune ayo anotanga kuoneka seganda rashes) muvanhu vakatorapwa nechero imwe imwe mishonga. Romidepsin jekiseni rinoshandiswawo kurapa peripheral T-cell lymphoma (PTCL; rudzi rweiyo isiri-Hodgkin's lymphoma) mune vanhu vakatorapwa nemumwe mushonga. Romidepsin jekiseni iri mukirasi yemishonga inonzi histone deacetylase (HDAC) inhibitors. Inoshanda nekuderedza kukura kwekenza masero.

Romidepsin jekiseni inouya sehupfu hunofanira kusanganiswa nemvura kuti ijojwe mukati (mutsinga) kweanenge maawa mana-nguva nachiremba kana mukoti. Inowanzo kupihwa pamazuva 1, 8, uye 15 ezuva 28-kutenderera. Izvi zvinogona kudzokororwa chero bedzi mushonga uchiramba uchishanda uye usingakonzere zvakakomba mhedzisiro.

Taura nachiremba wako nezve chero mhedzisiro yaunosangana nayo panguva yekurapwa kwako nejomidepsin jekiseni. Kana iwe ukawana mamwe akanyanya mhedzisiro mhedzisiro, chiremba wako anogona kumisa kurapwa kwako zvachose kana kwechinguva uye / kana anogona kudzikisira yako dose.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wagamuchira jekiseni reromidepsin,

• udza chiremba wako uye wemishonga kana uri weergoria kune jekiseni reromidepsin, chero mimwe mishonga, kana chero chinhu chinosanganiswa mujekiseni reromidepsin. Kumbira wemishonga wako kana tarisa ruzivo rwevarwere kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mamwe maantibhakitiriya akadai clarithromycin (Biaxin), erythromycin (EES, E-Mycin, Erythrocin), moxifloxacin (Avelox), uye telithromycin (Ketek); anticoagulants (ropa rakatetepa) senge warfarin (Coumadin, Jantoven); antifungals senge itraconazole (Sporanox), ketoconazole (Nizoral), uye voriconazole (Vfend); cisapride (Propulsid) (haisipo muU.S.); dexamethasone; mishonga yehutachiona hwehutachiwana hwevanhu (HIV) senge atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (muKaletra, Norvir), uye saquinavir (Invirase); mishonga yekurova kwemoyo zvisina kufanira senge amiodarone (Cordarone), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid, Pronestyl), quinidine (Quinidex), uye sotalol (Betapace, Betapace AF); mimwe mishonga yekubatwa senge carbamazepine (Epitol, Equetro, Tegretol), phenobarbital, uye phenytoin (Dilantin); nefazodone; pimozide (Orap); rifabutin (Mycobutin); rifampin (Rifadin, muRifamate, muRifater, Rimactane); rifapentine (Priftin); sparfloxacin (Zagam); kana thioridazine (Mellaril). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mimwe mishonga yakawanda inogona zvakare kusangana nejojo ​​ye romidepsin, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana uine kusvotwa, kurutsa, kana kuita manyoka usati watanga kurapwa kwako nejomidepsin jekiseni. Uyezve udza chiremba wako kana iwe kana wakambove nenguva yakareba yeQT (chinetso chisingawanzo mwoyo chinogona kukonzeresa kurova kwemoyo zvisina kufanira, kufenda, kana kufa kamwe kamwe), kurova kwemoyo zvisina kujairika kana nekukurumidza, zvakawandisa kana kushomeka potasium kana magnesium muropa rako. , hepatitis B (HBV; hutachiona hunokanganisa chiropa uye hunogona kukonzera kukuvara kwechiropa kwakakomba kana gomarara rechiropa), Epstein Barr virus (EBV; utachiona hweherpes hunokonzera hutachiona mononucleosis uye hunobatana nemamwe maronda egomarara), kana chiropa, itsvo, kana chirwere chemoyo.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Chiremba wako anogona kutarisa kuti aone kana une pamuviri usati watanga kurapwa kwako. Iwe unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako neromidepsin jekiseni uye kweinenge mwedzi mumwe mushure meyako yekupedzisira dosi. Nekudaro, iwe haufanire kushandisa mahormone (estrogen) mishonga yekudzivirira (mapiritsi ekudzivirira kubereka, zvigamba, mhete, mapiritsi, kana majekiseni) nekuti jekiseni reromidepsin rinogona kumisa iyi mishonga kushanda sezvavanofanira. Kana iwe uri murume ane mukadzi mukadzi waunogona kuve nepamuviri, ita chokwadi chekushandisa kuberekwa panguva yekurapa kwako neRomidepsin jekiseni uye kweinenge mwedzi mumwe mushure meyako yekupedzisira dosi. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa. Kana iwe ukava nepamuviri iwe uchigamuchira romidepsin jekiseni, fonera chiremba wako. Romidepsin jekiseni inogona kukuvadza fetus. Iwe haufanire kuyamwisa panguva yekurapa kwako nejomidepsin jekiseni uye kweinenge 1 vhiki mushure meyako yekupedzisira dosi.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikugamuchira jekiseni romidepsin.

Ive neshuwa yekunwa mvura yakawanda kwemazuva matatu kana matatu uchitevera imwe neimwe yedosi yejomidepsin jekiseni.

Taura nachiremba wako nezve kudya mazambiringa uye kunwa jisi remuzambiringa paunenge uchigamuchira mushonga uyu.

Romidepsin jekiseni inogona kukonzeresa mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kusvotwa
• kurutsa
• manyoka
• kuvimbiswa
• kurwadziwa nemudumbu
• maronda emuromo
• musoro
• yakachinja pfungwa yekuravira
• kurasikirwa nenzara
• kuvava

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

• kuneta kana kushaya simba
• ganda rakachenuruka
• mweya wekufema
• kurwadziwa pachipfuva
• kurova kwemoyo zvisina kujairika
• kunzwa dzungu kana kupera simba
• kupwanya kuri nyore kana kubuda ropa
• fivhiri, kukosora, zviratidzo zvakaita sehururu, kuputika kwemasuru, kupisa pakuda kuita weti, kuwedzera matambudziko eganda, uye zvimwe zviratidzo zvehutachiona (zvinogona kusvika mazuva makumi matatu mushure mekurapwa kwako)
• mapundu
• kuputika kana kubvisa ganda
• kuzvimba kwemaoko, tsoka, makumbo, kana makumbo ezasi

Romidepsin jekiseni inogona kukonzera matambudziko ekubereka. Taura nachiremba wako nezve njodzi dzekugamuchira mushonga uyu kana uchida kuva nevana.

Romidepsin jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune romidepsin jekiseni.

Bvunza wako wemishonga chero mibvunzo iwe unayo nezve romidepsin jekisi.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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